The network for 'aflatoxin metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

aflatoxin metabolic process

The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.143
upp2uridine phosphorylase 20.113
cyp51cytochrome P450, family 510.064
nr5a5nuclear receptor subfamily 5, group A, member 50.054
procprotein C (inactivator of coagulation factors Va and VIIIa)0.052
sult1st3sulfotransferase family 1, cytosolic sulfotransferase 30.050
ahsgalpha-2-HS-glycoprotein0.049
lipclipase, hepatic0.042
abp1amiloride binding protein 1 (amine oxidase (copper-containing))0.037
slc34a2asolute carrier family 34 (sodium phosphate), member 2a0.035
mep1a.1meprin A, alpha.10.033
cyp2aa1cytochrome P450, family 2, subfamily AA, polypeptide 10.030
chia.2chitinase, acidic.20.030
cyp4t8cytochrome P450, family 4, subfamily T, polypeptide 80.029
shbgsex hormone binding globulin0.028
igfbp1binsulin-like growth factor binding protein 1b0.027
LOC569770cytochrome c oxidase subunit 8B, mitochondrial-like0.024
srd5a2asteroid-5-alpha-reductase, alpha polypeptide 2a0.023
map9microtubule-associated protein 90.023
angptl3angiopoietin-like 30.023
spata18spermatogenesis associated 180.022
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.022
shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.022
ahr1aaryl hydrocarbon receptor 1a0.021
irgq1immunity-related GTPase family, q10.021
agmoalkylglycerol monooxygenase0.020
zgc:113516zgc:1135160.020
zgc:64076zgc:640760.019
zgc:56326zgc:563260.018
cyp2k18cytochrome P450, family 2, subfamily K, polypeptide 180.017
pklrpyruvate kinase, liver and RBC0.017
zgc:92406zgc:924060.017
cpne3copine III0.017
fabp10afatty acid binding protein 10a, liver basic0.017
hbl3hexose-binding lectin 30.017
starsteroidogenic acute regulatory protein0.017
ca9carbonic anhydrase IX0.016
hsd17b3hydroxysteroid (17-beta) dehydrogenase 30.016
slc8a4bsolute carrier family 8 (sodium/calcium exchanger), member 4b0.016
acad11acyl-Coenzyme A dehydrogenase family, member 110.016
zgc:112432zgc:1124320.015
sat2spermidine/spermine N1-acetyltransferase family member 20.015
bcdo2lbeta-carotene 15, 15-dioxygenase 2, like0.014
cx32.3connexin 32.30.014
zgc:66484zgc:664840.014
mospd2motile sperm domain containing 20.014
oclnaoccludin a0.014
zgc:56622zgc:566220.014
hprt1hypoxanthine phosphoribosyltransferase 10.014
hpxhemopexin0.014
zgc:198195zgc:1981950.013
zgc:153921zgc:1539210.013
hnf4ahepatocyte nuclear factor 4, alpha0.013
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.013
tbxas1thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)0.013
vtg4vitellogenin 40.013
cyp2p6cytochrome P450, family 2, subfamily P, polypeptide 60.012
agtangiotensinogen0.012
aqp12aquaporin 120.012
dio1deiodinase, iodothyronine, type I0.012
zgc:63774zgc:637740.012
ldhbblactate dehydrogenase Bb0.012
hprt1lhypoxanthine phosphoribosyltransferase 1, like0.012
si:ch211-93f2.1si:ch211-93f2.10.011
im:7138629im:71386290.011
gcshbglycine cleavage system protein H (aminomethyl carrier), b0.011
uoxurate oxidase0.011
irf9interferon regulatory factor 90.011
LOC559127similar to AWKS93720.011
LOC100005232Gig2-like protein DreD0.011
serpinb1l3serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 30.011
acox3acyl-Coenzyme A oxidase 3, pristanoyl0.011
grk5G protein-coupled receptor kinase 50.011
ela2elastase 20.011
cpa1carboxypeptidase A1 (pancreatic)0.011
lonp2lon peptidase 2, peroxisomal0.010
sult3st1sulfotransferase family 3, cytosolic sulfotransferase 10.010
bbs7Bardet-Biedl syndrome 70.010
slc25a27solute carrier family 25, member 270.010
gstalglutathione S-transferase, alpha-like0.010
adh8aalcohol dehydrogenase 8a0.010
cldncclaudin c0.010
cldn11bclaudin 11b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gstm1glutathione S-transferase, mu 10.194
Gstt1glutathione S-transferase, theta 10.099
Cbr1carbonyl reductase 10.070
Selenbp1selenium binding protein 10.046
Prdx6peroxiredoxin 60.043
Gsto1glutathione S-transferase omega 10.034
Ces1dcarboxylesterase 1D0.031
Pgls6-phosphogluconolactonase0.027
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.027
Cmblcarboxymethylenebutenolidase-like (Pseudomonas)0.022
Cyb5cytochrome b-50.020
Tmem205transmembrane protein 2050.017
Gstk1glutathione S-transferase kappa 10.015
Aox1aldehyde oxidase 10.013
BC004004cDNA sequence BC0040040.012
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.011
Eci1enoyl-Coenzyme A delta isomerase 10.011
Chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.011
Adh1alcohol dehydrogenase 1 (class I)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism