The network for 'regulation of protein complex disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein complex disassembly

Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
flot1bflotillin 1b0.151
tpm3tropomyosin 30.101
nfascaneurofascin homolog (chicken) a0.091
kif14kinesin family member 140.089
slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.084
kifc1kinesin family member C10.080
sptbspectrin, beta, erythrocytic0.065
alas2aminolevulinate, delta-, synthetase 20.061
tnnc1btroponin C type 1b (slow)0.057
prc1bprotein regulator of cytokinesis 1b0.056
LOC100536090targeting protein for Xklp2-B-like0.056
tnnt3atroponin T3a, skeletal, fast0.054
dscamDown syndrome cell adhesion molecule0.054
nhsl1bNHS-like 1b0.050
cry1acryptochrome 1a0.047
sept2septin 20.047
atp6v0cbATPase, H+ transporting, lysosomal, V0 subunit c, b0.046
inabinternexin neuronal intermediate filament protein, alpha b0.046
tbeta-abeta thymosin-like protein 20.046
cdc20cell division cycle 20 homolog0.044
cdk1cyclin-dependent kinase 10.044
rc3rabconnectin 30.043
LOC100334363Sperm acrosome membrane-associated protein 4-like0.042
tnnt3btroponin T3b, skeletal, fast0.041
tra2atransformer-2 alpha0.041
casq2calsequestrin 20.041
wdr1WD repeat domain 10.041
s100a10bS100 calcium binding protein A10b0.039
znf711zinc finger protein 7110.038
cotl1coactosin-like 1 (Dictyostelium)0.038
ube2v2ubiquitin-conjugating enzyme E2 variant 20.038
cnn2calponin 20.037
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.036
ankrd13cankyrin repeat domain 13C0.036
me2malic enzyme 2, NAD(+)-dependent, mitochondrial0.035
capza1acapping protein (actin filament) muscle Z-line, alpha 1a0.035
gsnbgelsolin b0.035
senp6aSUMO1/sentrin specific peptidase 6a0.034
vamp2vesicle-associated membrane protein 20.034
tnnt1troponin T1, skeletal, slow0.033
sfrs3bsplicing factor, arginine/serine-rich 3b0.033
h3f3aH3 histone, family 3A0.032
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.032
sass6spindle assembly 6 homolog (C. elegans)0.032
nadl1.2neural adhesion molecule L1.20.032
hnrplheterogeneous nuclear ribonucleoprotein L0.032
hhatlbhedgehog acyltransferase-like, b0.032
vapaVAMP (vesicle-associated membrane protein)-associated protein A0.032
rhdRh blood group, D antigen0.032
arhgap11aRho GTPase activating protein 11A0.031
hmga1ahigh mobility group AT-hook 1a0.031
fxyd6lFXYD domain containing ion transport regulator 6 like0.031
pfn1profilin 10.031
myl9lmyosin, light polypeptide 9, like0.031
ddcdopa decarboxylase0.031
LOC100536712hypothetical protein LOC1005367120.030
smyhc1slow myosin heavy chain 10.030
capza1bcapping protein (actin filament) muscle Z-line, alpha 1b0.030
lrmplymphoid-restricted membrane protein0.030
cybbcytochrome b-245, beta polypeptide (chronic granulomatous disease)0.030
birc5abaculoviral IAP repeat-containing 5a0.030
tnnc2troponin C type 2 (fast)0.029
hhatlahedgehog acyltransferase-like, a0.029
arhgef1rho guanine nucleotide exchange factor (GEF) 10.029
prkar2aaprotein kinase, cAMP-dependent, regulatory, type II, alpha A0.029
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.029
slc5a12solute carrier family 5 (sodium/glucose cotransporter), member 120.029
cav3caveolin 30.028
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.028
wdr82WD repeat domain containing 820.028
zfyve26zinc finger, FYVE domain containing 260.028
nt5c2l15'-nucleotidase, cytosolic II, like 10.027
hnrnpmheterogeneous nuclear ribonucleoprotein M0.027
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.027
ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.027
arpc5bactin related protein 2/3 complex, subunit 5B0.026
piguphosphatidylinositol glycan anchor biosynthesis, class U0.026
eif5aeukaryotic translation initiation factor 5A0.026
depdc1aDEP domain containing 1a0.026
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.026
cldniclaudin i0.026
hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.026
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
exo84CG6095 gene product from transcript CG6095-RA0.982
sec8CG2095 gene product from transcript CG2095-RA0.941
CG32038CG32038 gene product from transcript CG32038-RA0.907
aspabnormal spindle0.827
Klp67AKinesin-like protein at 67A0.656
Dap160Dynamin associated protein 1600.540
fwsfour way stop0.535
wupAwings up A0.435
Klp61FKinesin-like protein at 61F0.348
Arp66BActin-related protein 66B0.322
bondjames bond0.312
Spc25CG7242 gene product from transcript CG7242-RA0.300
Pak3CG14895 gene product from transcript CG14895-RA0.260
CG10722CG10722 gene product from transcript CG10722-RA0.259
htshu li tai shao0.258
poloCG12306 gene product from transcript CG12306-RA0.244
Zasp66Z band alternatively spliced PDZ-motif protein 660.242
rheaCG6831 gene product from transcript CG6831-RA0.233
ana3anastral spindle 30.203
Cog7CG31040 gene product from transcript CG31040-RA0.186
PpcsPhosphopantothenoylcysteine synthetase0.173
Pink1PTEN-induced putative kinase 10.169
Actnalpha actinin0.151
Drp1Dynamin related protein 10.143
ncdnon-claret disjunctional0.134
Grip128CG9201 gene product from transcript CG9201-RB0.126
stmAstambha A0.116
Poc1Proteome of centrioles 10.112
MarfMitochondrial assembly regulatory factor0.111
marsCG17064 gene product from transcript CG17064-RB0.111
Zasp52Z band alternatively spliced PDZ-motif protein 520.101
endoAendophilin A0.101
ifcinfertile crescent0.100
Psf1CG9187 gene product from transcript CG9187-RA0.095
Klp3AKinesin-like protein at 3A0.094
mod(mdg4)modifier of mdg40.088
par-6CG5884 gene product from transcript CG5884-RA0.088
Mlc2Myosin light chain 20.087
ewgerect wing0.087
Mo25CG4083 gene product from transcript CG4083-RA0.082
Nup44ANucleoporin 44A0.080
MicalMolecule interacting with CasL0.080
Rae1CG9862 gene product from transcript CG9862-RA0.080
nudECG8104 gene product from transcript CG8104-RB0.078
Sop2Suppressor of profilin 20.074
Grip75CG6176 gene product from transcript CG6176-RA0.072
G-oalpha47AG protein oalpha 47A0.071
CG5741CG5741 gene product from transcript CG5741-RC0.070
Hsp83Heat shock protein 830.066
Act88FActin 88F0.065
Cenp-CCG31258 gene product from transcript CG31258-RA0.063
GluRIIAGlutamate receptor IIA0.063
opa1-likeoptic atrophy 1-like0.062
Syx7Syntaxin 70.061
ref(2)Prefractory to sigma P0.061
WASpCG1520 gene product from transcript CG1520-RA0.060
spd-2spindle defective 20.057
LaspCG3849 gene product from transcript CG3849-RB0.057
snRNP-U1-70Ksmall ribonucleoprotein particle U1 subunit 70K0.056
eIF4G2eukaryotic translation initiation factor 4G20.056
Rbp9RNA-binding protein 90.055
rtGEFrho-type guanine exchange factor0.055
Cep135CG17081 gene product from transcript CG17081-RB0.053
ChcClathrin heavy chain0.053
MrtfMyocardin-related transcription factor0.052
chbchromosome bows0.052
Klp10ACG1453 gene product from transcript CG1453-RA0.052
Tom34Translocase of outer membrane 340.051
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ACTG1actin, gamma 10.327
ACTBactin, beta0.082
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.064
TRAF6TNF receptor-associated factor 60.054
TPM2tropomyosin 2 (beta)0.049
MYH9myosin, heavy chain 9, non-muscle0.047
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.043
SRSF2serine/arginine-rich splicing factor 20.043
TEX11testis expressed 110.042
CDK2cyclin-dependent kinase 20.041
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.041
ITGB4integrin, beta 40.041
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.039
FLNAfilamin A, alpha0.039
TPM1tropomyosin 1 (alpha)0.039
KIF1Bkinesin family member 1B0.036
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.035
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.033
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.032
SQSTM1sequestosome 10.030
TPM4tropomyosin 40.030
ANKRD28ankyrin repeat domain 280.028
CORO1Ccoronin, actin binding protein, 1C0.026
CENPJcentromere protein J0.025
PDLIM7PDZ and LIM domain 7 (enigma)0.024
IRAK2interleukin-1 receptor-associated kinase 20.024
TRIM63tripartite motif containing 630.023
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.023
CKS2CDC28 protein kinase regulatory subunit 20.023
HNRNPMheterogeneous nuclear ribonucleoprotein M0.022
EXOC1exocyst complex component 10.021
CCNA2cyclin A20.021
RBM8ARNA binding motif protein 8A0.021
DISC1disrupted in schizophrenia 10.019
SASS6spindle assembly 6 homolog (C. elegans)0.019
FAM190Bfamily with sequence similarity 190, member B0.019
EIF4A3eukaryotic translation initiation factor 4A30.019
EID1EP300 interacting inhibitor of differentiation 10.018
ACTN1actinin, alpha 10.018
RFX1regulatory factor X, 1 (influences HLA class II expression)0.018
NXF1nuclear RNA export factor 10.018
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.017
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.017
GLIS2GLIS family zinc finger 20.017
SCP2sterol carrier protein 20.017
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.017
MAPRE1microtubule-associated protein, RP/EB family, member 10.016
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.016
ZC3H12Azinc finger CCCH-type containing 12A0.016
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.016
ATP13A2ATPase type 13A20.016
LMNAlamin A/C0.016
KIF20Akinesin family member 20A0.016
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.015
RIPK3receptor-interacting serine-threonine kinase 30.015
TRA2Btransformer 2 beta homolog (Drosophila)0.015
PELI3pellino homolog 3 (Drosophila)0.015
IRAK3interleukin-1 receptor-associated kinase 30.015
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.015
CDK1cyclin-dependent kinase 10.015
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.014
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.014
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.014
FUNDC2FUN14 domain containing 20.014
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.014
MARK2MAP/microtubule affinity-regulating kinase 20.013
TAGLN2transgelin 20.013
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.013
SRSF3serine/arginine-rich splicing factor 30.013
SRSF10serine/arginine-rich splicing factor 100.013
ADRBK1adrenergic, beta, receptor kinase 10.013
CD14CD14 molecule0.013
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.013
CKS1BCDC28 protein kinase regulatory subunit 1B0.012
HNRNPA0heterogeneous nuclear ribonucleoprotein A00.012
ACTA1actin, alpha 1, skeletal muscle0.012
GNB5guanine nucleotide binding protein (G protein), beta 50.012
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.012
EXOC7exocyst complex component 70.012
KIF23kinesin family member 230.012
CBFBcore-binding factor, beta subunit0.012
SPTBN1spectrin, beta, non-erythrocytic 10.012
CENPEcentromere protein E, 312kDa0.012
APCadenomatous polyposis coli0.012
FUSfused in sarcoma0.012
MYD88myeloid differentiation primary response gene (88)0.012
TNIKTRAF2 and NCK interacting kinase0.012
EXOC2exocyst complex component 20.011
INADLInaD-like (Drosophila)0.011
CAV1caveolin 1, caveolae protein, 22kDa0.011
SNAP23synaptosomal-associated protein, 23kDa0.011
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.011
CNN2calponin 20.011
IRAK1interleukin-1 receptor-associated kinase 10.011
SMAD9SMAD family member 90.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cry2cryptochrome 2 (photolyase-like)0.988
Arntlaryl hydrocarbon receptor nuclear translocator-like0.883
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.867
Anlnanillin, actin binding protein0.810
Clockcircadian locomotor output cycles kaput0.777
Cdk1cyclin-dependent kinase 10.772
Kif20akinesin family member 20A0.681
Traf6TNF receptor-associated factor 60.656
Arpc4actin related protein 2/3 complex, subunit 40.582
Actr3ARP3 actin-related protein 3 homolog (yeast)0.460
Ccna2cyclin A20.458
Srsf1serine/arginine-rich splicing factor 10.457
Hmmrhyaluronan mediated motility receptor (RHAMM)0.454
Hmgb2high mobility group box 20.436
Pfn1profilin 10.419
Birc5baculoviral IAP repeat-containing 50.416
Dclk1doublecortin-like kinase 10.399
Tfdp1transcription factor Dp 10.384
Smc4structural maintenance of chromosomes 40.358
Racgap1Rac GTPase-activating protein 10.357
Cdkn3cyclin-dependent kinase inhibitor 30.347
Per3period homolog 3 (Drosophila)0.347
2500003M10RikRIKEN cDNA 2500003M10 gene0.333
Ccnb2cyclin B20.329
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.326
Ctnnb1catenin (cadherin associated protein), beta 10.325
Trim63tripartite motif-containing 630.312
Cry1cryptochrome 1 (photolyase-like)0.309
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.300
Kif22kinesin family member 220.274
Tra2btransformer 2 beta homolog (Drosophila)0.265
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.252
Itgb1integrin beta 1 (fibronectin receptor beta)0.234
Cdca8cell division cycle associated 80.224
Macf1microtubule-actin crosslinking factor 10.214
Top2atopoisomerase (DNA) II alpha0.205
Tubb5tubulin, beta 50.201
Csnk1ecasein kinase 1, epsilon0.195
Usp2ubiquitin specific peptidase 20.193
Fgfbp1fibroblast growth factor binding protein 10.190
Tra2atransformer 2 alpha homolog (Drosophila)0.190
Ect2ect2 oncogene0.186
Mki67antigen identified by monoclonal antibody Ki 670.184
Btrcbeta-transducin repeat containing protein0.177
Cks2CDC28 protein kinase regulatory subunit 20.173
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.163
Rac1RAS-related C3 botulinum substrate 10.158
Lbrlamin B receptor0.156
Lrrk2leucine-rich repeat kinase 20.155
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.154
C330027C09RikRIKEN cDNA C330027C09 gene0.152
Trim55tripartite motif-containing 550.150
Clasp1CLIP associating protein 10.146
Pdlim5PDZ and LIM domain 50.145
Capza1capping protein (actin filament) muscle Z-line, alpha 10.144
Nr2e1nuclear receptor subfamily 2, group E, member 10.136
Stx7syntaxin 70.135
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.135
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.132
Wdr1WD repeat domain 10.130
Smc2structural maintenance of chromosomes 20.129
Sept7septin 70.125
Gnb1guanine nucleotide binding protein (G protein), beta 10.125
Srsf10serine/arginine-rich splicing factor 100.121
Kif23kinesin family member 230.121
Ccdc99coiled-coil domain containing 990.119
Csrp1cysteine and glycine-rich protein 10.117
Shc3src homology 2 domain-containing transforming protein C30.111
Per2period homolog 2 (Drosophila)0.110
H2afxH2A histone family, member X0.108
Hn1hematological and neurological expressed sequence 10.106
Pcnaproliferating cell nuclear antigen0.104
Capzbcapping protein (actin filament) muscle Z-line, beta0.103
Cep55centrosomal protein 550.100
Bdnfbrain derived neurotrophic factor0.099
Gsk3bglycogen synthase kinase 3 beta0.099
Prc1protein regulator of cytokinesis 10.098
Thoc4THO complex 40.098
TardbpTAR DNA binding protein0.093
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.093
Kif4kinesin family member 40.092
Tceb1transcription elongation factor B (SIII), polypeptide 10.092
Irak4interleukin-1 receptor-associated kinase 40.089
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.088
Trp63transformation related protein 630.088
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.087
Trim59tripartite motif-containing 590.087
RbmxrtRNA binding motif protein, X chromosome retrogene0.087
Cltcclathrin, heavy polypeptide (Hc)0.086
Aurkaaurora kinase A0.084
Ilkintegrin linked kinase0.083
Tacc3transforming, acidic coiled-coil containing protein 30.080
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.079
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.078
Slc25a24solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 240.078
Dtnadystrobrevin alpha0.075
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.072
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.023