The network for 'cellular amino acid catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

NameDescriptionProbabilityFunc Analog Organism
ARG81Arg81p0.781
ASP3-4Asp3-4p0.722
ASP3-3Asp3-3p0.676
ASP3-2Asp3-2p0.663
ARO9Aro9p0.571
ASP3-1Asp3-1p0.567
UGA1Uga1p0.520
HSP60Hsp60p0.430
GCV1Gcv1p0.371
PUT1Put1p0.301
SHM2Shm2p0.275
BAT2Bat2p0.264
PYC1Pyc1p0.246
ADH1Adh1p0.244
GND1Gnd1p0.236
HOM6Hom6p0.230
ADH3Adh3p0.220
YDR391Chypothetical protein0.216
STR2Str2p0.214
SCC4Scc4p0.191
PDC5Pdc5p0.181
YJR149Whypothetical protein0.166
TRR1Trr1p0.162
LAT1Lat1p0.156
LSC2Lsc2p0.147
ADH2Adh2p0.144
YMR226Chypothetical protein0.138
TRM5Trm5p0.136
CIT2Cit2p0.115
DUG2Dug2p0.114
FBA1Fba1p0.112
HEM13Hem13p0.111
PDC1Pdc1p0.105
GDH1Gdh1p0.103
LAP4Lap4p0.103
GCV2Gcv2p0.102
YDL157Chypothetical protein0.102
PHO11Pho11p0.101
PLB1Plb1p0.100
MCH4Mch4p0.098
BNA1Bna1p0.097
MET3Met3p0.096
SUL1Sul1p0.094
MVD1Mvd1p0.086
ARO1Aro1p0.085
YHR112Chypothetical protein0.082
YAP5Yap5p0.081
ALD2Ald2p0.080
SPE3Spe3p0.079
ECM38Ecm38p0.079
DUG1Dug1p0.076
BAT1Bat1p0.076
ALD3Ald3p0.075
YKL023Whypothetical protein0.074
DUR1,2Dur1,2p0.073
ENO2Eno2p0.071
YDL086Whypothetical protein0.067
SVF1Svf1p0.065
CMK2Cmk2p0.065
TUB3Tub3p0.065
FAA2Faa2p0.064
YOR302Whypothetical protein0.063
NTG1Ntg1p0.063
SAM2Sam2p0.061
SEC53Sec53p0.061
CPS1Cps1p0.061
ACC1Acc1p0.061
SES1Ses1p0.061
PUT2Put2p0.060
AVT7Avt7p0.060
TEA1Tea1p0.060
YJL213Whypothetical protein0.058
FMS1Fms1p0.058
RRT2Rrt2p0.055
IRC20Irc20p0.055
VPS62Vps62p0.055
HOR2Hor2p0.053
DAK1Dak1p0.050
CRP1Crp1p0.050
ZWF1Zwf1p0.050
LEU4Leu4p0.050
VMA13Vma13p0.050
GRX8Grx8p0.050
HLR1Hlr1p0.049
INO1Ino1p0.049
MET28Met28p0.048
XDJ1Xdj1p0.048
STB6Stb6p0.047
OPT1Opt1p0.047
FIT2Fit2p0.047
ARG8Arg8p0.046
LEU2Leu2p0.046
YLR162Whypothetical protein0.046
GCV3Gcv3p0.045
DUG3Dug3p0.044
CAR1Car1p0.044
DDR48Ddr48p0.044
HXT3Hxt3p0.043
YLR264C-Ahypothetical protein0.043
YGR237Chypothetical protein0.043
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GGT1gamma-glutamyltransferase 10.940
HADHhydroxyacyl-CoA dehydrogenase0.908
CASP9caspase 9, apoptosis-related cysteine peptidase0.903
NOSTRINnitric oxide synthase trafficker0.903
TUBGCP4tubulin, gamma complex associated protein 40.822
ALDOBaldolase B, fructose-bisphosphate0.622
XIAPX-linked inhibitor of apoptosis0.518
CASP3caspase 3, apoptosis-related cysteine peptidase0.504
C21orf33chromosome 21 open reading frame 330.499
YARStyrosyl-tRNA synthetase0.394
GCDHglutaryl-CoA dehydrogenase0.381
AARSalanyl-tRNA synthetase0.326
GGTLC1gamma-glutamyltransferase light chain 10.317
VAC14Vac14 homolog (S. cerevisiae)0.303
BCKDHBbranched chain keto acid dehydrogenase E1, beta polypeptide0.265
MARSmethionyl-tRNA synthetase0.204
TOM1L1target of myb1 (chicken)-like 10.196
MCCC1methylcrotonoyl-CoA carboxylase 1 (alpha)0.190
GARSglycyl-tRNA synthetase0.171
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.153
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.133
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.116
EPT1ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)0.097
GLUD1glutamate dehydrogenase 10.088
GGT2gamma-glutamyltransferase 20.088
ACADSBacyl-CoA dehydrogenase, short/branched chain0.083
GLUD2glutamate dehydrogenase 20.075
HIBADH3-hydroxyisobutyrate dehydrogenase0.074
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.073
HMGCL3-hydroxymethyl-3-methylglutaryl-CoA lyase0.072
PHGDHphosphoglycerate dehydrogenase0.067
MAP2K5mitogen-activated protein kinase kinase 50.063
ASNSasparagine synthetase (glutamine-hydrolyzing)0.062
LONP1lon peptidase 1, mitochondrial0.061
ALDH6A1aldehyde dehydrogenase 6 family, member A10.060
TMEM106Btransmembrane protein 106B0.058
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.054
DLG2discs, large homolog 2 (Drosophila)0.052
GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase0.052
ALDH4A1aldehyde dehydrogenase 4 family, member A10.051
BCKDHAbranched chain keto acid dehydrogenase E1, alpha polypeptide0.048
GPIglucose-6-phosphate isomerase0.048
NNTnicotinamide nucleotide transhydrogenase0.047
SARSseryl-tRNA synthetase0.044
IARSisoleucyl-tRNA synthetase0.041
PSAT1phosphoserine aminotransferase 10.039
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.031
SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 150.031
CARScysteinyl-tRNA synthetase0.030
AHCYadenosylhomocysteinase0.030
ALDH3A2aldehyde dehydrogenase 3 family, member A20.030
TMEM97transmembrane protein 970.029
CPT2carnitine palmitoyltransferase 20.029
ECI2enoyl-CoA delta isomerase 20.028
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.028
DHTKD1dehydrogenase E1 and transketolase domain containing 10.027
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.027
PHYHphytanoyl-CoA 2-hydroxylase0.026
COQ9coenzyme Q9 homolog (S. cerevisiae)0.026
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.025
SORDsorbitol dehydrogenase0.025
NOS1APnitric oxide synthase 1 (neuronal) adaptor protein0.025
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit0.025
ECH1enoyl CoA hydratase 1, peroxisomal0.025
SLC22A7solute carrier family 22 (organic anion transporter), member 70.025
MASP2mannan-binding lectin serine peptidase 20.024
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.024
SUCLG2succinate-CoA ligase, GDP-forming, beta subunit0.024
HAX1HCLS1 associated protein X-10.024
CATcatalase0.024
DCXRdicarbonyl/L-xylulose reductase0.023
PCCBpropionyl CoA carboxylase, beta polypeptide0.023
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.023
PCYOX1prenylcysteine oxidase 10.022
IVDisovaleryl-CoA dehydrogenase0.022
APOC2apolipoprotein C-II0.022
SLC37A4solute carrier family 37 (glucose-6-phosphate transporter), member 40.022
CA5Acarbonic anhydrase VA, mitochondrial0.020
SUOXsulfite oxidase0.020
ALDH1L1aldehyde dehydrogenase 1 family, member L10.019
SLC28A1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.019
PEBP1phosphatidylethanolamine binding protein 10.019
SHMT1serine hydroxymethyltransferase 1 (soluble)0.018
PCpyruvate carboxylase0.018
AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)0.018
ACAD8acyl-CoA dehydrogenase family, member 80.018
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 20.018
BDH13-hydroxybutyrate dehydrogenase, type 10.017
ACADSacyl-CoA dehydrogenase, C-2 to C-3 short chain0.017
PON1paraoxonase 10.017
PNPOpyridoxamine 5'-phosphate oxidase0.017
BHMTbetaine--homocysteine S-methyltransferase0.016
SUPV3L1suppressor of var1, 3-like 1 (S. cerevisiae)0.016
EPHX2epoxide hydrolase 2, cytoplasmic0.015
NAMPTnicotinamide phosphoribosyltransferase0.015
HAAO3-hydroxyanthranilate 3,4-dioxygenase0.015
ABCC6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.015
BREbrain and reproductive organ-expressed (TNFRSF1A modulator)0.015
MCCC2methylcrotonoyl-CoA carboxylase 2 (beta)0.015
TRAP1TNF receptor-associated protein 10.015
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hibadh3-hydroxyisobutyrate dehydrogenase0.450
Mccc1methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)0.435
Ivdisovaleryl coenzyme A dehydrogenase0.328
Ak3adenylate kinase 30.306
Gabrdgamma-aminobutyric acid (GABA) A receptor, subunit delta0.288
Vdrvitamin D receptor0.285
Mutmethylmalonyl-Coenzyme A mutase0.218
Tdo2tryptophan 2,3-dioxygenase0.171
Thrathyroid hormone receptor alpha0.158
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.157
Srebf2sterol regulatory element binding factor 20.153
Dbtdihydrolipoamide branched chain transacylase E20.151
Mmp9matrix metallopeptidase 90.135
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.128
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.123
Acy1aminoacylase 10.117
Acad11acyl-Coenzyme A dehydrogenase family, member 110.117
Mccc2methylcrotonoyl-Coenzyme A carboxylase 2 (beta)0.115
Pxmp2peroxisomal membrane protein 20.110
Ncoa1nuclear receptor coactivator 10.104
Ccbl2cysteine conjugate-beta lyase 20.102
Lap3leucine aminopeptidase 30.099
Gstz1glutathione transferase zeta 1 (maleylacetoacetate isomerase)0.099
Mosc1MOCO sulphurase C-terminal domain containing 10.091
Ldlrlow density lipoprotein receptor0.089
Ptgs2prostaglandin-endoperoxide synthase 20.085
Nos1nitric oxide synthase 1, neuronal0.081
Nipsnap14-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)0.076
Ndrg2N-myc downstream regulated gene 20.074
Pipoxpipecolic acid oxidase0.074
Hgdhomogentisate 1, 2-dioxygenase0.074
Mdh1malate dehydrogenase 1, NAD (soluble)0.074
Plgplasminogen0.073
Atad3aATPase family, AAA domain containing 3A0.072
Glud1glutamate dehydrogenase 10.072
Gstk1glutathione S-transferase kappa 10.066
Dmgdhdimethylglycine dehydrogenase precursor0.065
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.064
Ifnginterferon gamma0.063
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.063
Pccbpropionyl Coenzyme A carboxylase, beta polypeptide0.062
Iydiodotyrosine deiodinase0.062
Itm2bintegral membrane protein 2B0.062
Adhfe1alcohol dehydrogenase, iron containing, 10.062
Ccl2chemokine (C-C motif) ligand 20.061
Vegfavascular endothelial growth factor A0.061
Ftcdformiminotransferase cyclodeaminase0.060
Pcxpyruvate carboxylase0.059
Acadsbacyl-Coenzyme A dehydrogenase, short/branched chain0.058
Gpld1glycosylphosphatidylinositol specific phospholipase D10.057
Gnmtglycine N-methyltransferase0.056
Tstthiosulfate sulfurtransferase, mitochondrial0.056
Agtr1aangiotensin II receptor, type 1a0.056
Aldh6a1aldehyde dehydrogenase family 6, subfamily A10.055
Sdsserine dehydratase0.054
Catcatalase0.053
Il10interleukin 100.052
Cbscystathionine beta-synthase0.052
S100a5S100 calcium binding protein A50.052
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.051
Klf15Kruppel-like factor 150.051
Slc25a15solute carrier family 25 (mitochondrial carrier ornithine transporter), member 150.050
Ttc36tetratricopeptide repeat domain 360.050
Gcdhglutaryl-Coenzyme A dehydrogenase0.049
Fgf1fibroblast growth factor 10.049
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.049
Abcd3ATP-binding cassette, sub-family D (ALD), member 30.047
Aadataminoadipate aminotransferase0.047
Aldh1l1aldehyde dehydrogenase 1 family, member L10.047
Nr1h4nuclear receptor subfamily 1, group H, member 40.047
Prlrprolactin receptor0.046
Pex7peroxisomal biogenesis factor 70.045
Ghrgrowth hormone receptor0.044
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.043
Acad8acyl-Coenzyme A dehydrogenase family, member 80.043
Suclg2succinate-Coenzyme A ligase, GDP-forming, beta subunit0.043
Pm20d1peptidase M20 domain containing 10.043
Ahcyl1S-adenosylhomocysteine hydrolase-like 10.041
Il6interleukin 60.041
Echdc3enoyl Coenzyme A hydratase domain containing 30.041
Gjb1gap junction protein, beta 10.041
Magmyelin-associated glycoprotein0.040
Slc25a5solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 50.040
Gphngephyrin0.039
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.039
Itih3inter-alpha trypsin inhibitor, heavy chain 30.038
Serpina1eserine (or cysteine) peptidase inhibitor, clade A, member 1E0.038
Acat1acetyl-Coenzyme A acetyltransferase 10.038
Ei24etoposide induced 2.4 mRNA0.038
Aldh7a1aldehyde dehydrogenase family 7, member A10.038
Azgp1alpha-2-glycoprotein 1, zinc0.038
Apoeapolipoprotein E0.038
Hrghistidine-rich glycoprotein0.037
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase0.037
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.036
Rmnd5arequired for meiotic nuclear division 5 homolog A (S. cerevisiae)0.036
Oatornithine aminotransferase0.036
Cps1carbamoyl-phosphate synthetase 10.036
Creb3l3cAMP responsive element binding protein 3-like 30.036
Gtf2ird1general transcription factor II I repeat domain-containing 10.036
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gcdhglutaryl-Coenzyme A dehydrogenase0.801
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.704
Adkadenosine kinase0.643
Glud1glutamate dehydrogenase 10.322
Adhfe1alcohol dehydrogenase, iron containing, 10.275
Mccc2methylcrotonoyl-Coenzyme A carboxylase 2 (beta)0.199
Ass1argininosuccinate synthetase 10.193
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.183
Pahphenylalanine hydroxylase0.182
Acy1aminoacylase 10.176
Aldh9a1aldehyde dehydrogenase 9 family, member A10.173
Gstm7glutathione S-transferase, mu 70.151
Suclg2succinate-CoA ligase, GDP-forming, beta subunit0.146
Ahcyadenosylhomocysteinase0.145
Pxmp2peroxisomal membrane protein 20.125
Cbscystathionine beta synthase0.118
Aldh1l1aldehyde dehydrogenase 1 family, member L10.095
Slco2a1solute carrier organic anion transporter family, member 2a10.093
Agxt2alanine-glyoxylate aminotransferase 20.092
Dhtkd1dehydrogenase E1 and transketolase domain containing 10.090
Fbp1fructose-1,6-bisphosphatase 10.088
Aldh2aldehyde dehydrogenase 2 family (mitochondrial)0.086
Bckdhbbranched chain keto acid dehydrogenase E1, beta polypeptide0.082
Gstk1glutathione S-transferase kappa 10.080
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.078
Keg1kidney expressed gene 10.074
Pccbpropionyl coenzyme A carboxylase, beta polypeptide0.074
Afpalpha-fetoprotein0.071
Dpysdihydropyrimidinase0.071
Acat1acetyl-coenzyme A acetyltransferase 10.070
Fgafibrinogen alpha chain0.070
Fahfumarylacetoacetate hydrolase0.070
Gnmtglycine N-methyltransferase0.068
Pccapropionyl-coenzyme A carboxylase, alpha polypeptide0.065
Tstthiosulfate sulfurtransferase0.065
Upb1ureidopropionase, beta0.062
Nfs1NFS1 nitrogen fixation 1 homolog (S. cerevisiae)0.062
Mipepmitochondrial intermediate peptidase0.060
Ivdisovaleryl coenzyme A dehydrogenase0.059
Hao2hydroxyacid oxidase 2 (long chain)0.058
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.056
Acsm2acyl-CoA synthetase medium-chain family member 20.053
Gstz1glutathione transferase zeta 10.053
Bhmtbetaine-homocysteine methyltransferase0.052
Abhd14babhydrolase domain containing 14b0.051
AktipAKT interacting protein0.050
Aldobaldolase B, fructose-bisphosphate0.050
Hrsp12heat-responsive protein 120.048
Dlstdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)0.047
Aadataminoadipate aminotransferase0.047
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.047
Haghhydroxyacyl glutathione hydrolase0.047
Josd2Josephin domain containing 20.046
Dhfrdihydrofolate reductase0.045
Rgnregucalcin (senescence marker protein-30)0.044
Ube4aubiquitination factor E4A (UFD2 homolog, yeast)0.043
Gulogulonolactone (L-) oxidase0.042
Dcxrdicarbonyl L-xylulose reductase0.041
Aldh7a1aldehyde dehydrogenase 7 family, member A10.041
Pgm1phosphoglucomutase 10.040
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.039
Gys2glycogen synthase 20.039
Klf15Kruppel-like factor 150.039
Mromaestro0.039
Aldh4a1aldehyde dehydrogenase 4 family, member A10.039
Alg2asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)0.038
Dio1deiodinase, iodothyronine, type I0.038
Acsl1acyl-CoA synthetase long-chain family member 10.037
Glsglutaminase0.037
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.037
Sfxn1sideroflexin 10.037
Gcgroup specific component0.036
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.034
Scp2sterol carrier protein 20.034
Cdo1cysteine dioxygenase, type I0.033
Hpd4-hydroxyphenylpyruvate dioxygenase0.033
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.033
Amacralpha-methylacyl-CoA racemase0.032
Azgp1alpha-2-glycoprotein 1, zinc-binding0.032
Sardhsarcosine dehydrogenase0.032
Stat4signal transducer and activator of transcription 40.031
Mtmr7myotubularin related protein 70.031
Adh1alcohol dehydrogenase 1 (class I)0.030
Nipsnap1nipsnap homolog 1 (C. elegans)0.030
Slc17a1solute carrier family 17 (sodium phosphate), member 10.030
Hsd17b11hydroxysteroid (17-beta) dehydrogenase 110.030
Cps1carbamoyl-phosphate synthetase 10.030
Slc25a13solute carrier family 25, member 13 (citrin)0.029
Khkketohexokinase0.029
Hspa9heat shock protein 90.029
St6gal1ST6 beta-galactosamide alpha-2,6-sialyltranferase 10.029
Pdk2pyruvate dehydrogenase kinase, isozyme 20.029
Ttc36tetratricopeptide repeat domain 360.028
Mat1amethionine adenosyltransferase I, alpha0.028
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.028
Aadacarylacetamide deacetylase (esterase)0.028
Car5acarbonic anhydrase 5a, mitochondrial0.028
Afmafamin0.028
Mosc2MOCO sulphurase C-terminal domain containing 20.027
Mutmethylmalonyl-Coenzyme A mutase0.027