The network for 'camp mediated signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

camp mediated signaling

Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox9bSRY-box containing gene 9b0.014
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CaMKIICalcium/calmodulin-dependent protein kinase II0.016
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
IL8interleukin 80.976
ARRB1arrestin, beta 10.966
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.964
CCL5chemokine (C-C motif) ligand 50.953
CXCL2chemokine (C-X-C motif) ligand 20.927
CXCL3chemokine (C-X-C motif) ligand 30.904
MEOX2mesenchyme homeobox 20.898
IL1Binterleukin 1, beta0.866
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.853
CCR5chemokine (C-C motif) receptor 50.815
MPDZmultiple PDZ domain protein0.743
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.699
CXCL10chemokine (C-X-C motif) ligand 100.699
CCL20chemokine (C-C motif) ligand 200.692
CXCL11chemokine (C-X-C motif) ligand 110.619
DPP4dipeptidyl-peptidase 40.618
IFNGinterferon, gamma0.614
PAX3paired box 30.614
TBXA2Rthromboxane A2 receptor0.538
CRHcorticotropin releasing hormone0.534
POU3F2POU class 3 homeobox 20.465
CCR2chemokine (C-C motif) receptor 20.450
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.427
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.416
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.411
IL6interleukin 6 (interferon, beta 2)0.393
CXCL5chemokine (C-X-C motif) ligand 50.368
CXCR5chemokine (C-X-C motif) receptor 50.362
PTGIRprostaglandin I2 (prostacyclin) receptor (IP)0.354
PLEKHA1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 10.344
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.327
CXCL9chemokine (C-X-C motif) ligand 90.317
CCL4chemokine (C-C motif) ligand 40.308
CXCR3chemokine (C-X-C motif) receptor 30.290
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.285
CCL8chemokine (C-C motif) ligand 80.245
IL10interleukin 100.234
SKP1S-phase kinase-associated protein 10.213
SSTR3somatostatin receptor 30.212
CCL22chemokine (C-C motif) ligand 220.205
CCL2chemokine (C-C motif) ligand 20.157
IL2RBinterleukin 2 receptor, beta0.147
TBC1D10ATBC1 domain family, member 10A0.146
CCL7chemokine (C-C motif) ligand 70.125
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.122
CXCL13chemokine (C-X-C motif) ligand 130.114
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.111
CCR4chemokine (C-C motif) receptor 40.108
CCL11chemokine (C-C motif) ligand 110.098
CD40LGCD40 ligand0.096
CCR7chemokine (C-C motif) receptor 70.094
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.091
NEDD4neural precursor cell expressed, developmentally down-regulated 40.091
CCL19chemokine (C-C motif) ligand 190.089
INF2inverted formin, FH2 and WH2 domain containing0.086
PTGER3prostaglandin E receptor 3 (subtype EP3)0.083
RAMP3receptor (G protein-coupled) activity modifying protein 30.081
EIF4Eeukaryotic translation initiation factor 4E0.080
IRF4interferon regulatory factor 40.078
SSTR2somatostatin receptor 20.078
UBA1ubiquitin-like modifier activating enzyme 10.070
SMAD7SMAD family member 70.069
FBXW5F-box and WD repeat domain containing 50.067
FCER2Fc fragment of IgE, low affinity II, receptor for (CD23)0.064
CLEC7AC-type lectin domain family 7, member A0.063
CXCR2chemokine (C-X-C motif) receptor 20.061
PF4platelet factor 40.060
MAPK10mitogen-activated protein kinase 100.053
GPR6G protein-coupled receptor 60.053
CXCR6chemokine (C-X-C motif) receptor 60.052
OPRM1opioid receptor, mu 10.050
ARRDC3arrestin domain containing 30.048
BZW1basic leucine zipper and W2 domains 10.048
SLC30A3solute carrier family 30 (zinc transporter), member 30.047
CCL3chemokine (C-C motif) ligand 30.044
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.043
SELEselectin E0.042
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.042
UBDubiquitin D0.041
LTAlymphotoxin alpha (TNF superfamily, member 1)0.041
CALCAcalcitonin-related polypeptide alpha0.040
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.039
GIMAP4GTPase, IMAP family member 40.039
MMP12matrix metallopeptidase 12 (macrophage elastase)0.039
RAP1ARAP1A, member of RAS oncogene family0.039
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.039
IER3immediate early response 30.039
SLAMF7SLAM family member 70.039
RGS1regulator of G-protein signaling 10.038
CACYBPcalcyclin binding protein0.038
ADRA1Dadrenergic, alpha-1D-, receptor0.038
CHRNA4cholinergic receptor, nicotinic, alpha 40.038
HTR1B5-hydroxytryptamine (serotonin) receptor 1B0.038
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.037
PPBPpro-platelet basic protein (chemokine (C-X-C motif) ligand 7)0.037
FOXD3forkhead box D30.037
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.036
ARRB2arrestin, beta 20.036
BTRCbeta-transducin repeat containing0.035
ADRB3adrenergic, beta-3-, receptor0.035
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc34a1solute carrier family 34 (sodium phosphate), member 10.924
Leprleptin receptor0.920
Adrb1adrenergic receptor, beta 10.849
Drd2dopamine receptor D20.815
Esr1estrogen receptor 1 (alpha)0.525
Cckbrcholecystokinin B receptor0.522
Rims2regulating synaptic membrane exocytosis 20.475
Pnpla2patatin-like phospholipase domain containing 20.452
Shc3src homology 2 domain-containing transforming protein C30.451
Kiss1KiSS-1 metastasis-suppressor0.433
Retret proto-oncogene0.271
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.240
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.176
Hcn1hyperpolarization-activated, cyclic nucleotide-gated K+ 10.157
Npy2rneuropeptide Y receptor Y20.130
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.118
Slc17a1solute carrier family 17 (sodium phosphate), member 10.113
Vdrvitamin D receptor0.112
Edil3EGF-like repeats and discoidin I-like domains 30.098
Rgs9regulator of G-protein signaling 90.093
Pgrprogesterone receptor0.092
Rims1regulating synaptic membrane exocytosis 10.091
Kcnk3potassium channel, subfamily K, member 30.089
Crhr1corticotropin releasing hormone receptor 10.087
Gad2glutamic acid decarboxylase 20.085
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.085
Ppargperoxisome proliferator activated receptor gamma0.081
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.078
Gnrhrgonadotropin releasing hormone receptor0.076
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.074
Adrb3adrenergic receptor, beta 30.072
Lrp6low density lipoprotein receptor-related protein 60.067
Fgf10fibroblast growth factor 100.065
Npy5rneuropeptide Y receptor Y50.064
Cftrcystic fibrosis transmembrane conductance regulator homolog0.063
Thrbthyroid hormone receptor beta0.063
Gpr33G protein-coupled receptor 330.062
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.061
Oprk1opioid receptor, kappa 10.060
Nppbnatriuretic peptide type B0.060
Arnt2aryl hydrocarbon receptor nuclear translocator 20.060
Fgf8fibroblast growth factor 80.059
Arandrogen receptor0.057
Cybbcytochrome b-245, beta polypeptide0.057
Foxf2forkhead box F20.057
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.055
Cdh8cadherin 80.055
Epha6Eph receptor A60.055
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.053
Sstr2somatostatin receptor 20.053
Sstr3somatostatin receptor 30.053
Cdh4cadherin 40.051
Kiss1rKISS1 receptor0.051
Ghrgrowth hormone receptor0.049
Syn2synapsin II0.049
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.048
Zfpm2zinc finger protein, multitype 20.048
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.047
Csmd1CUB and Sushi multiple domains 10.047
Plcb1phospholipase C, beta 10.046
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.045
Sstr4somatostatin receptor 40.044
Fgfr3fibroblast growth factor receptor 30.044
Syt1synaptotagmin I0.044
Adora2aadenosine A2a receptor0.043
Trpc5transient receptor potential cation channel, subfamily C, member 50.042
Trpc4transient receptor potential cation channel, subfamily C, member 40.041
Gpr83G protein-coupled receptor 830.041
Pthlhparathyroid hormone-like peptide0.041
RorbRAR-related orphan receptor beta0.040
Kcnc1potassium voltage gated channel, Shaw-related subfamily, member 10.040
Syt7synaptotagmin VII0.040
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.039
Cdh6cadherin 60.039
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.039
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.039
Tac2tachykinin 20.039
Lmx1bLIM homeobox transcription factor 1 beta0.038
Avpr2arginine vasopressin receptor 20.038
Kifc2kinesin family member C20.037
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.037
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.037
Npy6rneuropeptide Y receptor Y60.036
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.036
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.036
Slc16a8solute carrier family 16 (monocarboxylic acid transporters), member 80.036
Trfr2transferrin receptor 20.035
Cux2cut-like homeobox 20.035
Gcet2germinal center expressed transcript 20.035
Cntn3contactin 30.035
Nrg3neuregulin 30.035
Gpr12G-protein coupled receptor 120.035
Hand2heart and neural crest derivatives expressed transcript 20.035
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.035
Pdx1pancreatic and duodenal homeobox 10.035
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.035
Wnt7awingless-related MMTV integration site 7A0.034
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism