The network for 'negative regulation of dna dependent dna replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of dna dependent dna replication

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.

NameDescriptionProbabilityFunc Analog Organism
MRC1Mrc1p0.189
DIA2Dia2p0.047
HRK1Hrk1p0.040
YPL260Whypothetical protein0.039
RAD53Rad53p0.038
PDS1Pds1p0.030
PDS5Pds5p0.025
RGC1Rgc1p0.023
YLR257Whypothetical protein0.022
TOR1Tor1p0.020
CDC39Cdc39p0.018
MCM4Mcm4p0.018
MDS3Mds3p0.018
MCM2Mcm2p0.018
SCC2Scc2p0.017
YLR177Whypothetical protein0.017
HSL1Hsl1p0.016
PAM1Pam1p0.016
PTK2Ptk2p0.015
TOF2Tof2p0.014
MCM5Mcm5p0.014
FPK1Fpk1p0.013
RMI1Rmi1p0.013
CSM3Csm3p0.013
AKL1Akl1p0.013
RAD5Rad5p0.012
FRA1Fra1p0.012
TAX4Tax4p0.012
YNL234Whypothetical protein0.012
MEC1Mec1p0.012
CTF4Ctf4p0.011
YPK1Ypk1p0.011
CMK2Cmk2p0.011
MMS1Mms1p0.011
NUR1Nur1p0.011
TGL4Tgl4p0.010
MCM3Mcm3p0.010
HAL5Hal5p0.010
RAD54Rad54p0.010
SMC6Smc6p0.010
TOF1Tof1p0.010
SAE2Sae2p0.010
UTR1Utr1p0.010
CDC34Cdc34p0.010
SFL1Sfl1p0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ucr-2.2Protein UCR-2.20.034
col-146Protein COL-1460.032
unc-27Protein UNC-270.027
col-180Protein COL-1800.026
col-43Protein COL-430.018
ZK1058.9Protein ZK1058.90.014
ifd-1Protein IFD-10.014
sfxn-5Protein SFXN-50.013
C34E7.4Protein C34E7.40.013
F35A5.1Protein F35A5.10.012
vha-12Protein VHA-120.012
mig-6Protein MIG-60.011
K10C2.1Protein K10C2.10.011
rskn-2Protein RSKN-20.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
hhhedgehog0.260
rad50CG6339 gene product from transcript CG6339-RD0.100
tefutelomere fusion0.066
panpangolin0.042
CtBPC-terminal Binding Protein0.037
esgescargot0.034
debcldeath executioner Bcl-2 homologue0.032
kniknirps0.030
cdc23CG2508 gene product from transcript CG2508-RA0.027
nbsCG6754 gene product from transcript CG6754-RC0.025
enengrailed0.024
stanstarry night0.021
gcmglial cells missing0.018
pnrpannier0.018
dikdiskette0.018
hayhaywire0.018
pxbCG33207 gene product from transcript CG33207-RB0.016
cmetCENP-meta0.016
Pk92BProtein kinase at 92B0.016
dsdachsous0.015
Rab23CG2108 gene product from transcript CG2108-RA0.015
ininturned0.015
twitwist0.014
Slip1CG1783 gene product from transcript CG1783-RA0.014
Cdk4Cyclin-dependent kinase 40.013
aseasense0.013
NotumCG13076 gene product from transcript CG13076-RB0.013
tldtolloid0.013
TfIISRNA polymerase II elongation factor0.012
unc-13CG2999 gene product from transcript CG2999-RA0.012
vgvestigial0.012
tlltailless0.012
svshaven0.012
l(3)S147910lethal (3) S1479100.012
SceSex combs extra0.012
G-ialpha65AG protein alphai subunit 65A0.012
ftfat0.012
HcfHost cell factor0.012
staustaufen0.012
kkvkrotzkopf verkehrt0.011
pimpimples0.011
bibifid0.011
CG5222CG5222 gene product from transcript CG5222-RA0.011
lunaCG33473 gene product from transcript CG33473-RB0.011
otkoff-track0.011
Taf7TBP-associated factor 70.011
nkdnaked cuticle0.010
CG4030CG4030 gene product from transcript CG4030-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RAD21RAD21 homolog (S. pombe)0.832
STAG1stromal antigen 10.567
SMC1Astructural maintenance of chromosomes 1A0.352
WAPALwings apart-like homolog (Drosophila)0.198
PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.195
NBNnibrin0.084
ATMataxia telangiectasia mutated0.036
RAD50RAD50 homolog (S. cerevisiae)0.035
CNOT2CCR4-NOT transcription complex, subunit 20.034
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.031
H2AFXH2A histone family, member X0.029
FANCD2Fanconi anemia, complementation group D20.026
PDS5APDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.022
STAG2stromal antigen 20.021
ANAPC7anaphase promoting complex subunit 70.015
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.011
ANAPC4anaphase promoting complex subunit 40.011
SMC3structural maintenance of chromosomes 30.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smc3structural maintenace of chromosomes 30.983
Smc1astructural maintenance of chromosomes 1A0.981
Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.908
Mecp2methyl CpG binding protein 20.753
Atmataxia telangiectasia mutated homolog (human)0.562
Rad21RAD21 homolog (S. pombe)0.394
Brca1breast cancer 10.391
Pds5aPDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.320
Nbnnibrin0.143
Mdm2transformed mouse 3T3 cell double minute 20.094
Trp53transformation related protein 530.063
Msh2mutS homolog 2 (E. coli)0.059
Atp11cATPase, class VI, type 11C0.043
Stag1stromal antigen 10.043
Rad50RAD50 homolog (S. cerevisiae)0.042
Pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.038
Smc6structural maintenance of chromosomes 60.035
Ireb2iron responsive element binding protein 20.035
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.034
Rfc1replication factor C (activator 1) 10.033
Smc2structural maintenance of chromosomes 20.032
CtcfCCCTC-binding factor0.031
Wdhd1WD repeat and HMG-box DNA binding protein 10.028
Scaf11SR-related CTD-associated factor 110.027
Pola1polymerase (DNA directed), alpha 10.026
Mlh1mutL homolog 1 (E. coli)0.025
Dtldenticleless homolog (Drosophila)0.025
Kitlkit ligand0.024
Pms2postmeiotic segregation increased 2 (S. cerevisiae)0.021
BlmBloom syndrome, RecQ helicase-like0.020
Mphosph9M-phase phosphoprotein 90.019
Rec8REC8 homolog (yeast)0.019
Srrm1serine/arginine repetitive matrix 10.018
Golph3lgolgi phosphoprotein 3-like0.018
Prkar1bprotein kinase, cAMP dependent regulatory, type I beta0.018
Ncapd3non-SMC condensin II complex, subunit D30.017
Emid2EMI domain containing 20.017
Slc22a17solute carrier family 22 (organic cation transporter), member 170.016
Hexim1hexamethylene bis-acetamide inducible 10.016
Suz12suppressor of zeste 12 homolog (Drosophila)0.015
Mis18bp1MIS18 binding protein 10.014
Rb1retinoblastoma 10.014
Gfra4glial cell line derived neurotrophic factor family receptor alpha 40.014
Pole2polymerase (DNA directed), epsilon 2 (p59 subunit)0.014
Trp73transformation related protein 730.014
Mycmyelocytomatosis oncogene0.013
Brd4bromodomain containing 40.013
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.013
Cbx5chromobox homolog 5 (Drosophila HP1a)0.012
Fez1fasciculation and elongation protein zeta 1 (zygin I)0.012
Prkd3protein kinase D30.012
Hoxa2homeobox A20.012
Fmr1fragile X mental retardation syndrome 1 homolog0.012
Sp1trans-acting transcription factor 10.012
Ckap5cytoskeleton associated protein 50.012
Rad21lRAD21-like (S. pombe)0.012
Mrc2mannose receptor, C type 20.011
Srbd1S1 RNA binding domain 10.011
Apbb1amyloid beta (A4) precursor protein-binding, family B, member 10.011
Mdm4transformed mouse 3T3 cell double minute 40.011
Pax7paired box gene 70.011
Srsf2serine/arginine-rich splicing factor 20.011
Ninj2ninjurin 20.011
Nenfneuron derived neurotrophic factor0.011
Hellshelicase, lymphoid specific0.011
Mms22lMMS22-like, DNA repair protein0.011
Ubtd1ubiquitin domain containing 10.011
SvopSV2 related protein0.011
Camk1gcalcium/calmodulin-dependent protein kinase I gamma0.011
Ctr9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.010
Wapalwings apart-like homolog (Drosophila)0.010
WrnWerner syndrome homolog (human)0.010
Smc1bstructural maintenance of chromosomes 1B0.010
Ankrd17ankyrin repeat domain 170.010
Kntc1kinetochore associated 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism