The network for 'negative regulation of protein depolymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein depolymerization

Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.

Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
BOI1Boi1p0.677
BMH1Bmh1p0.652
CLB3Clb3p0.398
CAP2Cap2p0.358
ABP1Abp1p0.261
CDC14Cdc14p0.201
LAS17Las17p0.201
KAR9Kar9p0.180
SRV2Srv2p0.158
CLB1Clb1p0.129
MYO5Myo5p0.122
BMH2Bmh2p0.115
NDD1Ndd1p0.106
GYL1Gyl1p0.096
ARC40Arc40p0.085
ASE1Ase1p0.082
BNI1Bni1p0.077
LSB1Lsb1p0.074
BBC1Bbc1p0.068
ACM1Acm1p0.068
CIN8Cin8p0.067
SWE1Swe1p0.062
YPR1Ypr1p0.055
VIK1Vik1p0.054
HST3Hst3p0.049
NBL1Nbl1p0.047
CDC24Cdc24p0.044
KCC4Kcc4p0.037
SLA2Sla2p0.037
SLK19Slk19p0.036
AIP1Aip1p0.035
ADE16Ade16p0.034
SAC6Sac6p0.034
ORC6Orc6p0.033
SRD1Srd1p0.031
TOF2Tof2p0.031
IRC8Irc8p0.030
SIC1Sic1p0.030
BSP1Bsp1p0.029
EXO70Exo70p0.029
YAR068Whypothetical protein0.028
CLB4Clb4p0.027
DYN1Dyn1p0.026
KIP1Kip1p0.025
YOL038C-Ahypothetical protein0.025
HXT3Hxt3p0.024
BEM3Bem3p0.024
NUF2Nuf2p0.024
MDM20Mdm20p0.024
CDC28Cdc28p0.023
YLR162Whypothetical protein0.023
PTI1Pti1p0.023
CUP1-1Cup1-1p0.023
BUD6Bud6p0.023
YLR264C-Ahypothetical protein0.023
BNR1Bnr1p0.022
CAP1Cap1p0.022
LEU2Leu2p0.022
YPL014Whypothetical protein0.021
SPL2Spl2p0.021
NUD1Nud1p0.020
PFY1Pfy1p0.020
ARP10Arp10p0.020
ADH2Adh2p0.020
ASK1Ask1p0.020
FIR1Fir1p0.019
TWF1Twf1p0.019
UBP7Ubp7p0.019
SGO1Sgo1p0.019
PIL1Pil1p0.019
FUS2Fus2p0.019
YAR066Whypothetical protein0.019
MER1Mer1p0.019
CLB6Clb6p0.018
YIL151Chypothetical protein0.018
HPF1Hpf1p0.018
ARP3Arp3p0.018
INN1Inn1p0.018
SPR6Spr6p0.018
ATP6Atp6p0.018
ARC35Arc35p0.018
YTA6Yta6p0.018
NUP157Nup157p0.018
CKS1Cks1p0.018
DAM1Dam1p0.017
NIS1Nis1p0.017
MPS1Mps1p0.017
ARG8Arg8p0.017
YBR013Chypothetical protein0.017
CHA1Cha1p0.017
YFR016Chypothetical protein0.017
BIM1Bim1p0.016
BFA1Bfa1p0.016
SPS4Sps4p0.016
WSC4Wsc4p0.016
CPD1Cpd1p0.016
YNL058Chypothetical protein0.016
AUA1Aua1p0.016
YLR042Chypothetical protein0.015
KAR3Kar3p0.015
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
exo84CG6095 gene product from transcript CG6095-RA0.946
DetDeterin0.895
sec8CG2095 gene product from transcript CG2095-RA0.864
CG32038CG32038 gene product from transcript CG32038-RA0.823
brubrunelleschi0.752
vibvibrator0.651
Klp67AKinesin-like protein at 67A0.487
aspabnormal spindle0.482
diadiaphanous0.443
beta-Specbeta Spectrin0.333
Spc25CG7242 gene product from transcript CG7242-RA0.310
stisticky0.275
marsCG17064 gene product from transcript CG17064-RB0.269
slssallimus0.218
htshu li tai shao0.197
tefteflon0.193
WASpCG1520 gene product from transcript CG1520-RA0.162
alpha-Specalpha Spectrin0.161
MarfMitochondrial assembly regulatory factor0.158
nebnebbish0.153
Rae1CG9862 gene product from transcript CG9862-RA0.150
Poc1Proteome of centrioles 10.149
fwsfour way stop0.130
aslasterless0.116
CG31224CG31224 gene product from transcript CG31224-RA0.110
Sop2Suppressor of profilin 20.096
btzbarentsz0.093
ana3anastral spindle 30.092
CG11299CG11299 gene product from transcript CG11299-RA0.090
flwflapwing0.089
aretarrest0.086
Spc105RSpc105-related0.085
spd-2spindle defective 20.080
ballballchen0.079
chercheerio0.077
sas-6spindle assembly abnormal 60.076
bondjames bond0.072
borrborealin-related0.066
upupheld0.066
Rbsn-5Rabenosyn-50.066
Cenp-CCG31258 gene product from transcript CG31258-RA0.065
ifcinfertile crescent0.064
otuovarian tumor0.063
Grip128CG9201 gene product from transcript CG9201-RB0.062
opa1-likeoptic atrophy 1-like0.062
Sas-4CG10061 gene product from transcript CG10061-RA0.060
poloCG12306 gene product from transcript CG12306-RA0.059
mtrmmatrimony0.056
Cog7CG31040 gene product from transcript CG31040-RA0.054
PpcsPhosphopantothenoylcysteine synthetase0.052
Dhc64CDynein heavy chain 64C0.051
KhcKinesin heavy chain0.049
MrtfMyocardin-related transcription factor0.048
Vrp1Verprolin 10.048
CG10722CG10722 gene product from transcript CG10722-RA0.046
Dap160Dynamin associated protein 1600.042
vps2CG14542 gene product from transcript CG14542-RA0.039
lkb1CG9374 gene product from transcript CG9374-RJ0.039
pblpebble0.037
flrflare0.036
ncdnon-claret disjunctional0.036
twinCG31137 gene product from transcript CG31137-RB0.035
Trc8CG2304 gene product from transcript CG2304-RB0.035
GmdGDP-mannose 4,6-dehydratase0.034
encencore0.033
prosprospero0.033
Cep135CG17081 gene product from transcript CG17081-RB0.033
CG4617CG4617 gene product from transcript CG4617-RA0.032
sds22CG5851 gene product from transcript CG5851-RA0.032
maelmaelstrom0.032
DlicDynein light intermediate chain0.032
Gef26CG9491 gene product from transcript CG9491-RB0.031
Letm1CG4589 gene product from transcript CG4589-RB0.031
Ndc80CG9938 gene product from transcript CG9938-RA0.030
DAAMDishevelled Associated Activator of Morphogenesis0.029
zpgzero population growth0.029
piepineapple eye0.029
austaustralin0.029
LaspCG3849 gene product from transcript CG3849-RB0.028
Hsp83Heat shock protein 830.028
taitaiman0.028
Drp1Dynamin related protein 10.027
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.026
nudECG8104 gene product from transcript CG8104-RB0.025
larpLa related protein0.025
eglegalitarian0.025
CG5491CG5491 gene product from transcript CG5491-RA0.025
vasvasa0.025
Orc2Origin recognition complex subunit 20.025
wupAwings up A0.024
jarjaguar0.024
RRoughened0.024
pavpavarotti0.023
Rbp9RNA-binding protein 90.023
TsCG3181 gene product from transcript CG3181-RA0.022
trctricornered0.022
sec5CG8843 gene product from transcript CG8843-RA0.022
cidcentromere identifier0.022
Prp38pre-mRNA processing factor 380.022
Grip75CG6176 gene product from transcript CG6176-RA0.022
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AURKBaurora kinase B0.355
INCENPinner centromere protein antigens 135/155kDa0.317
BIRC5baculoviral IAP repeat containing 50.284
CKS2CDC28 protein kinase regulatory subunit 20.221
APCadenomatous polyposis coli0.213
ITGB4integrin, beta 40.197
TPM1tropomyosin 1 (alpha)0.179
TRIM63tripartite motif containing 630.174
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.167
KIF23kinesin family member 230.150
RACGAP1Rac GTPase activating protein 10.149
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.143
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.136
CDK1cyclin-dependent kinase 10.132
MYPNmyopalladin0.126
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.123
TPM2tropomyosin 2 (beta)0.122
CDCA8cell division cycle associated 80.118
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.100
EXOC1exocyst complex component 10.087
CORO1Ccoronin, actin binding protein, 1C0.083
GLIS2GLIS family zinc finger 20.073
PDLIM7PDZ and LIM domain 7 (enigma)0.066
MYH9myosin, heavy chain 9, non-muscle0.061
TPM4tropomyosin 40.059
ANKRD28ankyrin repeat domain 280.059
CENPEcentromere protein E, 312kDa0.056
CDK2cyclin-dependent kinase 20.053
PSEN2presenilin 2 (Alzheimer disease 4)0.052
DSTdystonin0.052
GRB2growth factor receptor-bound protein 20.049
KIF1Bkinesin family member 1B0.045
KIF20Akinesin family member 20A0.043
RIPK3receptor-interacting serine-threonine kinase 30.042
GAS2L3growth arrest-specific 2 like 30.039
WASLWiskott-Aldrich syndrome-like0.039
EXOC7exocyst complex component 70.033
ATF7IPactivating transcription factor 7 interacting protein0.032
IQGAP1IQ motif containing GTPase activating protein 10.032
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.032
SPTBN1spectrin, beta, non-erythrocytic 10.031
MARK2MAP/microtubule affinity-regulating kinase 20.031
CCNA2cyclin A20.030
DISC1disrupted in schizophrenia 10.030
CENPJcentromere protein J0.030
ADRBK1adrenergic, beta, receptor kinase 10.028
LBRlamin B receptor0.028
STILSCL/TAL1 interrupting locus0.026
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.025
SVILsupervillin0.024
ITSN1intersectin 1 (SH3 domain protein)0.024
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.024
EXOC2exocyst complex component 20.024
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.023
SOS1son of sevenless homolog 1 (Drosophila)0.023
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.022
SASS6spindle assembly 6 homolog (C. elegans)0.022
MACF1microtubule-actin crosslinking factor 10.022
XPO1exportin 1 (CRM1 homolog, yeast)0.022
ERBB2IPerbb2 interacting protein0.021
ACTA1actin, alpha 1, skeletal muscle0.020
SUFUsuppressor of fused homolog (Drosophila)0.020
TEX11testis expressed 110.020
CTTNcortactin0.019
CCDC85Acoiled-coil domain containing 85A0.019
KIF5Bkinesin family member 5B0.018
ZRANB1zinc finger, RAN-binding domain containing 10.018
C6orf211chromosome 6 open reading frame 2110.017
ACTN1actinin, alpha 10.016
TUBGCP5tubulin, gamma complex associated protein 50.016
JUPjunction plakoglobin0.016
TNIKTRAF2 and NCK interacting kinase0.016
NRASneuroblastoma RAS viral (v-ras) oncogene homolog0.015
ZFP106zinc finger protein 106 homolog (mouse)0.014
OPTNoptineurin0.014
GPSM2G-protein signaling modulator 20.014
VCLvinculin0.014
MAP3K3mitogen-activated protein kinase kinase kinase 30.013
MYL9myosin, light chain 9, regulatory0.013
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.013
GULP1GULP, engulfment adaptor PTB domain containing 10.012
CYLDcylindromatosis (turban tumor syndrome)0.012
ARIH2ariadne homolog 2 (Drosophila)0.012
DLGAP5discs, large (Drosophila) homolog-associated protein 50.012
CNN1calponin 1, basic, smooth muscle0.012
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.012
CP110CP110 protein0.011
COL17A1collagen, type XVII, alpha 10.011
PBKPDZ binding kinase0.011
KIF2Ckinesin family member 2C0.011
ZYXzyxin0.011
PHLDB2pleckstrin homology-like domain, family B, member 20.011
PRKCAprotein kinase C, alpha0.011
CD164CD164 molecule, sialomucin0.011
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.011
ATG4BATG4 autophagy related 4 homolog B (S. cerevisiae)0.011
SNX9sorting nexin 90.011
AKAP11A kinase (PRKA) anchor protein 110.010
WDR1WD repeat domain 10.010
KIF20Bkinesin family member 20B0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Anlnanillin, actin binding protein0.953
Ctnnb1catenin (cadherin associated protein), beta 10.947
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.946
Prc1protein regulator of cytokinesis 10.943
Macf1microtubule-actin crosslinking factor 10.882
Ccnb1cyclin B10.874
Cdk1cyclin-dependent kinase 10.832
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.800
Kif20akinesin family member 20A0.718
Itgb1integrin beta 1 (fibronectin receptor beta)0.714
Dclk1doublecortin-like kinase 10.619
Ccna2cyclin A20.596
Rac1RAS-related C3 botulinum substrate 10.529
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.462
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.450
Capzbcapping protein (actin filament) muscle Z-line, beta0.447
Nr2e1nuclear receptor subfamily 2, group E, member 10.443
Racgap1Rac GTPase-activating protein 10.441
Trim63tripartite motif-containing 630.373
Ckap2cytoskeleton associated protein 20.364
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.362
Wdr1WD repeat domain 10.361
Birc5baculoviral IAP repeat-containing 50.360
Hif1ahypoxia inducible factor 1, alpha subunit0.355
Nf1neurofibromatosis 10.344
Hmmrhyaluronan mediated motility receptor (RHAMM)0.315
Csrp1cysteine and glycine-rich protein 10.313
Top2atopoisomerase (DNA) II alpha0.302
BrafBraf transforming gene0.299
Kif11kinesin family member 110.287
Plk1polo-like kinase 1 (Drosophila)0.278
Kif22kinesin family member 220.276
Ect2ect2 oncogene0.270
Mapre1microtubule-associated protein, RP/EB family, member 10.260
Mki67antigen identified by monoclonal antibody Ki 670.257
Actr3ARP3 actin-related protein 3 homolog (yeast)0.254
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.252
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.251
Ccnb2cyclin B20.238
Clasp1CLIP associating protein 10.234
Lims1LIM and senescent cell antigen-like domains 10.226
Trim55tripartite motif-containing 550.200
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.192
Rap1bRAS related protein 1b0.187
Gsk3bglycogen synthase kinase 3 beta0.186
Kif4kinesin family member 40.184
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.178
Kif23kinesin family member 230.166
Spna2spectrin alpha 20.159
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.157
Dcxdoublecortin0.148
Adam10a disintegrin and metallopeptidase domain 100.144
Smad3MAD homolog 3 (Drosophila)0.144
Kif2akinesin family member 2A0.139
Kif2ckinesin family member 2C0.138
Pdlim5PDZ and LIM domain 50.137
Cltcclathrin, heavy polypeptide (Hc)0.134
Bzw1basic leucine zipper and W2 domains 10.133
Tmod3tropomodulin 30.133
Trp53transformation related protein 530.131
Aurkaaurora kinase A0.130
Rod1ROD1 regulator of differentiation 1 (S. pombe)0.130
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.129
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.127
Lmnalamin A0.124
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.123
Lmnb1lamin B10.119
Brca1breast cancer 10.119
Smc2structural maintenance of chromosomes 20.113
Slc25a24solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 240.113
Nefmneurofilament, medium polypeptide0.112
Dlgap5discs, large (Drosophila) homolog-associated protein 50.105
Dbnldrebrin-like0.097
Fgfr2fibroblast growth factor receptor 20.096
Gtse1G two S phase expressed protein 10.094
Capza2capping protein (actin filament) muscle Z-line, alpha 20.093
Smc4structural maintenance of chromosomes 40.093
Itga3integrin alpha 30.092
Shc3src homology 2 domain-containing transforming protein C30.091
Msnmoesin0.090
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.088
Mastlmicrotubule associated serine/threonine kinase-like0.087
Lrrk2leucine-rich repeat kinase 20.086
Arhgap1Rho GTPase activating protein 10.085
Trp63transformation related protein 630.085
Rhoaras homolog gene family, member A0.080
Hmgb2high mobility group box 20.077
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.076
Arpc4actin related protein 2/3 complex, subunit 40.076
Sept2septin 20.076
Ube2cubiquitin-conjugating enzyme E2C0.076
Mstnmyostatin0.076
Sept7septin 70.073
Med12mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)0.072
Gnb1guanine nucleotide binding protein (G protein), beta 10.072
Gata3GATA binding protein 30.070
Fgfbp1fibroblast growth factor binding protein 10.068
Stk11serine/threonine kinase 110.067
Ptgs2prostaglandin-endoperoxide synthase 20.065
Dtnadystrobrevin alpha0.065
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.019
Tpm3tropomyosin 3, gamma0.016
Mapre1microtubule-associated protein, RP/EB family, member 10.014
Tpm4tropomyosin 40.013
Acta2smooth muscle alpha-actin0.011
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.011