The network for 'synaptonemal complex assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

synaptonemal complex assembly

The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.

NameDescriptionProbabilityFunc Analog Organism
ZIP1Zip1p0.913
RED1Red1p0.874
MEK1Mek1p0.586
PCH2Pch2p0.294
SMC4Smc4p0.207
SPO11Spo11p0.205
NDT80Ndt80p0.192
BRN1Brn1p0.180
MND1Mnd1p0.174
CST9Cst9p0.169
IME2Ime2p0.154
HOP1Hop1p0.153
MSH4Msh4p0.132
HFM1Hfm1p0.112
ZIP2Zip2p0.107
PDS1Pds1p0.105
SPO22Spo22p0.054
DMC1Dmc1p0.053
SMC2Smc2p0.045
MSH5Msh5p0.041
PDS5Pds5p0.036
CSM4Csm4p0.035
HSL1Hsl1p0.035
ECM11Ecm11p0.033
MAM1Mam1p0.032
SRD1Srd1p0.024
CLB6Clb6p0.023
LEU2Leu2p0.023
MCD1Mcd1p0.022
REC104Rec104p0.021
HOP2Hop2p0.021
REC102Rec102p0.021
ZPS1Zps1p0.020
ARP10Arp10p0.020
YLR162Whypothetical protein0.020
YLR264C-Ahypothetical protein0.020
YOL038C-Ahypothetical protein0.020
SPC42Spc42p0.019
MER1Mer1p0.019
NUP82Nup82p0.019
GLG2Glg2p0.019
SPO16Spo16p0.018
CAK1Cak1p0.018
GAL2Gal2p0.018
CHA1Cha1p0.018
CUP1-1Cup1-1p0.017
IME4Ime4p0.017
SPL2Spl2p0.017
HXT3Hxt3p0.016
PTI1Pti1p0.016
CDC20Cdc20p0.016
PCL9Pcl9p0.016
SPR3Spr3p0.016
YIL151Chypothetical protein0.016
YAR068Whypothetical protein0.015
ORC6Orc6p0.015
ATP6Atp6p0.015
SSP1Ssp1p0.015
SAE3Sae3p0.015
SRT1Srt1p0.015
YPR157Whypothetical protein0.015
YBR013Chypothetical protein0.015
RAD53Rad53p0.015
RNP1Rnp1p0.015
MEI4Mei4p0.014
YBL044Whypothetical protein0.014
YOL013W-Ahypothetical protein0.014
YLR042Chypothetical protein0.014
SHU1Shu1p0.014
PCL10Pcl10p0.014
HPF1Hpf1p0.014
SPO13Spo13p0.014
ARG8Arg8p0.014
CSM3Csm3p0.013
OPT2Opt2p0.013
YJL181Whypothetical protein0.013
AUA1Aua1p0.013
SPS4Sps4p0.013
KNH1Knh1p0.013
ICS2Ics2p0.013
CPD1Cpd1p0.013
CLB1Clb1p0.013
YGL081Whypothetical protein0.013
EST2Est2p0.013
SPO74Spo74p0.013
IZH4Izh4p0.013
YOR365Chypothetical protein0.013
SCC2Scc2p0.013
YML053Chypothetical protein0.012
YCG1Ycg1p0.012
URA3Ura3p0.012
ALT2Alt2p0.012
COS12Cos12p0.012
AQY2Aqy2p0.012
YGL015Chypothetical protein0.012
BBP1Bbp1p0.012
HST3Hst3p0.012
YKR075Chypothetical protein0.012
FMT1Fmt1p0.012
DIC1Dic1p0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ucr-2.3Protein UCR-2.30.456
htp-1Protein HTP-10.312
duo-1Protein DUO-10.248
F13D12.5Protein F13D12.50.194
glh-3Protein GLH-30.165
hpo-32Protein HPO-320.127
him-3Protein HIM-30.124
D1081.7Protein D1081.70.122
F09G2.2Protein F09G2.20.109
rfc-4Protein RFC-40.095
iff-1Protein IFF-10.093
mcm-5Protein MCM-50.090
klp-7Protein KLP-70.086
W03G9.3Protein W03G9.30.085
ZC410.3Protein ZC410.30.085
K11H3.4Protein K11H3.40.082
pgl-1Protein PGL-10.077
ZK678.3Protein ZK678.30.077
got-2.1Protein GOT-2.10.077
mre-11Protein MRE-110.077
vha-18Protein VHA-180.074
zen-4Protein ZEN-40.071
wago-1Protein WAGO-10.071
T28A8.6Protein T28A8.60.070
immt-2Protein IMMT-20.069
bub-1Protein BUB-10.067
ife-3Protein IFE-30.062
F58E10.3Protein F58E10.30.060
elpc-3Protein ELPC-30.058
csr-1Protein CSR-10.058
D2005.4Protein D2005.40.053
nxf-2Protein NXF-20.053
ZC434.8Protein ZC434.80.052
san-1Protein SAN-10.052
zim-3Protein ZIM-30.052
mcm-6Protein MCM-60.052
cyk-1Protein CYK-10.050
skr-17Protein SKR-170.048
plk-1Protein PLK-10.047
cyk-4Protein CYK-40.046
csc-1Protein CSC-10.046
smc-5Protein SMC-50.043
C55B7.11Protein C55B7.110.042
W03C9.2Protein W03C9.20.041
F56C9.6Protein F56C9.60.041
C48B4.10Protein C48B4.100.041
glh-1Protein GLH-10.041
CELE_W02A11.1Protein W02A11.10.041
C05C10.2Protein C05C10.20.040
npp-18Protein NPP-180.040
F01G4.4Protein F01G4.40.040
F20A1.9Protein F20A1.90.039
C13B4.1Protein C13B4.10.039
skr-2Protein SKR-20.039
ppw-2Protein PPW-20.038
T10F2.2Protein T10F2.20.036
F33D11.10Protein F33D11.100.034
ZK418.8Protein ZK418.80.033
CELE_T02C12.3Protein T02C12.30.032
R07B7.2Protein R07B7.20.031
CELE_C38D4.4Protein C38D4.40.031
rnp-8Protein RNP-80.030
K09H9.7Protein K09H9.70.030
set-22Protein SET-220.029
F55G1.5Protein F55G1.50.029
CELE_D1046.2Protein D1046.20.028
ect-2Protein ECT-20.027
F35G12.5Protein F35G12.50.026
CELE_C34D4.10Protein C34D4.100.026
C48B4.6Protein C48B4.60.026
lst-3Protein LST-30.023
glh-4Protein GLH-40.023
fbxa-101Protein FBXA-1010.023
hil-5Protein HIL-50.023
CELE_C24H12.5Protein C24H12.50.022
F57A10.4Protein F57A10.40.022
K01G5.5Protein K01G5.50.022
CELE_C56A3.8Protein C56A3.80.022
pgl-2Protein PGL-20.022
mrp-7Protein MRP-70.021
F21F3.4Protein F21F3.40.021
hcf-1Protein HCF-10.021
K08E3.4Protein K08E3.40.020
toe-1Protein TOE-10.020
klp-18Protein KLP-180.020
T02G5.12Protein T02G5.120.020
T12F5.2Protein T12F5.20.019
gpd-4Protein GPD-40.019
CELE_C29A12.1Protein C29A12.10.018
syx-4Protein SYX-40.018
C18A3.2Protein C18A3.20.018
asb-1Protein ASB-10.018
brc-1Protein BRC-10.017
bath-42Protein BATH-420.017
prg-2Protein PRG-20.017
gop-2Protein GOP-20.017
T19H12.2Protein T19H12.20.017
cpb-1Protein CPB-10.017
inx-21Protein INX-210.016
C46A5.6Protein C46A5.60.016
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccna2cyclin A20.990
Ccnb1cyclin B10.957
Smc1astructural maintenance of chromosomes 1A0.917
Mecp2methyl CpG binding protein 20.869
Prc1protein regulator of cytokinesis 10.500
Birc5baculoviral IAP repeat-containing 50.478
Ccnb2cyclin B20.448
Kif20akinesin family member 20A0.329
Ncaphnon-SMC condensin I complex, subunit H0.308
Ccne1cyclin E10.275
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.268
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.221
Ckap2cytoskeleton associated protein 20.220
Rrm2ribonucleotide reductase M20.208
Kif11kinesin family member 110.189
Neurl1aneuralized homolog 1A (Drosophila)0.153
Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.144
Nxf2nuclear RNA export factor 20.135
Pole2polymerase (DNA directed), epsilon 2 (p59 subunit)0.135
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.134
Cks2CDC28 protein kinase regulatory subunit 20.128
Naspnuclear autoantigenic sperm protein (histone-binding)0.115
Top2atopoisomerase (DNA) II alpha0.113
2810417H13RikRIKEN cDNA 2810417H13 gene0.110
Gnb2guanine nucleotide binding protein (G protein), beta 20.109
Ppihpeptidyl prolyl isomerase H0.109
Kif23kinesin family member 230.097
Pcnaproliferating cell nuclear antigen0.083
Ptov1prostate tumor over expressed gene 10.082
Csnk1g2casein kinase 1, gamma 20.080
Cdca8cell division cycle associated 80.074
Cdk2cyclin-dependent kinase 20.069
Smc2structural maintenance of chromosomes 20.068
Ints9integrator complex subunit 90.068
Cpeb2cytoplasmic polyadenylation element binding protein 20.066
Aurkaaurora kinase A0.065
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.064
Racgap1Rac GTPase-activating protein 10.063
Cdk1cyclin-dependent kinase 10.063
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.062
Usp21ubiquitin specific peptidase 210.057
C330027C09RikRIKEN cDNA C330027C09 gene0.057
Cdca7cell division cycle associated 70.054
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.051
Tsc2tuberous sclerosis 20.049
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.047
Kif22kinesin family member 220.047
Dctn1dynactin 10.047
Plk4polo-like kinase 4 (Drosophila)0.046
Rnf2ring finger protein 20.045
Ldb1LIM domain binding 10.042
Supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.041
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.041
Stk31serine threonine kinase 310.040
Hmgb2high mobility group box 20.040
PbkPDZ binding kinase0.039
Kif1bkinesin family member 1B0.038
Rnf11ring finger protein 110.036
Aurkbaurora kinase B0.035
Med16mediator complex subunit 160.035
Cdk4cyclin-dependent kinase 40.033
Tk1thymidine kinase 10.032
Melkmaternal embryonic leucine zipper kinase0.031
Fam126bfamily with sequence similarity 126, member B0.031
Adcy9adenylate cyclase 90.031
Ube2cubiquitin-conjugating enzyme E2C0.031
Tmpothymopoietin0.031
Cdca5cell division cycle associated 50.031
Vps16vacuolar protein sorting 16 (yeast)0.031
Sycp2synaptonemal complex protein 20.031
Tesk1testis specific protein kinase 10.030
Ccdc99coiled-coil domain containing 990.030
Dlgap5discs, large (Drosophila) homolog-associated protein 50.030
Rrm1ribonucleotide reductase M10.030
Skiv2lsuperkiller viralicidic activity 2-like (S. cerevisiae)0.030
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.029
Dnmt3aDNA methyltransferase 3A0.029
Vps72vacuolar protein sorting 72 (yeast)0.028
Mki67antigen identified by monoclonal antibody Ki 670.027
Aampangio-associated migratory protein0.027
Rbck1RanBP-type and C3HC4-type zinc finger containing 10.026
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.025
Cpeb4cytoplasmic polyadenylation element binding protein 40.025
Eea1early endosome antigen 10.025
RybpRING1 and YY1 binding protein0.025
Plk1polo-like kinase 1 (Drosophila)0.025
Rad51RAD51 homolog (S. cerevisiae)0.024
Anlnanillin, actin binding protein0.024
Mre11ameiotic recombination 11 homolog A (S. cerevisiae)0.024
Cenphcentromere protein H0.024
2610039C10RikRIKEN cDNA 2610039C10 gene0.023
Samd8sterile alpha motif domain containing 80.023
Trim59tripartite motif-containing 590.023
Coro1bcoronin, actin binding protein 1B0.023
Dna2DNA replication helicase 2 homolog (yeast)0.023
Kif2ckinesin family member 2C0.022
Prpf8pre-mRNA processing factor 80.021
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.021
Tex12testis expressed gene 120.021
Hnrnplheterogeneous nuclear ribonucleoprotein L0.021
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism