The network for 'death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

death

A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.

NameDescriptionProbabilityFunc Analog Organism
HSP82Hsp82p0.205
TEF4Tef4p0.180
SLT2Slt2p0.167
BMH1Bmh1p0.107
HYP2Hyp2p0.105
MSH2Msh2p0.099
RFC1Rfc1p0.093
ARB1Arb1p0.087
RAD3Rad3p0.083
RPS1ARps1ap0.079
DHH1Dhh1p0.078
SSA1Ssa1p0.073
RPS3Rps3p0.073
YAP1Yap1p0.070
TIF35Tif35p0.067
RPL10Rpl10p0.064
RPG1Rpg1p0.062
TSA1Tsa1p0.061
CCT6Cct6p0.060
TIF5Tif5p0.059
PRE10Pre10p0.059
PIL1Pil1p0.057
RPL19BRpl19bp0.057
STI1Sti1p0.056
SSA3Ssa3p0.055
CCR4Ccr4p0.054
AQY2Aqy2p0.054
CBF2Cbf2p0.052
YGL242Chypothetical protein0.052
PKH2Pkh2p0.052
NDE1Nde1p0.051
DSK2Dsk2p0.051
RPL16BRpl16bp0.050
KSS1Kss1p0.047
CDC37Cdc37p0.047
RPT6Rpt6p0.046
VMA13Vma13p0.046
PIM1Pim1p0.046
RPS6BRps6bp0.045
ERB1Erb1p0.043
RAD54Rad54p0.043
SOD2Sod2p0.042
SAP1Sap1p0.042
TAF11Taf11p0.040
UBP9Ubp9p0.040
SUB2Sub2p0.040
SSA2Ssa2p0.040
MSH3Msh3p0.039
YHR033Whypothetical protein0.039
TRA1Tra1p0.039
PRK1Prk1p0.039
YPK2Ypk2p0.038
KAR2Kar2p0.038
NBL1Nbl1p0.037
ECM29Ecm29p0.037
PBS2Pbs2p0.037
BFR1Bfr1p0.037
NSA1Nsa1p0.037
CDC55Cdc55p0.037
GUS1Gus1p0.037
CDC48Cdc48p0.036
MKT1Mkt1p0.036
SCH9Sch9p0.034
NUP157Nup157p0.034
VPS27Vps27p0.034
NMA111Nma111p0.034
RPL13ARpl13ap0.033
SSE1Sse1p0.033
SSZ1Ssz1p0.033
GUT2Gut2p0.033
GPM1Gpm1p0.033
SUI1Sui1p0.033
RPL1ARpl1ap0.032
ATG21Atg21p0.032
DNM1Dnm1p0.032
PPH3Pph3p0.032
RPS7ARps7ap0.032
TIM54Tim54p0.031
CCT3Cct3p0.031
YDJ1Ydj1p0.031
NOG2Nog2p0.031
ZDS2Zds2p0.031
STE5Ste5p0.030
SLI15Sli15p0.030
EAF3Eaf3p0.030
SCJ1Scj1p0.030
AKL1Akl1p0.029
NRP1Nrp1p0.029
MYO5Myo5p0.029
AHC1Ahc1p0.028
ATG14Atg14p0.028
TDH2Tdh2p0.028
RPL28Rpl28p0.028
RPT1Rpt1p0.028
VPS30Vps30p0.028
RPL32Rpl32p0.028
SSA4Ssa4p0.027
GCN20Gcn20p0.027
TEF2Tef2p0.027
SSL1Ssl1p0.027
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
kle-2Protein KLE-20.908
hsp-1Protein HSP-10.823
glp-1Protein GLP-10.819
rpl-18Protein RPL-180.798
crt-1Protein CRT-10.761
gex-3Protein GEX-30.756
mat-3Protein MAT-30.734
egl-18Protein EGL-180.723
atp-2Protein ATP-20.721
vha-8Protein VHA-80.721
ads-1Protein ADS-10.712
rme-2Protein RME-20.668
nud-2Protein NUD-20.657
lsm-5Protein LSM-50.657
vab-3Protein VAB-30.651
CELE_F14E5.2Protein F14E5.20.642
C28H8.3Protein C28H8.30.629
tbb-2Protein TBB-20.611
R10E4.1Protein R10E4.10.605
egl-44Protein EGL-440.602
zyg-9Protein ZYG-90.592
unc-60Protein UNC-600.587
ZK484.1Protein ZK484.10.586
snr-1Protein SNR-10.585
etr-1Protein ETR-10.582
rps-0Protein RPS-00.581
vha-19Protein VHA-190.572
egl-46Protein EGL-460.567
eftu-2Protein EFTU-20.561
mut-7Protein MUT-70.561
ftt-2Protein FTT-20.558
egg-6Protein EGG-60.557
C14C10.5Protein C14C10.50.553
klp-15Protein KLP-150.544
mdt-29Protein MDT-290.542
icln-1Protein ICLN-10.542
sta-1Protein STA-10.542
rps-12Protein RPS-120.540
rpl-38Protein RPL-380.538
bec-1Protein BEC-10.537
rme-4Protein RME-40.537
dlc-1Protein DLC-10.529
bub-1Protein BUB-10.529
ceh-20Protein CEH-200.529
pdfr-1Protein PDFR-10.528
rpl-16Protein RPL-160.527
unc-108Protein UNC-1080.521
gld-2Protein GLD-20.521
rps-2Protein RPS-20.521
H21P03.2Protein H21P03.20.516
inx-13Protein INX-130.516
gei-11Protein GEI-110.514
skr-8Protein SKR-80.512
tag-319Protein TAG-3190.508
Y71F9AL.1Protein Y71F9AL.10.507
rps-4Protein RPS-40.502
nmt-1Protein NMT-10.499
cgr-1Protein CGR-10.497
sax-7Protein SAX-70.491
Y65B4BR.5Protein Y65B4BR.50.490
rars-1Protein RARS-10.486
rpl-5Protein RPL-50.485
C53B4.4Protein C53B4.40.485
F39B2.1Protein F39B2.10.483
icd-1Protein ICD-10.483
mua-6Protein MUA-60.471
unc-9Protein UNC-90.467
rpl-13Protein RPL-130.466
pry-1Protein PRY-10.463
ran-5Protein RAN-50.460
hpo-32Protein HPO-320.457
ehs-1Protein EHS-10.456
gpb-2Protein GPB-20.454
F18A1.7Protein F18A1.70.451
exoc-7Protein EXOC-70.451
acs-4Protein ACS-40.450
hid-1Protein HID-10.446
npp-7Protein NPP-70.445
unc-120Protein UNC-1200.441
fbf-2Protein FBF-20.435
rpa-1Protein RPA-10.433
lmn-1Protein LMN-10.433
nhr-2Protein NHR-20.432
air-2Protein AIR-20.432
W04D2.6Protein W04D2.60.430
mpz-2Protein MPZ-20.429
ubc-20Protein UBC-200.428
rla-0Protein RLA-00.427
tre-3Protein TRE-30.427
cra-1Protein CRA-10.425
C14B1.2Protein C14B1.20.422
mrp-7Protein MRP-70.422
srgp-1Protein SRGP-10.421
rpl-4Protein RPL-40.419
dbr-1Protein DBR-10.416
K03E6.7Protein K03E6.70.415
H28O16.1Protein H28O16.10.413
rpl-11.1Protein RPL-11.10.413
mel-26Protein MEL-260.413
agef-1Protein AGEF-10.413
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.915
tbx1T-box 10.902
fgfr1afibroblast growth factor receptor 1a0.783
osr1odd-skipped related 1 (Drosophila)0.782
shhasonic hedgehog a0.763
runx2brunt-related transcription factor 2b0.751
trpm7transient receptor potential cation channel, subfamily M, member 70.732
cmybtranscription factor cmyb0.726
fgf3fibroblast growth factor 30.705
gata3GATA-binding protein 30.649
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.624
bmp4bone morphogenetic protein 40.598
rpsaribosomal protein SA0.582
gli1GLI-Kruppel family member 10.545
efnb2aephrin B2a0.539
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.531
rpl18aribosomal protein L18a0.529
ndr2nodal-related 20.521
tp63tumor protein p630.511
gscgoosecoid0.495
evplenvoplakin0.492
rpl13ribosomal protein L130.490
bbc3BCL2 binding component 30.483
wnt4awingless-type MMTV integration site family, member 4a0.481
baxabcl2-associated X protein, a0.438
evx1even-skipped homeobox 10.436
ctsl1acathepsin L, 1 a0.434
csnk1dacasein kinase 1, delta a0.427
foxo3bforkhead box O3b0.410
rpl15ribosomal protein L150.408
ptf1apancreas specific transcription factor, 1a0.403
bocbrother of CDO0.399
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.397
thtyrosine hydroxylase0.396
dkk1bdickkopf 1b0.396
ptgs2aprostaglandin-endoperoxide synthase 2a0.392
metmet proto-oncogene (hepatocyte growth factor receptor)0.385
eif4eeukaryotic translation initiation factor 4e0.384
kitakit receptor a0.374
rargaretinoic acid receptor gamma a0.371
eif3geukaryotic translation initiation factor 3, subunit G0.370
pcnaproliferating cell nuclear antigen0.369
fauaFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a0.354
lamb1alaminin, beta 1a0.349
plcg1phospholipase C, gamma 10.345
sgk1serum/glucocorticoid regulated kinase 10.340
cct8chaperonin containing TCP1, subunit 8 (theta)0.336
fezf2FEZ family zinc finger 20.336
etv2ets variant gene 20.334
zic1zic family member 1 (odd-paired homolog, Drosophila)0.334
pea3ETS-domain transcription factor pea30.333
wnt2bbwingless-type MMTV integration site family, member 2Bb0.333
dlx4adistal-less homeobox gene 4a0.331
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.331
ranras-related nuclear protein0.328
chdchordin0.323
surf6surfeit 60.312
tp53tumor protein p530.305
dmrta2doublesex and mab-3 related transcription factor like family A20.304
cnr1cannabinoid receptor 10.299
dlx5adistal-less homeobox gene 5a0.299
rpl35ribosomal protein L350.295
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.293
notch1anotch homolog 1a0.293
ikzf1IKAROS family zinc finger 1 (Ikaros)0.293
gdnfglial cell derived neurotrophic factor0.290
flncbfilamin C, gamma b (actin binding protein 280)0.290
lmx1b.1LIM homeobox transcription factor 1, beta 10.289
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.286
eomesaeomesodermin homolog a0.280
zgc:112329zgc:1123290.278
gpr126G protein-coupled receptor 1260.278
bnc2basonuclin 20.278
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.272
notch2notch homolog 20.269
tshz1teashirt family zinc finger 10.268
fabp11afatty acid binding protein 11a0.268
rpl7aribosomal protein L7a0.267
tbx20T-box 200.265
pax5paired box gene 50.265
hspa9heat shock protein 90.263
col15a1bcollagen, type XV, alpha 1b0.262
nrg2aneuregulin 2a0.262
sf3b4splicing factor 3b, subunit 40.261
rpl19ribosomal protein L190.261
col14a1collagen, type XIV, alpha 10.260
alcambactivated leukocyte cell adhesion molecule b0.259
marcksamyristoylated alanine rich protein kinase C substrate a0.256
pkd2polycystic kidney disease 20.256
lmnalamin A0.255
gro1groucho 10.254
neo1neogenin 10.252
sfrp1asecreted frizzled-related protein 1a0.248
hey1hairy/enhancer-of-split related with YRPW motif 10.248
ca8carbonic anhydrase VIII0.247
bcl2l1bcl2-like 10.247
bmperBMP binding endothelial regulator0.246
zgc:92237zgc:922370.245
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.245
mecp2methyl CpG binding protein 20.242
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
nejnejire0.999
Akt1CG4006 gene product from transcript CG4006-RA0.988
slmbsupernumerary limbs0.976
cicubitus interruptus0.971
Atg1Autophagy-specific gene 10.962
CG11347CG11347 gene product from transcript CG11347-RE0.949
Ras85DRas oncogene at 85D0.946
Pi3K92ECG4141 gene product from transcript CG4141-RB0.938
putpunt0.931
kaykayak0.926
pntpointed0.926
lolalongitudinals lacking0.914
tkvthickveins0.912
shnschnurri0.901
hephemipterous0.894
PakPAK-kinase0.891
drprdraper0.889
E(z)Enhancer of zeste0.887
effeffete0.880
CapsCalcium activated protein for secretion0.864
crolcrooked legs0.843
miltmilton0.839
shishibire0.829
numbCG3779 gene product from transcript CG3779-RB0.827
eIF-4aEukaryotic initiation factor 4a0.824
zipzipper0.820
domdomino0.819
EcREcdysone receptor0.816
InRInsulin-like receptor0.798
shgshotgun0.789
Fmr1CG6203 gene product from transcript CG6203-RC0.788
Pka-C1cAMP-dependent protein kinase 10.787
shotshort stop0.779
debcldeath executioner Bcl-2 homologue0.775
Atg18Autophagy-specific gene 180.775
skpACG16983 gene product from transcript CG16983-RD0.769
CycGCyclin G0.761
Rac1CG2248 gene product from transcript CG2248-RA0.755
dacdachshund0.749
rapretina aberrant in pattern0.747
Eip93FCG18389 gene product from transcript CG18389-RB0.743
EgfrEpidermal growth factor receptor0.739
p53CG33336 gene product from transcript CG33336-RB0.736
Eip74EFEcdysone-induced protein 74EF0.736
PvrPDGF- and VEGF-receptor related0.734
phlpole hole0.723
scnyscrawny0.722
Rho1CG8416 gene product from transcript CG8416-RB0.717
jingCG9397 gene product from transcript CG9397-RI0.703
agoarchipelago0.695
drkdownstream of receptor kinase0.694
dmdiminutive0.693
Pi3K21BCG2699 gene product from transcript CG2699-RA0.693
CG7998CG7998 gene product from transcript CG7998-RA0.684
MadMothers against dpp0.674
DadDaughters against dpp0.671
Gyc76CGuanylyl cyclase at 76C0.670
RbfRetinoblastoma-family protein0.665
RelRelish0.665
dallydivision abnormally delayed0.664
mrnmarionette0.664
jarjaguar0.661
spasspastin0.658
tlkTousled-like kinase0.654
saxsaxophone0.649
armarmadillo0.648
nubnubbin0.648
Hsp83Heat shock protein 830.643
eIF-4EEukaryotic initiation factor 4E0.642
bifbifocal0.636
PtenCG5671 gene product from transcript CG5671-RB0.628
simsingle-minded0.624
belbelle0.624
AtpalphaNa pump alpha subunit0.623
S6kRPS6-p70-protein kinase0.623
sdscalloped0.623
Pi3K59FPhosphotidylinositol 3 kinase 59F0.622
Trxr-1Thioredoxin reductase-10.609
Ef2bElongation factor 2b0.607
Aos1CG12276 gene product from transcript CG12276-RA0.602
RpL7ARibosomal protein L7A0.596
bcdbicoid0.593
G-salpha60AG protein salpha 60A0.592
CkIIalphaCasein kinase II alpha subunit0.588
p120ctnAdherens junction protein p1200.585
CG5794CG5794 gene product from transcript CG5794-RB0.583
endoAendophilin A0.574
alpha-Catalpha Catenin0.568
ushu-shaped0.567
stcksteamer duck0.563
sopstring of pearls0.558
p38bCG7393 gene product from transcript CG7393-RA0.557
ScmSex comb on midleg0.545
MAGECG10059 gene product from transcript CG10059-RA0.540
RpL9Ribosomal protein L90.538
Atg8aAutophagy-specific gene 8a0.537
Mov34CG3416 gene product from transcript CG3416-RA0.536
CycACyclin A0.531
CkIalphaCasein kinase Ialpha0.530
MoeMoesin0.529
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism