The network for 'regulation of purine nucleotide catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of purine nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.

NameDescriptionProbabilityFunc Analog Organism
STE5Ste5p0.453
GYL1Gyl1p0.259
RHO1Rho1p0.247
STE11Ste11p0.205
SUI3Sui3p0.156
GDI1Gdi1p0.147
FAR1Far1p0.146
STE4Ste4p0.146
ROM2Rom2p0.139
SEC16Sec16p0.120
TRS65Trs65p0.112
STI1Sti1p0.096
AVO1Avo1p0.095
CDC24Cdc24p0.095
MKK1Mkk1p0.094
YPT53Ypt53p0.079
VPS15Vps15p0.078
TOM1Tom1p0.072
STE20Ste20p0.061
KEL1Kel1p0.061
MDS3Mds3p0.057
MON1Mon1p0.057
FUS2Fus2p0.057
MRC1Mrc1p0.056
GCD6Gcd6p0.055
FIR1Fir1p0.055
PTP2Ptp2p0.054
GIC2Gic2p0.054
HYP2Hyp2p0.052
TSC11Tsc11p0.051
BET3Bet3p0.051
MSB3Msb3p0.050
VTA1Vta1p0.049
BEM3Bem3p0.046
PEP5Pep5p0.046
STT4Stt4p0.046
SSK1Ssk1p0.045
KOG1Kog1p0.044
FKH1Fkh1p0.043
CHS1Chs1p0.042
STE2Ste2p0.042
SAR1Sar1p0.042
PKC1Pkc1p0.042
ATG20Atg20p0.041
SLH1Slh1p0.040
MRS6Mrs6p0.039
HCH1Hch1p0.039
SEC53Sec53p0.039
MBF1Mbf1p0.039
YNL108Chypothetical protein0.038
MKK2Mkk2p0.038
MCM3Mcm3p0.038
TMN3Tmn3p0.038
BUD14Bud14p0.037
PAR32Par32p0.037
SOG2Sog2p0.037
VPS5Vps5p0.037
YPP1Ypp1p0.037
TCP1Tcp1p0.037
YPT52Ypt52p0.037
SSK2Ssk2p0.037
BST1Bst1p0.036
CHS5Chs5p0.036
TOR1Tor1p0.036
YDJ1Ydj1p0.036
CCZ1Ccz1p0.036
SSA4Ssa4p0.036
YIR035Chypothetical protein0.036
ORC2Orc2p0.035
SLT2Slt2p0.035
NOP10Nop10p0.035
CDC50Cdc50p0.035
YJL144Whypothetical protein0.035
SPA2Spa2p0.035
INP52Inp52p0.035
SEC23Sec23p0.035
BUL1Bul1p0.034
SPR6Spr6p0.034
ITR2Itr2p0.034
COX13Cox13p0.034
TAO3Tao3p0.034
TSC10Tsc10p0.033
IST1Ist1p0.033
SSL2Ssl2p0.032
NEO1Neo1p0.032
CWC23Cwc23p0.032
GLO3Glo3p0.032
YDR186Chypothetical protein0.032
RGA2Rga2p0.032
DBF4Dbf4p0.032
SFB2Sfb2p0.031
PMI40Pmi40p0.031
APM4Apm4p0.031
BIT61Bit61p0.031
ARP10Arp10p0.030
RAT1Rat1p0.030
AKL1Akl1p0.030
INP53Inp53p0.030
URA6Ura6p0.030
AAP1Aap1p0.030
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sem-5Protein SEM-50.585
unc-45Protein UNC-450.370
snf-1Protein SNF-10.219
zyg-9Protein ZYG-90.217
spdl-1Protein SPDL-10.205
lag-1Protein LAG-10.192
tpxl-1Protein TPXL-10.187
CELE_F47G4.4Protein F47G4.40.168
egl-13Protein EGL-130.160
unc-53Protein UNC-530.157
zoo-1Protein ZOO-10.151
hda-1Protein HDA-10.142
pak-1Protein PAK-10.141
dnj-27Protein DNJ-270.131
egl-18Protein EGL-180.129
gpr-2Protein GPR-20.123
sup-17Protein SUP-170.117
lin-10Protein LIN-100.107
cyld-1Protein CYLD-10.104
cks-1Protein CKS-10.099
goa-1Protein GOA-10.098
rig-6Protein RIG-60.097
gpr-1Protein GPR-10.092
sad-1Protein SAD-10.089
T21B6.3Protein T21B6.30.089
zfp-1Protein ZFP-10.088
CELE_F25B4.5Protein F25B4.50.087
larp-5Protein LARP-50.086
Y55F3BR.8Protein Y55F3BR.80.083
hmr-1Protein HMR-10.082
bet-2Protein BET-20.081
tmc-2Protein TMC-20.081
rme-4Protein RME-40.080
rpb-7Protein RPB-70.076
rsbp-1Protein RSBP-10.075
rhgf-2Protein RHGF-20.074
F13H6.1Protein F13H6.10.072
mtm-9Protein MTM-90.072
ptp-1Protein PTP-10.071
elt-6Protein ELT-60.068
CELE_T10D4.6Protein T10D4.60.068
C53C9.2Protein C53C9.20.068
C11E4.6Protein C11E4.60.067
W05F2.6Protein W05F2.60.067
ttx-1Protein TTX-10.067
eef-1A.1Protein EEF-1A.10.064
sax-3Protein SAX-30.064
gar-3Protein GAR-30.064
unc-71Protein UNC-710.062
pat-3Protein PAT-30.062
myo-2Protein MYO-20.061
acr-2Protein ACR-20.061
lin-2Protein LIN-20.060
syd-9Protein SYD-90.058
T14B1.1Protein T14B1.10.058
unc-80Protein UNC-800.058
madf-5Protein MADF-50.056
etr-1Protein ETR-10.056
lin-45Protein LIN-450.055
unc-79Protein UNC-790.054
unc-54Protein UNC-540.052
gly-7Protein GLY-70.051
gei-8Protein GEI-80.051
egl-36Protein EGL-360.050
F35G2.1Protein F35G2.10.050
unc-26Protein UNC-260.049
gsa-1Protein GSA-10.049
unc-59Protein UNC-590.047
drr-2Protein DRR-20.046
F49E10.4Protein F49E10.40.045
pde-4Protein PDE-40.045
dgk-4Protein DGK-40.045
pdk-1Protein PDK-10.045
rps-2Protein RPS-20.044
C46C11.1Protein C46C11.10.044
chc-1Protein CHC-10.044
pkg-1Protein PKG-10.044
myo-1Protein MYO-10.044
skn-1Protein SKN-10.043
zfp-3Protein ZFP-30.043
egl-27Protein EGL-270.043
mrck-1Protein MRCK-10.043
pat-12Protein PAT-120.043
pqn-47Protein PQN-470.042
CELE_Y69A2AR.28Protein Y69A2AR.280.042
sel-12Protein SEL-120.042
hmg-1.1Protein HMG-1.10.042
unc-15Protein UNC-150.042
lpd-3Protein LPD-30.042
atg-11Protein ATG-110.041
tbb-4Protein TBB-40.041
ptp-4Protein PTP-40.041
sto-4Protein STO-40.040
stim-1Protein STIM-10.040
CELE_F08D12.1Protein F08D12.10.040
afd-1Protein AFD-10.040
lev-11Protein LEV-110.040
sym-4Protein SYM-40.040
R11A8.7Protein R11A8.70.039
C06G1.5Protein C06G1.50.039
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tnni2a.4troponin I, skeletal, fast 2a.40.801
tpm4tropomyosin 40.500
tnnc1btroponin C type 1b (slow)0.475
tnnt3btroponin T3b, skeletal, fast0.369
tnni1altroponin I, skeletal, slow like0.238
bidaBH3 interacting domain death agonist0.231
depdc1aDEP domain containing 1a0.226
hspa4aheat shock protein 4a0.218
tnni1btroponin I, skeletal, slow b0.208
smyhc2slow myosin heavy chain 20.197
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.164
gapdhglyceraldehyde-3-phosphate dehydrogenase0.159
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.145
dclk2doublecortin-like kinase 20.142
rtcd1RNA terminal phosphate cyclase domain 10.141
ilkintegrin linked kinase0.139
actn3bactinin alpha 3b0.137
ptprkprotein tyrosine phosphatase, receptor type, K0.133
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.132
pvalb4parvalbumin 40.128
ahctf1AT hook containing transcription factor 10.125
pvalb2parvalbumin 20.124
psen1presenilin 10.119
hsp90a.2heat shock protein 90-alpha 20.118
nme2b.2non-metastatic cells 2b.2, protein (NM23B) expressed in0.116
rtn1areticulon 1a0.115
si:rp71-39b20.7si:rp71-39b20.70.113
tp73tumor protein p730.112
trpv4transient receptor potential cation channel, subfamily V, member 40.111
actc1aactin, alpha, cardiac muscle 1a0.111
ldb3bLIM domain binding 3b0.111
pvalb1parvalbumin 10.109
stau1staufen, RNA binding protein, homolog 1 (Drosophila)0.108
optcopticin0.107
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.107
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.106
tpm3tropomyosin 30.103
vamp2vesicle-associated membrane protein 20.103
clic4chloride intracellular channel 40.102
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.101
gna14guanine nucleotide binding protein (G protein), alpha 140.101
tm9sf2transmembrane 9 superfamily member 20.101
krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.099
gclcglutamate-cysteine ligase, catalytic subunit0.097
eomesaeomesodermin homolog a0.096
zbtb4zinc finger and BTB domain containing 40.096
pacsin3protein kinase C and casein kinase substrate in neurons 30.095
tie1endothelium-specific receptor tyrosine kinase 10.095
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.095
ppargperoxisome proliferator activated receptor gamma0.094
junjun proto-oncogene0.093
s100v2S100 calcium binding protein V20.093
vdrbvitamin D receptor b0.093
prkcbp1lprotein kinase C binding protein 1, like0.092
tnnc2troponin C type 2 (fast)0.092
dnajaDnaJ (Hsp40) homolog, subfamily A member0.090
rrasrelated RAS viral (r-ras) oncogene homolog0.090
adrb2aadrenergic receptor, beta 2a0.090
myhz2myosin, heavy polypeptide 2, fast muscle specific0.090
rxrbbretinoid x receptor, beta b0.089
slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.089
acvr1bactivin A receptor, type IB0.088
iqgap1IQ motif containing GTPase activating protein 10.088
zgc:113625zgc:1136250.087
stc1lstanniocalcin 1, like0.087
sb:cb730sb:cb7300.087
nebnebulin0.087
cfl2lcofilin 2, like0.085
pvrl1bpoliovirus receptor-related 1b0.085
smyhc1slow myosin heavy chain 10.084
s100tS100 calcium binding protein T0.084
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.083
nrarpanotch-regulated ankyrin repeat protein a0.083
acsl4aacyl-CoA synthetase long-chain family member 4a0.083
ptgs2aprostaglandin-endoperoxide synthase 2a0.082
hspd1heat shock 60kD protein 1 (chaperonin)0.081
lingo1bleucine rich repeat and Ig domain containing 1b0.081
acvr2aactivin receptor IIa0.081
cmlc1cardiac myosin light chain-10.081
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.080
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.080
casq2calsequestrin 20.080
zgc:55259zgc:552590.079
slmapbsarcolemma associated protein b0.079
dnaja1lDnaJ (Hsp40) homolog, subfamily A, member 1, like0.079
mylz2myosin, light polypeptide 2, skeletal muscle0.078
gngt2bguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b0.078
zgc:56466zgc:564660.078
tpm1tropomyosin 1 (alpha)0.078
mat2amethionine adenosyltransferase II, alpha0.078
tnnt2atroponin T2a, cardiac0.077
rps6ka3aribosomal protein S6 kinase, polypeptide 3a0.077
cnn2calponin 20.077
rab1aRAB1A, member RAS oncogene family0.076
tgif1TGFB-induced factor homeobox 10.076
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.075
ttyh2ltweety homolog 2, like0.075
adrb3aadrenergic receptor, beta 3a0.074
gria4bglutamate receptor, ionotropic, AMPA 4b0.073
rhoubras homolog gene family, member Ub0.073
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.682
PknProtein kinase related to protein kinase N0.361
nwknervous wreck0.276
CG8155CG8155 gene product from transcript CG8155-RA0.271
WnkCG7177 gene product from transcript CG7177-RA0.262
trioCG18214 gene product from transcript CG18214-RA0.254
RhebCG1081 gene product from transcript CG1081-RA0.245
Pk61CProtein kinase 61C0.241
pucpuckered0.240
cnocanoe0.234
stgstring0.223
Fak56DFocal Adhesion Kinase0.212
NaCP60ENa channel protein 60E0.206
CG6509CG6509 gene product from transcript CG6509-RB0.205
saxsaxophone0.191
wupAwings up A0.189
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.178
shotshort stop0.165
rokRho-kinase0.164
drkdownstream of receptor kinase0.164
Prp31CG6876 gene product from transcript CG6876-RA0.151
Stat92ESignal-transducer and activator of transcription protein at 92E0.145
KhcKinesin heavy chain0.141
mbcmyoblast city0.139
gekgenghis khan0.132
cenG1Acentaurin gamma 1A0.117
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.117
Su(H)Suppressor of Hairless0.115
ninaCneither inactivation nor afterpotential C0.106
GugGrunge0.105
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.102
DabDisabled0.102
CycACyclin A0.102
MadMothers against dpp0.102
CG7158CG7158 gene product from transcript CG7158-RA0.101
HemHEM-protein0.101
CG3573CG3573 gene product from transcript CG3573-RA0.091
l(2)k16918lethal (2) k169180.091
ari-2ariadne 20.090
flwflapwing0.090
PtenCG5671 gene product from transcript CG5671-RB0.090
synjsynaptojanin0.088
unc-104CG8566 gene product from transcript CG8566-RB0.087
SosSon of sevenless0.084
PakPAK-kinase0.078
dosdaughter of sevenless0.078
staistathmin0.076
rlrolled0.073
CG8334CG8334 gene product from transcript CG8334-RA0.072
lgslegless0.072
dysdysfusion0.071
rapsrapsynoid0.071
mtsmicrotubule star0.070
Tre1trapped in endoderm-10.068
CG11033CG11033 gene product from transcript CG11033-RB0.067
plexBplexin B0.067
sec6CG5341 gene product from transcript CG5341-RA0.067
mspsmini spindles0.067
yrtyurt0.067
DAAMDishevelled Associated Activator of Morphogenesis0.066
Mkp3Mitogen-activated protein kinase phosphatase 30.065
sizschizo0.064
slssallimus0.063
TorTarget of rapamycin0.062
jumujumeau0.061
maskmultiple ankyrin repeats single KH domain0.061
Hr96Hormone receptor-like in 960.060
Plc21CPhospholipase C at 21C0.059
JraJun-related antigen0.058
bazbazooka0.058
Ank2Ankyrin 20.057
Smg1CG32743 gene product from transcript CG32743-RA0.056
Eip63EEcdysone-induced protein 63E0.055
Tak1TGF-beta activated kinase 10.054
Zn72DCG5215 gene product from transcript CG5215-RB0.053
cpxcomplexin0.052
psidinphagocyte signaling impaired0.051
RalaRas-related protein0.051
Mlp84BMuscle LIM protein at 84B0.051
CG1233CG1233 gene product from transcript CG1233-RB0.051
CakiCalcium/calmodulin-dependent protein kinase0.050
pod1CG4532 gene product from transcript CG4532-RF0.049
NmnatNicotinamide mononucleotide adenylyltransferase0.049
SbfSET domain binding factor0.048
MtlMig-2-like0.047
neurneuralized0.047
SmoxSmad on X0.047
p120ctnAdherens junction protein p1200.046
pydpolychaetoid0.046
Dip3Dorsal interacting protein 30.045
Rtnl1CG33113 gene product from transcript CG33113-RF0.045
CG1021CG1021 gene product from transcript CG1021-RE0.045
G-ialpha65AG protein alphai subunit 65A0.045
Myo31DFMyosin 31DF0.045
CG5798CG5798 gene product from transcript CG5798-RA0.044
neuroliginCG13772 gene product from transcript CG13772-RA0.044
AbiAbelson interacting protein0.044
trptransient receptor potential0.044
Flo-2flotillin 20.043
Rho1CG8416 gene product from transcript CG8416-RB0.043
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.999
PTK2PTK2 protein tyrosine kinase 20.989
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.983
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.975
S100A6S100 calcium binding protein A60.963
DNM2dynamin 20.960
SH3KBP1SH3-domain kinase binding protein 10.952
DNM1dynamin 10.942
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.939
SFNstratifin0.930
ITSN1intersectin 1 (SH3 domain protein)0.929
NCF2neutrophil cytosolic factor 20.913
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.912
MTORmechanistic target of rapamycin (serine/threonine kinase)0.904
FGFR2fibroblast growth factor receptor 20.900
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.890
BCAR1breast cancer anti-estrogen resistance 10.889
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.868
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.865
SNX9sorting nexin 90.863
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.858
ARRB1arrestin, beta 10.850
GRB2growth factor receptor-bound protein 20.849
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.846
TNNC1troponin C type 1 (slow)0.840
ILKintegrin-linked kinase0.832
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.830
GRB7growth factor receptor-bound protein 70.822
RIN3Ras and Rab interactor 30.819
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.790
MDM2Mdm2 p53 binding protein homolog (mouse)0.787
NCKAP1NCK-associated protein 10.777
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.776
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.764
TPM1tropomyosin 1 (alpha)0.753
RHOAras homolog gene family, member A0.750
FGFR1fibroblast growth factor receptor 10.745
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.737
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.724
PLCG1phospholipase C, gamma 10.714
UNC119unc-119 homolog (C. elegans)0.704
S100A8S100 calcium binding protein A80.701
GABARAPL1GABA(A) receptor-associated protein like 10.693
S100A11S100 calcium binding protein A110.684
RASA1RAS p21 protein activator (GTPase activating protein) 10.677
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.676
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.662
ADRBK1adrenergic, beta, receptor kinase 10.648
SEMA4Asema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A0.633
MARK3MAP/microtubule affinity-regulating kinase 30.609
ADAM15ADAM metallopeptidase domain 150.608
ABI1abl-interactor 10.601
HAP1huntingtin-associated protein 10.595
FKBP4FK506 binding protein 4, 59kDa0.592
SKILSKI-like oncogene0.583
CNKSR2connector enhancer of kinase suppressor of Ras 20.582
FOSFBJ murine osteosarcoma viral oncogene homolog0.580
OCRLoculocerebrorenal syndrome of Lowe0.577
TSC2tuberous sclerosis 20.561
EGFRepidermal growth factor receptor0.561
ANKRD28ankyrin repeat domain 280.553
SH3RF1SH3 domain containing ring finger 10.541
TBCDtubulin folding cofactor D0.536
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.532
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.530
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.529
PSEN1presenilin 10.528
TRAF5TNF receptor-associated factor 50.526
HTThuntingtin0.521
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.514
GSK3Bglycogen synthase kinase 3 beta0.510
JUNjun proto-oncogene0.507
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.505
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.486
TFGTRK-fused gene0.483
S100BS100 calcium binding protein B0.481
ZMYND11zinc finger, MYND-type containing 110.468
FMNL1formin-like 10.466
CCR5chemokine (C-C motif) receptor 50.462
C19orf50chromosome 19 open reading frame 500.452
AKT1v-akt murine thymoma viral oncogene homolog 10.451
MPRIPmyosin phosphatase Rho interacting protein0.447
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.443
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.440
ARL2ADP-ribosylation factor-like 20.438
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.436
MYCBP2MYC binding protein 20.429
THOC4THO complex 40.426
RHEBRas homolog enriched in brain0.425
RAB5ARAB5A, member RAS oncogene family0.418
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.418
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.417
BCRbreakpoint cluster region0.407
TJP2tight junction protein 2 (zona occludens 2)0.406
TOR1Atorsin family 1, member A (torsin A)0.405
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.403
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.395
RICTORRPTOR independent companion of MTOR, complex 20.390
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.389
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.381
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ephb2Eph receptor B20.984
Efnb2ephrin B20.981
Epha4Eph receptor A40.977
BrafBraf transforming gene0.914
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.911
Nf1neurofibromatosis 10.893
Rac1RAS-related C3 botulinum substrate 10.881
Klklotho0.875
Ilkintegrin linked kinase0.855
Itsn1intersectin 1 (SH3 domain protein 1A)0.842
Sox10SRY-box containing gene 100.833
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.829
Retret proto-oncogene0.797
Plxna1plexin A10.775
Arrb2arrestin, beta 20.763
Mtormechanistic target of rapamycin (serine/threonine kinase)0.749
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.736
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.720
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.699
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.693
Lrrk2leucine-rich repeat kinase 20.693
Adrb1adrenergic receptor, beta 10.693
Plxnb1plexin B10.618
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.615
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.615
Adrbk1adrenergic receptor kinase, beta 10.614
Chrm1cholinergic receptor, muscarinic 1, CNS0.613
Wnt5awingless-related MMTV integration site 5A0.606
Prkceprotein kinase C, epsilon0.596
Ctnnb1catenin (cadherin associated protein), beta 10.584
Ptk2bPTK2 protein tyrosine kinase 2 beta0.572
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.569
Ntf3neurotrophin 30.563
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.563
Vav1vav 1 oncogene0.542
Spry4sprouty homolog 4 (Drosophila)0.535
Dlg4discs, large homolog 4 (Drosophila)0.531
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.529
Ldb3LIM domain binding 30.516
Leprleptin receptor0.505
Srsf9serine/arginine-rich splicing factor 90.503
Dock1dedicator of cytokinesis 10.502
RictorRPTOR independent companion of MTOR, complex 20.497
Bcl2B-cell leukemia/lymphoma 20.484
Wnt7awingless-related MMTV integration site 7A0.462
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.446
Arpc4actin related protein 2/3 complex, subunit 40.441
Banf1barrier to autointegration factor 10.438
Grb2growth factor receptor bound protein 20.437
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.421
Hrchistidine rich calcium binding protein0.417
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.409
Sh3bp1SH3-domain binding protein 10.408
Mkl1MKL (megakaryoblastic leukemia)/myocardin-like 10.399
Epha1Eph receptor A10.399
Ccr2chemokine (C-C motif) receptor 20.398
Npy2rneuropeptide Y receptor Y20.396
Pnpla2patatin-like phospholipase domain containing 20.382
Rasgrp2RAS, guanyl releasing protein 20.381
Prkccprotein kinase C, gamma0.375
Epb4.1l2erythrocyte protein band 4.1-like 20.374
Selplgselectin, platelet (p-selectin) ligand0.370
Kifc2kinesin family member C20.363
Git1G protein-coupled receptor kinase-interactor 10.349
Shc3src homology 2 domain-containing transforming protein C30.348
Hdac7histone deacetylase 70.344
Wdr1WD repeat domain 10.343
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.342
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.340
Erhenhancer of rudimentary homolog (Drosophila)0.338
SrcRous sarcoma oncogene0.334
Spna2spectrin alpha 20.333
Arrb1arrestin, beta 10.330
Wipf1WAS/WASL interacting protein family, member 10.327
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.319
Scn5asodium channel, voltage-gated, type V, alpha0.318
Ptpn13protein tyrosine phosphatase, non-receptor type 130.314
Mapkap1mitogen-activated protein kinase associated protein 10.312
Cdh6cadherin 60.311
Drd2dopamine receptor D20.310
Vdrvitamin D receptor0.308
Tnni2troponin I, skeletal, fast 20.304
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.303
Tnnt3troponin T3, skeletal, fast0.301
Kalrnkalirin, RhoGEF kinase0.297
Syn2synapsin II0.289
Vaspvasodilator-stimulated phosphoprotein0.288
Hmha1histocompatibility (minor) HA-10.286
Efna1ephrin A10.280
Pxnpaxillin0.273
Cnr1cannabinoid receptor 1 (brain)0.269
Nrbp2nuclear receptor binding protein 20.266
Magi1membrane associated guanylate kinase, WW and PDZ domain containing 10.262
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.261
Stim2stromal interaction molecule 20.259
Ly6hlymphocyte antigen 6 complex, locus H0.258
Adam11a disintegrin and metallopeptidase domain 110.257
Ltblymphotoxin B0.255
Mtap2microtubule-associated protein 20.254
Rtknrhotekin0.247
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Taglntransgelin0.846
Acta2smooth muscle alpha-actin0.562
Myl9myosin, light chain 9, regulatory0.480
Pja2praja 2, RING-H2 motif containing0.316
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.303
Hk1hexokinase 10.298
Homer1homer homolog 1 (Drosophila)0.244
Anxa2annexin A20.235
Actg2actin, gamma 2, smooth muscle, enteric0.166
Sptan1spectrin, alpha, non-erythrocytic 10.152
Dapk3death-associated protein kinase 30.151
Amphamphiphysin0.144
Gng7guanine nucleotide binding protein (G protein), gamma 70.133
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.127
Cnksr2connector enhancer of kinase suppressor of Ras 20.126
Epas1endothelial PAS domain protein 10.111
Flnafilamin A, alpha0.110
Gria2glutamate receptor, ionotropic, AMPA 20.109
Prkchprotein kinase C, eta0.098
Cfpcomplement factor properdin0.097
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.096
Shank2SH3 and multiple ankyrin repeat domains 20.094
Ola1Obg-like ATPase 10.093
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.092
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.090
Stxbp5syntaxin binding protein 5 (tomosyn)0.090
Sstr1somatostatin receptor 10.084
Picalmphosphatidylinositol binding clathrin assembly protein0.081
Adora2aadenosine A2a receptor0.081
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.081
Csrp1cysteine and glycine-rich protein 10.080
A1i3alpha-1-inhibitor III0.079
Camk4calcium/calmodulin-dependent protein kinase IV0.078
Gipc1GIPC PDZ domain containing family, member 10.074
Sdc3syndecan 30.073
Tgfbr2transforming growth factor, beta receptor II0.071
Pum1pumilio homolog 1 (Drosophila)0.070
Mcammelanoma cell adhesion molecule0.069
Accn1amiloride-sensitive cation channel 1, neuronal0.069
Ephb1Eph receptor B10.067
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.066
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.066
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.066
Syn1synapsin I0.066
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.066
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.065
Lpcat4lysophosphatidylcholine acyltransferase 40.065
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.064
Rab3il1RAB3A interacting protein (rabin3)-like 10.064
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.063
Fgfr1Fibroblast growth factor receptor 10.063
Scn3bsodium channel, voltage-gated, type III, beta0.062
Dnm1dynamin 10.061
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.061
Sel1lsel-1 suppressor of lin-12-like (C. elegans)0.061
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.061
Trappc2trafficking protein particle complex 20.059
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.059
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.058
Sh3gl2SH3-domain GRB2-like 20.057
Myh7myosin, heavy chain 7, cardiac muscle, beta0.056
Nckap1NCK-associated protein 10.056
Ryr2ryanodine receptor 2, cardiac0.055
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.054
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.054
Vav1vav 1 guanine nucleotide exchange factor0.053
Syt7synaptotagmin VII0.053
Pfn1profilin 10.053
Clcn2chloride channel 20.053
Gucy1b3guanylate cyclase 1, soluble, beta 30.053
Syt4synaptotagmin IV0.053
Flnbfilamin, beta0.053
Lin7blin-7 homolog b (C. elegans)0.053
Chrm1cholinergic receptor, muscarinic 10.052
Btg1B-cell translocation gene 1, anti-proliferative0.052
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.052
Myo1cmyosin IC0.052
Pls3plastin 3 (T-isoform)0.051
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.051
Pi4kaphosphatidylinositol 4-kinase, catalytic, alpha0.051
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.050
Gria1glutamate receptor, ionotropic, AMPA 10.050
Snap25synaptosomal-associated protein 250.050
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.050
Jak2Janus kinase 20.049
N5DNA binding protein N50.049
Cckcholecystokinin0.049
Lcp2lymphocyte cytosolic protein 20.048
Vsnl1visinin-like 10.048
Fam108a1family with sequence similarity 108, member A10.048
Sept10septin 100.048
Robo2roundabout homolog 2 (Drosophila)0.047
Dync1h1dynein cytoplasmic 1 heavy chain 10.047
Vamp3vesicle-associated membrane protein 30.047
Tpm2tropomyosin 2, beta0.046
Chrm3cholinergic receptor, muscarinic 30.046
Cdk5cyclin-dependent kinase 50.046
Dgkzdiacylglycerol kinase zeta0.046
Rhoaras homolog gene family, member A0.046
SvopSV2 related protein0.046