The network for 'metaphase plate congression' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metaphase plate congression

The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
klp-19Protein KLP-190.632
mcm-7Protein MCM-70.290
prp-8Protein PRP-80.144
aspm-1Protein ASPM-10.128
cul-1Protein CUL-10.125
rod-1Protein ROD-10.111
bub-1Protein BUB-10.092
top-2Protein TOP-20.076
hcp-2Protein HCP-20.066
F33H2.5Protein F33H2.50.064
spd-1Protein SPD-10.052
hcp-1Protein HCP-10.052
scc-1Protein SCC-10.051
CELE_Y53F4B.9Protein Y53F4B.90.049
perm-1Protein PERM-10.048
lin-5Protein LIN-50.047
mel-28Protein MEL-280.043
cin-4Protein CIN-40.041
npp-11Protein NPP-110.041
nasp-2Protein NASP-20.040
npp-21Protein NPP-210.038
F54C4.4Protein F54C4.40.038
T20F5.7Protein T20F5.70.037
T19H12.2Protein T19H12.20.037
ZK1127.5Protein ZK1127.50.031
rsd-2Protein RSD-20.030
npp-3Protein NPP-30.029
fzy-1Protein FZY-10.028
lin-13Protein LIN-130.027
R05D3.2Protein R05D3.20.027
cec-4Protein CEC-40.026
let-858Protein LET-8580.026
rnr-1Protein RNR-10.026
knl-1Protein KNL-10.025
tiar-1Protein TIAR-10.024
zyg-9Protein ZYG-90.023
dsh-2Protein DSH-20.022
pcn-1Protein PCN-10.020
fbxa-215Protein FBXA-2150.019
sgo-1Protein SGO-10.019
fib-1Protein FIB-10.019
rsp-1Protein RSP-10.019
mcm-2Protein MCM-20.019
ubxn-1Protein UBXN-10.018
clec-88Protein CLEC-880.018
gpd-4Protein GPD-40.017
math-33Protein MATH-330.017
CELE_C39E9.12Protein C39E9.120.017
bmk-1Protein BMK-10.017
F54E12.2Protein F54E12.20.016
T07C4.10Protein T07C4.100.015
xpo-2Protein XPO-20.015
zen-4Protein ZEN-40.015
cdl-1Protein CDL-10.015
hcp-4Protein HCP-40.015
mep-1Protein MEP-10.014
hil-4Protein HIL-40.014
T08A11.2Protein T08A11.20.014
hpo-9Protein HPO-90.014
cids-2Protein CIDS-20.013
inft-2Protein INFT-20.013
hsr-9Protein HSR-90.012
T28D9.4Protein T28D9.40.012
cyk-4Protein CYK-40.012
smc-6Protein SMC-60.012
sdz-27Protein SDZ-270.012
sun-1Protein SUN-10.012
immt-2Protein IMMT-20.012
CELE_R06A4.2Protein R06A4.20.012
isw-1Protein ISW-10.012
Y4C6B.1Protein Y4C6B.10.012
npp-10Protein NPP-100.012
eif-3.BProtein EIF-3.B0.012
cgh-1Protein CGH-10.011
mcm-4Protein MCM-40.011
klp-7Protein KLP-70.010
C44B9.3Protein C44B9.30.010
F11E6.7Protein F11E6.70.010
bath-42Protein BATH-420.010
mcm-3Protein MCM-30.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
aurkbaurora kinase B0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Nuf2CG8902 gene product from transcript CG8902-RA0.995
Mis12CG18156 gene product from transcript CG18156-RA0.964
Ndc80CG9938 gene product from transcript CG9938-RA0.962
cidcentromere identifier0.945
Cenp-CCG31258 gene product from transcript CG31258-RA0.885
ncdnon-claret disjunctional0.803
Spc25CG7242 gene product from transcript CG7242-RA0.786
marsCG17064 gene product from transcript CG17064-RB0.700
IncenpInner centromere protein0.563
Kmn1kinetochore Mis12-Ndc80 network component 10.463
Nnf1aCG13434 gene product from transcript CG13434-RA0.452
Nnf1bCG31658 gene product from transcript CG31658-RA0.438
SMC2CG10212 gene product from transcript CG10212-RA0.389
larpLa related protein0.327
IswiImitation SWI0.266
pitaCG3941 gene product from transcript CG3941-RA0.233
Klp61FKinesin-like protein at 61F0.172
CG13350CG13350 gene product from transcript CG13350-RA0.126
msd1mitotic spindle density 10.113
Poc1Proteome of centrioles 10.104
tacctransforming acidic coiled-coil protein0.080
gammaTub37Cgamma-Tubulin at 37C0.079
Nup153Nucleoporin 1530.079
dpadisc proliferation abnormal0.063
CG11120CG11120 gene product from transcript CG11120-RA0.062
BthDBthD selenoprotein0.058
Cap-GCG34438 gene product from transcript CG34438-RF0.055
Cks30ACyclin-dependent kinase subunit 30A0.053
AGO2Argonaute 20.050
Klp67AKinesin-like protein at 67A0.045
mei-38meiotic 380.044
hydhyperplastic discs0.039
lkb1CG9374 gene product from transcript CG9374-RJ0.034
pngpan gu0.034
Klp10ACG1453 gene product from transcript CG1453-RA0.034
CG5146CG5146 gene product from transcript CG5146-RA0.029
cdc23CG2508 gene product from transcript CG2508-RA0.027
ialIplI-aurora-like kinase0.026
Orc5Origin recognition complex subunit 50.026
Rrp4CG3931 gene product from transcript CG3931-RA0.025
xl6CG10203 gene product from transcript CG10203-RA0.025
dupdouble parked0.024
TsCG3181 gene product from transcript CG3181-RA0.024
CycB3Cyclin B30.023
DNApol-alpha50DNA polymerase alpha 50kD0.023
CG4699CG4699 gene product from transcript CG4699-RJ0.021
l(1)G0007lethal (1) G00070.021
CG12018CG12018 gene product from transcript CG12018-RA0.019
KP78bCG17216 gene product from transcript CG17216-RB0.018
BubR1Bub1-related kinase0.018
CG11329CG11329 gene product from transcript CG11329-RA0.018
DlicDynein light intermediate chain0.017
Cdc37CG12019 gene product from transcript CG12019-RA0.016
boraaurora borealis0.016
Pole2CG10489 gene product from transcript CG10489-RA0.015
tlkTousled-like kinase0.014
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.013
CG7971CG7971 gene product from transcript CG7971-RC0.013
dgt4dim gamma-tubulin 40.013
CG8173CG8173 gene product from transcript CG8173-RA0.012
DNApol-alpha180DNA polymerase alpha 180kD0.012
CstF-64Cleavage stimulation factor 64 kilodalton subunit0.012
Cdc27CG8610 gene product from transcript CG8610-RA0.012
Myo61FMyosin 61F0.011
InvadolysinCG3953 gene product from transcript CG3953-RA0.011
Pp1alpha-96AProtein phosphatase 1alpha at 96A0.011
Cep135CG17081 gene product from transcript CG17081-RB0.011
Nf-YCNuclear factor Y-box C0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.799
CCNB1cyclin B10.518
CDC20cell division cycle 20 homolog (S. cerevisiae)0.445
NUP107nucleoporin 107kDa0.344
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.296
INCENPinner centromere protein antigens 135/155kDa0.278
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.253
RACGAP1Rac GTPase activating protein 10.207
CENPEcentromere protein E, 312kDa0.201
RB1retinoblastoma 10.198
AURKBaurora kinase B0.192
CCNA2cyclin A20.163
CDC27cell division cycle 27 homolog (S. cerevisiae)0.147
PARP1poly (ADP-ribose) polymerase 10.136
TOP2Atopoisomerase (DNA) II alpha 170kDa0.131
HMMRhyaluronan-mediated motility receptor (RHAMM)0.115
AHCTF1AT hook containing transcription factor 10.114
NUP133nucleoporin 133kDa0.111
CENPFcentromere protein F, 350/400kDa (mitosin)0.107
CDK2cyclin-dependent kinase 20.104
CKAP5cytoskeleton associated protein 50.101
KIF20Akinesin family member 20A0.094
BRIP1BRCA1 interacting protein C-terminal helicase 10.087
CDK1cyclin-dependent kinase 10.082
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.074
SUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae)0.069
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.064
CBX5chromobox homolog 50.063
ZWINTZW10 interactor0.063
PRC1protein regulator of cytokinesis 10.062
KIF23kinesin family member 230.062
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.062
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.060
NEK2NIMA (never in mitosis gene a)-related kinase 20.060
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.059
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.056
SGOL2shugoshin-like 2 (S. pombe)0.049
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.048
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.044
BLMBloom syndrome, RecQ helicase-like0.043
NOLC1nucleolar and coiled-body phosphoprotein 10.043
LBRlamin B receptor0.040
BIRC5baculoviral IAP repeat containing 50.039
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.039
MIS18BP1MIS18 binding protein 10.037
C13orf34chromosome 13 open reading frame 340.037
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.036
SGOL1shugoshin-like 1 (S. pombe)0.036
KIF1Bkinesin family member 1B0.035
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.035
UBE4Bubiquitination factor E4B (UFD2 homolog, yeast)0.034
CCNE1cyclin E10.033
FBXO5F-box protein 50.033
OPA1optic atrophy 1 (autosomal dominant)0.033
CCNE2cyclin E20.032
XPO1exportin 1 (CRM1 homolog, yeast)0.032
GPSM2G-protein signaling modulator 20.031
BRCA1breast cancer 1, early onset0.031
NUP43nucleoporin 43kDa0.031
DLGAP5discs, large (Drosophila) homolog-associated protein 50.030
CEP55centrosomal protein 55kDa0.029
RBL1retinoblastoma-like 1 (p107)0.029
CCNB2cyclin B20.029
KIF11kinesin family member 110.028
PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 80.027
PHAXphosphorylated adaptor for RNA export0.025
CASC5cancer susceptibility candidate 50.025
NCAPGnon-SMC condensin I complex, subunit G0.025
YTHDC2YTH domain containing 20.024
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.023
MSH6mutS homolog 6 (E. coli)0.023
ECT2epithelial cell transforming sequence 2 oncogene0.022
NCAPHnon-SMC condensin I complex, subunit H0.022
BRCA2breast cancer 2, early onset0.021
PDS5APDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.020
E2F5E2F transcription factor 5, p130-binding0.020
KIF14kinesin family member 140.020
C4orf43chromosome 4 open reading frame 430.020
HDAC2histone deacetylase 20.019
TFDP1transcription factor Dp-10.019
SMC3structural maintenance of chromosomes 30.019
UHRF2ubiquitin-like with PHD and ring finger domains 20.018
STAG1stromal antigen 10.018
DEPDC1DEP domain containing 10.018
GAS2L3growth arrest-specific 2 like 30.017
SMC1Astructural maintenance of chromosomes 1A0.017
PMS2PMS2 postmeiotic segregation increased 2 (S. cerevisiae)0.016
RAD21RAD21 homolog (S. pombe)0.016
MBD1methyl-CpG binding domain protein 10.016
HJURPHolliday junction recognition protein0.016
SKA1spindle and kinetochore associated complex subunit 10.016
NEIL3nei endonuclease VIII-like 3 (E. coli)0.016
RRP1Bribosomal RNA processing 1 homolog B (S. cerevisiae)0.016
CHEK1CHK1 checkpoint homolog (S. pombe)0.016
AURKAaurora kinase A0.016
PAFAH1B2platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)0.015
ASPSCR1alveolar soft part sarcoma chromosome region, candidate 10.015
CDC25Ccell division cycle 25 homolog C (S. pombe)0.015
CAND1cullin-associated and neddylation-dissociated 10.015
KIF20Bkinesin family member 20B0.015
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdk1cyclin-dependent kinase 10.798
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.750
Plk1polo-like kinase 1 (Drosophila)0.628
Ccnfcyclin F0.615
Trp53transformation related protein 530.609
Dlgap5discs, large (Drosophila) homolog-associated protein 50.606
Kif2ckinesin family member 2C0.560
Gtse1G two S phase expressed protein 10.552
Ncaphnon-SMC condensin I complex, subunit H0.546
Cdc25ccell division cycle 25 homolog C (S. pombe)0.538
Prc1protein regulator of cytokinesis 10.533
Ccna2cyclin A20.531
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.440
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.432
Kif4kinesin family member 40.392
Brca1breast cancer 10.336
Aurkaaurora kinase A0.319
Rad51ap1RAD51 associated protein 10.288
Ctnnb1catenin (cadherin associated protein), beta 10.283
Mis18bp1MIS18 binding protein 10.269
Ube2cubiquitin-conjugating enzyme E2C0.266
Chek2CHK2 checkpoint homolog (S. pombe)0.255
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.244
Mcm10minichromosome maintenance deficient 10 (S. cerevisiae)0.240
Cdkn1bcyclin-dependent kinase inhibitor 1B0.237
Cenpfcentromere protein F0.235
Aurkbaurora kinase B0.234
Ccnb2cyclin B20.226
Exo1exonuclease 10.219
Zfp62zinc finger protein 620.198
Kif23kinesin family member 230.177
Mybl2myeloblastosis oncogene-like 20.176
Ckap2cytoskeleton associated protein 20.168
Kif11kinesin family member 110.162
Fam64afamily with sequence similarity 64, member A0.162
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.161
Nsfl1cNSFL1 (p97) cofactor (p47)0.151
Kif20akinesin family member 20A0.146
Hmmrhyaluronan mediated motility receptor (RHAMM)0.144
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.143
Cdk4cyclin-dependent kinase 40.130
TtkTtk protein kinase0.130
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.126
Spag5sperm associated antigen 50.126
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.125
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.121
Trip13thyroid hormone receptor interactor 130.120
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.120
Agfg1ArfGAP with FG repeats 10.119
Chaf1bchromatin assembly factor 1, subunit B (p60)0.116
Ccnb1cyclin B10.111
Cenpncentromere protein N0.107
Ccne1cyclin E10.106
Cdca5cell division cycle associated 50.104
Brca2breast cancer 20.101
Kif22kinesin family member 220.091
Tpx2TPX2, microtubule-associated protein homolog (Xenopus laevis)0.090
Eme1essential meiotic endonuclease 1 homolog 1 (S. pombe)0.086
Ptenphosphatase and tensin homolog0.083
Mns1meiosis-specific nuclear structural protein 10.082
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.080
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.079
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.077
Top2atopoisomerase (DNA) II alpha0.076
Cenpacentromere protein A0.076
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.075
Hmgb1high mobility group box 10.074
Hif1ahypoxia inducible factor 1, alpha subunit0.073
H2afxH2A histone family, member X0.073
Ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.067
Anlnanillin, actin binding protein0.066
Wdr77WD repeat domain 770.065
Iqgap3IQ motif containing GTPase activating protein 30.064
Trim23tripartite motif-containing 230.064
Gsg2germ cell-specific gene 20.060
E2f8E2F transcription factor 80.058
Cdk2cyclin-dependent kinase 20.055
Foxm1forkhead box M10.054
Rbl1retinoblastoma-like 1 (p107)0.053
Rasa1RAS p21 protein activator 10.053
Tcf12transcription factor 120.053
Zfmlzinc finger, matrin-like0.052
Cdca8cell division cycle associated 80.052
Orc1origin recognition complex, subunit 10.052
E2f1E2F transcription factor 10.051
Sgol1shugoshin-like 1 (S. pombe)0.051
Hdac2histone deacetylase 20.050
Ska1spindle and kinetochore associated complex subunit 10.049
Tcf19transcription factor 190.047
Cdca3cell division cycle associated 30.047
Cdkn3cyclin-dependent kinase inhibitor 30.047
MaxMax protein0.046
Spc24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.046
Cenpecentromere protein E0.046
C330027C09RikRIKEN cDNA C330027C09 gene0.045
Pmf1polyamine-modulated factor 10.045
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.045
Lmnb1lamin B10.045
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.044
StilScl/Tal1 interrupting locus0.044
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.388
Hmmrhyaluronan mediated motility receptor (RHAMM)0.179
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.097
Plk1polo-like kinase 1 (Drosophila)0.086
Birc5baculoviral IAP repeat-containing 50.083
Dlgap5discs, large (Drosophila) homolog-associated protein 50.077
Hdlbphigh density lipoprotein binding protein0.056
Kif2ckinesin family member 2C0.054
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.052
Cenpicentromere protein I0.050
Cul1cullin 10.042
Rad51ap1RAD51 associated protein 10.042
Ccne1cyclin E10.041
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.040
Kifc1kinesin family member C10.039
Psmd11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.039
Cdca3cell division cycle associated 30.038
Espl1extra spindle pole bodies homolog 1 (S. cerevisiae)0.035
Pttg1pituitary tumor-transforming 10.033
Troaptrophinin associated protein0.033
Rpn2ribophorin II0.031
Iqgap3IQ motif containing GTPase activating protein 30.030
LOC689399hypothetical protein LOC6893990.029
Ubqln1ubiquilin 10.029
Snd1staphylococcal nuclease and tudor domain containing 10.026
Foxm1forkhead box M10.026
Ube2tubiquitin-conjugating enzyme E2T (putative)0.024
TraipTRAF-interacting protein0.024
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.024
Timelesstimeless homolog (Drosophila)0.024
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.024
Traf4af1TRAF4 associated factor 10.023
Spag5sperm associated antigen 50.021
Cdca8cell division cycle associated 80.021
Racgap1Rac GTPase-activating protein 10.020
E2f1E2F transcription factor 10.019
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.019
Kif4kinesin family member 40.018
Cd8aCD8a molecule0.018
Rab28RAB28, member RAS oncogene family0.017
Cenptcentromere protein T0.017
Dlatdihydrolipoamide S-acetyltransferase0.016
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.016
Kif18bkinesin family member 18B0.016
Dhfrdihydrofolate reductase0.016
Kif22kinesin family member 220.016
Nrd1nardilysin 10.015
Fen1flap structure-specific endonuclease 10.015
Akap11A kinase (PRKA) anchor protein 110.015
Eif3ceukaryotic translation initiation factor 3, subunit C0.015
Rb1retinoblastoma 10.015
Rad51cRad51 homolog c (S. cerevisiae)0.015
Nr3c2nuclear receptor subfamily 3, group C, member 20.014
Ube2cubiquitin-conjugating enzyme E2C0.014
Mcm5minichromosome maintenance complex component 50.014
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.014
LOC100310874antisense RNA overlapping MCH0.013
Bard1BRCA1 associated RING domain 10.013
Fam64afamily with sequence similarity 64, member A0.013
E2f8E2F transcription factor 80.013
Melkmaternal embryonic leucine zipper kinase0.013
Nsfl1cNSFL1 (p97) cofactor (p47)0.012
Matr3matrin 30.012
RGD1304693similar to CG14803-PA0.012
Trip13thyroid hormone receptor interactor 130.012
Cenpqcentromere protein Q0.012
Pmf1polyamine-modulated factor 10.012
Zfp364zinc finger protein 3640.012
Kpna3karyopherin alpha 30.011
Cand1cullin-associated and neddylation-dissociated 10.011
Reep4receptor accessory protein 40.011
Gins4GINS complex subunit 4 (Sld5 homolog)0.011
Aurkaaurora kinase A0.011
VapaVAMP (vesicle-associated membrane protein)-associated protein A0.011
Cnot2CCR4-NOT transcription complex, subunit 20.011
Foxj3forkhead box J30.010
Xkr5XK, Kell blood group complex subunit-related family, member 50.010
Smc6structural maintenance of chromosomes 60.010
Ncapd2non-SMC condensin I complex, subunit D20.010
Aurkbaurora kinase B0.010
Ccdc72coiled-coil domain containing 720.010
Zfrzinc finger RNA binding protein0.010