The network for 'serine family amino acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

serine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.

NameDescriptionProbabilityFunc Analog Organism
SHM2Shm2p0.830
GCV3Gcv3p0.590
SER33Ser33p0.338
TRP5Trp5p0.263
SER3Ser3p0.261
GND1Gnd1p0.203
LAT1Lat1p0.199
ARO2Aro2p0.178
SUL1Sul1p0.150
GCV1Gcv1p0.120
MET3Met3p0.118
MTD1Mtd1p0.107
ALG13Alg13p0.100
GCV2Gcv2p0.098
THR1Thr1p0.093
DPS1Dps1p0.089
ADE12Ade12p0.088
FMP40Fmp40p0.088
PHO11Pho11p0.085
GUS1Gus1p0.079
PCL10Pcl10p0.079
MET2Met2p0.077
ERG13Erg13p0.076
BDH1Bdh1p0.071
ILV6Ilv6p0.069
FPR1Fpr1p0.068
NPL3Npl3p0.068
NMA2Nma2p0.066
ADE17Ade17p0.066
ASR1Asr1p0.066
MET22Met22p0.065
HOM3Hom3p0.064
RBK1Rbk1p0.063
CYS3Cys3p0.062
ASN1Asn1p0.057
SUL2Sul2p0.054
THR4Thr4p0.054
GCY1Gcy1p0.053
YGR054Whypothetical protein0.053
MCH4Mch4p0.051
PHO12Pho12p0.051
DLD3Dld3p0.049
LSC2Lsc2p0.049
PRM7Prm7p0.048
ADE3Ade3p0.048
GNP1Gnp1p0.048
ARO10Aro10p0.047
SER1Ser1p0.045
LEU2Leu2p0.044
BIT61Bit61p0.042
SAM3Sam3p0.042
TPN1Tpn1p0.041
ALT1Alt1p0.041
MET6Met6p0.041
YER163Chypothetical protein0.040
SRD1Srd1p0.040
ADO1Ado1p0.039
GDH1Gdh1p0.038
ADE1Ade1p0.038
STF1Stf1p0.038
FAS2Fas2p0.036
YLR264C-Ahypothetical protein0.036
ARP10Arp10p0.035
ODC1Odc1p0.035
YGR205Whypothetical protein0.035
ADP1Adp1p0.035
YLR281Chypothetical protein0.035
YCT1Yct1p0.034
YOL038C-Ahypothetical protein0.034
YAT2Yat2p0.034
BSC1Bsc1p0.033
RPE1Rpe1p0.033
ARO9Aro9p0.033
MER1Mer1p0.032
ICL2Icl2p0.032
MET16Met16p0.031
MMF1Mmf1p0.031
YLR042Chypothetical protein0.030
ADH6Adh6p0.030
ALP1Alp1p0.030
YLR162Whypothetical protein0.030
ARR2Arr2p0.030
YPR157Whypothetical protein0.029
YJR085Chypothetical protein0.029
DUG1Dug1p0.029
YOR302Whypothetical protein0.028
CUP1-1Cup1-1p0.028
CYB2Cyb2p0.028
MET14Met14p0.028
HPF1Hpf1p0.028
YGR016Whypothetical protein0.027
YAR068Whypothetical protein0.027
ZPS1Zps1p0.027
PCL9Pcl9p0.027
ATP6Atp6p0.027
MET8Met8p0.027
YIR035Chypothetical protein0.027
SRX1Srx1p0.026
SMF1Smf1p0.026
YIR042Chypothetical protein0.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.801
AARSalanyl-tRNA synthetase0.691
GARSglycyl-tRNA synthetase0.659
MARSmethionyl-tRNA synthetase0.616
PSAT1phosphoserine aminotransferase 10.538
YARStyrosyl-tRNA synthetase0.431
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.309
ASNSasparagine synthetase (glutamine-hydrolyzing)0.296
TRIB3tribbles homolog 3 (Drosophila)0.123
CARScysteinyl-tRNA synthetase0.121
SHMT2serine hydroxymethyltransferase 2 (mitochondrial)0.121
ALDOBaldolase B, fructose-bisphosphate0.087
PHGDHphosphoglycerate dehydrogenase0.083
TUBGCP4tubulin, gamma complex associated protein 40.068
IARSisoleucyl-tRNA synthetase0.054
LONP1lon peptidase 1, mitochondrial0.045
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.041
MTHFD2methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase0.039
XPOTexportin, tRNA (nuclear export receptor for tRNAs)0.036
GPT2glutamic pyruvate transaminase (alanine aminotransferase) 20.020
SARSseryl-tRNA synthetase0.018
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma0.014
ZNF277zinc finger protein 2770.014
SLC7A5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.012
TIMM44translocase of inner mitochondrial membrane 44 homolog (yeast)0.012
TARSthreonyl-tRNA synthetase0.012
CHAC1ChaC, cation transport regulator homolog 1 (E. coli)0.011
SLC3A2solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 20.011
SLC1A5solute carrier family 1 (neutral amino acid transporter), member 50.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gclcglutamate-cysteine ligase, catalytic subunit0.995
Gclmglutamate-cysteine ligase, modifier subunit0.991
Atad3aATPase family, AAA domain containing 3A0.264
BC048355cDNA sequence BC0483550.124
Gsrglutathione reductase0.098
Gnrh1gonadotropin releasing hormone 10.089
Shmt1serine hydroxymethyltransferase 1 (soluble)0.082
Dazap1DAZ associated protein 10.060
Fpgsfolylpolyglutamyl synthetase0.059
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.053
Umpsuridine monophosphate synthetase0.046
Slc19a1solute carrier family 19 (sodium/hydrogen exchanger), member 10.039
Acy1aminoacylase 10.037
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.031
Dok1docking protein 10.029
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.028
Lactb2lactamase, beta 20.026
Ifrd2interferon-related developmental regulator 20.025
C1qbpcomplement component 1, q subcomponent binding protein0.025
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.024
Phlda2pleckstrin homology-like domain, family A, member 20.022
F13bcoagulation factor XIII, beta subunit0.020
Smyd5SET and MYND domain containing 50.019
Tbrg4transforming growth factor beta regulated gene 40.019
Pbld2phenazine biosynthesis-like protein domain containing 20.018
Aldobaldolase B, fructose-bisphosphate0.018
Usp10ubiquitin specific peptidase 100.018
Hspa9heat shock protein 90.017
Rrp1bribosomal RNA processing 1 homolog B (S. cerevisiae)0.017
Mifmacrophage migration inhibitory factor0.017
Gdf15growth differentiation factor 150.016
Rrp9RRP9, small subunit (SSU) processome component, homolog (yeast)0.016
Sfxn1sideroflexin 10.016
Agxtalanine-glyoxylate aminotransferase0.016
Tmem183atransmembrane protein 183A0.016
Clcnkachloride channel Ka0.016
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.016
Eif4a1eukaryotic translation initiation factor 4A10.015
Sars2seryl-aminoacyl-tRNA synthetase 20.015
Tspan12tetraspanin 120.015
Sardhsarcosine dehydrogenase0.015
Aldh18a1aldehyde dehydrogenase 18 family, member A10.015
Eif4g1eukaryotic translation initiation factor 4, gamma 10.014
Prodh2proline dehydrogenase (oxidase) 20.014
Tpmtthiopurine methyltransferase0.014
Lap3leucine aminopeptidase 30.014
Prodhproline dehydrogenase0.014
Hgdhomogentisate 1, 2-dioxygenase0.014
Vegfavascular endothelial growth factor A0.013
Mosc1MOCO sulphurase C-terminal domain containing 10.013
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase0.013
Plin5perilipin 50.013
Aspgasparaginase homolog (S. cerevisiae)0.013
Pzppregnancy zone protein0.013
Gykglycerol kinase0.013
Ftcdformiminotransferase cyclodeaminase0.013
Slc25a13solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 130.012
Mpzl2myelin protein zero-like 20.012
Agmatagmatine ureohydrolase (agmatinase)0.012
Mybl2myeloblastosis oncogene-like 20.012
Hpnhepsin0.012
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.012
Gjb1gap junction protein, beta 10.012
Slc26a1solute carrier family 26 (sulfate transporter), member 10.012
Cwf19l1CWF19-like 1, cell cycle control (S. pombe)0.011
Ggnbp1gametogenetin binding protein 10.011
Stc2stanniocalcin 20.011
Zfp335zinc finger protein 3350.011
Psmg3proteasome (prosome, macropain) assembly chaperone 30.011
Gnmtglycine N-methyltransferase0.011
Sod2superoxide dismutase 2, mitochondrial0.011
NadkNAD kinase0.010
Pkp3plakophilin 30.010
Dmgdhdimethylglycine dehydrogenase precursor0.010
Slc22a6solute carrier family 22 (organic anion transporter), member 60.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Mat1amethionine adenosyltransferase I, alpha0.168
Dpysdihydropyrimidinase0.114
Upb1ureidopropionase, beta0.065
Car5acarbonic anhydrase 5a, mitochondrial0.062
Asgr1asialoglycoprotein receptor 10.041
Pahphenylalanine hydroxylase0.040
Ass1argininosuccinate synthetase 10.039
Mromaestro0.039
Olr59olfactory receptor 590.038
Gtpbp4GTP binding protein 40.031
Ube2zubiquitin-conjugating enzyme E2Z0.030
Fabp1fatty acid binding protein 1, liver0.029
Nolc1nucleolar and coiled-body phosphoprotein 10.029
Gys2glycogen synthase 20.028
Unguracil-DNA glycosylase0.028
Afmafamin0.027
Sdsserine dehydratase0.026
Ahcyadenosylhomocysteinase0.025
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.024
Rcan1regulator of calcineurin 10.024
Tbl3transducin (beta)-like 30.023
Azgp1alpha-2-glycoprotein 1, zinc-binding0.023
Fbp1fructose-1,6-bisphosphatase 10.022
Prodh2proline dehydrogenase (oxidase) 20.022
Faahfatty acid amide hydrolase0.022
Apoc4apolipoprotein C-IV0.021
Sardhsarcosine dehydrogenase0.021
Tfectranscription factor EC0.021
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.021
Lipclipase, hepatic0.020
Gulogulonolactone (L-) oxidase0.020
RGD1305347similar to RIKEN cDNA 2610528J110.020
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.020
Dhtkd1dehydrogenase E1 and transketolase domain containing 10.019
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.019
Dmgdhdimethylglycine dehydrogenase0.019
Hmbshydroxymethylbilane synthase0.018
Xpnpep2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound0.018
Aadacarylacetamide deacetylase (esterase)0.018
Keg1kidney expressed gene 10.018
Nr1h4nuclear receptor subfamily 1, group H, member 40.018
Kynukynureninase (L-kynurenine hydrolase)0.017
Ubqln1ubiquilin 10.017
Prss2protease, serine, 20.017
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.016
Apomapolipoprotein M0.016
Grhprglyoxylate reductase/hydroxypyruvate reductase0.016
Apobapolipoprotein B0.016
Slc31a1solute carrier family 31 (copper transporters), member 10.016
Hpd4-hydroxyphenylpyruvate dioxygenase0.016
Hnf1aHNF1 homeobox A0.015
Bola3bolA homolog 3 (E. coli)0.015
Bhmtbetaine-homocysteine methyltransferase0.015
Hpnhepsin0.015
Aadataminoadipate aminotransferase0.015
Adhfe1alcohol dehydrogenase, iron containing, 10.015
Mdm2Mdm2 p53 binding protein homolog (mouse)0.015
Procprotein C0.014
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.014
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.014
Tp53tumor protein p530.014
Afpalpha-fetoprotein0.014
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.014
Atad3aATPase family, AAA domain containing 3A0.014
Cela1chymotrypsin-like elastase family, member 10.014
Snrpasmall nuclear ribonucleoprotein polypeptide A0.014
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.013
Gjb1gap junction protein, beta 10.013
RGD620382Nucleoside 2-deoxyribosyltransferase domain containing protein RGD6203820.013
Casp6caspase 60.013
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.013
Bckdhbbranched chain keto acid dehydrogenase E1, beta polypeptide0.012
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.012
Pdcd6ipprogrammed cell death 6 interacting protein0.012
Vcpvalosin-containing protein0.012
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.012
Ces1ccarboxylesterase 1C0.012
Thop1thimet oligopeptidase 10.012
Hmox1heme oxygenase (decycling) 10.012
Pus1pseudouridylate synthase 10.012
Amhanti-Mullerian hormone0.011
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.011
Dcxrdicarbonyl L-xylulose reductase0.011
Gckrglucokinase (hexokinase 4) regulator0.011
Khkketohexokinase0.011
Slco1b3solute carrier organic anion transporter family, member 1b30.011
Dhfrdihydrofolate reductase0.011
Halhistidine ammonia lyase0.011
Adh1alcohol dehydrogenase 1 (class I)0.011
Gclcglutamate-cysteine ligase, catalytic subunit0.010
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.010
Dpyddihydropyrimidine dehydrogenase0.010
RGD1564865similar to 20-alpha-hydroxysteroid dehydrogenase0.010
Mocs1molybdenum cofactor synthesis 10.010
Haao3-hydroxyanthranilate 3,4-dioxygenase0.010