The network for 'protein localization to endoplasmic reticulum' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein localization to endoplasmic reticulum

A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.

NameDescriptionProbabilityFunc Analog Organism
SEC63Sec63p1.000
KAR2Kar2p0.992
SEC62Sec62p0.989
SRP54Srp54p0.988
SPC1Spc1p0.979
GET1Get1p0.979
SGT2Sgt2p0.968
SRP14Srp14p0.957
SEC66Sec66p0.954
SPC2Spc2p0.946
SRP21Srp21p0.944
SSS1Sss1p0.932
ERP2Erp2p0.918
SBH1Sbh1p0.895
SEC65Sec65p0.817
ERV25Erv25p0.770
SEC61Sec61p0.749
SSA2Ssa2p0.698
LHS1Lhs1p0.650
GET3Get3p0.612
PMT1Pmt1p0.544
CAF130Caf130p0.494
SSH1Ssh1p0.482
ERP5Erp5p0.475
GET4Get4p0.474
SRP72Srp72p0.453
OST2Ost2p0.356
SAR1Sar1p0.322
SEC72Sec72p0.319
SCJ1Scj1p0.287
SEC11Sec11p0.261
HTA2Hta2p0.244
STI1Sti1p0.242
YDJ1Ydj1p0.235
GWT1Gwt1p0.215
JEM1Jem1p0.210
SIL1Sil1p0.198
ERJ5Erj5p0.186
BTN2Btn2p0.159
MDY2Mdy2p0.157
EGD2Egd2p0.141
EGD1Egd1p0.126
YPT7Ypt7p0.115
SSA1Ssa1p0.110
SVP26Svp26p0.101
VPS74Vps74p0.096
LCL2Lcl2p0.091
HOC1Hoc1p0.089
KEG1Keg1p0.083
YNL181Whypothetical protein0.077
GPI2Gpi2p0.073
RER1Rer1p0.065
SRP68Srp68p0.064
UBC4Ubc4p0.064
SIS1Sis1p0.064
ERO1Ero1p0.064
ERD2Erd2p0.061
CUE4Cue4p0.061
YPT32Ypt32p0.059
RPL15BRpl15bp0.058
VMA4Vma4p0.057
ERP4Erp4p0.057
SFB2Sfb2p0.056
SSA4Ssa4p0.054
YKL063Chypothetical protein0.051
MDM20Mdm20p0.050
YBT1Ybt1p0.050
ENA5Ena5p0.050
STE24Ste24p0.049
YLR126Chypothetical protein0.048
YJR011Chypothetical protein0.048
SPC3Spc3p0.048
GUK1Guk1p0.048
BAP3Bap3p0.047
RPB3Rpb3p0.045
ERP6Erp6p0.045
INP2Inp2p0.044
YLR264C-Ahypothetical protein0.043
SEC12Sec12p0.042
PRS2Prs2p0.041
MPD1Mpd1p0.040
CRP1Crp1p0.040
SRD1Srd1p0.040
PHO86Pho86p0.040
LEU2Leu2p0.038
ARG8Arg8p0.038
YIP3Yip3p0.038
ALG5Alg5p0.038
URA6Ura6p0.038
YRB1Yrb1p0.038
CUP1-1Cup1-1p0.037
VMA10Vma10p0.037
YOL038C-Ahypothetical protein0.037
YER140Whypothetical protein0.037
YNR021Whypothetical protein0.037
IOC3Ioc3p0.036
AHA1Aha1p0.036
YHB1Yhb1p0.035
SEC13Sec13p0.035
SED5Sed5p0.035
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ahcy-1Protein AHCY-10.459
pdi-1Protein PDI-10.380
hsp-4Protein HSP-40.296
chc-1Protein CHC-10.279
ribo-1Protein RIBO-10.273
CELE_Y57G11C.15Protein Y57G11C.150.258
pdi-3Protein PDI-30.247
ama-1Protein AMA-10.237
T01G9.2Protein T01G9.20.217
klp-7Protein KLP-70.175
pdi-2Protein PDI-20.150
stt-3Protein STT-30.112
cct-7Protein CCT-70.110
fkb-6Protein FKB-60.110
Y25C1A.5Protein Y25C1A.50.099
lron-10Protein LRON-100.097
trap-1Protein TRAP-10.091
T03F1.1Protein T03F1.10.090
vps-32.1Protein VPS-32.10.089
trap-3Protein TRAP-30.083
paa-1Protein PAA-10.069
pod-1Protein POD-10.066
pam-1Protein PAM-10.065
gck-1Protein GCK-10.063
nucb-1Protein NUCB-10.063
lap-2Protein LAP-20.062
cct-2Protein CCT-20.061
prp-8Protein PRP-80.054
ima-3Protein IMA-30.053
F41E6.9Protein F41E6.90.051
dnj-7Protein DNJ-70.049
tars-1Protein TARS-10.049
ccdc-47Protein CCDC-470.047
metr-1Protein METR-10.046
T14G8.3Protein T14G8.30.045
CELE_T03F6.3Protein T03F6.30.044
tsn-1Protein TSN-10.041
clic-1Protein CLIC-10.041
mthf-1Protein MTHF-10.040
C45G9.5Protein C45G9.50.039
math-33Protein MATH-330.039
eif-3.BProtein EIF-3.B0.038
C18E9.2Protein C18E9.20.038
crt-1Protein CRT-10.035
snrp-200Protein SNRP-2000.034
trap-4Protein TRAP-40.034
dnj-29Protein DNJ-290.033
dao-5Protein DAO-50.029
tbb-2Protein TBB-20.028
CELE_C08H9.2Protein C08H9.20.027
sams-4Protein SAMS-40.027
uso-1Protein USO-10.027
sti-1Protein STI-10.026
tfg-1Protein TFG-10.025
ostb-1Protein OSTB-10.025
dnj-12Protein DNJ-120.023
R148.3Protein R148.30.023
Y71F9AL.17Protein Y71F9AL.170.022
stc-1Protein STC-10.022
R07H5.8Protein R07H5.80.022
sec-23Protein SEC-230.021
gsp-1Protein GSP-10.021
dnj-16Protein DNJ-160.020
CELE_ZK637.14Protein ZK637.140.020
eif-3.JProtein EIF-3.J0.019
F39G3.3Protein F39G3.30.019
hsp-3Protein HSP-30.018
CELE_W03F9.10Protein W03F9.100.018
tag-320Protein TAG-3200.018
nra-4Protein NRA-40.017
ostd-1Protein OSTD-10.016
hsp-1Protein HSP-10.016
imp-2Protein IMP-20.016
sec-24.1Protein SEC-24.10.015
C30C11.4Protein C30C11.40.015
inf-1Protein INF-10.015
cdc-37Protein CDC-370.015
nmt-1Protein NMT-10.015
rap-2Protein RAP-20.015
lap-1Protein LAP-10.014
K07H8.10Protein K07H8.100.014
rpn-2Protein RPN-20.013
rab-39Protein RAB-390.013
hke-4.2Protein HKE-4.20.013
W08E3.2Protein W08E3.20.013
tkt-1Protein TKT-10.013
ZK686.3Protein ZK686.30.012
tag-131Protein TAG-1310.012
ubc-3Protein UBC-30.012
dnj-13Protein DNJ-130.011
nkat-3Protein NKAT-30.011
mbf-1Protein MBF-10.011
wip-1Protein WIP-10.011
rpn-12Protein RPN-120.011
CELE_C07D8.6Protein C07D8.60.011
cgt-3Protein CGT-30.011
npp-9Protein NPP-90.011
xrn-2Protein XRN-20.011
R12E2.13Protein R12E2.130.010
map-2Protein MAP-20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Surf4Surfeit 40.013
SppSignal peptide protease0.013
SrpRbetaSignal recognition particle receptor beta0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HSPA1Aheat shock 70kDa protein 1A0.943
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.931
HSPA1Bheat shock 70kDa protein 1B0.894
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.791
CANXcalnexin0.774
SURF4surfeit 40.452
BAG1BCL2-associated athanogene0.399
BAG3BCL2-associated athanogene 30.369
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.351
DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 10.337
DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 10.332
LAPTM5lysosomal protein transmembrane 50.267
TMEM173transmembrane protein 1730.229
DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 110.213
PTPN23protein tyrosine phosphatase, non-receptor type 230.210
PEX19peroxisomal biogenesis factor 190.207
GET4golgi to ER traffic protein 4 homolog (S. cerevisiae)0.195
BAG6BCL2-associated athanogene 60.187
LMAN1lectin, mannose-binding, 10.173
SPTBspectrin, beta, erythrocytic0.169
SEC61BSec61 beta subunit0.150
VAPAVAMP (vesicle-associated membrane protein)-associated protein A, 33kDa0.142
RSL24D1ribosomal L24 domain containing 10.122
PPIDpeptidylprolyl isomerase D0.121
DERL1Der1-like domain family, member 10.121
SSR1signal sequence receptor, alpha0.111
PEX13peroxisomal biogenesis factor 130.107
HSPH1heat shock 105kDa/110kDa protein 10.104
HSP90B1heat shock protein 90kDa beta (Grp94), member 10.096
RAB3GAP1RAB3 GTPase activating protein subunit 1 (catalytic)0.093
CREB3cAMP responsive element binding protein 30.090
ST13suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)0.090
OCRLoculocerebrorenal syndrome of Lowe0.089
RABIFRAB interacting factor0.086
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.085
SEC63SEC63 homolog (S. cerevisiae)0.081
RPN1ribophorin I0.077
NACAnascent polypeptide-associated complex alpha subunit0.073
ATF7IPactivating transcription factor 7 interacting protein0.068
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.064
EHD1EH-domain containing 10.063
PTPN12protein tyrosine phosphatase, non-receptor type 120.061
VAPBVAMP (vesicle-associated membrane protein)-associated protein B and C0.058
RAB3GAP2RAB3 GTPase activating protein subunit 2 (non-catalytic)0.057
UBQLN4ubiquilin 40.057
UBL4Aubiquitin-like 4A0.056
PPP6Cprotein phosphatase 6, catalytic subunit0.055
SAV1salvador homolog 1 (Drosophila)0.054
PPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme0.054
USP54ubiquitin specific peptidase 540.054
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.050
OSBPL9oxysterol binding protein-like 90.050
RPL36ALribosomal protein L36a-like0.050
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.046
RAI2retinoic acid induced 20.045
WWP1WW domain containing E3 ubiquitin protein ligase 10.044
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.044
PDCD6programmed cell death 60.043
BAG2BCL2-associated athanogene 20.041
SERP1stress-associated endoplasmic reticulum protein 10.040
SEL1Lsel-1 suppressor of lin-12-like (C. elegans)0.040
SEC61A1Sec61 alpha 1 subunit (S. cerevisiae)0.040
SH3GL2SH3-domain GRB2-like 20.038
RAB8ARAB8A, member RAS oncogene family0.036
ERBB2IPerbb2 interacting protein0.036
AKAP6A kinase (PRKA) anchor protein 60.034
SEC62SEC62 homolog (S. cerevisiae)0.034
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.032
ARL1ADP-ribosylation factor-like 10.032
GDI2GDP dissociation inhibitor 20.031
CDK17cyclin-dependent kinase 170.031
EIF3Eeukaryotic translation initiation factor 3, subunit E0.031
EPS15epidermal growth factor receptor pathway substrate 150.031
CNBPCCHC-type zinc finger, nucleic acid binding protein0.030
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 60.029
USP8ubiquitin specific peptidase 80.027
UTP14CUTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)0.027
GFPT1glutamine--fructose-6-phosphate transaminase 10.026
TBK1TANK-binding kinase 10.026
USO1USO1 vesicle docking protein homolog (yeast)0.025
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.025
LAMP1lysosomal-associated membrane protein 10.025
DPP8dipeptidyl-peptidase 80.025
SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 10.025
FIS1fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)0.024
SMAD2SMAD family member 20.024
SEPT7septin 70.023
MORF4L1mortality factor 4 like 10.022
TMED9transmembrane emp24 protein transport domain containing 90.021
MEOX2mesenchyme homeobox 20.021
EFEMP2EGF containing fibulin-like extracellular matrix protein 20.021
RPN2ribophorin II0.021
HYOU1hypoxia up-regulated 10.020
STX5syntaxin 50.020
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.019
ZMPSTE24zinc metallopeptidase (STE24 homolog, S. cerevisiae)0.019
PRKACBprotein kinase, cAMP-dependent, catalytic, beta0.018
PEX14peroxisomal biogenesis factor 140.018
ANTXR2anthrax toxin receptor 20.018
PTPLBprotein tyrosine phosphatase-like (proline instead of catalytic arginine), member b0.018
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.112
Ndufs8NADH dehydrogenase (ubiquinone) Fe-S protein 80.085
Uqcr11ubiquinol-cytochrome c reductase, complex III subunit XI0.074
Lsmd1LSM domain containing 10.064
Ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 70.062
Rpl38ribosomal protein L380.054
Atp5eATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit0.054
LOC499782similar to 60S ribosomal protein L120.054
LOC100361944hypothetical protein LOC1003619440.054
Ndufb2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 20.053
Cox5bcytochrome c oxidase subunit Vb0.053
Ndufb6NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 60.052
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.049
Atp5j2ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F20.049
Tomm7translocase of outer mitochondrial membrane 7 homolog (yeast)0.048
Mrpl54mitochondrial ribosomal protein L540.046
LOC688869similar to cytochrome c oxidase, subunit VIb polypeptide 10.046
Romo1reactive oxygen species modulator 10.046
Myeov2myeloma overexpressed 20.045
Ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)0.042
RGD1306917similar to RIKEN cDNA 2900010M230.042
Tomm6translocase of outer mitochondrial membrane 6 homolog (yeast)0.041
Ndufs6NADH dehydrogenase (ubiquinone) Fe-S protein 60.039
Timm8btranslocase of inner mitochondrial membrane 8 homolog b (yeast)0.038
Polr2gpolymerase (RNA) II (DNA directed) polypeptide G0.035
Smek2SMEK homolog 2, suppressor of mek1 (Dictyostelium)0.034
Rpl19ribosomal protein L190.033
Ndufc1NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 10.033
Erhenhancer of rudimentary homolog (Drosophila)0.032
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.032
Ndufb10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 100.031
Tceb2transcription elongation factor B (SIII), polypeptide 20.029
Mrps21mitochondrial ribosomal protein S210.028
Ndufs5NADH dehydrogenase (ubiquinone) Fe-S protein 50.027
CutacutA divalent cation tolerance homolog (E. coli)0.027
Rps2ribosomal protein S20.027
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.026
Cox6a1cytochrome c oxidase, subunit VIa, polypeptide 10.026
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.026
Myl6lmyosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like0.026
RGD1564058similar to cDNA sequence BC0564740.025
Pompproteasome maturation protein0.025
Ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.024
LOC687029similar to differentially expressed in B16F10 10.024
LOC100363539mitochondrial ribosomal protein L33-like0.024
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.023
Ndufb7NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 70.023
Usmg5up-regulated during skeletal muscle growth 5 homolog (mouse)0.023
Mrpl13mitochondrial ribosomal protein L130.022
Nedd8neural precursor cell expressed, developmentally down-regulated 80.022
Rpl35ribosomal protein L350.022
Cox7a2cytochrome c oxidase subunit VIIa polypeptide 20.021
Mrps16mitochondrial ribosomal protein S160.021
Btf3basic transcription factor 30.021
Ndufa3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 30.020
Mrps12mitochondrial ribosomal protein S120.020
Rpl41ribosomal protein L410.020
LOC100359995rCG63619-like0.020
Copecoatomer protein complex, subunit epsilon0.020
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.020
Phpt1phosphohistidine phosphatase 10.019
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.019
Cox7bcytochrome c oxidase subunit VIIb0.019
Ndufs3NADH dehydrogenase (ubiquinone) Fe-S protein 30.019
Mrps23mitochondrial ribosomal protein S230.019
RGD1565363similar to RIKEN cDNA 1110025L050.018
Rps10ribosomal protein S100.018
Cyc1cytochrome c-10.018
Dynlrb1dynein light chain roadblock-type 10.018
Ndufa11NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 110.018
Cox7ccytochrome c oxidase, subunit VIIc0.017
Ndufa1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10.017
Ppibpeptidylprolyl isomerase B0.017
Uqcrqubiquinol-cytochrome c reductase, complex III subunit VII0.017
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.017
Mrps28mitochondrial ribosomal protein S280.017
Eef1b2eukaryotic translation elongation factor 1 beta 20.017
Atp5jATP synthase, H+ transporting, mitochondrial F0 complex, subunit F60.017
Tmed2transmembrane emp24 domain trafficking protein 20.016
Sec61gSEC61, gamma subunit0.016
Sfrs18splicing factor, arginine/serine-rich 180.016
Pnnpinin, desmosome associated protein0.016
Ndufa12NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 120.016
Ndufc2NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 20.016
Gadd45gip1growth arrest and DNA-damage-inducible, gamma interacting protein 10.015
Hnrph1heterogeneous nuclear ribonucleoprotein H10.015
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.015
Atp5g1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)0.015
Rps21ribosomal protein S210.015
Sec61bSec61 beta subunit0.015
Prpf4bPRP4 pre-mRNA processing factor 4 homolog B (yeast)0.015
RGD1560220similar to homolog of yeast TIM14 isoform c0.015
Ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.015
Mrps34mitochondrial ribosomal protein S340.015
Rpl10aribosomal protein L10A0.014
LOC685322similar to ubiquinol-cytochrome c reductase complex 7.2kDa protein isoform b0.014
Cisd1CDGSH iron sulfur domain 10.014
Chchd1coiled-coil-helix-coiled-coil-helix domain containing 10.014
Rpl22ribosomal protein L220.014
Tra2btransformer 2 beta homolog (Drosophila)0.014