The network for 'regulation of leukocyte chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte chemotaxis

Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cdh5cadherin 50.069
csf1racolony stimulating factor 1 receptor, a0.041
tie2endothelium-specific receptor tyrosine kinase 20.037
plxnd1plexin D10.029
kdrlkinase insert domain receptor like0.025
myf5myogenic factor 50.024
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.021
sox10SRY-box containing gene 100.020
tie1endothelium-specific receptor tyrosine kinase 10.019
vegfcvascular endothelial growth factor c0.017
dll4delta-like 4 (Drosophila)0.016
nod1nucleotide-binding oligomerization domain containing 10.016
dzip1DAZ interacting protein 10.016
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.014
etv2ets variant gene 20.014
jam2ajunctional adhesion molecule 2a0.014
nrp2bneuropilin 2b0.014
osr1odd-skipped related 1 (Drosophila)0.013
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.013
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.013
spns2spinster homolog 2 (Drosophila)0.012
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.012
LOC557072caspase recruitment domain-containing protein 11-like0.011
s1pr2sphingosine-1-phosphate receptor 20.010
slc30a7solute carrier family 30 (zinc transporter), member 70.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CCR5chemokine (C-C motif) receptor 51.000
FYNFYN oncogene related to SRC, FGR, YES0.995
CXCL9chemokine (C-X-C motif) ligand 90.995
CCL5chemokine (C-C motif) ligand 50.986
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.977
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.975
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.970
CCL4chemokine (C-C motif) ligand 40.929
CXCL10chemokine (C-X-C motif) ligand 100.925
S100BS100 calcium binding protein B0.909
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.889
CCR7chemokine (C-C motif) receptor 70.883
CCL19chemokine (C-C motif) ligand 190.880
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.878
IFNGinterferon, gamma0.862
CCL22chemokine (C-C motif) ligand 220.855
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.852
S100A1S100 calcium binding protein A10.848
VEGFAvascular endothelial growth factor A0.830
AXLAXL receptor tyrosine kinase0.828
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.810
S100A16S100 calcium binding protein A160.809
CD2CD2 molecule0.785
NRP1neuropilin 10.784
S100A14S100 calcium binding protein A140.776
DPP4dipeptidyl-peptidase 40.757
IL8interleukin 80.755
CXCL11chemokine (C-X-C motif) ligand 110.736
FN1fibronectin 10.707
CCL8chemokine (C-C motif) ligand 80.691
CCL2chemokine (C-C motif) ligand 20.686
PDIA3protein disulfide isomerase family A, member 30.684
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.629
CXCL13chemokine (C-X-C motif) ligand 130.628
CXCR4chemokine (C-X-C motif) receptor 40.614
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.567
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.559
PLAURplasminogen activator, urokinase receptor0.558
CCL13chemokine (C-C motif) ligand 130.557
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.551
ABI2abl-interactor 20.534
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.520
PLATplasminogen activator, tissue0.515
CCR1chemokine (C-C motif) receptor 10.487
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.484
COL1A1collagen, type I, alpha 10.463
S100A6S100 calcium binding protein A60.446
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.424
IL2RGinterleukin 2 receptor, gamma0.411
IL10interleukin 100.407
IL2RBinterleukin 2 receptor, beta0.401
IL6interleukin 6 (interferon, beta 2)0.391
FYBFYN binding protein0.371
CXCL2chemokine (C-X-C motif) ligand 20.364
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.354
CCR2chemokine (C-C motif) receptor 20.346
ADAM9ADAM metallopeptidase domain 90.342
CCL11chemokine (C-C motif) ligand 110.321
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.319
PLAUplasminogen activator, urokinase0.315
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.298
IL7Rinterleukin 7 receptor0.297
CCL7chemokine (C-C motif) ligand 70.282
CCR4chemokine (C-C motif) receptor 40.274
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.256
VCAM1vascular cell adhesion molecule 10.252
NCF1neutrophil cytosolic factor 10.250
NCF2neutrophil cytosolic factor 20.248
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.243
COL4A1collagen, type IV, alpha 10.234
COL5A1collagen, type V, alpha 10.231
CCL3chemokine (C-C motif) ligand 30.230
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.228
SNX33sorting nexin 330.205
THBS1thrombospondin 10.205
MMP12matrix metallopeptidase 12 (macrophage elastase)0.193
CXCL3chemokine (C-X-C motif) ligand 30.191
APOEapolipoprotein E0.190
S100A9S100 calcium binding protein A90.188
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.182
PACSIN3protein kinase C and casein kinase substrate in neurons 30.179
JAM2junctional adhesion molecule 20.170
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.166
CXCR6chemokine (C-X-C motif) receptor 60.159
RGS1regulator of G-protein signaling 10.152
LTBP2latent transforming growth factor beta binding protein 20.152
CCL20chemokine (C-C motif) ligand 200.151
IRF4interferon regulatory factor 40.150
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.150
FPR3formyl peptide receptor 30.146
BCL2A1BCL2-related protein A10.146
COL4A2collagen, type IV, alpha 20.144
C2complement component 20.144
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.141
IGFBP5insulin-like growth factor binding protein 50.141
COL1A2collagen, type I, alpha 20.140
COL3A1collagen, type III, alpha 10.137
TNFtumor necrosis factor0.136
TSC22D4TSC22 domain family, member 40.134
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cxcl10chemokine (C-X-C motif) ligand 100.859
Ctsscathepsin S0.750
Ccl2chemokine (C-C motif) ligand 20.738
Il1binterleukin 1 beta0.543
Cxcl2chemokine (C-X-C motif) ligand 20.506
Ccl4chemokine (C-C motif) ligand 40.454
Il6interleukin 60.440
Cd14CD14 molecule0.302
RT1-BaRT1 class II, locus Ba0.276
TyrobpTyro protein tyrosine kinase binding protein0.234
Il1ainterleukin 1 alpha0.223
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.170
Ccl3chemokine (C-C motif) ligand 30.168
RT1-Db1RT1 class II, locus Db10.122
Hckhemopoietic cell kinase0.122
Ccl20chemokine (C-C motif) ligand 200.097
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.094
Fcn1ficolin (collagen/fibrinogen domain containing) 10.085
Lyz2lysozyme 20.076
Ccl7chemokine (C-C motif) ligand 70.072
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.068
Tnftumor necrosis factor (TNF superfamily, member 2)0.068
Fosl1fos-like antigen 10.064
Fgfr2fibroblast growth factor receptor 20.063
Cd68Cd68 molecule0.055
Nek9NIMA (never in mitosis gene a)- related kinase 90.050
Cd53Cd53 molecule0.046
Ier3immediate early response 30.045
Igsf6immunoglobulin superfamily, member 60.041
Ptger4prostaglandin E receptor 4 (subtype EP4)0.038
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.036
TcrbT-cell receptor beta chain0.035
RT1-DaRT1 class II, locus Da0.034
Dio2deiodinase, iodothyronine, type II0.033
Olr1500olfactory receptor 15000.033
Edn1endothelin 10.032
Il2rginterleukin 2 receptor, gamma0.032
Cd83CD83 molecule0.030
Tgm1transglutaminase 1, K polypeptide0.030
Ccr2chemokine (C-C motif) receptor 20.029
C5ar1complement component 5a receptor 10.028
Sellselectin L0.026
F2rl1coagulation factor II (thrombin) receptor-like 10.025
Il2rbinterleukin 2 receptor, beta0.025
Il8rbinterleukin 8 receptor, beta0.025
Icam1intercellular adhesion molecule 10.025
Ccr5chemokine (C-C motif) receptor 50.025
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.023
Rab20RAB20, member RAS oncogene family0.023
Ptgs2prostaglandin-endoperoxide synthase 20.023
Gzmkgranzyme K0.023
Socs3suppressor of cytokine signaling 30.023
Laptm5lysosomal protein transmembrane 50.022
Cpa3carboxypeptidase A3, mast cell0.022
Igfbp5insulin-like growth factor binding protein 50.021
Klrd1killer cell lectin-like receptor, subfamily D, member 10.021
Rgs1regulator of G-protein signaling 10.020
Neurl3neuralized homolog 3 (Drosophila)0.020
Il1rninterleukin 1 receptor antagonist0.019
Cd86CD86 molecule0.019
Mmp3matrix metallopeptidase 30.018
C1qccomplement component 1, q subcomponent, C chain0.018
Gzmbgranzyme B0.018
Calcrlcalcitonin receptor-like0.018
Seleselectin E0.018
Plauplasminogen activator, urokinase0.018
Cd37CD37 molecule0.017
Nkg7natural killer cell group 7 sequence0.017
Ccr3chemokine (C-C motif) receptor 30.017
Iappislet amyloid polypeptide0.017
Adam2ADAM metallopeptidase domain 20.016
Reg3gregenerating islet-derived 3 gamma0.016
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.016
Gpr83G protein-coupled receptor 830.016
Cxcl11chemokine (C-X-C motif) ligand 110.016
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.015
Syn1synapsin I0.015
Rhojras homolog gene family, member J0.015
P2ry14purinergic receptor P2Y, G-protein coupled, 140.015
Cd4Cd4 molecule0.015
Xcl1chemokine (C motif) ligand 10.015
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.015
F2rl2coagulation factor II (thrombin) receptor-like 20.014
Ptprcprotein tyrosine phosphatase, receptor type, C0.014
Tfpi2tissue factor pathway inhibitor 20.014
C1qacomplement component 1, q subcomponent, A chain0.014
Lst1leukocyte specific transcript 10.014
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.013
Cd69Cd69 molecule0.013
Sftpa1surfactant protein A10.013
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.013
Ifit3interferon-induced protein with tetratricopeptide repeats 30.013
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.013
Mapk1mitogen activated protein kinase 10.013
Ptpn12protein tyrosine phosphatase, non-receptor type 120.012
Mmp12matrix metallopeptidase 120.012
Cd200r1CD200 receptor 10.012
Prkcgprotein kinase C, gamma0.012