The network for 'histone ubiquitination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone ubiquitination

The modification of histones by addition of ubiquitin groups.

NameDescriptionProbabilityFunc Analog Organism
RTF1Rtf1p0.709
CTR9Ctr9p0.271
PAF1Paf1p0.226
LEO1Leo1p0.224
PEP3Pep3p0.065
SPT16Spt16p0.062
SPT8Spt8p0.056
SPT5Spt5p0.051
PEX22Pex22p0.047
DST1Dst1p0.044
VPS9Vps9p0.042
VPS16Vps16p0.042
TRA1Tra1p0.039
NGG1Ngg1p0.038
HDA2Hda2p0.037
SET2Set2p0.035
SGV1Sgv1p0.028
SPT7Spt7p0.026
SAP190Sap190p0.026
CAB3Cab3p0.025
SGF73Sgf73p0.024
CDC53Cdc53p0.024
HPR1Hpr1p0.022
SPT20Spt20p0.022
MRS6Mrs6p0.019
RAD6Rad6p0.018
SRD1Srd1p0.018
RPO21Rpo21p0.017
UBP3Ubp3p0.017
CUP1-1Cup1-1p0.016
MMS1Mms1p0.016
UFD2Ufd2p0.016
RCO1Rco1p0.016
LEU2Leu2p0.015
YOL038C-Ahypothetical protein0.015
YLR162Whypothetical protein0.015
HRB1Hrb1p0.015
YLR264C-Ahypothetical protein0.015
ARP10Arp10p0.014
SWD1Swd1p0.014
YBL086Chypothetical protein0.014
MER1Mer1p0.014
TOP1Top1p0.014
HXT3Hxt3p0.014
PDE2Pde2p0.014
HOHop0.014
UBC4Ubc4p0.014
CTK2Ctk2p0.014
MOT2Mot2p0.014
CHA1Cha1p0.013
CRP1Crp1p0.013
PEX19Pex19p0.013
YBR013Chypothetical protein0.013
YAR068Whypothetical protein0.013
YPR157Whypothetical protein0.013
VAB2Vab2p0.013
PRS2Prs2p0.013
KIC1Kic1p0.012
ATP6Atp6p0.012
SPL2Spl2p0.012
VPS64Vps64p0.012
ARG8Arg8p0.012
FAR11Far11p0.012
UBR1Ubr1p0.012
SPT3Spt3p0.012
URA3Ura3p0.012
SWI1Swi1p0.012
ZPS1Zps1p0.012
TYE7Tye7p0.012
YLR042Chypothetical protein0.012
HPF1Hpf1p0.012
HFI1Hfi1p0.012
YPL168Whypothetical protein0.012
GPX2Gpx2p0.012
RAD23Rad23p0.012
CDC4Cdc4p0.012
MOT1Mot1p0.012
FMT1Fmt1p0.012
BAT2Bat2p0.012
TOR1Tor1p0.011
YNL234Whypothetical protein0.011
AUA1Aua1p0.011
CPD1Cpd1p0.011
SWR1Swr1p0.011
PEX2Pex2p0.011
NOP10Nop10p0.011
YIL151Chypothetical protein0.011
YJL181Whypothetical protein0.011
YML003Whypothetical protein0.011
SPT2Spt2p0.011
OPT2Opt2p0.011
YPL216Whypothetical protein0.011
RNR2Rnr2p0.011
TFA1Tfa1p0.011
SUB1Sub1p0.011
UPS3Ups3p0.011
BSC1Bsc1p0.011
ADH2Adh2p0.011
SPT6Spt6p0.011
SCM4Scm4p0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
npp-21Protein NPP-210.023
mtk-1Protein MTK-10.022
C44E4.1Protein C44E4.10.021
bet-2Protein BET-20.012
let-418Protein LET-4180.011
F53B1.2Protein F53B1.20.011
ebp-2Protein EBP-20.011
daf-21Protein DAF-210.011
F33G12.5Protein F33G12.50.010
pqn-65Protein PQN-650.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
E(z)Enhancer of zeste0.195
ash1absent, small, or homeotic discs 10.139
ScmSex comb on midleg0.097
PcPolycomb0.038
PclPolycomblike0.032
Nedd8CG10679 gene product from transcript CG10679-RA0.031
enokenoki mushroom0.031
AGO1Argonaute-10.029
kiskismet0.029
Pp1-87BProtein phosphatase 1 at 87B0.029
BRWD3CG31132 gene product from transcript CG31132-RA0.028
SceSex combs extra0.028
Rpn6Proteasome p44.5 subunit0.026
sxcsuper sex combs0.025
msl-3male-specific lethal 30.025
matsmob as tumor suppressor0.024
cgcombgap0.024
rowrelative of woc0.021
kenken and barbie0.020
Atx2Ataxin-20.019
SmrSmrter0.018
Uba1Ubiquitin activating enzyme 10.017
CG6359CG6359 gene product from transcript CG6359-RA0.016
Dcr-1Dicer-10.016
CG7518CG7518 gene product from transcript CG7518-RD0.016
tlkTousled-like kinase0.016
RYBPRing and YY1 Binding Protein0.015
Hr39Hormone receptor-like in 390.014
Su(z)12CG8013 gene product from transcript CG8013-RA0.014
lin19lin-19-like0.014
arrarrow0.014
ApepPAminopeptidase P0.014
fdlfused lobes0.014
gppgrappa0.013
CkIalphaCasein kinase Ialpha0.013
CSN8COP9 complex homolog subunit 80.013
eastenhanced adult sensory threshold0.013
CG31224CG31224 gene product from transcript CG31224-RA0.013
brmbrahma0.013
calypsoCG8445 gene product from transcript CG8445-RB0.012
CG6734CG6734 gene product from transcript CG6734-RA0.012
droshaCG8730 gene product from transcript CG8730-RA0.012
wlswntless0.011
mldmolting defective0.011
SsdpSequence-specific single-stranded DNA-binding protein0.011
cbxcrossbronx0.011
CG4567CG4567 gene product from transcript CG4567-RA0.011
ykiyorkie0.011
lacklethal with a checkpoint kinase0.011
SbfSET domain binding factor0.010
Su(var)3-7Suppressor of variegation 3-70.010
eIF-1AEukaryotic initiation factor 1A0.010
CG7065CG7065 gene product from transcript CG7065-RA0.010
CG9063CG9063 gene product from transcript CG9063-RA0.010
effeffete0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
USP7ubiquitin specific peptidase 7 (herpes virus-associated)1.000
RING1ring finger protein 11.000
RNF2ring finger protein 21.000
RNF11ring finger protein 111.000
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.999
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.998
RNF5ring finger protein 50.998
PCGF2polycomb group ring finger 20.992
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.990
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.990
CBX8chromobox homolog 80.987
BMI1BMI1 polycomb ring finger oncogene0.985
BCORBCL6 corepressor0.983
CBX4chromobox homolog 40.976
UBE2E1ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)0.972
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.957
EEDembryonic ectoderm development0.953
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.940
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.929
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.919
CBX7chromobox homolog 70.895
ZNRF1zinc and ring finger 10.876
USP11ubiquitin specific peptidase 110.846
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.829
PCGF1polycomb group ring finger 10.812
CUL1cullin 10.795
MARCH7membrane-associated ring finger (C3HC4) 70.766
CBX6chromobox homolog 60.696
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.674
MDC1mediator of DNA-damage checkpoint 10.661
KPNA1karyopherin alpha 1 (importin alpha 5)0.607
RYBPRING1 and YY1 binding protein0.601
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.593
UBXN7UBX domain protein 70.497
YY1YY1 transcription factor0.446
TRIM39tripartite motif containing 390.441
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.421
CHFRcheckpoint with forkhead and ring finger domains0.419
UBE2E2ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)0.412
XIAPX-linked inhibitor of apoptosis0.372
PARP9poly (ADP-ribose) polymerase family, member 90.358
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.350
VPRBPVpr (HIV-1) binding protein0.325
PCGF3polycomb group ring finger 30.296
UBA1ubiquitin-like modifier activating enzyme 10.279
TCEA1transcription elongation factor A (SII), 10.278
DAXXdeath-domain associated protein0.252
DZIP3DAZ interacting protein 3, zinc finger0.242
RNF14ring finger protein 140.238
KDM2Blysine (K)-specific demethylase 2B0.230
RAD18RAD18 homolog (S. cerevisiae)0.222
UBE2Wubiquitin-conjugating enzyme E2W (putative)0.214
TLK1tousled-like kinase 10.197
ARIH1ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)0.190
RSRC2arginine/serine-rich coiled-coil 20.187
FBXW11F-box and WD repeat domain containing 110.187
PCGF5polycomb group ring finger 50.167
SIAH1seven in absentia homolog 1 (Drosophila)0.165
RNF20ring finger protein 200.158
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.157
RNF111ring finger protein 1110.149
INO80INO80 homolog (S. cerevisiae)0.148
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.143
E2F1E2F transcription factor 10.143
ZRANB1zinc finger, RAN-binding domain containing 10.140
YAF2YY1 associated factor 20.139
CDAN1congenital dyserythropoietic anemia, type I0.139
RFWD2ring finger and WD repeat domain 20.135
UBXN1UBX domain protein 10.132
RLIMring finger protein, LIM domain interacting0.127
TOPORStopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase0.120
SCMH1sex comb on midleg homolog 1 (Drosophila)0.118
TLK2tousled-like kinase 20.111
TP53BP1tumor protein p53 binding protein 10.110
RB1retinoblastoma 10.108
FUBP1far upstream element (FUSE) binding protein 10.106
ARIH2ariadne homolog 2 (Drosophila)0.105
MDM2Mdm2 p53 binding protein homolog (mouse)0.102
CDK2cyclin-dependent kinase 20.093
RNF130ring finger protein 1300.090
RNF4ring finger protein 40.088
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.086
CUL4Bcullin 4B0.086
UBE2L3ubiquitin-conjugating enzyme E2L 30.086
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.085
CUL2cullin 20.085
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.081
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.079
RNF114ring finger protein 1140.079
NBNnibrin0.077
UBE2E3ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)0.072
TONSLtonsoku-like, DNA repair protein0.071
KIAA1712KIAA17120.069
MARCH5membrane-associated ring finger (C3HC4) 50.068
XPCxeroderma pigmentosum, complementation group C0.066
NCS1neuronal calcium sensor 10.065
CCNE1cyclin E10.060
UBR1ubiquitin protein ligase E3 component n-recognin 10.059
FBXW7F-box and WD repeat domain containing 70.057
HIST2H2AChistone cluster 2, H2ac0.056
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Rnf2ring finger protein 21.000
RybpRING1 and YY1 binding protein0.979
Pcgf2polycomb group ring finger 20.563
Cbx8chromobox homolog 8 (Drosophila Pc class)0.138
Phc2polyhomeotic-like 2 (Drosophila)0.137
Rbbp4retinoblastoma binding protein 40.096
Kdm2blysine (K)-specific demethylase 2B0.084
Csnk2a1casein kinase 2, alpha 1 polypeptide0.079
Kdm1alysine (K)-specific demethylase 1A0.071
Matr3matrin 30.069
Skp1aS-phase kinase-associated protein 1A0.067
Pcgf6polycomb group ring finger 60.052
Cdc73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.043
Cbx7chromobox homolog 70.041
MgaMAX gene associated0.040
Scaf11SR-related CTD-associated factor 110.035
Zbtb33zinc finger and BTB domain containing 330.034
Dcaf7DDB1 and CUL4 associated factor 70.031
Ezh2enhancer of zeste homolog 2 (Drosophila)0.025
Scmh1sex comb on midleg homolog 10.023
Phc3polyhomeotic-like 3 (Drosophila)0.022
Ufd1lubiquitin fusion degradation 1 like0.021
Usp7ubiquitin specific peptidase 70.021
Setdb1SET domain, bifurcated 10.020
Sos1son of sevenless homolog 1 (Drosophila)0.020
BcorBCL6 interacting corepressor0.020
Mdm2transformed mouse 3T3 cell double minute 20.019
Fyttd1forty-two-three domain containing 10.019
Mta1metastasis associated 10.019
Ighimmunoglobulin heavy chain complex0.018
Ring1ring finger protein 10.018
Phc1polyhomeotic-like 1 (Drosophila)0.018
Mdm4transformed mouse 3T3 cell double minute 40.018
Setxsenataxin0.017
Traf6TNF receptor-associated factor 60.016
Cand1cullin associated and neddylation disassociated 10.016
Yaf2YY1 associated factor 20.015
Cbx2chromobox homolog 2 (Drosophila Pc class)0.015
Hist1h2aohistone cluster 1, H2ao0.015
Hdac6histone deacetylase 60.015
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.014
Smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.014
Ezh1enhancer of zeste homolog 1 (Drosophila)0.013
Nsfl1cNSFL1 (p97) cofactor (p47)0.012
Usp9xubiquitin specific peptidase 9, X chromosome0.012
Aampangio-associated migratory protein0.012
Tfdp1transcription factor Dp 10.012
Tbl1xr1transducin (beta)-like 1X-linked receptor 10.012
Aff4AF4/FMR2 family, member 40.011
Ap1g1adaptor protein complex AP-1, gamma 1 subunit0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.010
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.010