The network for 'attachment of spindle microtubules to kinetochore' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

attachment of spindle microtubules to kinetochore

The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.

NameDescriptionProbabilityFunc Analog Organism
ASK1Ask1p0.998
DAM1Dam1p0.996
DAD4Dad4p0.980
DSN1Dsn1p0.978
SPC34Spc34p0.951
DAD2Dad2p0.933
MPS1Mps1p0.927
DUO1Duo1p0.903
DAD1Dad1p0.885
MTW1Mtw1p0.876
HSK3Hsk3p0.761
OKP1Okp1p0.725
SPC19Spc19p0.716
NSL1Nsl1p0.695
TID3Tid3p0.658
CSE4Cse4p0.621
CTF3Ctf3p0.608
MIF2Mif2p0.548
IML3Iml3p0.539
IPL1Ipl1p0.443
NNF1Nnf1p0.369
MCM21Mcm21p0.360
DAD3Dad3p0.317
SLI15Sli15p0.313
NUF2Nuf2p0.280
CHL4Chl4p0.269
SPC98Spc98p0.259
YBP2Ybp2p0.256
CKS1Cks1p0.250
SPC24Spc24p0.247
KIP1Kip1p0.239
MCM22Mcm22p0.221
CLB6Clb6p0.209
AME1Ame1p0.169
NBL1Nbl1p0.111
SPC25Spc25p0.111
SPC97Spc97p0.102
CLB5Clb5p0.096
MAD2Mad2p0.084
CLN1Cln1p0.071
BUB3Bub3p0.068
SHE1She1p0.063
YCK1Yck1p0.059
VIK1Vik1p0.057
YPL014Whypothetical protein0.057
KAR3Kar3p0.053
CDC4Cdc4p0.051
NKP2Nkp2p0.050
CLU1Clu1p0.047
STU2Stu2p0.043
MAD1Mad1p0.041
SPC110Spc110p0.041
CTF19Ctf19p0.038
BUB1Bub1p0.037
CNN1Cnn1p0.035
NKP1Nkp1p0.032
CIK1Cik1p0.031
CIN2Cin2p0.031
SPC105Spc105p0.027
YIL151Chypothetical protein0.027
KAR9Kar9p0.027
CHL1Chl1p0.027
NUP49Nup49p0.026
CLN2Cln2p0.026
CDC6Cdc6p0.025
SFB2Sfb2p0.025
YLR264C-Ahypothetical protein0.025
CDC48Cdc48p0.024
MCM16Mcm16p0.023
SRD1Srd1p0.023
CLB1Clb1p0.021
FIN1Fin1p0.021
GNA1Gna1p0.020
STU1Stu1p0.020
SLK19Slk19p0.020
YNL058Chypothetical protein0.020
CDC20Cdc20p0.020
KTI11Kti11p0.020
YLR162Whypothetical protein0.019
LEU2Leu2p0.019
BIM1Bim1p0.019
SRO77Sro77p0.019
PCC1Pcc1p0.019
CBF2Cbf2p0.018
CLB4Clb4p0.018
CBF1Cbf1p0.018
YOL038C-Ahypothetical protein0.018
YAR068Whypothetical protein0.018
PPH21Pph21p0.018
CRP1Crp1p0.018
NUP157Nup157p0.017
ARP10Arp10p0.017
ARE2Are2p0.017
CDC28Cdc28p0.017
LCB4Lcb4p0.017
STB1Stb1p0.017
VAC17Vac17p0.017
URA3Ura3p0.016
MER1Mer1p0.016
YPL216Whypothetical protein0.016
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mcm-7Protein MCM-70.864
hcp-1Protein HCP-10.829
hcp-4Protein HCP-40.736
klp-19Protein KLP-190.712
knl-1Protein KNL-10.709
bub-1Protein BUB-10.614
him-10Protein HIM-100.606
cyk-4Protein CYK-40.566
hcp-2Protein HCP-20.485
mcm-3Protein MCM-30.433
bmk-1Protein BMK-10.380
htz-1Protein HTZ-10.311
gpr-1Protein GPR-10.254
F33H2.5Protein F33H2.50.251
CELE_R06A4.2Protein R06A4.20.241
air-2Protein AIR-20.237
ubxn-4Protein UBXN-40.223
scc-1Protein SCC-10.221
T27A3.2Protein T27A3.20.217
tbb-1Protein TBB-10.214
CELE_C39E9.12Protein C39E9.120.192
isw-1Protein ISW-10.181
rnr-1Protein RNR-10.167
npp-3Protein NPP-30.154
CELE_Y53F4B.9Protein Y53F4B.90.149
smc-6Protein SMC-60.128
icp-1Protein ICP-10.127
aspm-1Protein ASPM-10.114
pcn-1Protein PCN-10.107
puf-6Protein PUF-60.104
mel-28Protein MEL-280.103
cin-4Protein CIN-40.098
zen-4Protein ZEN-40.092
hcp-6Protein HCP-60.084
flh-1Protein FLH-10.082
cyb-2.2Protein CYB-2.20.080
cls-2Protein CLS-20.079
hil-4Protein HIL-40.077
lst-3Protein LST-30.073
gpd-4Protein GPD-40.072
sas-5Protein SAS-50.067
wee-1.3Protein WEE-1.30.066
F17A9.2Protein F17A9.20.066
air-1Protein AIR-10.065
hmg-1.2Protein HMG-1.20.062
ndc-80Protein NDC-800.062
knl-3Protein KNL-30.061
fzy-1Protein FZY-10.060
dsh-2Protein DSH-20.060
ubxn-1Protein UBXN-10.057
spk-1Protein SPK-10.050
hgrs-1Protein HGRS-10.050
puf-7Protein PUF-70.048
F56D2.6Protein F56D2.60.048
cdl-1Protein CDL-10.045
CELE_F59A6.5Protein F59A6.50.045
lin-5Protein LIN-50.045
tba-2Protein TBA-20.043
T24H10.1Protein T24H10.10.040
cpg-1Protein CPG-10.040
hpo-9Protein HPO-90.039
mcm-5Protein MCM-50.039
top-2Protein TOP-20.037
prp-3Protein PRP-30.036
lin-13Protein LIN-130.036
emb-27Protein EMB-270.035
smc-4Protein SMC-40.034
T07C4.10Protein T07C4.100.033
rsa-1Protein RSA-10.030
clec-87Protein CLEC-870.029
B0491.1Protein B0491.10.029
atl-1Protein ATL-10.029
crn-1Protein CRN-10.028
mcm-2Protein MCM-20.028
pis-1Protein PIS-10.026
tbb-2Protein TBB-20.026
Y4C6B.1Protein Y4C6B.10.026
cyk-7Protein CYK-70.025
npp-9Protein NPP-90.023
T20B12.3Protein T20B12.30.023
cyb-1Protein CYB-10.023
F59G1.8Protein F59G1.80.022
nasp-2Protein NASP-20.022
F54E12.2Protein F54E12.20.022
pri-2Protein PRI-20.022
klp-7Protein KLP-70.022
kup-1Protein KUP-10.022
D2045.2Protein D2045.20.021
C50F2.3Protein C50F2.30.021
F10C2.4Protein F10C2.40.021
orc-5Protein ORC-50.021
zyg-9Protein ZYG-90.020
spd-1Protein SPD-10.020
T19H12.2Protein T19H12.20.019
ima-3Protein IMA-30.019
T08B2.11Protein T08B2.110.018
prp-8Protein PRP-80.018
W02D9.2Protein W02D9.20.018
acs-4Protein ACS-40.017
mcm-6Protein MCM-60.017
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CycBCyclin B0.772
pavpavarotti0.710
ncdnon-claret disjunctional0.580
CycB3Cyclin B30.281
scrascraps0.251
tumtumbleweed0.235
marsCG17064 gene product from transcript CG17064-RB0.217
aslasterless0.136
CycACyclin A0.135
Nek2CG17256 gene product from transcript CG17256-RA0.130
aspabnormal spindle0.126
stgstring0.112
pblpebble0.098
Klp61FKinesin-like protein at 61F0.074
Klp10ACG1453 gene product from transcript CG1453-RA0.071
thrthree rows0.065
dupdouble parked0.063
IncenpInner centromere protein0.061
rokRho-kinase0.058
cmetCENP-meta0.055
swaswallow0.054
spd-2spindle defective 20.050
Src64BSrc oncogene at 64B0.048
cnncentrosomin0.047
ana3anastral spindle 30.047
twetwine0.043
Sas-4CG10061 gene product from transcript CG10061-RA0.042
fzfrizzled0.034
gwlgreatwall0.034
AblAbl tyrosine kinase0.033
chbchromosome bows0.030
enaenabled0.029
Cap-GCG34438 gene product from transcript CG34438-RF0.027
Grip128CG9201 gene product from transcript CG9201-RB0.026
ballballchen0.026
Syx1ASyntaxin 1A0.024
cidcentromere identifier0.023
rapretina aberrant in pattern0.023
Rab5Rab-protein 50.022
Cks30ACyclin-dependent kinase subunit 30A0.021
MedMedea0.021
Cenp-CCG31258 gene product from transcript CG31258-RA0.021
aopanterior open0.019
larpLa related protein0.019
mtsmicrotubule star0.018
Poc1Proteome of centrioles 10.018
trbltribbles0.017
Fs(2)KetFemale sterile (2) Ketel0.017
pUf68poly U binding factor 68kD0.017
BubR1Bub1-related kinase0.016
Cep135CG17081 gene product from transcript CG17081-RB0.016
LBRLamin B receptor0.016
MerMerlin0.015
Tao-1CG14217 gene product from transcript CG14217-RF0.015
Df31Decondensation factor 310.015
Cdc37CG12019 gene product from transcript CG12019-RA0.014
alphaTub67Calpha-Tubulin at 67C0.014
mei-P26CG12218 gene product from transcript CG12218-RA0.014
nebnebbish0.013
vtdverthandi0.013
Spc105RSpc105-related0.013
poloCG12306 gene product from transcript CG12306-RA0.012
wispwispy0.012
feofascetto0.012
ana2anastral spindle 20.012
CG4680CG4680 gene product from transcript CG4680-RA0.011
Mi-2CG8103 gene product from transcript CG8103-RA0.011
katanin-60katanin 600.011
slprslipper0.011
Pp2B-14DProtein phosphatase 2B at 14D0.011
atmsantimeros0.011
piepineapple eye0.010
pngpan gu0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.994
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.988
RB1retinoblastoma 10.952
CDC20cell division cycle 20 homolog (S. cerevisiae)0.944
AURKBaurora kinase B0.912
RACGAP1Rac GTPase activating protein 10.904
CBX5chromobox homolog 50.862
ZWINTZW10 interactor0.830
NCAPD2non-SMC condensin I complex, subunit D20.689
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.673
CCNB1cyclin B10.611
CENPEcentromere protein E, 312kDa0.608
RBL1retinoblastoma-like 1 (p107)0.510
CCNA2cyclin A20.491
PRC1protein regulator of cytokinesis 10.455
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.377
TTKTTK protein kinase0.371
CASC5cancer susceptibility candidate 50.355
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.346
HMMRhyaluronan-mediated motility receptor (RHAMM)0.324
CDCA8cell division cycle associated 80.311
CDK1cyclin-dependent kinase 10.306
SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.283
KIF20Akinesin family member 20A0.256
KIF23kinesin family member 230.255
CKS2CDC28 protein kinase regulatory subunit 20.241
CDK2cyclin-dependent kinase 20.225
NCAPG2non-SMC condensin II complex, subunit G20.224
INCENPinner centromere protein antigens 135/155kDa0.215
VCPvalosin containing protein0.196
PLK1polo-like kinase 10.193
KIF14kinesin family member 140.162
ECT2epithelial cell transforming sequence 2 oncogene0.149
CDC27cell division cycle 27 homolog (S. cerevisiae)0.130
CDKN3cyclin-dependent kinase inhibitor 30.125
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.121
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.117
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.110
NEK2NIMA (never in mitosis gene a)-related kinase 20.110
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.101
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.098
KIF18Akinesin family member 18A0.094
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.093
DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)0.087
SPC24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.084
KIF1Bkinesin family member 1B0.080
MPHOSPH9M-phase phosphoprotein 90.069
CDCA2cell division cycle associated 20.057
NUP85nucleoporin 85kDa0.052
DVL3dishevelled, dsh homolog 3 (Drosophila)0.050
TUBB2Ctubulin, beta 2C0.049
NUP133nucleoporin 133kDa0.049
CEBPECCAAT/enhancer binding protein (C/EBP), epsilon0.048
SKA1spindle and kinetochore associated complex subunit 10.048
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.048
ZW10ZW10, kinetochore associated, homolog (Drosophila)0.047
AURKAaurora kinase A0.047
YTHDC2YTH domain containing 20.047
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.047
SGOL2shugoshin-like 2 (S. pombe)0.043
CEP55centrosomal protein 55kDa0.041
DLGAP5discs, large (Drosophila) homolog-associated protein 50.041
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.040
MIS12MIS12, MIND kinetochore complex component, homolog (S. pombe)0.038
MKI67antigen identified by monoclonal antibody Ki-670.037
CKAP5cytoskeleton associated protein 50.033
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.033
MDM4Mdm4 p53 binding protein homolog (mouse)0.033
ARL6IP1ADP-ribosylation factor-like 6 interacting protein 10.032
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.031
ZNF207zinc finger protein 2070.031
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.029
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.029
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.029
RANBP9RAN binding protein 90.028
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.028
STILSCL/TAL1 interrupting locus0.027
CCNB2cyclin B20.027
TRIP13thyroid hormone receptor interactor 130.026
CDC6cell division cycle 6 homolog (S. cerevisiae)0.026
E2F5E2F transcription factor 5, p130-binding0.026
DNA2DNA replication helicase 2 homolog (yeast)0.026
ANAPC1anaphase promoting complex subunit 10.026
RRM2ribonucleotide reductase M20.025
TMEM48transmembrane protein 480.024
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.024
NCAPD3non-SMC condensin II complex, subunit D30.023
WDR67WD repeat domain 670.023
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.023
TDP1tyrosyl-DNA phosphodiesterase 10.023
AXIN1axin 10.022
LIN54lin-54 homolog (C. elegans)0.022
SMC2structural maintenance of chromosomes 20.022
HNRNPMheterogeneous nuclear ribonucleoprotein M0.022
AKT1v-akt murine thymoma viral oncogene homolog 10.022
RBBP8retinoblastoma binding protein 80.021
GPSM2G-protein signaling modulator 20.021
WDHD1WD repeat and HMG-box DNA binding protein 10.021
SMC4structural maintenance of chromosomes 40.020
CDC42EP3CDC42 effector protein (Rho GTPase binding) 30.020
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.981
Ccnb2cyclin B20.956
Prc1protein regulator of cytokinesis 10.837
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.775
Kif20akinesin family member 20A0.684
Ccnb1cyclin B10.674
Cdk1cyclin-dependent kinase 10.644
Rad51ap1RAD51 associated protein 10.614
Ccna2cyclin A20.610
Ube2cubiquitin-conjugating enzyme E2C0.602
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.573
Trp53transformation related protein 530.562
StilScl/Tal1 interrupting locus0.503
C330027C09RikRIKEN cDNA C330027C09 gene0.487
Kif4kinesin family member 40.469
Hmmrhyaluronan mediated motility receptor (RHAMM)0.465
Anlnanillin, actin binding protein0.449
Aurkbaurora kinase B0.438
Plk4polo-like kinase 4 (Drosophila)0.420
Aurkaaurora kinase A0.414
Ckap2cytoskeleton associated protein 20.384
Kif11kinesin family member 110.352
Brca1breast cancer 10.345
Plk1polo-like kinase 1 (Drosophila)0.338
Cdkn1bcyclin-dependent kinase inhibitor 1B0.334
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.332
Per2period homolog 2 (Drosophila)0.327
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.304
Kif22kinesin family member 220.265
Mki67antigen identified by monoclonal antibody Ki 670.257
Spag5sperm associated antigen 50.243
Per1period homolog 1 (Drosophila)0.233
Cdkn3cyclin-dependent kinase inhibitor 30.231
Cenpfcentromere protein F0.226
Ptenphosphatase and tensin homolog0.219
Nf2neurofibromatosis 20.219
Gsk3bglycogen synthase kinase 3 beta0.215
Rac1RAS-related C3 botulinum substrate 10.201
Tmpothymopoietin0.194
Ccdc99coiled-coil domain containing 990.193
Kif2ckinesin family member 2C0.191
Birc5baculoviral IAP repeat-containing 50.189
Cdc25ccell division cycle 25 homolog C (S. pombe)0.189
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.182
Mdm2transformed mouse 3T3 cell double minute 20.179
Cep55centrosomal protein 550.169
Depdc1aDEP domain containing 1a0.152
Top2atopoisomerase (DNA) II alpha0.149
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.146
Smad4MAD homolog 4 (Drosophila)0.144
Ncaphnon-SMC condensin I complex, subunit H0.140
Gsg2germ cell-specific gene 20.135
Brca2breast cancer 20.131
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.130
Smc4structural maintenance of chromosomes 40.127
Trim59tripartite motif-containing 590.125
Ncapgnon-SMC condensin I complex, subunit G0.112
Cenpncentromere protein N0.112
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.106
Cdca8cell division cycle associated 80.103
PbkPDZ binding kinase0.099
Gnb2guanine nucleotide binding protein (G protein), beta 20.099
Ect2ect2 oncogene0.097
Cenpecentromere protein E0.091
Dctn1dynactin 10.088
Dlgap5discs, large (Drosophila) homolog-associated protein 50.084
Racgap1Rac GTPase-activating protein 10.079
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.078
Kif23kinesin family member 230.074
Kitkit oncogene0.073
Nsfl1cNSFL1 (p97) cofactor (p47)0.072
Ncapg2non-SMC condensin II complex, subunit G20.069
Psen1presenilin 10.067
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.067
Ube2tubiquitin-conjugating enzyme E2T (putative)0.066
Nusap1nucleolar and spindle associated protein 10.065
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.065
Axin1axin 10.064
Eri2exoribonuclease 20.064
Men1multiple endocrine neoplasia 10.064
Hif1ahypoxia inducible factor 1, alpha subunit0.064
Sass6spindle assembly 6 homolog (C. elegans)0.063
Tpx2TPX2, microtubule-associated protein homolog (Xenopus laevis)0.061
Incenpinner centromere protein0.060
Ezh2enhancer of zeste homolog 2 (Drosophila)0.060
Tacc3transforming, acidic coiled-coil containing protein 30.058
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.056
Lmnb1lamin B10.056
Cry2cryptochrome 2 (photolyase-like)0.056
Mns1meiosis-specific nuclear structural protein 10.055
Kif18akinesin family member 18A0.055
Anapc2anaphase promoting complex subunit 20.054
Diap3diaphanous homolog 3 (Drosophila)0.054
Chukconserved helix-loop-helix ubiquitous kinase0.053
Arntlaryl hydrocarbon receptor nuclear translocator-like0.053
BrafBraf transforming gene0.053
Ccnfcyclin F0.053
Ccnd1cyclin D10.052
Ube4bubiquitination factor E4B, UFD2 homolog (S. cerevisiae)0.051
H2afxH2A histone family, member X0.051
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism