The network for 'trabecula formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trabecula formation

The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.943
col1a2collagen, type I, alpha 20.621
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.445
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.186
wnt11rwingless-type MMTV integration site family, member 11, related0.150
wnt10awingless-type MMTV integration site family, member 10a0.125
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.097
postnperiostin, osteoblast specific factor0.095
col5a2lcollagen, type V, alpha 2-like0.081
col12a1collagen, type XII, alpha 10.078
tbx1T-box 10.055
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.054
nrg1neuregulin 10.054
cx43connexin 430.052
matn4matrilin 40.051
dlx4adistal-less homeobox gene 4a0.050
flt4fms-related tyrosine kinase 40.050
pdgfrlplatelet-derived growth factor receptor-like0.048
ripk2receptor-interacting serine-threonine kinase 20.048
dctdopachrome tautomerase0.048
angptl2angiopoietin-like 20.046
col6a2collagen, type VI, alpha 20.045
acta2actin, alpha 2, smooth muscle, aorta0.045
gdf6bgrowth differentiation factor 6b0.045
sparcsecreted acidic cysteine rich glycoprotein0.041
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.038
runx1runt-related transcription factor 10.037
card14caspase recruitment domain family, member 140.036
foxd3forkhead box D30.035
msxdmuscle segment homeobox D0.035
wnt3awingless-type MMTV integration site family, member 3A0.034
aplnraapelin receptor a0.034
arap3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.033
fbn2bfibrillin 2b0.033
restRE1-silencing transcription factor0.032
myf6myogenic factor 60.030
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.030
ptk6aPTK6 protein tyrosine kinase 6a0.030
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.030
mitfamicrophthalmia-associated transcription factor a0.029
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.029
ventventral expressed homeobox0.029
ephb4aeph receptor B4a0.029
wnt2bbwingless-type MMTV integration site family, member 2Bb0.029
pmp22aperipheral myelin protein 22a0.028
hsp90a.1heat shock protein 90-alpha 10.028
bmp2abone morphogenetic protein 2a0.028
snapc1bsmall nuclear RNA activating complex, polypeptide 1b0.027
LOC555739serine/threonine-protein kinase LMTK1-like0.027
col6a3collagen, type VI, alpha 30.027
tgfbitransforming growth factor, beta-induced0.026
tie1endothelium-specific receptor tyrosine kinase 10.026
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.026
mtpmicrosomal triglyceride transfer protein0.026
styk1serine/threonine/tyrosine kinase 10.025
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.025
nr6a1anuclear receptor subfamily 6, group A, member 1a0.024
fzd5frizzled homolog 50.024
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.024
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.023
efnb2aephrin B2a0.023
lef1lymphocyte enhancer binding factor 10.023
ihhaIndian hedgehog homolog a0.023
col7a1lcollagen type VII alpha 1-like0.023
ntn2netrin 20.022
egfl6EGF-like-domain, multiple 60.022
gpr126G protein-coupled receptor 1260.022
tnnt2atroponin T2a, cardiac0.022
sox7SRY-box containing gene 70.021
hhexhematopoietically expressed homeobox0.021
bnc2basonuclin 20.021
hspa12bheat shock protein 12B0.021
lrrc17leucine rich repeat containing 170.021
relv-rel reticuloendotheliosis viral oncogene homolog0.020
wnt4awingless-type MMTV integration site family, member 4a0.020
smyd1bSET and MYND domain containing 1b0.020
col1a1bcollagen, type I, alpha 1b0.020
sema3dsemaphorin 3d0.020
dab1adisabled homolog 1a (Drosophila)0.020
spna2spectrin alpha 20.019
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.019
fanclFanconi anemia, complementation group L0.018
ppargperoxisome proliferator activated receptor gamma0.018
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.018
aldh1a2aldehyde dehydrogenase 1 family, member A20.018
olfml3bolfactomedin-like 3b0.018
zbtb4zinc finger and BTB domain containing 40.018
cotl1coactosin-like 1 (Dictyostelium)0.018
actc1aactin, alpha, cardiac muscle 1a0.018
vsg1vessel-specific 10.018
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.128
TGFB1transforming growth factor, beta 10.113
ACVR1Bactivin A receptor, type IB0.066
MKL1megakaryoblastic leukemia (translocation) 10.066
TBX5T-box 50.060
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.055
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.036
ANGPT1angiopoietin 10.029
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.028
EPAS1endothelial PAS domain protein 10.027
TIMP2TIMP metallopeptidase inhibitor 20.025
GATA4GATA binding protein 40.024
CARM1coactivator-associated arginine methyltransferase 10.023
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.022
MYOGmyogenin (myogenic factor 4)0.021
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.020
EGLN3egl nine homolog 3 (C. elegans)0.018
PBRM1polybromo 10.017
ARandrogen receptor0.016
THBS2thrombospondin 20.015
TGFBR1transforming growth factor, beta receptor 10.014
ARID1AAT rich interactive domain 1A (SWI-like)0.013
THBS1thrombospondin 10.013
MSX1msh homeobox 10.012
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.012
ITGA7integrin, alpha 70.012
CFL1cofilin 1 (non-muscle)0.011
IGFBP3insulin-like growth factor binding protein 30.011
MKL2MKL/myocardin-like 20.011
ADAM12ADAM metallopeptidase domain 120.011
SP1Sp1 transcription factor0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loxlysyl oxidase0.950
Ror2receptor tyrosine kinase-like orphan receptor 20.926
Fgf8fibroblast growth factor 80.643
Foxc2forkhead box C20.635
Nos3nitric oxide synthase 3, endothelial cell0.592
Col1a1collagen, type I, alpha 10.575
Hand2heart and neural crest derivatives expressed transcript 20.492
Hand1heart and neural crest derivatives expressed transcript 10.466
Gdnfglial cell line derived neurotrophic factor0.465
Shhsonic hedgehog0.455
Sfrp2secreted frizzled-related protein 20.438
Dkk1dickkopf homolog 1 (Xenopus laevis)0.426
Col1a2collagen, type I, alpha 20.416
Fgfr2fibroblast growth factor receptor 20.393
Col5a2collagen, type V, alpha 20.380
Foxc1forkhead box C10.353
Bmp4bone morphogenetic protein 40.288
Hoxa13homeobox A130.269
Hey1hairy/enhancer-of-split related with YRPW motif 10.244
Col6a3collagen, type VI, alpha 30.242
Epas1endothelial PAS domain protein 10.224
Gata4GATA binding protein 40.223
Col5a1collagen, type V, alpha 10.223
Col6a2collagen, type VI, alpha 20.216
Gpc3glypican 30.215
Gdf5growth differentiation factor 50.212
Twist2twist homolog 2 (Drosophila)0.211
Prrx2paired related homeobox 20.208
Wnt3awingless-related MMTV integration site 3A0.208
Nkx6-1NK6 homeobox 10.204
Col3a1collagen, type III, alpha 10.201
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.198
Kdrkinase insert domain protein receptor0.197
Lhx1LIM homeobox protein 10.177
Mmp2matrix metallopeptidase 20.169
Thbs2thrombospondin 20.153
Hoxa11homeobox A110.152
Col6a1collagen, type VI, alpha 10.144
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.142
Adamts2a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20.142
Efnb2ephrin B20.137
Fgf5fibroblast growth factor 50.131
Barx1BarH-like homeobox 10.125
Gata6GATA binding protein 60.115
Tbx1T-box 10.111
Sox9SRY-box containing gene 90.111
Col14a1collagen, type XIV, alpha 10.111
Tgfb2transforming growth factor, beta 20.110
Fgf18fibroblast growth factor 180.107
Col16a1collagen, type XVI, alpha 10.106
Ctskcathepsin K0.101
Dlx5distal-less homeobox 50.101
Gli2GLI-Kruppel family member GLI20.101
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.101
Lama4laminin, alpha 40.099
Gli3GLI-Kruppel family member GLI30.098
Pax2paired box gene 20.097
Col15a1collagen, type XV, alpha 10.097
Pax8paired box gene 80.096
Wnt11wingless-related MMTV integration site 110.091
Ntf3neurotrophin 30.090
Bmp7bone morphogenetic protein 70.087
Srpxsushi-repeat-containing protein0.087
Arid1bAT rich interactive domain 1B (SWI-like)0.086
Cd248CD248 antigen, endosialin0.085
Twist1twist homolog 1 (Drosophila)0.084
Cilp2cartilage intermediate layer protein 20.084
Hoxd11homeobox D110.083
Pax3paired box gene 30.083
Gja3gap junction protein, alpha 30.083
Postnperiostin, osteoblast specific factor0.082
Fstl1follistatin-like 10.081
Cxcl12chemokine (C-X-C motif) ligand 120.079
Hey2hairy/enhancer-of-split related with YRPW motif 20.077
Alx3aristaless-like homeobox 30.076
Sox18SRY-box containing gene 180.076
Jag1jagged 10.073
Wnt10bwingless related MMTV integration site 10b0.072
Cav1caveolin 1, caveolae protein0.072
Htra3HtrA serine peptidase 30.072
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.070
Foxe1forkhead box E10.070
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.069
Prrx1paired related homeobox 10.068
Ptrfpolymerase I and transcript release factor0.067
Tbx15T-box 150.067
Fgfr3fibroblast growth factor receptor 30.066
Pax1paired box gene 10.066
Cdx1caudal type homeobox 10.064
Crlf1cytokine receptor-like factor 10.062
Efna4ephrin A40.062
Pcsk5proprotein convertase subtilisin/kexin type 50.062
Foxf2forkhead box F20.061
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism