The network for 'regulation of exit from mitosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of exit from mitosis

Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.

NameDescriptionProbabilityFunc Analog Organism
CDC14Cdc14p0.926
GIC1Gic1p0.893
BUB2Bub2p0.752
KEL1Kel1p0.719
BFA1Bfa1p0.718
GIC2Gic2p0.707
SSK1Ssk1p0.511
ZDS2Zds2p0.351
NUD1Nud1p0.350
CDC12Cdc12p0.322
LTE1Lte1p0.322
PBS2Pbs2p0.312
CDC5Cdc5p0.307
CDC15Cdc15p0.229
KIN2Kin2p0.220
BCK2Bck2p0.219
NBP2Nbp2p0.211
CLA4Cla4p0.204
ZDS1Zds1p0.188
STE5Ste5p0.173
NOG1Nog1p0.169
SKP2Skp2p0.167
MPS1Mps1p0.166
FAR1Far1p0.139
TEM1Tem1p0.136
SWE1Swe1p0.136
CDC24Cdc24p0.135
SSK2Ssk2p0.134
CDC37Cdc37p0.129
CDC20Cdc20p0.128
GLC7Glc7p0.122
CDC28Cdc28p0.107
RPN2Rpn2p0.107
DMA1Dma1p0.100
YMR124Whypothetical protein0.097
STE23Ste23p0.091
TOF2Tof2p0.091
BMH1Bmh1p0.091
TPD3Tpd3p0.083
KIN3Kin3p0.082
PRS2Prs2p0.078
AXL2Axl2p0.078
BEM3Bem3p0.078
DBF2Dbf2p0.075
DYN1Dyn1p0.074
FAR11Far11p0.067
DMA2Dma2p0.067
CDC53Cdc53p0.067
RRP14Rrp14p0.064
FIN1Fin1p0.064
KIP2Kip2p0.063
RPT4Rpt4p0.062
NDD1Ndd1p0.059
DYN3Dyn3p0.048
SPC97Spc97p0.045
IML1Iml1p0.044
RPN3Rpn3p0.043
CDC55Cdc55p0.043
ORC6Orc6p0.041
YLR419Whypothetical protein0.041
IQG1Iqg1p0.040
PCL9Pcl9p0.040
YLR162Whypothetical protein0.039
SUT1Sut1p0.038
SRD1Srd1p0.037
GYL1Gyl1p0.037
CTF13Ctf13p0.035
PDC5Pdc5p0.035
YLR264C-Ahypothetical protein0.034
LEU2Leu2p0.034
YOL038C-Ahypothetical protein0.033
STE7Ste7p0.033
SSK22Ssk22p0.033
PTI1Pti1p0.032
SQS1Sqs1p0.032
PPH21Pph21p0.032
BUD8Bud8p0.032
STU1Stu1p0.032
BUD6Bud6p0.031
HAL5Hal5p0.031
PDC6Pdc6p0.031
FPR3Fpr3p0.031
YNL058Chypothetical protein0.030
HKR1Hkr1p0.030
ARP10Arp10p0.030
YIL151Chypothetical protein0.029
URA3Ura3p0.029
ADH2Adh2p0.029
CDC4Cdc4p0.029
MDN1Mdn1p0.029
BUD9Bud9p0.028
MER1Mer1p0.028
SPC29Spc29p0.028
MCM10Mcm10p0.028
RHO1Rho1p0.027
KIC1Kic1p0.027
PTR2Ptr2p0.027
NAP1Nap1p0.027
CUP1-1Cup1-1p0.027
RRT5Rrt5p0.027
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.019
dladeltaA0.018
tbx2bT-box 2b0.015
cxcr4bchemokine (C-X-C motif), receptor 4b0.015
spry4sprouty (Drosophila) homolog 40.014
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.014
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.011
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.011
meis1myeloid ecotropic viral integration 10.010
ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dapdacapo0.409
CycACyclin A0.323
stgstring0.192
MybMyb oncogene-like0.164
hpohippo0.074
Akt1CG4006 gene product from transcript CG4006-RA0.051
ttktramtrack0.046
bazbazooka0.043
cmetCENP-meta0.034
poloCG12306 gene product from transcript CG12306-RA0.024
Top1Topoisomerase 10.023
CycECyclin E0.022
SAKSak kinase0.021
RhebCG1081 gene product from transcript CG1081-RA0.018
drprdraper0.017
kuzkuzbanian0.017
dmdiminutive0.017
RalaRas-related protein0.016
aspabnormal spindle0.015
aslasterless0.014
pimpimples0.014
Cdc27CG8610 gene product from transcript CG8610-RA0.014
Cks30ACyclin-dependent kinase subunit 30A0.013
kibrakibra ortholog0.012
Su(H)Suppressor of Hairless0.012
chbchromosome bows0.012
Nopp140CG7421 gene product from transcript CG7421-RB0.012
CycBCyclin B0.011
Nop60BNucleolar protein at 60B0.011
Nuf2CG8902 gene product from transcript CG8902-RA0.010
Syx13Syntaxin 130.010
l(2)gllethal (2) giant larvae0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDK2cyclin-dependent kinase 20.967
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.578
CDC20cell division cycle 20 homolog (S. cerevisiae)0.221
SKP2S-phase kinase-associated protein 2 (p45)0.215
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.117
CCT8chaperonin containing TCP1, subunit 8 (theta)0.113
CCNB1cyclin B10.104
CKS1BCDC28 protein kinase regulatory subunit 1B0.069
CCNE1cyclin E10.059
CDC6cell division cycle 6 homolog (S. cerevisiae)0.053
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.049
CCNB2cyclin B20.042
CCNA2cyclin A20.035
CCND1cyclin D10.033
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.030
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.025
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.024
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.023
CDKN3cyclin-dependent kinase inhibitor 30.022
CDC45cell division cycle 45 homolog (S. cerevisiae)0.022
CCND3cyclin D30.021
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.018
AURKBaurora kinase B0.018
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.017
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.016
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.015
ORC1origin recognition complex, subunit 10.014
PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.014
CCNE2cyclin E20.014
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.014
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.013
CKS2CDC28 protein kinase regulatory subunit 20.012
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.012
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.011
TRIP13thyroid hormone receptor interactor 130.010
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.994
Neurod1neurogenic differentiation 10.986
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.982
Ascl1achaete-scute complex homolog 1 (Drosophila)0.967
Shhsonic hedgehog0.959
Cdk1cyclin-dependent kinase 10.954
Ccnb1cyclin B10.922
Ube2cubiquitin-conjugating enzyme E2C0.920
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.920
Rac1RAS-related C3 botulinum substrate 10.917
Kif20akinesin family member 20A0.905
Cdk2cyclin-dependent kinase 20.903
Ccnb2cyclin B20.899
Neurog2neurogenin 20.803
Rpgrip1lRpgrip1-like0.801
Ccne1cyclin E10.754
Lrrk2leucine-rich repeat kinase 20.747
Kiss1KiSS-1 metastasis-suppressor0.730
Otx2orthodenticle homolog 2 (Drosophila)0.714
Gata4GATA binding protein 40.708
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.697
Pax6paired box gene 60.687
Cdca8cell division cycle associated 80.596
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.572
MecomMDS1 and EVI1 complex locus0.572
Tcf3transcription factor 30.568
Prc1protein regulator of cytokinesis 10.568
Gata1GATA binding protein 10.555
Neurog3neurogenin 30.529
Neurod4neurogenic differentiation 40.525
Isl1ISL1 transcription factor, LIM/homeodomain0.452
Mki67antigen identified by monoclonal antibody Ki 670.448
Lepleptin0.441
Lhx5LIM homeobox protein 50.437
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.404
Cirh1acirrhosis, autosomal recessive 1A (human)0.399
Kif22kinesin family member 220.375
Racgap1Rac GTPase-activating protein 10.350
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.344
Onecut1one cut domain, family member 10.343
Gscgoosecoid homeobox0.338
Mxd3Max dimerization protein 30.338
Rrm2ribonucleotide reductase M20.337
Plk1polo-like kinase 1 (Drosophila)0.336
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.303
Sox1SRY-box containing gene 10.298
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.298
Gnrh1gonadotropin releasing hormone 10.273
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.260
Hoxd13homeobox D130.248
Tcf19transcription factor 190.242
Ccna2cyclin A20.240
Alx3aristaless-like homeobox 30.234
Nr5a1nuclear receptor subfamily 5, group A, member 10.221
Hba-xhemoglobin X, alpha-like embryonic chain in Hba complex0.219
H2afxH2A histone family, member X0.215
En1engrailed 10.213
BadBCL2-associated agonist of cell death0.209
Msx1homeobox, msh-like 10.204
Gpr50G-protein-coupled receptor 500.201
Cks2CDC28 protein kinase regulatory subunit 20.200
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.199
Sim2single-minded homolog 2 (Drosophila)0.192
Lhcgrluteinizing hormone/choriogonadotropin receptor0.186
Ptf1apancreas specific transcription factor, 1a0.183
Trp53transformation related protein 530.180
Ccnfcyclin F0.175
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.173
Lhx9LIM homeobox protein 90.172
Lhx3LIM homeobox protein 30.169
Hoxc5homeobox C50.162
Ckap2cytoskeleton associated protein 20.153
Gtse1G two S phase expressed protein 10.152
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.148
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.148
Tcfap2atranscription factor AP-2, alpha0.147
Tcf15transcription factor 150.145
Aurkaaurora kinase A0.144
H1histocompatibility 10.144
Cenpecentromere protein E0.141
Lmo2LIM domain only 20.139
Fam64afamily with sequence similarity 64, member A0.138
Insm1insulinoma-associated 10.138
Pik3cbphosphatidylinositol 3-kinase, catalytic, beta polypeptide0.137
Lmo1LIM domain only 10.134
Spag5sperm associated antigen 50.134
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.133
Prph2peripherin 20.131
Notch2Notch gene homolog 2 (Drosophila)0.129
Foxd2forkhead box D20.127
Sgol1shugoshin-like 1 (S. pombe)0.122
Melkmaternal embryonic leucine zipper kinase0.120
Pou4f2POU domain, class 4, transcription factor 20.119
Dab1disabled homolog 1 (Drosophila)0.117
Pitx1paired-like homeodomain transcription factor 10.117
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.112
Top2atopoisomerase (DNA) II alpha0.109
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.108
Gja1gap junction protein, alpha 10.108
Tlx3T-cell leukemia, homeobox 30.107
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Taok1TAO kinase 10.158
Mcm5minichromosome maintenance complex component 50.059
Top2atopoisomerase (DNA) II alpha0.041
Myh9myosin, heavy chain 9, non-muscle0.030
Msnmoesin0.029
Dctn4dynactin 40.028
Smad7SMAD family member 70.026
Fgfr1Fibroblast growth factor receptor 10.024
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.022
Il3interleukin 30.021
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.020
Tpothyroid peroxidase0.019
Prkcbprotein kinase C, beta0.018
Nxph4neurexophilin 40.018
Arnt2aryl hydrocarbon receptor nuclear translocator 20.018
Fxyd5FXYD domain-containing ion transport regulator 50.017
Golph3golgi phosphoprotein 3 (coat-protein)0.017
Fkbp1bFK506 binding protein 1b0.016
Col9a1collagen, type IX, alpha 10.016
Epha8Eph receptor A80.016
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.015
Nek9NIMA (never in mitosis gene a)- related kinase 90.015
Opcmlopioid binding protein/cell adhesion molecule-like0.015
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.014
Hmga2high mobility group AT-hook 20.014
Gabra2gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 20.014
RragBRas-related GTP binding B0.014
Hes3hairy and enhancer of split 3 (Drosophila)0.014
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.013
Zfp37zinc finger protein 370.013
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.013
Tulp1tubby like protein 10.013
Mmp16matrix metallopeptidase 160.013
Prlhprolactin releasing hormone0.013
Slc26a1solute carrier family 26 (sulfate transporter), member 10.013
Foxd4forkhead box D40.012
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.012
Myh10myosin, heavy chain 10, non-muscle0.012
Prol1proline rich, lacrimal 10.012
Slc30a1solute carrier family 30 (zinc transporter), member 10.012
Pcsk1proprotein convertase subtilisin/kexin type 10.012
Rgs19regulator of G-protein signaling 190.012
Has2hyaluronan synthase 20.012
Alx1ALX homeobox 10.012
Grem1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)0.012
Lig3ligase III, DNA, ATP-dependent0.011
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.011
Il2interleukin 20.011
Nmnat2nicotinamide nucleotide adenylyltransferase 20.011
Mapk1mitogen activated protein kinase 10.011
Myh13myosin, heavy chain 13, skeletal muscle0.011
Scn3asodium channel, voltage-gated, type III, alpha0.011
St8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.011
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.011
Nr5a1nuclear receptor subfamily 5, group A, member 10.011
Tshbthyroid stimulating hormone, beta0.010
Fgf16fibroblast growth factor 160.010
Cntfrciliary neurotrophic factor receptor0.010
Ascl1achaete-scute complex homolog 1 (Drosophila)0.010
Clec11aC-type lectin domain family 11, member a0.010
Soat1sterol O-acyltransferase 10.010
Nppcnatriuretic peptide precursor C0.010
Csnk1g3casein kinase 1, gamma 30.010