The network for 'response to chemical' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to chemical

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

NameDescriptionProbabilityFunc Analog Organism
STE11Ste11p0.985
ATG1Atg1p0.928
STE4Ste4p0.909
PPH21Pph21p0.891
STE5Ste5p0.863
FUS3Fus3p0.829
SWE1Swe1p0.814
SSA1Ssa1p0.775
STE2Ste2p0.767
HOG1Hog1p0.766
HSP82Hsp82p0.765
BMH1Bmh1p0.745
RPN4Rpn4p0.742
STE20Ste20p0.738
FAR1Far1p0.735
TPK1Tpk1p0.731
CLA4Cla4p0.716
SLT2Slt2p0.716
GFA1Gfa1p0.675
AGA1Aga1p0.672
HSP104Hsp104p0.669
FAR11Far11p0.635
SNF2Snf2p0.630
UIP3Uip3p0.618
TSA2Tsa2p0.613
YAP1Yap1p0.610
AGA2Aga2p0.606
HSP42Hsp42p0.592
RIM101Rim101p0.588
CDC42Cdc42p0.579
CPR7Cpr7p0.558
RHO1Rho1p0.555
SOK2Sok2p0.543
BEM1Bem1p0.536
CLN3Cln3p0.535
SST2Sst2p0.534
FUS1Fus1p0.531
PFK26Pfk26p0.530
GLN3Gln3p0.522
MKS1Mks1p0.517
FIG2Fig2p0.512
RAV1Rav1p0.510
GRX4Grx4p0.502
MSG5Msg5p0.500
STE7Ste7p0.496
MFA1Mfa1p0.480
DOT6Dot6p0.478
SKS1Sks1p0.476
PTC1Ptc1p0.473
BCY1Bcy1p0.468
XBP1Xbp1p0.466
RPG1Rpg1p0.464
ARP8Arp8p0.462
AFT1Aft1p0.457
AHC1Ahc1p0.456
ROM2Rom2p0.456
SET1Set1p0.449
STE18Ste18p0.448
SSK1Ssk1p0.446
SNT1Snt1p0.444
URE2Ure2p0.442
MIG1Mig1p0.437
SAM1Sam1p0.435
ULP2Ulp2p0.430
TOR1Tor1p0.430
LSM1Lsm1p0.427
TFS1Tfs1p0.426
RRI1Rri1p0.422
YAK1Yak1p0.421
PDR12Pdr12p0.417
MSN4Msn4p0.415
CRZ1Crz1p0.409
MGA2Mga2p0.403
CNB1Cnb1p0.401
UGA1Uga1p0.396
GRR1Grr1p0.395
RTG3Rtg3p0.394
UBA1Uba1p0.393
GIS1Gis1p0.393
SCH9Sch9p0.390
GCD7Gcd7p0.390
VPS20Vps20p0.386
USA1Usa1p0.383
FAR3Far3p0.382
VPS62Vps62p0.379
BDH1Bdh1p0.378
GPA1Gpa1p0.375
ADR1Adr1p0.372
SEC66Sec66p0.371
KSS1Kss1p0.368
GLR1Glr1p0.367
TPK2Tpk2p0.365
STE50Ste50p0.364
HXT2Hxt2p0.362
CUP9Cup9p0.361
ISW2Isw2p0.356
OTU1Otu1p0.356
SHP1Shp1p0.354
VAC7Vac7p0.352
FIG4Fig4p0.351
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
vab-3Protein VAB-30.994
unc-9Protein UNC-90.914
egl-18Protein EGL-180.799
tag-320Protein TAG-3200.754
acs-4Protein ACS-40.736
par-5Protein PAR-50.735
egg-6Protein EGG-60.723
nhr-67Protein NHR-670.708
ida-1Protein IDA-10.705
fln-2Protein FLN-20.687
unc-42Protein UNC-420.675
pkg-1Protein PKG-10.652
pry-1Protein PRY-10.651
unc-70Protein UNC-700.649
che-2Protein CHE-20.648
lin-25Protein LIN-250.631
fkh-2Protein FKH-20.630
hlh-2Protein HLH-20.621
osm-5Protein OSM-50.581
unc-104Protein UNC-1040.580
CELE_T05E11.3Protein T05E11.30.577
hsp-3Protein HSP-30.576
vab-10Protein VAB-100.569
unc-57Protein UNC-570.561
bar-1Protein BAR-10.559
let-418Protein LET-4180.555
unc-73Protein UNC-730.545
egl-8Protein EGL-80.537
sax-3Protein SAX-30.516
cki-2Protein CKI-20.516
egl-46Protein EGL-460.513
jnk-1Protein JNK-10.502
pde-4Protein PDE-40.499
let-2Protein LET-20.493
CELE_Y57A10A.13Protein Y57A10A.130.486
hum-5Protein HUM-50.481
cam-1Protein CAM-10.480
unc-86Protein UNC-860.474
fan-1Protein FAN-10.466
soc-2Protein SOC-20.462
deb-1Protein DEB-10.461
abl-1Protein ABL-10.460
hlh-1Protein HLH-10.458
lin-5Protein LIN-50.457
odr-3Protein ODR-30.453
rfp-1Protein RFP-10.453
ZK686.3Protein ZK686.30.449
mls-2Protein MLS-20.446
eps-8Protein EPS-80.442
daf-11Protein DAF-110.434
mbk-2Protein MBK-20.431
sdz-28Protein SDZ-280.430
sgt-1Protein SGT-10.430
let-60Protein LET-600.426
itr-1Protein ITR-10.425
K10D6.4Protein K10D6.40.424
zip-7Protein ZIP-70.422
egl-5Protein EGL-50.421
mat-3Protein MAT-30.416
cdc-37Protein CDC-370.415
rig-6Protein RIG-60.415
hsp-4Protein HSP-40.412
vab-8Protein VAB-80.412
che-3Protein CHE-30.411
somi-1Protein SOMI-10.410
sym-4Protein SYM-40.409
atg-2Protein ATG-20.407
T28F4.1Protein T28F4.10.403
unc-7Protein UNC-70.397
ldb-1Protein LDB-10.397
hsp-16.1Protein HSP-16.10.393
apr-1Protein APR-10.390
egl-13Protein EGL-130.389
fln-1Protein FLN-10.388
gpb-2Protein GPB-20.386
T10B11.2Protein T10B11.20.386
tbb-4Protein TBB-40.382
unc-62Protein UNC-620.380
sng-1Protein SNG-10.380
npr-1Protein NPR-10.375
unc-32Protein UNC-320.372
lin-17Protein LIN-170.371
shn-1Protein SHN-10.369
ceh-20Protein CEH-200.366
cid-1Protein CID-10.362
clh-5Protein CLH-50.360
syg-1Protein SYG-10.359
mig-2Protein MIG-20.358
unc-98Protein UNC-980.357
vit-6Protein VIT-60.357
hsp-16.41Protein HSP-16.410.355
wrk-1Protein WRK-10.355
pha-4Protein PHA-40.354
unc-83Protein UNC-830.351
ung-1Protein UNG-10.347
egl-15Protein EGL-150.347
F33H2.3Protein F33H2.30.346
cdf-1Protein CDF-10.343
mab-5Protein MAB-50.343
zen-4Protein ZEN-40.341
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf3fibroblast growth factor 31.000
pitx3paired-like homeodomain transcription factor 30.996
ndr2nodal-related 20.996
wnt8bwingless-type MMTV integration site family, member 8b0.980
pax6apaired box gene 6a0.976
fgfr1afibroblast growth factor receptor 1a0.973
pax2apaired box gene 2a0.966
shhasonic hedgehog a0.965
lef1lymphocyte enhancer binding factor 10.938
gli2aGLI-Kruppel family member GLI2a0.936
dzip1DAZ interacting protein 10.933
chdchordin0.928
otpaorthopedia homolog a0.925
prnprs3prion protein, related sequence 30.920
wnt1wingless-type MMTV integration site family, member 10.913
osr1odd-skipped related 1 (Drosophila)0.911
gcm2glial cells missing homolog 2 (Drosophila)0.911
egr1early growth response 10.907
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.905
dag1dystroglycan 10.895
vasavasa homolog0.892
bocbrother of CDO0.891
shhbsonic hedgehog b0.886
sox9aSRY-box containing gene 9a0.883
ptgs2aprostaglandin-endoperoxide synthase 2a0.883
tbx20T-box 200.883
efnb2aephrin B2a0.879
dlx5adistal-less homeobox gene 5a0.875
robo3roundabout homolog 30.873
dharmadharma0.862
col1a1acollagen, type I, alpha 1a0.856
fabp11afatty acid binding protein 11a0.845
lft1lefty10.842
foxn4forkhead box N40.835
piwil1piwi-like 1 (Drosophila)0.832
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.831
igf1rainsulin-like growth factor 1a receptor0.831
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.824
etv5bets variant 5b0.822
fgfr2fibroblast growth factor receptor 20.822
axin1axin 10.822
bmperBMP binding endothelial regulator0.817
pomcaproopiomelanocortin a0.808
foxp2forkhead box P20.807
tal1T-cell acute lymphocytic leukemia 10.805
cxcr4achemokine (C-X-C motif) receptor 4a0.803
olfm2olfactomedin 20.792
pax8paired box gene 80.791
trpv6transient receptor potential cation channel, subfamily V, member 60.791
dab1adisabled homolog 1a (Drosophila)0.781
mstnbmyostatin b0.776
gli1GLI-Kruppel family member 10.773
wnt11wingless-type MMTV integration site family, member 110.765
prmt1protein arginine methyltransferase 10.764
dmddystrophin0.762
robo2roundabout homolog 20.760
arxaristaless related homeobox0.756
cdx4caudal type homeo box transcription factor 40.754
sox32SRY-box containing gene 320.753
il17rdinterleukin 17 receptor D0.737
dab1bdisabled homolog 1b (Drosophila)0.737
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.718
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.717
arnt2aryl hydrocarbon receptor nuclear translocator 20.714
tp73tumor protein p730.714
tram1translocating chain-associating membrane protein 10.710
hspa5heat shock protein 50.709
fgf8afibroblast growth factor 8 a0.708
spry4sprouty (Drosophila) homolog 40.706
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.702
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.692
nrp2bneuropilin 2b0.686
dlx2adistal-less homeobox gene 2a0.686
jag2jagged 20.685
foxi3aforkhead box I3a0.683
lamc1laminin, gamma 10.679
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.678
sulf1sulfatase 10.676
nkx3.2NK3 homeobox 20.673
cdh1cadherin 1, epithelial0.662
sox4aSRY-box containing gene 4a0.661
alcambactivated leukocyte cell adhesion molecule b0.660
gng3guanine nucleotide binding protein (G protein), gamma 30.657
nf1aneurofibromin 1a0.656
gro2groucho 20.656
hoxc1ahomeo box C1a0.656
mycbp2MYC binding protein 20.652
gpiaglucose phosphate isomerase a0.647
phox2apaired-like homeobox 2a0.638
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.638
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.637
ascl1aachaete-scute complex-like 1a (Drosophila)0.629
pou4f2POU domain, class 4, transcription factor 20.627
tgfb1atransforming growth factor, beta 1a0.627
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.626
nadl1.2neural adhesion molecule L1.20.624
prdm1aPR domain containing 1a, with ZNF domain0.623
rx3retinal homeobox gene 30.623
esrrgaestrogen-related receptor gamma a0.623
ptmaaprothymosin, alpha a0.622
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism