The network for 'positive regulation of epidermal growth factor activated receptor activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of epidermal growth factor activated receptor activity

Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG1677CG1677 gene product from transcript CG1677-RB0.051
CG2807CG2807 gene product from transcript CG2807-RA0.037
Aos1CG12276 gene product from transcript CG12276-RA0.031
Kap-alpha1karyopherin alpha10.030
Rad23CG1836 gene product from transcript CG1836-RB0.027
CG1344CG1344 gene product from transcript CG1344-RA0.025
CG7028CG7028 gene product from transcript CG7028-RA0.024
CG5602CG5602 gene product from transcript CG5602-RA0.022
Fcp1CG12252 gene product from transcript CG12252-RA0.021
DekCG5935 gene product from transcript CG5935-RA0.021
CG3605CG3605 gene product from transcript CG3605-RA0.018
l(2)NC136lethal (2) NC1360.018
CG18292CG18292 gene product from transcript CG18292-RA0.018
emcextra macrochaetae0.017
CG6686CG6686 gene product from transcript CG6686-RB0.017
Rpb5CG11979 gene product from transcript CG11979-RA0.017
RpA-70Replication Protein A 700.016
CG12391CG12391 gene product from transcript CG12391-RA0.016
CG11107CG11107 gene product from transcript CG11107-RA0.016
Cp190Centrosomal protein 190kD0.015
eIF5CG9177 gene product from transcript CG9177-RE0.015
CG8878CG8878 gene product from transcript CG8878-RA0.015
MED22Mediator complex subunit 220.015
CG14749CG14749 gene product from transcript CG14749-RA0.015
Rat1CG10354 gene product from transcript CG10354-RA0.015
CG2199CG2199 gene product from transcript CG2199-RB0.015
D1D1 chromosomal protein0.014
CG9915CG9915 gene product from transcript CG9915-RB0.014
CG8924CG8924 gene product from transcript CG8924-RB0.013
CG4266CG4266 gene product from transcript CG4266-RA0.013
l(2)03709lethal (2) 037090.013
CG2021CG2021 gene product from transcript CG2021-RA0.013
mit(1)15mitotic 150.013
NELF-ACG5874 gene product from transcript CG5874-RA0.012
CG7197CG7197 gene product from transcript CG7197-RA0.012
Caf1Chromatin assembly factor 1 subunit0.012
Aats-ileIsoleucyl-tRNA synthetase0.012
Dip2Dorsal interacting protein 20.012
SetCG4299 gene product from transcript CG4299-RA0.011
gammaTub23Cgamma-Tubulin at 23C0.011
CG7185CG7185 gene product from transcript CG7185-RA0.011
TfIIFbetaTranscription factor TFIIFbeta0.011
CG6610CG6610 gene product from transcript CG6610-RA0.011
SfmbtScm-related gene containing four mbt domains0.010
CG8928CG8928 gene product from transcript CG8928-RA0.010
Nopp140CG7421 gene product from transcript CG7421-RB0.010
Art1Arginine methyltransferase 10.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ABI2abl-interactor 20.421
MPDZmultiple PDZ domain protein0.379
SNX33sorting nexin 330.325
SNX9sorting nexin 90.300
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.292
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.225
EGFRepidermal growth factor receptor0.158
DLG1discs, large homolog 1 (Drosophila)0.084
SH3PXD2ASH3 and PX domains 2A0.069
PACSIN3protein kinase C and casein kinase substrate in neurons 30.054
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.053
PTPN1protein tyrosine phosphatase, non-receptor type 10.044
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.032
SH3D19SH3 domain containing 190.031
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.028
CCDC6coiled-coil domain containing 60.027
PDCD6IPprogrammed cell death 6 interacting protein0.026
MUC1mucin 1, cell surface associated0.025
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.023
ADAM15ADAM metallopeptidase domain 150.022
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.021
DKK1dickkopf homolog 1 (Xenopus laevis)0.021
FASLGFas ligand (TNF superfamily, member 6)0.021
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.021
SPRR2Asmall proline-rich protein 2A0.021
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.018
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.017
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.016
CCNE1cyclin E10.015
MMP14matrix metallopeptidase 14 (membrane-inserted)0.015
IGFBP3insulin-like growth factor binding protein 30.015
CAPRIN2caprin family member 20.014
FBXW2F-box and WD repeat domain containing 20.013
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.013
PTPRAprotein tyrosine phosphatase, receptor type, A0.012
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.011
GRB10growth factor receptor-bound protein 100.011
NOS1APnitric oxide synthase 1 (neuronal) adaptor protein0.011
PTK2PTK2 protein tyrosine kinase 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Egfrepidermal growth factor receptor0.962
Cpeb3cytoplasmic polyadenylation element binding protein 30.728
Klf3Kruppel-like factor 3 (basic)0.713
Foxc1forkhead box C10.539
Il6stinterleukin 6 signal transducer0.489
Tgfatransforming growth factor alpha0.409
Cd44CD44 antigen0.271
Nr3c1nuclear receptor subfamily 3, group C, member 10.245
Hif1ahypoxia inducible factor 1, alpha subunit0.237
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.210
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.186
Ctnnb1catenin (cadherin associated protein), beta 10.167
Ptenphosphatase and tensin homolog0.139
Gsdma3gasdermin A30.111
Cenpjcentromere protein J0.092
Smad3MAD homolog 3 (Drosophila)0.090
Sos1son of sevenless homolog 1 (Drosophila)0.087
Trp53transformation related protein 530.086
Ptpn11protein tyrosine phosphatase, non-receptor type 110.079
Tgfb2transforming growth factor, beta 20.077
Vegfavascular endothelial growth factor A0.067
Efnb2ephrin B20.057
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.054
Gja1gap junction protein, alpha 10.053
Lyz2lysozyme 20.047
Camk2bcalcium/calmodulin-dependent protein kinase II, beta0.041
Epn2epsin 20.035
Hrkharakiri, BCL2 interacting protein (contains only BH3 domain)0.035
Igf2insulin-like growth factor 20.034
Egfepidermal growth factor0.034
CblCasitas B-lineage lymphoma0.034
Wnt7bwingless-related MMTV integration site 7B0.030
Mdm2transformed mouse 3T3 cell double minute 20.030
Tgfbr1transforming growth factor, beta receptor I0.029
Apcadenomatosis polyposis coli0.029
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.027
Vhlvon Hippel-Lindau tumor suppressor0.026
Klk6kallikrein related-peptidase 60.025
Jag1jagged 10.025
Hbegfheparin-binding EGF-like growth factor0.024
Mchr1melanin-concentrating hormone receptor 10.023
Epas1endothelial PAS domain protein 10.023
Pitx2paired-like homeodomain transcription factor 20.023
Kcnd1potassium voltage-gated channel, Shal-related family, member 10.022
Cacng2calcium channel, voltage-dependent, gamma subunit 20.021
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.021
Cxcr7chemokine (C-X-C motif) receptor 70.021
BrafBraf transforming gene0.021
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.020
Kcnc4potassium voltage gated channel, Shaw-related subfamily, member 40.020
Magi3membrane associated guanylate kinase, WW and PDZ domain containing 30.020
Btcbetacellulin, epidermal growth factor family member0.020
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.019
Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 20.019
Itgb1integrin beta 1 (fibronectin receptor beta)0.017
Vstm2bV-set and transmembrane domain containing 2B0.017
Apoeapolipoprotein E0.017
Nos3nitric oxide synthase 3, endothelial cell0.017
Foxn4forkhead box N40.017
Gata4GATA binding protein 40.016
Cbscystathionine beta-synthase0.016
Lhx6LIM homeobox protein 60.016
Bmpr1abone morphogenetic protein receptor, type 1A0.016
Prl8a9prolactin family8, subfamily a, member 90.015
Nptx1neuronal pentraxin 10.015
Yipf7Yip1 domain family, member 70.015
Lystlysosomal trafficking regulator0.014
Prkceprotein kinase C, epsilon0.014
Rxraretinoid X receptor alpha0.014
Ly6hlymphocyte antigen 6 complex, locus H0.013
6330408A02RikRIKEN cDNA 6330408A02 gene0.013
D730048I06RikRIKEN cDNA D730048I06 gene0.013
Pax6paired box gene 60.013
Kif1akinesin family member 1A0.013
Rps6ka3ribosomal protein S6 kinase polypeptide 30.013
Slc30a3solute carrier family 30 (zinc transporter), member 30.013
Hoxa10homeobox A100.012
Htr3b5-hydroxytryptamine (serotonin) receptor 3B0.012
Ptpn14protein tyrosine phosphatase, non-receptor type 140.012
Acbd3acyl-Coenzyme A binding domain containing 30.012
Arnt2aryl hydrocarbon receptor nuclear translocator 20.012
Adcy9adenylate cyclase 90.012
Cdh6cadherin 60.012
Sez6lseizure related 6 homolog like0.012
Fzd9frizzled homolog 9 (Drosophila)0.012
Jph3junctophilin 30.011
Adam17a disintegrin and metallopeptidase domain 170.011
Olfr140olfactory receptor 1400.011
Rhbdl1rhomboid, veinlet-like 1 (Drosophila)0.011
Tas2r105taste receptor, type 2, member 1050.011
Mapk9mitogen-activated protein kinase 90.011
Gsk3bglycogen synthase kinase 3 beta0.011
Mapk8mitogen-activated protein kinase 80.011
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.011
Arid1aAT rich interactive domain 1A (SWI-like)0.011
Fgfr2fibroblast growth factor receptor 20.011
Foxa3forkhead box A30.011
P4ha1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cx3cr1chemokine (C-X3-C motif) receptor 10.027
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.011
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.010