The network for 'regulation of transcription by chromatin organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription by chromatin organization

Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.

NameDescriptionProbabilityFunc Analog Organism
HHT1Hht1p0.776
RTF1Rtf1p0.330
ITC1Itc1p0.256
SGF73Sgf73p0.184
SPT16Spt16p0.140
SAS4Sas4p0.125
MIG2Mig2p0.125
ISW1Isw1p0.107
TRA1Tra1p0.106
HHO1Hho1p0.102
ADA2Ada2p0.099
MIG1Mig1p0.094
NRG1Nrg1p0.093
DLS1Dls1p0.093
BDF1Bdf1p0.090
POB3Pob3p0.089
HOS4Hos4p0.087
LEO1Leo1p0.084
RCO1Rco1p0.078
HHT2Hht2p0.073
BDF2Bdf2p0.072
SPT6Spt6p0.072
SPT5Spt5p0.071
NUP170Nup170p0.069
CHD1Chd1p0.061
SWI1Swi1p0.060
YKR075Chypothetical protein0.059
CKA1Cka1p0.058
SIN3Sin3p0.057
DPB2Dpb2p0.057
SAS5Sas5p0.055
YCL021W-Ahypothetical protein0.055
TAF12Taf12p0.053
VAC7Vac7p0.053
MIG3Mig3p0.052
HAL5Hal5p0.051
GAT2Gat2p0.051
CSR2Csr2p0.050
LYS5Lys5p0.050
YTA7Yta7p0.050
HHF2Hhf2p0.049
NTO1Nto1p0.046
SPT8Spt8p0.046
SET3Set3p0.046
HDA3Hda3p0.046
HTB2Htb2p0.044
NGG1Ngg1p0.043
SET2Set2p0.043
HAA1Haa1p0.040
CTR9Ctr9p0.040
MDN1Mdn1p0.039
YNG1Yng1p0.039
ROX1Rox1p0.038
OPI1Opi1p0.037
TIF4632Tif4632p0.037
MOT1Mot1p0.036
RIF1Rif1p0.035
SPT20Spt20p0.035
SNT1Snt1p0.035
HDA2Hda2p0.034
IOC4Ioc4p0.034
HST1Hst1p0.033
TMA22Tma22p0.033
SIW14Siw14p0.032
UBP14Ubp14p0.032
SIR2Sir2p0.032
HAL1Hal1p0.032
KIC1Kic1p0.032
HIR2Hir2p0.031
GIP2Gip2p0.031
BUD4Bud4p0.031
YKL187Chypothetical protein0.031
MBR1Mbr1p0.031
HXT3Hxt3p0.030
CUP9Cup9p0.030
PSH1Psh1p0.030
HOS3Hos3p0.030
RSC30Rsc30p0.029
CPR1Cpr1p0.029
NUP157Nup157p0.029
KEM1Kem1p0.028
SWR1Swr1p0.028
ZEO1Zeo1p0.028
ARP4Arp4p0.027
SIR3Sir3p0.027
MLC1Mlc1p0.027
RLM1Rlm1p0.027
POG1Pog1p0.026
CYC8Cyc8p0.026
ATG29Atg29p0.026
RIM8Rim8p0.026
IRC23Irc23p0.026
YPL014Whypothetical protein0.026
YIL151Chypothetical protein0.025
GIS4Gis4p0.025
CKB1Ckb1p0.025
RAP1Rap1p0.025
EPL1Epl1p0.025
MMR1Mmr1p0.024
TAF6Taf6p0.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Jarid2CG3654 gene product from transcript CG3654-RD0.221
CTCFCG8591 gene product from transcript CG8591-RA0.175
Su(var)2-10Suppressor of variegation 2-100.120
Mcm2Minichromosome maintenance 20.098
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.094
Nup98Nucleoporin 980.086
Su(var)3-3Suppressor of variegation 3-30.080
MBD-likeCG8208 gene product from transcript CG8208-RA0.075
SuURSuppressor of Under-Replication0.071
Rpd3CG7471 gene product from transcript CG7471-RA0.064
pashapartner of drosha0.055
pr-set7CG3307 gene product from transcript CG3307-RC0.049
Grip84gamma-tubulin ring protein 840.043
Hel25EHelicase at 25E0.040
Acf1ATP-dependent chromatin assembly factor large subunit0.040
BEAF-32Boundary element-associated factor of 32kD0.039
DekCG5935 gene product from transcript CG5935-RA0.036
hklhook-like0.036
Top2Topoisomerase 20.034
E(var)3-9Enhancer of variegation 3-90.034
Suv4-20CG13363 gene product from transcript CG13363-RA0.033
Su(var)205Suppressor of variegation 2050.033
otuovarian tumor0.032
Su(var)3-7Suppressor of variegation 3-70.032
XNPCG4548 gene product from transcript CG4548-RA0.032
Sir2CG5216 gene product from transcript CG5216-RA0.032
Mi-2CG8103 gene product from transcript CG8103-RA0.030
spn-Espindle E0.028
pluplutonium0.027
Fs(2)KetFemale sterile (2) Ketel0.027
maelmaelstrom0.026
piwiCG6122 gene product from transcript CG6122-RA0.026
fs(2)ltoPP43female sterile (2) ltoPP430.026
SMC1CG6057 gene product from transcript CG6057-RA0.025
CG14438CG14438 gene product from transcript CG14438-RA0.025
pngpan gu0.023
stwlstonewall0.023
PPP4R2rProtein phosphatase 4 regulatory subunit 2-related protein0.021
chmchameau0.021
His2AvHistone H2A variant0.021
CG11137CG11137 gene product from transcript CG11137-RA0.020
asf1anti-silencing factor 10.020
AGO2Argonaute 20.019
mip120Myb-interacting protein 1200.019
Gef26CG9491 gene product from transcript CG9491-RB0.019
CyplCyclophilin-like0.019
dupdouble parked0.019
MEP-1CG1244 gene product from transcript CG1244-RG0.018
WRNexoWRN exonuclease0.018
trrtrithorax-related0.017
BG4CG12297 gene product from transcript CG12297-RA0.017
msl-3male-specific lethal 30.017
mus209mutagen-sensitive 2090.017
encencore0.017
iclnCG4924 gene product from transcript CG4924-RA0.016
CG31122CG31122 gene product from transcript CG31122-RA0.016
Gr28bGustatory receptor 28b0.016
HP4Heterochromatin protein 40.016
crmcramped0.016
ash1absent, small, or homeotic discs 10.016
Nup160Nucleoporin 1600.015
Mekk1CG7717 gene product from transcript CG7717-RB0.015
jumujumeau0.015
SMC2CG10212 gene product from transcript CG10212-RA0.015
Snm1CG10018 gene product from transcript CG10018-RA0.015
pzgputzig0.015
gktglaikit0.015
CG14183CG14183 gene product from transcript CG14183-RA0.015
CG7427CG7427 gene product from transcript CG7427-RA0.015
bgcnbenign gonial cell neoplasm0.014
Ulp1CG12359 gene product from transcript CG12359-RA0.014
CG7239CG7239 gene product from transcript CG7239-RA0.014
ird5immune response deficient 50.014
CG3125CG3125 gene product from transcript CG3125-RA0.014
CG13022CG13022 gene product from transcript CG13022-RB0.014
PGRP-LCPeptidoglycan recognition protein LC0.014
Df31Decondensation factor 310.014
rowrelative of woc0.014
RfC38Replication factor C 38kD subunit0.013
enokenoki mushroom0.013
Nf-YBNuclear factor Y-box B0.013
E(z)Enhancer of zeste0.013
Pgam5Phosphoglycerate mutase 50.013
Grip163CG5688 gene product from transcript CG5688-RA0.013
mofmales absent on the first0.013
Map60Microtubule-associated protein 600.013
rodrough deal0.013
dhddeadhead0.013
Kmn1kinetochore Mis12-Ndc80 network component 10.013
ph-dpolyhomeotic distal0.013
CG5098CG5098 gene product from transcript CG5098-RA0.012
CG6752CG6752 gene product from transcript CG6752-RA0.012
CG7713CG7713 gene product from transcript CG7713-RA0.012
eggeggless0.012
Hsp68Heat shock protein 680.012
atmsantimeros0.012
CG2931CG2931 gene product from transcript CG2931-RA0.012
CG6418CG6418 gene product from transcript CG6418-RB0.012
piepineapple eye0.012
SceSex combs extra0.012
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.872
NBNnibrin0.715
CREBBPCREB binding protein0.597
CBX5chromobox homolog 50.543
EP300E1A binding protein p3000.494
TRRAPtransformation/transcription domain-associated protein0.456
MCM7minichromosome maintenance complex component 70.429
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.335
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.299
RB1retinoblastoma 10.240
RAD50RAD50 homolog (S. cerevisiae)0.229
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.227
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.209
SSRP1structure specific recognition protein 10.201
TGIF1TGFB-induced factor homeobox 10.196
HIST1H3Bhistone cluster 1, H3b0.168
LBRlamin B receptor0.154
WRNWerner syndrome, RecQ helicase-like0.135
ADNPactivity-dependent neuroprotector homeobox0.119
NRIP1nuclear receptor interacting protein 10.103
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.102
RAD21RAD21 homolog (S. pombe)0.102
CBX1chromobox homolog 10.101
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.099
ATXN7ataxin 70.093
PRRC2Cproline-rich coiled-coil 2C0.085
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.084
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.083
MCM2minichromosome maintenance complex component 20.081
CDK2cyclin-dependent kinase 20.080
RANBP2RAN binding protein 20.078
INCENPinner centromere protein antigens 135/155kDa0.077
BCLAF1BCL2-associated transcription factor 10.075
CREB1cAMP responsive element binding protein 10.070
USP22ubiquitin specific peptidase 220.068
CHRAC1chromatin accessibility complex 10.067
SMC1Astructural maintenance of chromosomes 1A0.065
RBBP4retinoblastoma binding protein 40.063
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.063
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.058
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.055
HIPK2homeodomain interacting protein kinase 20.053
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.052
MCM3minichromosome maintenance complex component 30.050
RBBP8retinoblastoma binding protein 80.050
KAT2BK(lysine) acetyltransferase 2B0.049
ORC6origin recognition complex, subunit 60.048
PMLpromyelocytic leukemia0.047
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.047
MBD1methyl-CpG binding domain protein 10.047
DAXXdeath-domain associated protein0.046
SUZ12suppressor of zeste 12 homolog (Drosophila)0.044
NCOA3nuclear receptor coactivator 30.043
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.040
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.038
MCMBPminichromosome maintenance complex binding protein0.038
TOPORStopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase0.037
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.035
SIN3ASIN3 homolog A, transcription regulator (yeast)0.033
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.033
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.032
APCadenomatous polyposis coli0.032
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.031
MDC1mediator of DNA-damage checkpoint 10.031
EEDembryonic ectoderm development0.030
PTPN4protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)0.029
DNMT1DNA (cytosine-5-)-methyltransferase 10.029
ARandrogen receptor0.028
NUP50nucleoporin 50kDa0.028
BAZ2Bbromodomain adjacent to zinc finger domain, 2B0.027
MCM4minichromosome maintenance complex component 40.027
TADA2Atranscriptional adaptor 2A0.027
FOXO3forkhead box O30.027
CDK6cyclin-dependent kinase 60.027
HDAC1histone deacetylase 10.026
NCOA1nuclear receptor coactivator 10.026
ADNP2ADNP homeobox 20.025
MORC3MORC family CW-type zinc finger 30.025
TAF15TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa0.025
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.025
RSF1remodeling and spacing factor 10.025
MIS12MIS12, MIND kinetochore complex component, homolog (S. pombe)0.025
H2AFVH2A histone family, member V0.025
POLE4polymerase (DNA-directed), epsilon 4 (p12 subunit)0.024
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.024
DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2)0.024
TADA3transcriptional adaptor 30.023
H3F3BH3 histone, family 3B (H3.3B)0.023
CRY1cryptochrome 1 (photolyase-like)0.023
CHAF1Achromatin assembly factor 1, subunit A (p150)0.023
SUV39H1suppressor of variegation 3-9 homolog 1 (Drosophila)0.022
MSH6mutS homolog 6 (E. coli)0.022
POGZpogo transposable element with ZNF domain0.021
CHEK2CHK2 checkpoint homolog (S. pombe)0.021
TOP1topoisomerase (DNA) I0.021
HMGXB4HMG box domain containing 40.021
ZEB1zinc finger E-box binding homeobox 10.020
NCOA6nuclear receptor coactivator 60.020
ANKRD17ankyrin repeat domain 170.020
H2AFXH2A histone family, member X0.020
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smc1astructural maintenance of chromosomes 1A0.984
Trim28tripartite motif-containing 280.798
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.754
Kdm2blysine (K)-specific demethylase 2B0.694
Trim24tripartite motif-containing 240.631
Srsf1serine/arginine-rich splicing factor 10.566
Timelesstimeless homolog (Drosophila)0.552
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.383
Rnf2ring finger protein 20.355
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.297
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.289
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.283
Cdt1chromatin licensing and DNA replication factor 10.253
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.235
Stag1stromal antigen 10.232
Rcc2regulator of chromosome condensation 20.218
Dnmt1DNA methyltransferase (cytosine-5) 10.215
Lig1ligase I, DNA, ATP-dependent0.213
Smc3structural maintenace of chromosomes 30.170
Casp8ap2caspase 8 associated protein 20.152
Mcm6minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)0.150
Suz12suppressor of zeste 12 homolog (Drosophila)0.134
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.132
Cbx5chromobox homolog 5 (Drosophila HP1a)0.120
Baz1abromodomain adjacent to zinc finger domain 1A0.108
Mecp2methyl CpG binding protein 20.092
Ep400E1A binding protein p4000.092
Pou5f1POU domain, class 5, transcription factor 10.091
Rif1Rap1 interacting factor 1 homolog (yeast)0.091
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.091
Thoc2THO complex 20.090
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.087
Cbx1chromobox homolog 1 (Drosophila HP1 beta)0.087
CtcfCCCTC-binding factor0.086
Rnpc3RNA-binding region (RNP1, RRM) containing 30.086
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.082
Wdr5WD repeat domain 50.082
Atxn7ataxin 70.078
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.077
Baz1bbromodomain adjacent to zinc finger domain, 1B0.076
E2f1E2F transcription factor 10.075
BcorBCL6 interacting corepressor0.073
Msl2male-specific lethal 2 homolog (Drosophila)0.073
Pcm1pericentriolar material 10.068
Polepolymerase (DNA directed), epsilon0.063
Bclaf1BCL2-associated transcription factor 10.062
Arid1bAT rich interactive domain 1B (SWI-like)0.062
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.061
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.060
Prim1DNA primase, p49 subunit0.059
Kdm1alysine (K)-specific demethylase 1A0.056
Rfc5replication factor C (activator 1) 50.055
Sae1SUMO1 activating enzyme subunit 10.054
Ppigpeptidyl-prolyl isomerase G (cyclophilin G)0.051
Ubap2ubiquitin-associated protein 20.051
Epc2enhancer of polycomb homolog 2 (Drosophila)0.051
Trraptransformation/transcription domain-associated protein0.050
Rsbn1rosbin, round spermatid basic protein 10.050
Smc6structural maintenance of chromosomes 60.050
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.047
Ythdc1YTH domain containing 10.047
Rb1retinoblastoma 10.045
Klhl24kelch-like 24 (Drosophila)0.045
Maelmaelstrom homolog (Drosophila)0.045
Cbx3chromobox homolog 3 (Drosophila HP1 gamma)0.045
Rrm1ribonucleotide reductase M10.043
Cdca5cell division cycle associated 50.043
Csnk2a1casein kinase 2, alpha 1 polypeptide0.042
Rbm26RNA binding motif protein 260.042
Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B10.041
Nup153nucleoporin 1530.041
Chaf1achromatin assembly factor 1, subunit A (p150)0.040
Hmgb1high mobility group box 10.040
Creb1cAMP responsive element binding protein 10.040
Rad21RAD21 homolog (S. pombe)0.040
Usp7ubiquitin specific peptidase 70.039
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.039
Rrm2ribonucleotide reductase M20.039
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.039
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.039
NanogNanog homeobox0.038
MgaMAX gene associated0.038
Hcfc1host cell factor C10.038
Brca2breast cancer 20.037
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.036
Dmap1DNA methyltransferase 1-associated protein 10.036
Cdkn1bcyclin-dependent kinase inhibitor 1B0.035
Mms22lMMS22-like, DNA repair protein0.034
L3mbtl2l(3)mbt-like 2 (Drosophila)0.034
Anapc5anaphase-promoting complex subunit 50.034
Sp1trans-acting transcription factor 10.033
MaxMax protein0.033
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.033
Ppargperoxisome proliferator activated receptor gamma0.032
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.032
Bod1lbiorientation of chromosomes in cell division 1-like0.030
Ing3inhibitor of growth family, member 30.029
Hellshelicase, lymphoid specific0.028
Cnot4CCR4-NOT transcription complex, subunit 40.028
Cdc73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.028
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism