The network for 'negative regulation of dna binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of dna binding

Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).

NameDescriptionProbabilityFunc Analog Organism
TPK2Tpk2p0.015
MRT4Mrt4p0.014
UBI4Ubi4p0.014
UTP15Utp15p0.013
SSE2Sse2p0.012
DBP9Dbp9p0.010
UTP13Utp13p0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
shnschnurri0.020
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ZNF43zinc finger protein 430.985
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.530
FOSFBJ murine osteosarcoma viral oncogene homolog0.349
ZNF253zinc finger protein 2530.309
SKILSKI-like oncogene0.256
ZNF273zinc finger protein 2730.249
SMAD4SMAD family member 40.237
TAL1T-cell acute lymphocytic leukemia 10.176
ZNF93zinc finger protein 930.160
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.158
ZNF708zinc finger protein 7080.125
GNLYgranulysin0.117
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.116
SKIv-ski sarcoma viral oncogene homolog (avian)0.101
ZNF91zinc finger protein 910.093
SMAD9SMAD family member 90.087
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.082
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.073
ZNF675zinc finger protein 6750.072
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.063
USPL1ubiquitin specific peptidase like 10.056
YBX1Y box binding protein 10.056
ZNF680zinc finger protein 6800.051
TCF4transcription factor 40.051
ZNF117zinc finger protein 1170.047
JUNDjun D proto-oncogene0.047
ZNF254zinc finger protein 2540.044
TERF1telomeric repeat binding factor (NIMA-interacting) 10.043
NCOR2nuclear receptor corepressor 20.043
IER2immediate early response 20.042
NCOR1nuclear receptor corepressor 10.041
ZFYVE9zinc finger, FYVE domain containing 90.038
ZNF682zinc finger protein 6820.035
ZNF92zinc finger protein 920.034
NFIBnuclear factor I/B0.032
FNBP1formin binding protein 10.032
PRF1perforin 1 (pore forming protein)0.032
JUNjun proto-oncogene0.030
ZNF430zinc finger protein 4300.030
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.029
ZNF85zinc finger protein 850.028
ZNF320zinc finger protein 3200.026
CIAPIN1cytokine induced apoptosis inhibitor 10.025
EGR1early growth response 10.025
NMIN-myc (and STAT) interactor0.025
RB1retinoblastoma 10.024
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.023
ATF3activating transcription factor 30.022
STAT1signal transducer and activator of transcription 1, 91kDa0.021
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.021
ZNF107zinc finger protein 1070.020
SRSF9serine/arginine-rich splicing factor 90.020
NFIAnuclear factor I/A0.020
MSX1msh homeobox 10.019
PSEN2presenilin 2 (Alzheimer disease 4)0.019
PLSCR1phospholipid scramblase 10.019
SP1Sp1 transcription factor0.019
SENP1SUMO1/sentrin specific peptidase 10.018
CENPJcentromere protein J0.018
SOCS3suppressor of cytokine signaling 30.017
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.017
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.016
TDGthymine-DNA glycosylase0.016
ETS1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.016
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.015
CCND1cyclin D10.015
JUNBjun B proto-oncogene0.015
C10orf137chromosome 10 open reading frame 1370.015
CXXC5CXXC finger protein 50.015
SP110SP110 nuclear body protein0.014
ZNF506zinc finger protein 5060.014
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.014
OCIAD1OCIA domain containing 10.014
PIAS1protein inhibitor of activated STAT, 10.014
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.014
ZNF567zinc finger protein 5670.014
ZNF260zinc finger protein 2600.013
TBX5T-box 50.013
SYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting protein0.012
LNPEPleucyl/cystinyl aminopeptidase0.012
SOCS1suppressor of cytokine signaling 10.012
SP100SP100 nuclear antigen0.012
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.012
SAMD9sterile alpha motif domain containing 90.011
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.011
TOP1topoisomerase (DNA) I0.011
MSX2msh homeobox 20.011
KLRK1killer cell lectin-like receptor subfamily K, member 10.010
RBAKRB-associated KRAB zinc finger0.010
PRMT6protein arginine methyltransferase 60.010
ZNF100zinc finger protein 1000.010
IFI44interferon-induced protein 440.010
PFDN1prefoldin subunit 10.010
TINF2TERF1 (TRF1)-interacting nuclear factor 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)0.995
Neurod1neurogenic differentiation 10.943
Gata4GATA binding protein 40.927
Pax6paired box gene 60.898
Hand2heart and neural crest derivatives expressed transcript 20.874
Pitx2paired-like homeodomain transcription factor 20.804
Sox2SRY-box containing gene 20.757
Id3inhibitor of DNA binding 30.754
Ascl1achaete-scute complex homolog 1 (Drosophila)0.729
Neurog2neurogenin 20.706
Mstnmyostatin0.640
Tcf4transcription factor 40.623
Id1inhibitor of DNA binding 10.606
Emx2empty spiracles homolog 2 (Drosophila)0.598
Tcf3transcription factor 30.595
Emx1empty spiracles homolog 1 (Drosophila)0.549
Fgf8fibroblast growth factor 80.519
Cry2cryptochrome 2 (photolyase-like)0.508
En1engrailed 10.470
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.454
Pou4f2POU domain, class 4, transcription factor 20.383
Clockcircadian locomotor output cycles kaput0.361
Lhx3LIM homeobox protein 30.358
Pax3paired box gene 30.351
Kiss1KiSS-1 metastasis-suppressor0.336
Hand1heart and neural crest derivatives expressed transcript 10.328
Foxc1forkhead box C10.318
Neurod4neurogenic differentiation 40.312
Msx1homeobox, msh-like 10.293
Onecut1one cut domain, family member 10.286
Shhsonic hedgehog0.263
Nhlh1nescient helix loop helix 10.227
Isl1ISL1 transcription factor, LIM/homeodomain0.207
Gli2GLI-Kruppel family member GLI20.206
Tcfap2atranscription factor AP-2, alpha0.191
Gata6GATA binding protein 60.184
Ntf3neurotrophin 30.176
Foxc2forkhead box C20.152
Hes5hairy and enhancer of split 5 (Drosophila)0.129
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.124
Hey2hairy/enhancer-of-split related with YRPW motif 20.112
Madcam1mucosal vascular addressin cell adhesion molecule 10.108
Srrm4serine/arginine repetitive matrix 40.108
MecomMDS1 and EVI1 complex locus0.100
Eporerythropoietin receptor0.094
Zic2zinc finger protein of the cerebellum 20.091
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.091
Fstfollistatin0.089
Insm1insulinoma-associated 10.086
Ldb1LIM domain binding 10.079
Ptf1apancreas specific transcription factor, 1a0.077
Sox4SRY-box containing gene 40.075
Dlx2distal-less homeobox 20.075
Olig2oligodendrocyte transcription factor 20.070
Zfpm2zinc finger protein, multitype 20.069
Smad6MAD homolog 6 (Drosophila)0.068
Tefthyrotroph embryonic factor0.065
Hes1hairy and enhancer of split 1 (Drosophila)0.064
Hey1hairy/enhancer-of-split related with YRPW motif 10.064
Cdh23cadherin 23 (otocadherin)0.057
Lhx4LIM homeobox protein 40.057
Gbx2gastrulation brain homeobox 20.056
Bmpr1abone morphogenetic protein receptor, type 1A0.055
Ldb2LIM domain binding 20.055
Lhx9LIM homeobox protein 90.055
Prox1prospero-related homeobox 10.051
Gscgoosecoid homeobox0.050
Pou4f3POU domain, class 4, transcription factor 30.048
Zic1zinc finger protein of the cerebellum 10.048
Neurog3neurogenin 30.047
Pou3f2POU domain, class 3, transcription factor 20.046
Ush1gUsher syndrome 1G homolog (human)0.045
Tbx3T-box 30.044
Per2period homolog 2 (Drosophila)0.044
Usp2ubiquitin specific peptidase 20.043
Csnk1ecasein kinase 1, epsilon0.043
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.042
Mab21l2mab-21-like 2 (C. elegans)0.040
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.040
Mesp1mesoderm posterior 10.040
Socs1suppressor of cytokine signaling 10.039
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.039
Gli3GLI-Kruppel family member GLI30.038
Sox11SRY-box containing gene 110.038
Wfikkn1WAP, FS, Ig, KU, and NTR-containing protein 10.038
Hoxd13homeobox D130.037
Snai1snail homolog 1 (Drosophila)0.037
Gpr50G-protein-coupled receptor 500.036
Isl2insulin related protein 2 (islet 2)0.036
Zic3zinc finger protein of the cerebellum 30.035
Tbx20T-box 200.034
Lef1lymphoid enhancer binding factor 10.033
Sqstm1sequestosome 10.033
Gas1growth arrest specific 10.033
Gdf11growth differentiation factor 110.033
Rspo2R-spondin 2 homolog (Xenopus laevis)0.032
Inca1inhibitor of CDK, cyclin A1 interacting protein 10.032
Epha3Eph receptor A30.032
UncxUNC homeobox0.032
Pitx1paired-like homeodomain transcription factor 10.031
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism