The network for 'progesterone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

progesterone biosynthetic process

The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lhcgrluteinizing hormone/choriogonadotropin receptor0.938
Mc2rmelanocortin 2 receptor0.502
Nr5a1nuclear receptor subfamily 5, group A, member 10.222
Mep1ameprin 1 alpha0.159
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.120
Akr1c21aldo-keto reductase family 1, member C210.112
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.099
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.094
Starsteroidogenic acute regulatory protein0.093
Aqp8aquaporin 80.090
Acsm2acyl-CoA synthetase medium-chain family member 20.083
Akr1c6aldo-keto reductase family 1, member C60.081
Aadacarylacetamide deacetylase (esterase)0.076
Hsdl2hydroxysteroid dehydrogenase like 20.076
Slc12a1solute carrier family 12, member 10.061
4931406C07RikRIKEN cDNA 4931406C07 gene0.057
Chpt1choline phosphotransferase 10.054
Hao2hydroxyacid oxidase 20.053
Hoxa10homeobox A100.051
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.050
Otcornithine transcarbamylase0.046
Hgdhomogentisate 1, 2-dioxygenase0.046
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.044
Adh4alcohol dehydrogenase 4 (class II), pi polypeptide0.041
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.039
Rdh7retinol dehydrogenase 70.035
Pik3c2gphosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide0.035
Aldh6a1aldehyde dehydrogenase family 6, subfamily A10.035
Phyhphytanoyl-CoA hydroxylase0.034
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.033
Nr1i3nuclear receptor subfamily 1, group I, member 30.032
Lypla1lysophospholipase 10.031
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.031
Fbp1fructose bisphosphatase 10.029
G6pcglucose-6-phosphatase, catalytic0.029
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.029
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.027
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.026
Apohapolipoprotein H0.026
C9complement component 90.026
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.025
Cps1carbamoyl-phosphate synthetase 10.025
Timd2T-cell immunoglobulin and mucin domain containing 20.024
Prl7a1prolactin family 7, subfamily a, member 10.024
F13bcoagulation factor XIII, beta subunit0.024
Uoxurate oxidase0.023
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.023
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.023
Upp2uridine phosphorylase 20.023
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.022
Sult1b1sulfotransferase family 1B, member 10.021
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.021
Acsm3acyl-CoA synthetase medium-chain family member 30.020
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.019
Nr5a2nuclear receptor subfamily 5, group A, member 20.019
Svaseminal vesicle antigen0.018
Cyp2j5cytochrome P450, family 2, subfamily j, polypeptide 50.018
Car1carbonic anhydrase 10.017
Aldobaldolase B, fructose-bisphosphate0.017
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.017
Nr0b1nuclear receptor subfamily 0, group B, member 10.017
Muc13mucin 13, epithelial transmembrane0.017
BC013529cDNA sequence BC0135290.017
G6pc2glucose-6-phosphatase, catalytic, 20.017
Slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.017
Ces1gcarboxylesterase 1G0.016
Mbl2mannose-binding lectin (protein C) 20.016
Ces3acarboxylesterase 3A0.016
Arandrogen receptor0.016
Slc17a1solute carrier family 17 (sodium phosphate), member 10.015
Necap2NECAP endocytosis associated 20.015
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.015
Tnp1transition protein 10.015
Dram2VDNA-damage regulated autophagy modulator 20.015
Clrn3clarin 30.015
Tdo2tryptophan 2,3-dioxygenase0.015
1700074P13RikRIKEN cDNA 1700074P13 gene0.015
Acat1acetyl-Coenzyme A acetyltransferase 10.014
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.014
Pahphenylalanine hydroxylase0.014
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.014
Acad11acyl-Coenzyme A dehydrogenase family, member 110.014
Apobapolipoprotein B0.014
Vmn1r51vomeronasal 1 receptor 510.014
Slc25a20solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 200.014
Rab9RAB9, member RAS oncogene family0.014
Slc26a1solute carrier family 26 (sulfate transporter), member 10.014
Serpina5serine (or cysteine) peptidase inhibitor, clade A, member 50.014
F9coagulation factor IX0.014
Ugt2b34UDP glucuronosyltransferase 2 family, polypeptide B340.013
Syap1synapse associated protein 10.013
Hrsp12heat-responsive protein 120.013
Cst8cystatin 8 (cystatin-related epididymal spermatogenic)0.013
Klkb1kallikrein B, plasma 10.013
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.013
Csn1s2acasein alpha s2-like A0.013
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.013
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Lhcgrluteinizing hormone/choriogonadotropin receptor0.424
Gabarapl2GABA(A) receptor-associated protein like 20.148
Hibadh3-hydroxyisobutyrate dehydrogenase0.145
Akr1c18aldo-keto reductase family 1, member C180.129
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.098
Starsteroidogenic acute regulatory protein0.074
Rup2urinary protein 20.067
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.064
Cox6ccytochrome c oxidase, subunit VIc0.061
Prss3protease, serine, 30.055
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.054
Abhd14babhydrolase domain containing 14b0.053
Pla2g16phospholipase A2, group XVI0.051
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.048
Nlrp6NLR family, pyrin domain containing 60.046
Hes2hairy and enhancer of split 2 (Drosophila)0.044
Prl7d1prolactin family 7, subfamily d, member 10.044
Fam108b1family with sequence similarity 108, member B10.041
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.039
Hrh2histamine receptor H 20.038
Gucy2fguanylate cyclase 2F0.037
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.037
Sisucrase-isomaltase (alpha-glucosidase)0.035
Smpxsmall muscle protein, X-linked0.033
Scgb2a1secretoglobin, family 2A, member 10.033
RGD1304731similar to RIKEN cDNA 5330437I02 gene0.032
Tspy1testis specific protein, Y-linked 10.032
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.031
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.029
Vom1r105vomeronasal 1 receptor 1050.028
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.028
Fcer1aFc fragment of IgE, high affinity I, receptor for; alpha polypeptide0.028
Mceemethylmalonyl CoA epimerase0.027
Slc22a25solute carrier family 22, member 250.027
Hoxb8homeo box B80.027
Aqp8aquaporin 80.025
Naglt1Na+ dependent glucose transporter 10.024
Chrna3cholinergic receptor, nicotinic, alpha 30.024
FaslgFas ligand (TNF superfamily, member 6)0.024
Apohapolipoprotein H (beta-2-glycoprotein I)0.024
Ppyr1pancreatic polypeptide receptor 10.023
Rln1relaxin 10.023
Hbg1hemoglobin, gamma A0.023
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.022
Hcrtr2hypocretin (orexin) receptor 20.022
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.022
Cyb5acytochrome b5 type A (microsomal)0.021
Spt1salivary protein 10.021
Clca4chloride channel accessory 40.021
RhagRh-associated glycoprotein0.021
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.020
Cubncubilin (intrinsic factor-cobalamin receptor)0.020
Atxn1ataxin 10.020
Eci2enoyl-Coenzyme A delta isomerase 20.020
Crisp1cysteine-rich secretory protein 10.020
Gpr150G protein-coupled receptor 1500.020
Hao2hydroxyacid oxidase 2 (long chain)0.019
Mybpc1myosin binding protein C, slow type0.019
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.018
Olr416olfactory receptor 4160.018
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.018
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.017
Pxmp2peroxisomal membrane protein 20.017
Csrp3cysteine and glycine-rich protein 30.017
Drd1adopamine receptor D1A0.017
ND4NADH dehydrogenase subunit 40.017
Cmblcarboxymethylenebutenolidase homolog (Pseudomonas)0.017
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.017
Gsta4glutathione S-transferase alpha 40.017
Fut1fucosyltransferase 10.017
Vipvasoactive intestinal peptide0.017
Svs5seminal vesicle secretory protein 50.016
Cgm4carcinoembryonic antigen gene family 40.016
Prl3c1Prolactin family 3, subfamily c, member 10.016
Odf1outer dense fiber of sperm tails 10.016
Chrna10cholinergic receptor, nicotinic, alpha 100.016
Ppardperoxisome proliferator-activated receptor delta0.016
Tacr2tachykinin receptor 20.016
Ucp1uncoupling protein 1 (mitochondrial, proton carrier)0.016
Lalbalactalbumin, alpha0.016
Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 10.015
Npffr2neuropeptide FF receptor 20.015
Atp2c2ATPase, Ca++ transporting, type 2C, member 20.015
Adkadenosine kinase0.015
Grik3glutamate receptor, ionotropic, kainate 30.014
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.014
Cd80Cd80 molecule0.014
Aldh6a1aldehyde dehydrogenase 6 family, member A10.014
Mettl7bmethyltransferase like 7B0.014
Pdhbpyruvate dehydrogenase (lipoamide) beta0.014
Vcsa2variable coding sequence A20.014
Zadh2zinc binding alcohol dehydrogenase, domain containing 20.013
Gcm1glial cells missing homolog 1 (Drosophila)0.013
Mamdc4MAM domain containing 40.013
Ompolfactory marker protein0.013
Gpx2glutathione peroxidase 20.013
Kcnk3potassium channel, subfamily K, member 30.013
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.013