The network for 'negative regulation of protein complex disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein complex disassembly

Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.

NameDescriptionProbabilityFunc Analog Organism
CAP2Cap2p0.243
GBP2Gbp2p0.157
BOI1Boi1p0.155
KAR9Kar9p0.136
ABP1Abp1p0.109
CLB3Clb3p0.092
MYO5Myo5p0.091
BMH1Bmh1p0.075
SRV2Srv2p0.065
VIK1Vik1p0.050
CLB1Clb1p0.047
CIK1Cik1p0.044
BIK1Bik1p0.043
CDC6Cdc6p0.043
CIN8Cin8p0.043
GYL1Gyl1p0.040
ASE1Ase1p0.038
ENT3Ent3p0.033
KEL1Kel1p0.031
BNI1Bni1p0.030
TWF1Twf1p0.029
AIR1Air1p0.029
ARC40Arc40p0.029
ACM1Acm1p0.027
CDC24Cdc24p0.026
KAR3Kar3p0.025
DAM1Dam1p0.025
KIP1Kip1p0.024
YFR016Chypothetical protein0.022
BBC1Bbc1p0.022
BRN1Brn1p0.022
LAS17Las17p0.021
YPL014Whypothetical protein0.021
BMH2Bmh2p0.020
CLB4Clb4p0.020
LSB1Lsb1p0.020
DYN1Dyn1p0.020
DYN3Dyn3p0.019
CDC14Cdc14p0.019
NIS1Nis1p0.018
CLB6Clb6p0.018
SRD1Srd1p0.018
YLR264C-Ahypothetical protein0.018
YPR1Ypr1p0.018
YTA6Yta6p0.018
GLC7Glc7p0.018
SLI15Sli15p0.018
AIM21Aim21p0.017
CKS1Cks1p0.017
ORC6Orc6p0.017
HST3Hst3p0.017
KCC4Kcc4p0.017
LEU2Leu2p0.016
STB1Stb1p0.016
YOL038C-Ahypothetical protein0.016
ARP10Arp10p0.016
YLR162Whypothetical protein0.016
ASK1Ask1p0.015
SPL2Spl2p0.015
MEX67Mex67p0.015
BZZ1Bzz1p0.015
SKM1Skm1p0.015
CDC28Cdc28p0.015
MF(ALPHA)2Mf(alpha)2p0.015
SLK19Slk19p0.015
HOHop0.015
NDD1Ndd1p0.015
BIM1Bim1p0.015
ARG8Arg8p0.015
FIR1Fir1p0.014
MER1Mer1p0.014
NUD1Nud1p0.014
SGN1Sgn1p0.014
PHM6Phm6p0.014
HXT3Hxt3p0.014
MF(ALPHA)1Mf(alpha)1p0.013
YGL015Chypothetical protein0.013
YBR013Chypothetical protein0.013
YAR068Whypothetical protein0.013
ADH2Adh2p0.013
CAK1Cak1p0.013
ZPS1Zps1p0.013
GDI1Gdi1p0.013
SIC1Sic1p0.013
SPR6Spr6p0.013
ARE2Are2p0.013
THP2Thp2p0.013
KIP3Kip3p0.013
CPD1Cpd1p0.013
TYE7Tye7p0.013
ATP6Atp6p0.013
SAC6Sac6p0.013
HPF1Hpf1p0.013
YNL058Chypothetical protein0.012
YLR042Chypothetical protein0.012
SCP1Scp1p0.012
SPS4Sps4p0.012
PFY1Pfy1p0.012
SPC29Spc29p0.012
YPR157Whypothetical protein0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
DetDeterin0.913
exo84CG6095 gene product from transcript CG6095-RA0.887
brubrunelleschi0.754
diadiaphanous0.732
Klp67AKinesin-like protein at 67A0.667
CG32038CG32038 gene product from transcript CG32038-RA0.603
aspabnormal spindle0.562
alpha-Specalpha Spectrin0.560
tefteflon0.459
Dhc64CDynein heavy chain 64C0.290
sec8CG2095 gene product from transcript CG2095-RA0.244
vibvibrator0.229
marsCG17064 gene product from transcript CG17064-RB0.225
vasvasa0.212
gwlgreatwall0.206
nebnebbish0.170
slssallimus0.165
flwflapwing0.138
beta-Specbeta Spectrin0.124
sqhspaghetti squash0.123
Sas-4CG10061 gene product from transcript CG10061-RA0.117
mspsmini spindles0.116
wupAwings up A0.116
Spc25CG7242 gene product from transcript CG7242-RA0.111
poloCG12306 gene product from transcript CG12306-RA0.103
Pak3CG14895 gene product from transcript CG14895-RA0.098
CapsCalcium activated protein for secretion0.095
CG31224CG31224 gene product from transcript CG31224-RA0.090
ph-ppolyhomeotic proximal0.088
PpcsPhosphopantothenoylcysteine synthetase0.087
RfC4Replication factor C subunit 40.078
Orc2Origin recognition complex subunit 20.078
ballballchen0.077
Sop2Suppressor of profilin 20.076
austaustralin0.074
Unc-76CG3981 gene product from transcript CG3981-RB0.073
scrascraps0.073
Poc1Proteome of centrioles 10.073
aretarrest0.072
WASpCG1520 gene product from transcript CG1520-RA0.071
htshu li tai shao0.070
borrborealin-related0.066
bondjames bond0.062
ana3anastral spindle 30.062
eIF4G2eukaryotic translation initiation factor 4G20.060
Actnalpha actinin0.060
chercheerio0.055
Cp110CG14617 gene product from transcript CG14617-RB0.054
LaspCG3849 gene product from transcript CG3849-RB0.053
CG11329CG11329 gene product from transcript CG11329-RA0.053
flrflare0.052
CG9247CG9247 gene product from transcript CG9247-RA0.049
pcxpecanex0.046
Zasp52Z band alternatively spliced PDZ-motif protein 520.046
Zasp66Z band alternatively spliced PDZ-motif protein 660.045
sas-6spindle assembly abnormal 60.044
MarfMitochondrial assembly regulatory factor0.043
Act5CActin 5C0.043
DAAMDishevelled Associated Activator of Morphogenesis0.042
CG11299CG11299 gene product from transcript CG11299-RA0.041
Ino80CG31212 gene product from transcript CG31212-RA0.040
Vrp1Verprolin 10.040
Cog7CG31040 gene product from transcript CG31040-RA0.040
aslasterless0.040
MrtfMyocardin-related transcription factor0.039
Mlc2Myosin light chain 20.037
Cenp-CCG31258 gene product from transcript CG31258-RA0.036
LamCLamin C0.035
CG11033CG11033 gene product from transcript CG11033-RB0.035
ana2anastral spindle 20.034
mtrmmatrimony0.031
Arp66BActin-related protein 66B0.031
eglegalitarian0.030
DNApol-alpha60DNA polymerase alpha 60kD0.030
zpgzero population growth0.029
par-6CG5884 gene product from transcript CG5884-RA0.028
encencore0.028
lkb1CG9374 gene product from transcript CG9374-RJ0.027
salssarcomere length short0.027
cindrCIN85 and CD2AP orthologue0.027
Rae1CG9862 gene product from transcript CG9862-RA0.026
Gef26CG9491 gene product from transcript CG9491-RB0.026
synjsynaptojanin0.025
CG10260CG10260 gene product from transcript CG10260-RB0.024
larpLa related protein0.024
cmetCENP-meta0.024
Ndc80CG9938 gene product from transcript CG9938-RA0.024
ncdnon-claret disjunctional0.023
CycB3Cyclin B30.023
CG14215CG14215 gene product from transcript CG14215-RA0.023
otuovarian tumor0.022
sec5CG8843 gene product from transcript CG8843-RA0.022
Grip75CG6176 gene product from transcript CG6176-RA0.021
nudECG8104 gene product from transcript CG8104-RB0.021
CG5674CG5674 gene product from transcript CG5674-RB0.020
stwlstonewall0.020
opa1-likeoptic atrophy 1-like0.020
Grip128CG9201 gene product from transcript CG9201-RB0.020
Cep135CG17081 gene product from transcript CG17081-RB0.020
taitaiman0.020
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
IRAK2interleukin-1 receptor-associated kinase 20.814
TPM2tropomyosin 2 (beta)0.506
MYH9myosin, heavy chain 9, non-muscle0.365
TRIM63tripartite motif containing 630.294
IRAK1interleukin-1 receptor-associated kinase 10.226
FLNAfilamin A, alpha0.223
RACGAP1Rac GTPase activating protein 10.214
ACTN1actinin, alpha 10.199
APCadenomatous polyposis coli0.198
TEX11testis expressed 110.189
MYD88myeloid differentiation primary response gene (88)0.170
PDLIM7PDZ and LIM domain 7 (enigma)0.164
SASS6spindle assembly 6 homolog (C. elegans)0.164
EXOC1exocyst complex component 10.142
TPM1tropomyosin 1 (alpha)0.125
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.124
MARK2MAP/microtubule affinity-regulating kinase 20.109
INCENPinner centromere protein antigens 135/155kDa0.102
TRAF6TNF receptor-associated factor 60.098
CKS2CDC28 protein kinase regulatory subunit 20.096
CDK2cyclin-dependent kinase 20.088
RIPK3receptor-interacting serine-threonine kinase 30.086
KIF1Bkinesin family member 1B0.085
HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H)0.083
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.081
PSEN2presenilin 2 (Alzheimer disease 4)0.080
ZYXzyxin0.080
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.078
FLNBfilamin B, beta0.077
RAD21RAD21 homolog (S. pombe)0.076
EXOC2exocyst complex component 20.075
GLIS2GLIS family zinc finger 20.071
TPM4tropomyosin 40.070
MYPNmyopalladin0.069
RFX1regulatory factor X, 1 (influences HLA class II expression)0.066
CCNB2cyclin B20.059
CNN2calponin 20.057
KIF20Akinesin family member 20A0.057
ANKRD28ankyrin repeat domain 280.055
CENPEcentromere protein E, 312kDa0.054
LBRlamin B receptor0.054
ADRBK1adrenergic, beta, receptor kinase 10.047
PELI3pellino homolog 3 (Drosophila)0.046
HABP4hyaluronan binding protein 40.045
XPO1exportin 1 (CRM1 homolog, yeast)0.044
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.043
STK3serine/threonine kinase 30.039
KIF23kinesin family member 230.038
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.037
CCNB1cyclin B10.037
PBKPDZ binding kinase0.034
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.033
TTNtitin0.033
GAS2L3growth arrest-specific 2 like 30.032
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.032
TNIP1TNFAIP3 interacting protein 10.031
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.030
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.030
LMNAlamin A/C0.030
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.030
IRAK3interleukin-1 receptor-associated kinase 30.030
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.030
TNFAIP3tumor necrosis factor, alpha-induced protein 30.030
BIRC5baculoviral IAP repeat containing 50.029
CDK1cyclin-dependent kinase 10.029
CORO1Ccoronin, actin binding protein, 1C0.028
CCDC85Acoiled-coil domain containing 85A0.027
MYL9myosin, light chain 9, regulatory0.027
SUFUsuppressor of fused homolog (Drosophila)0.027
DEKDEK oncogene0.024
HMGB2high mobility group box 20.024
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.024
CENPJcentromere protein J0.024
ERBB2IPerbb2 interacting protein0.023
EXOC7exocyst complex component 70.023
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.023
CD2APCD2-associated protein0.022
SVILsupervillin0.022
WASLWiskott-Aldrich syndrome-like0.022
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.022
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.022
KIF5Bkinesin family member 5B0.022
SQSTM1sequestosome 10.021
ACTA1actin, alpha 1, skeletal muscle0.020
KIF4Akinesin family member 4A0.020
ZRANB1zinc finger, RAN-binding domain containing 10.020
AGLamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase0.020
CKAP5cytoskeleton associated protein 50.019
CCNE1cyclin E10.019
GRB2growth factor receptor-bound protein 20.019
GPSM2G-protein signaling modulator 20.019
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.019
VCLvinculin0.019
NBR1neighbor of BRCA1 gene 10.018
TMPOthymopoietin0.018
HNRNPA0heterogeneous nuclear ribonucleoprotein A00.018
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.018
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.018
MYCBP2MYC binding protein 20.018
CYLDcylindromatosis (turban tumor syndrome)0.017
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cry2cryptochrome 2 (photolyase-like)0.998
Arntlaryl hydrocarbon receptor nuclear translocator-like0.980
Clockcircadian locomotor output cycles kaput0.954
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.871
Macf1microtubule-actin crosslinking factor 10.856
Actr3ARP3 actin-related protein 3 homolog (yeast)0.787
Arpc4actin related protein 2/3 complex, subunit 40.742
Wdr1WD repeat domain 10.732
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.676
Dclk1doublecortin-like kinase 10.651
Cry1cryptochrome 1 (photolyase-like)0.644
Anlnanillin, actin binding protein0.597
Usp2ubiquitin specific peptidase 20.586
Dcxdoublecortin0.481
Capzbcapping protein (actin filament) muscle Z-line, beta0.474
Nr2e1nuclear receptor subfamily 2, group E, member 10.439
Kif20akinesin family member 20A0.429
BrafBraf transforming gene0.423
Cdk1cyclin-dependent kinase 10.397
Trim63tripartite motif-containing 630.397
Pfn1profilin 10.280
Gnb2guanine nucleotide binding protein (G protein), beta 20.276
Clasp1CLIP associating protein 10.268
Hmmrhyaluronan mediated motility receptor (RHAMM)0.267
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.262
Csrp1cysteine and glycine-rich protein 10.258
Csnk1ecasein kinase 1, epsilon0.242
Ccna2cyclin A20.241
Leprleptin receptor0.238
2500003M10RikRIKEN cDNA 2500003M10 gene0.204
Trim55tripartite motif-containing 550.196
Smc4structural maintenance of chromosomes 40.184
Vaspvasodilator-stimulated phosphoprotein0.171
Lbrlamin B receptor0.169
Kif11kinesin family member 110.168
Racgap1Rac GTPase-activating protein 10.165
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.161
Btrcbeta-transducin repeat containing protein0.160
Shc3src homology 2 domain-containing transforming protein C30.151
Ctnnb1catenin (cadherin associated protein), beta 10.148
Ckap2cytoskeleton associated protein 20.143
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.137
Dbnldrebrin-like0.123
Prc1protein regulator of cytokinesis 10.118
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.117
Ppp4cprotein phosphatase 4, catalytic subunit0.115
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.115
Akt1thymoma viral proto-oncogene 10.109
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.108
Gnb1guanine nucleotide binding protein (G protein), beta 10.108
Birc5baculoviral IAP repeat-containing 50.103
Rb1retinoblastoma 10.100
Itgb1integrin beta 1 (fibronectin receptor beta)0.099
Tfdp1transcription factor Dp 10.099
Traf6TNF receptor-associated factor 60.098
Mstnmyostatin0.098
Anapc2anaphase promoting complex subunit 20.096
Fgf14fibroblast growth factor 140.091
Cltcclathrin, heavy polypeptide (Hc)0.090
Fam49bfamily with sequence similarity 49, member B0.088
Smc2structural maintenance of chromosomes 20.086
Mki67antigen identified by monoclonal antibody Ki 670.086
Dckdeoxycytidine kinase0.083
Ect2ect2 oncogene0.083
Arhgap1Rho GTPase activating protein 10.082
Sgcdsarcoglycan, delta (dystrophin-associated glycoprotein)0.081
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.079
Bzw1basic leucine zipper and W2 domains 10.072
Smad3MAD homolog 3 (Drosophila)0.072
Sept7septin 70.072
Abi1abl-interactor 10.071
Mapre1microtubule-associated protein, RP/EB family, member 10.071
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.071
Spna2spectrin alpha 20.070
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.069
Fgfbp1fibroblast growth factor binding protein 10.067
Actr2ARP2 actin-related protein 2 homolog (yeast)0.064
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.062
Depdc1aDEP domain containing 1a0.062
Rhoaras homolog gene family, member A0.060
Tefthyrotroph embryonic factor0.060
Pgrprogesterone receptor0.059
Myo1cmyosin IC0.058
Hnrnpmheterogeneous nuclear ribonucleoprotein M0.057
Trp53transformation related protein 530.057
Tuba1atubulin, alpha 1A0.057
Rac1RAS-related C3 botulinum substrate 10.055
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.054
Gipc1GIPC PDZ domain containing family, member 10.054
Dtnadystrobrevin alpha0.054
Tubb5tubulin, beta 50.053
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.053
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.052
Lmnalamin A0.050
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.050
Wdr82WD repeat domain containing 820.049
Top2atopoisomerase (DNA) II alpha0.049
Hnrnph2heterogeneous nuclear ribonucleoprotein H20.048
Slc25a24solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 240.048
Ilkintegrin linked kinase0.046
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.043
Actr3ARP3 actin-related protein 3 homolog (yeast)0.033
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.028
Acta2smooth muscle alpha-actin0.026
Mapre1microtubule-associated protein, RP/EB family, member 10.024
Taglntransgelin0.017
Actbactin, beta0.011