The network for 'cleavage involved in rrna processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cleavage involved in rrna processing

Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.

NameDescriptionProbabilityFunc Analog Organism
RRP46Rrp46p0.999
RRP45Rrp45p0.992
CSL4Csl4p0.983
RRP40Rrp40p0.963
ENP1Enp1p0.957
NOP1Nop1p0.955
MTR3Mtr3p0.955
LRP1Lrp1p0.943
ECM16Ecm16p0.943
UTP10Utp10p0.929
SOF1Sof1p0.917
DIS3Dis3p0.896
RRP4Rrp4p0.887
MRD1Mrd1p0.884
PXR1Pxr1p0.878
BFR2Bfr2p0.850
KRR1Krr1p0.842
SKI6Ski6p0.822
FAF1Faf1p0.809
UTP13Utp13p0.797
MPP6Mpp6p0.735
SLX9Slx9p0.724
UTP18Utp18p0.704
ESF2Esf2p0.696
RIO1Rio1p0.685
RRP42Rrp42p0.683
UTP20Utp20p0.678
ENP2Enp2p0.671
NOP14Nop14p0.666
UBP10Ubp10p0.655
NOP6Nop6p0.642
NOP8Nop8p0.637
TRM112Trm112p0.628
IMP3Imp3p0.600
UTP8Utp8p0.593
RRP14Rrp14p0.584
UTP11Utp11p0.575
ESF1Esf1p0.575
UTP25Utp25p0.545
NOC4Noc4p0.535
NOP12Nop12p0.525
FUN12Fun12p0.517
RPF1Rpf1p0.494
NAN1Nan1p0.492
RRP43Rrp43p0.474
DIP2Dip2p0.453
PRP43Prp43p0.428
CBF5Cbf5p0.407
IMP4Imp4p0.384
UTP23Utp23p0.381
RPS17ARps17ap0.358
NAF1Naf1p0.352
GAR1Gar1p0.344
MPP10Mpp10p0.341
KRE33Kre33p0.330
RRP9Rrp9p0.327
RRP7Rrp7p0.321
SKI7Ski7p0.317
PWP2Pwp2p0.316
RRP5Rrp5p0.308
RPS21ARps21ap0.292
HMT1Hmt1p0.281
NOP56Nop56p0.279
PNO1Pno1p0.275
EBP2Ebp2p0.264
RRP12Rrp12p0.259
NOP10Nop10p0.254
UTP22Utp22p0.253
SAS10Sas10p0.245
BMS1Bms1p0.244
LCP5Lcp5p0.243
BUD21Bud21p0.221
UTP21Utp21p0.211
IMD2Imd2p0.211
UTP7Utp7p0.202
CWC24Cwc24p0.201
NOP2Nop2p0.195
SQT1Sqt1p0.191
RIO2Rio2p0.188
PAB1Pab1p0.172
NOP58Nop58p0.171
RRN3Rrn3p0.170
RRP6Rrp6p0.168
RRP36Rrp36p0.166
SEN15Sen15p0.166
DBP7Dbp7p0.163
FCF1Fcf1p0.148
UTP4Utp4p0.145
RPS11BRps11bp0.144
DHR2Dhr2p0.144
TMA23Tma23p0.137
CBR1Cbr1p0.127
DRS1Drs1p0.125
TSR1Tsr1p0.124
RPL22ARpl22ap0.123
AIR1Air1p0.123
DBP3Dbp3p0.116
NOB1Nob1p0.109
RBG1Rbg1p0.108
SNU13Snu13p0.108
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_C24H12.4Protein C24H12.40.736
ZK430.7Protein ZK430.70.686
W07E6.2Protein W07E6.20.607
CELE_T04A8.6Protein T04A8.60.572
pro-1Protein PRO-10.515
acin-1Protein ACIN-10.486
CELE_T06E6.1Protein T06E6.10.470
CELE_F53F4.11Protein F53F4.110.460
wdr-46Protein WDR-460.430
dao-5Protein DAO-50.400
elpc-3Protein ELPC-30.395
tag-184Protein TAG-1840.373
F27C1.6Protein F27C1.60.363
CELE_T26G10.1Protein T26G10.10.355
C44E4.4Protein C44E4.40.328
K07H8.10Protein K07H8.100.328
C37H5.5Protein C37H5.50.310
Y53C12B.1Protein Y53C12B.10.269
prp-3Protein PRP-30.254
suf-1Protein SUF-10.236
K12H4.3Protein K12H4.30.233
rbd-1Protein RBD-10.232
nst-1Protein NST-10.224
rrbs-1Protein RRBS-10.219
F54C9.9Protein F54C9.90.218
M28.5Protein M28.50.202
tag-151Protein TAG-1510.194
W09C3.4Protein W09C3.40.192
ZK1127.4Protein ZK1127.40.181
dbr-1Protein DBR-10.174
F09F7.3Protein F09F7.30.172
CELE_Y48B6A.1Protein Y48B6A.10.155
Y66H1A.4Protein Y66H1A.40.153
CELE_ZK795.3Protein ZK795.30.150
ZK418.9Protein ZK418.90.137
rha-2Protein RHA-20.133
F10E9.4Protein F10E9.40.127
nol-5Protein NOL-50.126
toe-1Protein TOE-10.118
C47E12.7Protein C47E12.70.113
trm-1Protein TRM-10.106
ZK792.5Protein ZK792.50.105
exos-9Protein EXOS-90.102
F55F8.2Protein F55F8.20.099
dnj-17Protein DNJ-170.099
Y45F10D.7Protein Y45F10D.70.097
dnj-19Protein DNJ-190.093
tag-124Protein TAG-1240.093
CELE_C16C10.2Protein C16C10.20.091
ngp-1Protein NGP-10.090
W04C9.4Protein W04C9.40.085
tut-1Protein TUT-10.081
C05C8.2Protein C05C8.20.079
C53H9.2Protein C53H9.20.077
ZK512.2Protein ZK512.20.077
K07C5.4Protein K07C5.40.076
K04C2.2Protein K04C2.20.076
CELE_C23G10.8Protein C23G10.80.075
ZK546.14Protein ZK546.140.075
Y37E11B.5Protein Y37E11B.50.071
T20B12.3Protein T20B12.30.069
C27F2.4Protein C27F2.40.069
Y49F6B.2Protein Y49F6B.20.067
Y110A7A.19Protein Y110A7A.190.067
F49D11.10Protein F49D11.100.065
K01G5.5Protein K01G5.50.064
T11G6.8Protein T11G6.80.063
fust-1Protein FUST-10.061
E02H1.1Protein E02H1.10.061
Y54E10A.10Protein Y54E10A.100.060
fcp-1Protein FCP-10.060
F25B5.5Protein F25B5.50.059
T12E12.3Protein T12E12.30.056
F53E10.6Protein F53E10.60.053
R02F2.7Protein R02F2.70.051
nol-1Protein NOL-10.050
cir-1Protein CIR-10.049
mrps-18CProtein MRPS-18C0.049
T10B5.3Protein T10B5.30.047
CELE_W03F9.10Protein W03F9.100.046
pro-2Protein PRO-20.044
F45F2.11Protein F45F2.110.044
nath-10Protein NATH-100.042
CELE_W02A11.1Protein W02A11.10.042
C18A3.3Protein C18A3.30.041
CELE_F07E5.5Protein F07E5.50.041
Y46E12BL.2Protein Y46E12BL.20.040
ZK686.2Protein ZK686.20.040
CELE_Y41D4B.11Protein Y41D4B.110.039
riok-1Protein RIOK-10.038
spt-5Protein SPT-50.038
rnp-3Protein RNP-30.037
cdc-48.3Protein CDC-48.30.037
puf-12Protein PUF-120.037
F11A10.7Protein F11A10.70.037
eif-3.EProtein EIF-3.E0.037
F37A4.2Protein F37A4.20.037
prp-21Protein PRP-210.036
R186.7Protein R186.70.034
thoc-2Protein THOC-20.033
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Wdr43WD repeat domain 430.649
Mybbp1aMYB binding protein (P160) 1a0.636
Ppanpeter pan homolog (Drosophila)0.471
Ddx21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.463
Gnl3guanine nucleotide binding protein-like 3 (nucleolar)0.420
Rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.401
Nop2NOP2 nucleolar protein homolog (yeast)0.384
Utp20UTP20, small subunit (SSU) processome component, homolog (yeast)0.330
Smyd5SET and MYND domain containing 50.279
Grwd1glutamate-rich WD repeat containing 10.269
Pprc1peroxisome proliferative activated receptor, gamma, coactivator-related 10.256
Ftsj3FtsJ homolog 3 (E. coli)0.220
Rrp15ribosomal RNA processing 15 homolog (S. cerevisiae)0.201
Nop56NOP56 ribonucleoprotein homolog (yeast)0.194
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.164
Mettl1methyltransferase like 10.156
Ccdc86coiled-coil domain containing 860.147
D19Bwg1357eDNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed0.126
Srmspermidine synthase0.122
Rrp1bribosomal RNA processing 1 homolog B (S. cerevisiae)0.112
Heatr1HEAT repeat containing 10.109
Tsr1TSR1, 20S rRNA accumulation, homolog (yeast)0.102
Nsun2NOL1/NOP2/Sun domain family member 20.099
Wdr74WD repeat domain 740.093
Rrp9RRP9, small subunit (SSU) processome component, homolog (yeast)0.093
Nolc1nucleolar and coiled-body phosphoprotein 10.090
Atad3aATPase family, AAA domain containing 3A0.070
Fam203afamily with sequence similarity 203, member A0.067
Tarsthreonyl-tRNA synthetase0.058
Noc4lnucleolar complex associated 4 homolog (S. cerevisiae)0.057
Polr1bpolymerase (RNA) I polypeptide B0.056
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.055
Pus1pseudouridine synthase 10.053
Wdr75WD repeat domain 750.052
Nop14NOP14 nucleolar protein homolog (yeast)0.050
Dis3DIS3 mitotic control homolog (S. cerevisiae)0.046
Spata5spermatogenesis associated 50.046
Cpsf2cleavage and polyadenylation specific factor 20.044
Mki67ipMki67 (FHA domain) interacting nucleolar phosphoprotein0.043
Prpf3PRP3 pre-mRNA processing factor 3 homolog (yeast)0.042
Sf3b3splicing factor 3b, subunit 30.042
Pwp2PWP2 periodic tryptophan protein homolog (yeast)0.042
Gtpbp4GTP binding protein 40.041
Ddx20DEAD (Asp-Glu-Ala-Asp) box polypeptide 200.040
Ltv1LTV1 homolog (S. cerevisiae)0.040
Ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.039
Wdr46WD repeat domain 460.038
Ddx54DEAD (Asp-Glu-Ala-Asp) box polypeptide 540.038
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.037
Nubp1nucleotide binding protein 10.037
Elac2elaC homolog 2 (E. coli)0.036
Brix1BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)0.036
Rrs1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.034
Lrrc40leucine rich repeat containing 400.033
CebpzCCAAT/enhancer binding protein zeta0.033
Aatfapoptosis antagonizing transcription factor0.033
Sdad1SDA1 domain containing 10.032
Nufip1nuclear fragile X mental retardation protein interacting protein 10.030
Mycmyelocytomatosis oncogene0.030
Fblfibrillarin0.029
Noc3lnucleolar complex associated 3 homolog (S. cerevisiae)0.029
Eif1aeukaryotic translation initiation factor 1A0.029
Gpatch4G patch domain containing 40.029
Gar1GAR1 ribonucleoprotein homolog (yeast)0.029
Tex10testis expressed gene 100.027
Haus6HAUS augmin-like complex, subunit 60.027
Pa2g4proliferation-associated 2G40.026
Pus7lpseudouridylate synthase 7 homolog (S. cerevisiae)-like0.026
U2af1U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 10.026
Nop16NOP16 nucleolar protein homolog (yeast)0.025
Polr1apolymerase (RNA) I polypeptide A0.025
Zfp259zinc finger protein 2590.024
Nip7nuclear import 7 homolog (S. cerevisiae)0.023
Eedembryonic ectoderm development0.023
2610027L16RikRIKEN cDNA 2610027L16 gene0.023
Msh6mutS homolog 6 (E. coli)0.022
Xpo5exportin 50.022
Polr3apolymerase (RNA) III (DNA directed) polypeptide A0.021
Ino80eINO80 complex subunit E0.021
Ccar1cell division cycle and apoptosis regulator 10.021
Utp15UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.021
Cirh1acirrhosis, autosomal recessive 1A (human)0.020
Trp53transformation related protein 530.020
Imp4IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.020
Dph2DPH2 homolog (S. cerevisiae)0.019
Rbm34RNA binding motif protein 340.019
Varsvalyl-tRNA synthetase0.019
TwistnbTWIST neighbor0.019
Ints5integrator complex subunit 50.019
Mak16MAK16 homolog (S. cerevisiae)0.018
Larp7La ribonucleoprotein domain family, member 70.018
Tbrg4transforming growth factor beta regulated gene 40.018
Ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.018
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.017
Wdr55WD repeat domain 550.017
Nol8nucleolar protein 80.017
Pdcd11programmed cell death 110.017
Ddx51DEAD (Asp-Glu-Ala-Asp) box polypeptide 510.017
Exosc10exosome component 100.017
Ifrd2interferon-related developmental regulator 20.017
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism