The network for 'ubiquitin dependent protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

NameDescriptionProbabilityFunc Analog Organism
CDC48Cdc48p1.000
RPT1Rpt1p0.999
RPT6Rpt6p0.999
KAR2Kar2p0.998
SKP1Skp1p0.996
RAD23Rad23p0.993
UBP6Ubp6p0.988
RPN10Rpn10p0.983
RPT4Rpt4p0.982
PRE1Pre1p0.982
UFD4Ufd4p0.974
SEM1Sem1p0.973
RPT3Rpt3p0.967
PRE5Pre5p0.964
RPT2Rpt2p0.964
PPH22Pph22p0.958
RPN9Rpn9p0.956
MAD2Mad2p0.955
APC5Apc5p0.954
CDC53Cdc53p0.947
SCJ1Scj1p0.943
MUB1Mub1p0.940
RPN12Rpn12p0.934
PRE10Pre10p0.933
ECM29Ecm29p0.932
PRE2Pre2p0.922
UBX2Ubx2p0.917
MND2Mnd2p0.915
RPN6Rpn6p0.913
PRE9Pre9p0.902
PRE4Pre4p0.887
RPT5Rpt5p0.884
CDC23Cdc23p0.869
PUP2Pup2p0.862
UFD2Ufd2p0.862
DOC1Doc1p0.857
UBR1Ubr1p0.848
VPS36Vps36p0.844
UMP1Ump1p0.843
UFD1Ufd1p0.836
RPN3Rpn3p0.830
RPN11Rpn11p0.825
APC2Apc2p0.825
FYV10Fyv10p0.824
DSK2Dsk2p0.820
VPS60Vps60p0.815
PRE6Pre6p0.814
NPL4Npl4p0.804
CDC27Cdc27p0.800
VID30Vid30p0.795
TRE1Tre1p0.768
DER1Der1p0.767
CDC16Cdc16p0.767
SWM1Swm1p0.763
PRE7Pre7p0.748
OTU1Otu1p0.744
CDC4Cdc4p0.739
RPN7Rpn7p0.734
CDC31Cdc31p0.724
RPN8Rpn8p0.723
CDC20Cdc20p0.708
HSM3Hsm3p0.693
CUR1Cur1p0.680
BRE5Bre5p0.664
RKR1Rkr1p0.663
MET30Met30p0.658
PUP1Pup1p0.656
CDC26Cdc26p0.649
UBC4Ubc4p0.648
GID7Gid7p0.646
DFM1Dfm1p0.642
SCL1Scl1p0.639
CTF13Ctf13p0.608
UBX7Ubx7p0.602
HRT1Hrt1p0.600
PUP3Pup3p0.597
HRD3Hrd3p0.586
APC4Apc4p0.571
SSE2Sse2p0.570
YPI1Ypi1p0.563
PRE3Pre3p0.560
RPN2Rpn2p0.557
RPN1Rpn1p0.547
DDI1Ddi1p0.547
RPN13Rpn13p0.546
ELC1Elc1p0.535
UBC13Ubc13p0.531
GRR1Grr1p0.524
RPN4Rpn4p0.524
HRD1Hrd1p0.520
DMA1Dma1p0.514
PMT1Pmt1p0.514
CUE1Cue1p0.512
MTW1Mtw1p0.502
YOS9Yos9p0.497
KSP1Ksp1p0.490
GPB2Gpb2p0.484
FES1Fes1p0.482
APC1Apc1p0.470
APP1App1p0.466
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rpn-7Protein RPN-70.896
rpn-12Protein RPN-120.847
rpt-5Protein RPT-50.705
rpt-3Protein RPT-30.681
pas-2Protein PAS-20.674
pas-4Protein PAS-40.642
rpt-2Protein RPT-20.630
npl-4.2Protein NPL-4.20.626
rpn-6.1Protein RPN-6.10.615
rpn-3Protein RPN-30.595
npl-4.1Protein NPL-4.10.499
rpn-2Protein RPN-20.499
pas-1Protein PAS-10.466
pbs-6Protein PBS-60.447
rpt-4Protein RPT-40.433
atx-3Protein ATX-30.431
rpn-11Protein RPN-110.360
rnr-1Protein RNR-10.335
pbs-2Protein PBS-20.332
pbs-5Protein PBS-50.312
hgrs-1Protein HGRS-10.290
tba-2Protein TBA-20.285
app-1Protein APP-10.227
pas-6Protein PAS-60.210
E04D5.1Protein E04D5.10.205
pbs-3Protein PBS-30.196
rpn-9Protein RPN-90.189
pbs-1Protein PBS-10.184
sas-5Protein SAS-50.180
rpa-1Protein RPA-10.168
usp-46Protein USP-460.151
pbs-7Protein PBS-70.122
pas-5Protein PAS-50.122
pas-7Protein PAS-70.122
kle-2Protein KLE-20.117
Y71H2AM.20Protein Y71H2AM.200.117
skr-1Protein SKR-10.116
usp-14Protein USP-140.109
mom-2Protein MOM-20.107
T20B12.7Protein T20B12.70.103
ubc-25Protein UBC-250.098
pbs-4Protein PBS-40.098
F56D12.6Protein F56D12.60.098
mig-5Protein MIG-50.097
zen-4Protein ZEN-40.096
pcn-1Protein PCN-10.093
rpn-10Protein RPN-100.092
K08E3.5Protein K08E3.50.090
bub-1Protein BUB-10.088
rpn-5Protein RPN-50.084
atg-18Protein ATG-180.084
T22F3.2Protein T22F3.20.083
hcp-1Protein HCP-10.082
his-45Protein HIS-450.082
egl-18Protein EGL-180.081
ZK507.6Protein ZK507.60.080
smk-1Protein SMK-10.076
F46F11.6Protein F46F11.60.074
stam-1Protein STAM-10.074
gpr-1Protein GPR-10.072
cul-1Protein CUL-10.072
tag-353Protein TAG-3530.068
syx-5Protein SYX-50.065
ykt-6Protein YKT-60.064
syx-17Protein SYX-170.064
cdc-48.2Protein CDC-48.20.063
ZK1055.7Protein ZK1055.70.062
CELE_C25A1.4Protein C25A1.40.062
CELE_R102.5Protein R102.50.061
bmk-1Protein BMK-10.060
hda-1Protein HDA-10.060
rpt-1Protein RPT-10.059
sec-12Protein SEC-120.059
rpt-6Protein RPT-60.059
ubxn-4Protein UBXN-40.059
dpy-30Protein DPY-300.058
miro-1Protein MIRO-10.058
K02B2.1Protein K02B2.10.057
imb-2Protein IMB-20.055
CELE_T10C6.6Protein T10C6.60.055
csn-3Protein CSN-30.054
mat-3Protein MAT-30.054
taf-5Protein TAF-50.054
lin-23Protein LIN-230.053
pup-2Protein PUP-20.053
W09D10.1Protein W09D10.10.052
rod-1Protein ROD-10.052
gyg-2Protein GYG-20.052
T01G9.2Protein T01G9.20.051
tbb-1Protein TBB-10.051
prp-31Protein PRP-310.051
vpr-1Protein VPR-10.051
asb-1Protein ASB-10.050
gei-11Protein GEI-110.050
vps-53Protein VPS-530.049
ceh-38Protein CEH-380.049
ZK809.5Protein ZK809.50.049
lin-3Protein LIN-30.049
rab-6.1Protein RAB-6.10.049
par-5Protein PAR-50.048
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.974
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.935
psmb1proteasome (prosome, macropain) subunit, beta type, 10.929
zgc:92775zgc:927750.916
psmb7proteasome (prosome, macropain) subunit, beta type, 70.911
psma8proteasome (prosome, macropain) subunit, alpha type, 80.875
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.782
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.775
psmb3proteasome (prosome, macropain) subunit, beta type, 30.745
vcpvalosin containing protein0.742
psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.742
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.719
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.712
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.684
psmb2proteasome (prosome, macropain) subunit, beta type, 20.681
psmb5proteasome (prosome, macropain) subunit, beta type, 50.676
ccnb1cyclin B10.653
usp5ubiquitin specific protease 50.630
ck2bcasein kinase 2 beta0.598
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.595
psma1proteasome (prosome, macropain) subunit, alpha type, 10.550
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.547
kif23kinesin family member 230.513
bc2putative breast adenocarcinoma marker0.509
supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.506
hyou1hypoxia up-regulated 10.496
evx1even-skipped homeobox 10.495
wnt4awingless-type MMTV integration site family, member 4a0.481
aurkbaurora kinase B0.474
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.474
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.463
arf2ADP-ribosylation factor 20.460
baxabcl2-associated X protein, a0.457
adrm1badhesion regulating molecule 1b0.444
psmb6proteasome (prosome, macropain) subunit, beta type, 60.418
rab1aRAB1A, member RAS oncogene family0.416
hspa4bheat shock protein 4b0.412
chukconserved helix-loop-helix ubiquitous kinase0.412
cdc20cell division cycle 20 homolog0.399
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.397
tmed2transmembrane emp24 domain trafficking protein 20.365
zgc:123326zgc:1233260.362
plk1polo-like kinase 1 (Drosophila)0.362
zgc:86903zgc:869030.357
maxmyc-associated factor X0.355
sirt1sirtuin (silent mating type information regulation 2 homolog) 10.340
cnot6CCR4-NOT transcription complex, subunit 60.333
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.306
btg2B-cell translocation gene 20.305
syvn1synovial apoptosis inhibitor 1, synoviolin0.296
zgc:153910zgc:1539100.295
zgc:55448zgc:554480.293
si:ch211-69g19.2si:ch211-69g19.20.291
psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.288
psmb4proteasome (prosome, macropain) subunit, beta type, 40.288
ccna2cyclin A20.282
psma4proteasome (prosome, macropain) subunit, alpha type, 40.279
zgc:110116zgc:1101160.275
nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.271
ubinataxin-1 ubiquitin-like interacting protein0.271
lancl1LanC antibiotic synthetase component C-like 1 (bacterial)0.270
si:ch211-239j15.4si:ch211-239j15.40.268
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.268
ube2g2ubiquitin-conjugating enzyme E2G 20.267
csnk1dbcasein kinase 1, delta b0.265
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.263
eif1beukaryotic translation initiation factor 1B0.257
ccnb2cyclin B20.256
dnm1ldynamin 1-like0.254
fliiflightless I homolog (Drosophila)0.253
rqcd1RCD1 required for cell differentiation1 homolog (S. pombe)0.251
kpna4karyopherin alpha 4 (importin alpha 3)0.251
faf2Fas associated factor family member 20.251
psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.248
srsf11serine/arginine-rich splicing factor 110.248
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.246
gdi2GDP dissociation inhibitor 20.244
suv39h1bsuppressor of variegation 3-9 homolog 1b0.240
tia1lcytotoxic granule-associated RNA binding protein 1, like0.234
trim55btripartite motif-containing 55b0.234
capn2bcalpain 2, (m/II) large subunit b0.231
gins3GINS complex subunit 30.213
zgc:174506zgc:1745060.213
psmd11aproteasome (prosome, macropain) 216S subunit, non-ATPase, 11a0.212
nexnnexilin (F actin binding protein)0.211
cnot8CCR4-NOT transcription complex, subunit 80.208
fbxw11aF-box and WD-40 domain protein 11a0.208
smndc1survival motor neuron domain containing 10.207
psmd11bproteasome (prosome, macropain) 216S subunit, non-ATPase, 11b0.205
foxb1.2forkhead box B1.20.203
lama4laminin, alpha 40.203
cdt1chromatin licensing and DNA replication factor 10.203
ciapin1cytokine induced apoptosis inhibitor 10.199
zgc:56200zgc:562000.199
birc5abaculoviral IAP repeat-containing 5a0.199
atxn2lataxin 2-like0.199
pxnpaxillin0.199
arpp19acAMP-regulated phosphoprotein 19a0.197
zgc:103652zgc:1036520.195
srsf1aserine/arginine-rich splicing factor 1a0.194
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pros29Proteasome 29kD subunit0.965
Prosbeta2Proteasome beta2 subunit0.939
CycBCyclin B0.935
tefutelomere fusion0.887
Prosbeta3Proteasome beta3 subunit0.871
CG13349CG13349 gene product from transcript CG13349-RA0.845
brmbrahma0.840
Mov34CG3416 gene product from transcript CG3416-RA0.778
Ras85DRas oncogene at 85D0.757
Rpt1CG1341 gene product from transcript CG1341-RA0.706
Rpt4CG3455 gene product from transcript CG3455-RA0.694
Rpt3CG16916 gene product from transcript CG16916-RA0.677
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.661
CycECyclin E0.585
CSN5COP9 complex homolog subunit 50.574
Rpn6Proteasome p44.5 subunit0.545
ncdnon-claret disjunctional0.541
Pros35Proteasome 35kD subunit0.538
CG9772CG9772 gene product from transcript CG9772-RB0.535
poloCG12306 gene product from transcript CG12306-RA0.534
Prosbeta1Proteasome beta1 subunit0.534
hpohippo0.529
lqfliquid facets0.514
Vap-33-1CG5014 gene product from transcript CG5014-RB0.501
dcodiscs overgrown0.499
Rpn2CG11888 gene product from transcript CG11888-RA0.487
smosmoothened0.480
Pros26Proteasome 26kD subunit0.476
Rpn1CG7762 gene product from transcript CG7762-RA0.471
Rpn9CG10230 gene product from transcript CG10230-RB0.464
Uba1Ubiquitin activating enzyme 10.426
krzkurtz0.422
barrbarren0.415
Pros54Proteasome 54kD subunit0.413
Vps25Vacuolar protein sorting 250.384
Rpn7CG5378 gene product from transcript CG5378-RA0.372
SaraSmad anchor for receptor activation0.346
lin19lin-19-like0.337
cdc23CG2508 gene product from transcript CG2508-RA0.317
Cul-5Cullin-50.315
CSN3COP9 complex homolog subunit 30.313
Cap-GCG34438 gene product from transcript CG34438-RF0.302
UbcD2Ubiquitin conjugating enzyme 20.301
CG12321CG12321 gene product from transcript CG12321-RA0.282
Rpn5CG1100 gene product from transcript CG1100-RA0.274
Akt1CG4006 gene product from transcript CG4006-RA0.273
mspsmini spindles0.271
mtsmicrotubule star0.271
wdbwiderborst0.263
jubAjuba LIM protein0.258
swmsecond mitotic wave missing0.250
Tak1TGF-beta activated kinase 10.246
Top1Topoisomerase 10.246
SceSex combs extra0.239
Fcp1CG12252 gene product from transcript CG12252-RA0.237
Pros28.1Proteasome 28kD subunit 10.235
miltmilton0.233
cactcactus0.231
CycDCyclin D0.229
RhoGEF2CG9635 gene product from transcript CG9635-RF0.228
Rpn3Regulatory particle non-ATPase 30.228
skpACG16983 gene product from transcript CG16983-RD0.223
CG32581CG32581 gene product from transcript CG32581-RB0.223
Fs(2)KetFemale sterile (2) Ketel0.210
Cul-4Cullin-40.208
bratbrain tumor0.206
Hsp83Heat shock protein 830.205
IncenpInner centromere protein0.203
CG17331CG17331 gene product from transcript CG17331-RA0.197
Prosalpha5Proteasome alpha5 subunit0.197
effeffete0.192
DoaDarkener of apricot0.186
Vps28Vacuolar protein sorting 280.186
Prp8pre-mRNA processing factor 80.186
Rab1Rab-protein 10.173
dikdiskette0.172
CSN6COP9 complex homolog subunit 60.171
dshdishevelled0.167
slmbsupernumerary limbs0.166
fzyfizzy0.165
Rpn11CG18174 gene product from transcript CG18174-RA0.162
CG8979CG8979 gene product from transcript CG8979-RC0.159
egreiger0.151
oskoskar0.150
stepsteppke0.146
gishgilgamesh0.144
RelRelish0.142
Tbp-1Tat-binding protein-10.142
tostosca0.142
CycGCyclin G0.142
MadMothers against dpp0.141
CG5555CG5555 gene product from transcript CG5555-RA0.141
domdomino0.141
ph-ppolyhomeotic proximal0.141
Su(H)Suppressor of Hairless0.141
RagACG11968 gene product from transcript CG11968-RA0.140
idaimaginal discs arrested0.139
Kap-alpha3karyopherin alpha30.139
CG2046CG2046 gene product from transcript CG2046-RA0.138
CG15141CG15141 gene product from transcript CG15141-RA0.137
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
UBCubiquitin C1.000
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 41.000
SKP1S-phase kinase-associated protein 11.000
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)1.000
XIAPX-linked inhibitor of apoptosis1.000
CUL1cullin 11.000
VCPvalosin containing protein1.000
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)1.000
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)1.000
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)1.000
RNF11ring finger protein 111.000
CDC20cell division cycle 20 homolog (S. cerevisiae)1.000
UBE2V1ubiquitin-conjugating enzyme E2 variant 11.000
CDC27cell division cycle 27 homolog (S. cerevisiae)0.999
UBQLN1ubiquilin 10.999
SMAD2SMAD family member 20.999
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.999
CUL3cullin 30.999
RB1retinoblastoma 10.998
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.998
MDM2Mdm2 p53 binding protein homolog (mouse)0.997
RBX1ring-box 1, E3 ubiquitin protein ligase0.996
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.996
TP53tumor protein p530.995
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.994
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.993
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.989
SKP2S-phase kinase-associated protein 2 (p45)0.986
SQSTM1sequestosome 10.984
OTUB1OTU domain, ubiquitin aldehyde binding 10.983
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.981
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.981
ATXN3ataxin 30.980
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.980
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.979
PTK2PTK2 protein tyrosine kinase 20.979
CCNA2cyclin A20.978
CCNB1cyclin B10.978
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.978
RNF5ring finger protein 50.978
TRAF6TNF receptor-associated factor 60.977
ZNRF1zinc and ring finger 10.974
BRCA1breast cancer 1, early onset0.969
BTRCbeta-transducin repeat containing0.969
ANAPC4anaphase promoting complex subunit 40.967
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.966
FBXW11F-box and WD repeat domain containing 110.966
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.964
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.962
CDK2cyclin-dependent kinase 20.962
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.962
SMURF2SMAD specific E3 ubiquitin protein ligase 20.961
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.961
SIAH1seven in absentia homolog 1 (Drosophila)0.960
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.959
PLK1polo-like kinase 10.958
CDC16cell division cycle 16 homolog (S. cerevisiae)0.958
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.954
PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)0.952
POMPproteasome maturation protein0.951
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.948
UHRF2ubiquitin-like with PHD and ring finger domains 20.945
CKS1BCDC28 protein kinase regulatory subunit 1B0.940
UBE3Aubiquitin protein ligase E3A0.939
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.936
FBXO5F-box protein 50.935
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.934
MAP3K7mitogen-activated protein kinase kinase kinase 70.934
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.933
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.932
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.927
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.918
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.917
UBA1ubiquitin-like modifier activating enzyme 10.916
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.905
RNF111ring finger protein 1110.904
SMAD3SMAD family member 30.902
SMURF1SMAD specific E3 ubiquitin protein ligase 10.897
NEDD8neural precursor cell expressed, developmentally down-regulated 80.895
MARCH7membrane-associated ring finger (C3HC4) 70.893
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.892
ARIH2ariadne homolog 2 (Drosophila)0.888
TRIM39tripartite motif containing 390.883
SYVN1synovial apoptosis inhibitor 1, synoviolin0.882
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.882
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.878
ANAPC11anaphase promoting complex subunit 110.876
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.873
PSEN1presenilin 10.869
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.863
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.860
HSPA8heat shock 70kDa protein 80.857
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.855
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.849
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.843
HSPA4heat shock 70kDa protein 40.835
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.825
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.824
UFD1Lubiquitin fusion degradation 1 like (yeast)0.823
UBXN7UBX domain protein 70.820
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Ctnnb1catenin (cadherin associated protein), beta 10.998
Psen1presenilin 10.994
Axin1axin 10.994
Mdm2transformed mouse 3T3 cell double minute 20.989
Psmb7proteasome (prosome, macropain) subunit, beta type 70.982
Per2period homolog 2 (Drosophila)0.974
Gsk3bglycogen synthase kinase 3 beta0.972
Psma7proteasome (prosome, macropain) subunit, alpha type 70.972
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.964
Arntlaryl hydrocarbon receptor nuclear translocator-like0.958
Psma3proteasome (prosome, macropain) subunit, alpha type 30.952
Psma1proteasome (prosome, macropain) subunit, alpha type 10.947
Cdk1cyclin-dependent kinase 10.943
Ccnb1cyclin B10.931
Rnf111ring finger 1110.928
Ncstnnicastrin0.926
Ptenphosphatase and tensin homolog0.909
Apcadenomatosis polyposis coli0.906
Cry2cryptochrome 2 (photolyase-like)0.905
Ccnb2cyclin B20.897
Appamyloid beta (A4) precursor protein0.897
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.887
Psma5proteasome (prosome, macropain) subunit, alpha type 50.886
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.877
Psma2proteasome (prosome, macropain) subunit, alpha type 20.872
Clockcircadian locomotor output cycles kaput0.869
Psma6proteasome (prosome, macropain) subunit, alpha type 60.868
Psmb6proteasome (prosome, macropain) subunit, beta type 60.844
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.839
Per1period homolog 1 (Drosophila)0.838
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.818
Csnk1ecasein kinase 1, epsilon0.804
Rnf2ring finger protein 20.782
Smad7MAD homolog 7 (Drosophila)0.778
Pompproteasome maturation protein0.772
Ccna2cyclin A20.765
Mdm4transformed mouse 3T3 cell double minute 40.764
Traf6TNF receptor-associated factor 60.742
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.716
Rnf19aring finger protein 19A0.711
Aampangio-associated migratory protein0.705
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.701
Ncoa3nuclear receptor coactivator 30.701
Birc5baculoviral IAP repeat-containing 50.691
Rrm2ribonucleotide reductase M20.682
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.675
SkilSKI-like0.665
Vcpvalosin containing protein0.649
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.647
Vdac3voltage-dependent anion channel 30.647
Nedd4neural precursor cell expressed, developmentally down-regulated 40.645
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.638
Git1G protein-coupled receptor kinase-interactor 10.636
Pias2protein inhibitor of activated STAT 20.631
Sap18Sin3-associated polypeptide 180.629
Arrb2arrestin, beta 20.618
E2f8E2F transcription factor 80.609
Smurf2SMAD specific E3 ubiquitin protein ligase 20.604
Ect2ect2 oncogene0.600
Cry1cryptochrome 1 (photolyase-like)0.599
Arid1bAT rich interactive domain 1B (SWI-like)0.597
C330027C09RikRIKEN cDNA C330027C09 gene0.596
Kif20akinesin family member 20A0.593
Csnk1dcasein kinase 1, delta0.588
Arrb1arrestin, beta 10.581
Aurkaaurora kinase A0.579
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.575
Mbd3methyl-CpG binding domain protein 30.573
Anapc2anaphase promoting complex subunit 20.562
Cyldcylindromatosis (turban tumor syndrome)0.556
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.536
Ranbp9RAN binding protein 90.536
Psmb4proteasome (prosome, macropain) subunit, beta type 40.534
Prc1protein regulator of cytokinesis 10.533
Csnk1g2casein kinase 1, gamma 20.533
Atf4activating transcription factor 40.526
Tsc2tuberous sclerosis 20.526
Yap1yes-associated protein 10.523
Add1adducin 1 (alpha)0.522
Fgfr1fibroblast growth factor receptor 10.510
Pcnaproliferating cell nuclear antigen0.484
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.482
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.478
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.474
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.464
Rbl2retinoblastoma-like 20.448
Dctn1dynactin 10.445
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.442
H2afxH2A histone family, member X0.431
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.425
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.413
Hmmrhyaluronan mediated motility receptor (RHAMM)0.411
Mki67antigen identified by monoclonal antibody Ki 670.411
Manfmesencephalic astrocyte-derived neurotrophic factor0.409
Mpp5membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)0.405
Ptch1patched homolog 10.404
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.398
Crb2crumbs homolog 2 (Drosophila)0.390
Gnb2guanine nucleotide binding protein (G protein), beta 20.390
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psma5proteasome (prosome, macropain) subunit, alpha type 50.993
Psmb3proteasome (prosome, macropain) subunit, beta type 30.886
Psma4proteasome (prosome, macropain) subunit, alpha type 40.722
Psmb6proteasome (prosome, macropain) subunit, beta type 60.658
Psmb4proteasome (prosome, macropain) subunit, beta type 40.609
Psma3proteasome (prosome, macropain) subunit, alpha type 30.495
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.487
Psma7proteasome (prosome, macropain) subunit, alpha type 70.483
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.346
Psme2proteasome (prosome, macropain) activator subunit 20.305
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.293
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.276
Psmb10proteasome (prosome, macropain) subunit, beta type 100.265
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.232
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.206
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.205
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.199
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.187
Cand1cullin-associated and neddylation-dissociated 10.174
Psmb2proteasome (prosome, macropain) subunit, beta type 20.171
Psmb7proteasome (prosome, macropain) subunit, beta type 70.152
Txnl1thioredoxin-like 10.132
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.130
Psma2proteasome (prosome, macropain) subunit, alpha type 20.130
Zfand5zinc finger, AN1-type domain 50.113
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.101
Psma6proteasome (prosome, macropain) subunit, alpha type 60.099
Senp2Sumo1/sentrin/SMT3 specific peptidase 20.099
Nsfl1cNSFL1 (p97) cofactor (p47)0.088
CnbpCCHC-type zinc finger, nucleic acid binding protein0.079
Psmb5proteasome (prosome, macropain) subunit, beta type 50.079
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.074
LOC362855P550.065
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.061
Psmb1proteasome (prosome, macropain) subunit, beta type 10.061
Dctn4dynactin 40.060
Pompproteasome maturation protein0.058
Vcpvalosin-containing protein0.057
Pfn1profilin 10.056
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.054
Alkbh5alkB, alkylation repair homolog 5 (E. coli)0.053
Eif2s2eukaryotic translation initiation factor 2, subunit 2 beta0.053
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.053
Mapre1microtubule-associated protein, RP/EB family, member 10.052
Mgat2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.051
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.048
Herpud1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 10.045
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.043
Serp1stress-associated endoplasmic reticulum protein 10.043
Rab21RAB21, member RAS oncogene family0.042
Psma1proteasome (prosome, macropain) subunit, alpha type 10.041
Usp47ubiquitin specific peptidase 470.041
Brcc3BRCA1/BRCA2-containing complex, subunit 30.040
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.040
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.040
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.040
Tolliptoll interacting protein0.039
Ccnb1cyclin B10.038
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.038
Phaxphosphorylated adaptor for RNA export0.037
Pdia3protein disulfide isomerase family A, member 30.037
Ubcubiquitin C0.036
RGD1309102similar to TRS85 homolog0.035
Socs6suppressor of cytokine signaling 60.035
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.033
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.033
Zfp364zinc finger protein 3640.033
Ufd1lubiquitin fusion degradation 1 like (yeast)0.033
March5membrane-associated ring finger (C3HC4) 50.031
Lsm14aLSM14A, SCD6 homolog A (S. cerevisiae)0.031
Rnf2ring finger protein 20.031
Ndfip2Nedd4 family interacting protein 20.029
Foxm1forkhead box M10.028
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.028
Mdm2Mdm2 p53 binding protein homolog (mouse)0.027
Irf1interferon regulatory factor 10.027
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.027
Dnpepaspartyl aminopeptidase0.026
Usp15ubiquitin specific peptidase 150.026
Rbbp7retinoblastoma binding protein 70.026
Pdia4protein disulfide isomerase family A, member 40.026
Txnrd1thioredoxin reductase 10.025
Ptges3prostaglandin E synthase 3 (cytosolic)0.024
Ifi35interferon-induced protein 350.023
RybpRING1 and YY1 binding protein0.023
VapaVAMP (vesicle-associated membrane protein)-associated protein A0.023
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.023
Canxcalnexin0.022
Pttg1pituitary tumor-transforming 10.022
Usp14ubiquitin specific peptidase 140.022
Tbcbtubulin folding cofactor B0.022
Rab11aRAB11a, member RAS oncogene family0.021
Rps5ribosomal protein S50.021
Slc35b1solute carrier family 35, member B10.021
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.021
Ergic3ERGIC and golgi 30.021
Slmapsarcolemma associated protein0.020
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.020
Stx12syntaxin 120.020
Dnajc21DnaJ (Hsp40) homolog, subfamily C, member 210.019