The network for 'regulation of g2 m transition of mitotic cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of g2 m transition of mitotic cell cycle

Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.

NameDescriptionProbabilityFunc Analog Organism
RAD53Rad53p0.579
KEL1Kel1p0.351
ZDS1Zds1p0.348
PDS1Pds1p0.127
DPB2Dpb2p0.121
KCC4Kcc4p0.101
BEM3Bem3p0.055
DPB11Dpb11p0.049
CDC3Cdc3p0.049
IML1Iml1p0.047
CDC55Cdc55p0.041
PKC1Pkc1p0.040
HSL1Hsl1p0.039
TEL1Tel1p0.036
MRC1Mrc1p0.034
IST1Ist1p0.031
SRD1Srd1p0.027
LEU2Leu2p0.023
YOL038C-Ahypothetical protein0.023
YLR162Whypothetical protein0.022
SPR6Spr6p0.022
KIN2Kin2p0.022
YLR264C-Ahypothetical protein0.020
ARP10Arp10p0.020
ADH2Adh2p0.020
MER1Mer1p0.019
BNR1Bnr1p0.019
CRP1Crp1p0.018
PPH22Pph22p0.017
ECM25Ecm25p0.017
SPL2Spl2p0.016
DUN1Dun1p0.016
SLK19Slk19p0.016
YAR068Whypothetical protein0.016
YML053Chypothetical protein0.015
NIS1Nis1p0.015
YNL234Whypothetical protein0.015
YBR013Chypothetical protein0.015
ARG8Arg8p0.015
TIF4632Tif4632p0.014
OPT2Opt2p0.014
ATP6Atp6p0.014
SMC4Smc4p0.014
MCM4Mcm4p0.014
ZDS2Zds2p0.014
RTS1Rts1p0.014
CUP1-1Cup1-1p0.013
CPD1Cpd1p0.013
ZPS1Zps1p0.013
YIR035Chypothetical protein0.013
YPR157Whypothetical protein0.013
YLR042Chypothetical protein0.013
STT4Stt4p0.013
FMT1Fmt1p0.013
YPL014Whypothetical protein0.012
YIL151Chypothetical protein0.012
HPF1Hpf1p0.012
BSC1Bsc1p0.012
HXT3Hxt3p0.012
AUA1Aua1p0.012
RAD55Rad55p0.012
GYL1Gyl1p0.012
YPR174Chypothetical protein0.011
YKR075Chypothetical protein0.011
TYE7Tye7p0.011
PRI1Pri1p0.011
IZH4Izh4p0.011
YOL013W-Ahypothetical protein0.011
MF(ALPHA)2Mf(alpha)2p0.011
PRI2Pri2p0.011
CAR1Car1p0.011
SWE1Swe1p0.011
BOI1Boi1p0.011
DIC1Dic1p0.010
ESP1Esp1p0.010
ALT2Alt2p0.010
CLA4Cla4p0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ess-2Protein ESS-20.016
hlh-30Protein HLH-300.015
cam-1Protein CAM-10.014
C05C10.2Protein C05C10.20.012
mcm-7Protein MCM-70.011
CELE_W05H9.2Protein W05H9.20.011
lin-9Protein LIN-90.011
set-5Protein SET-50.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ykiyorkie0.049
hydhyperplastic discs0.049
cnncentrosomin0.045
DNApol-alpha60DNA polymerase alpha 60kD0.038
BubR1Bub1-related kinase0.034
aspabnormal spindle0.030
MCPH1Microcephalin0.028
CycDCyclin D0.026
skdskuld0.025
dupdouble parked0.022
l(3)mbtlethal (3) malignant brain tumor0.021
mei-9meiotic 90.020
CycGCyclin G0.019
spn-Bspindle B0.019
nejnejire0.018
CG9772CG9772 gene product from transcript CG9772-RB0.018
toctoucan0.017
Su(H)Suppressor of Hairless0.016
Tip60CG6121 gene product from transcript CG6121-RA0.014
lokloki0.014
p53CG33336 gene product from transcript CG33336-RB0.014
tefutelomere fusion0.013
dre4CG1828 gene product from transcript CG1828-RB0.013
mus309mutagen-sensitive 3090.013
CG14962CG14962 gene product from transcript CG14962-RA0.012
CycJCyclin J0.012
piepineapple eye0.012
cmetCENP-meta0.011
flowerCG6151 gene product from transcript CG6151-RA0.011
wispwispy0.011
luteCG5319 gene product from transcript CG5319-RA0.011
CycECyclin E0.011
liglingerer0.011
dapdacapo0.011
4EHPCG33100 gene product from transcript CG33100-RA0.011
CG5794CG5794 gene product from transcript CG5794-RB0.010
Sgt1CG9617 gene product from transcript CG9617-RA0.010
CG2371CG2371 gene product from transcript CG2371-RB0.010
pygopygopus0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.955
CDK6cyclin-dependent kinase 60.898
RB1retinoblastoma 10.871
CCND1cyclin D10.865
BRCA1breast cancer 1, early onset0.820
CCT4chaperonin containing TCP1, subunit 4 (delta)0.807
CCND3cyclin D30.797
RAD51L3RAD51-like 3 (S. cerevisiae)0.503
CCT8chaperonin containing TCP1, subunit 8 (theta)0.474
CDK2cyclin-dependent kinase 20.453
HDAC1histone deacetylase 10.407
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.389
C19orf39chromosome 19 open reading frame 390.342
BLMBloom syndrome, RecQ helicase-like0.305
RAD51L1RAD51-like 1 (S. cerevisiae)0.269
PTPN23protein tyrosine phosphatase, non-receptor type 230.260
RBL1retinoblastoma-like 1 (p107)0.235
CDC45cell division cycle 45 homolog (S. cerevisiae)0.232
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.232
LIN9lin-9 homolog (C. elegans)0.194
CDK9cyclin-dependent kinase 90.182
CDK4cyclin-dependent kinase 40.144
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.133
CCNE1cyclin E10.123
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.119
MEIS1Meis homeobox 10.104
TCP1t-complex 10.103
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.101
TIMELESStimeless homolog (Drosophila)0.099
PDE4DIPphosphodiesterase 4D interacting protein0.096
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.096
MCM10minichromosome maintenance complex component 100.088
NR2E3nuclear receptor subfamily 2, group E, member 30.088
MEIS2Meis homeobox 20.085
CLSPNclaspin0.081
CDKN2Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.079
CUL1cullin 10.073
UHRF2ubiquitin-like with PHD and ring finger domains 20.061
XRCC2X-ray repair complementing defective repair in Chinese hamster cells 20.061
RBBP7retinoblastoma binding protein 70.059
CCNT1cyclin T10.057
SKA2spindle and kinetochore associated complex subunit 20.051
MTA2metastasis associated 1 family, member 20.050
E2F4E2F transcription factor 4, p107/p130-binding0.046
XRCC3X-ray repair complementing defective repair in Chinese hamster cells 30.045
CCND2cyclin D20.044
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.042
CUL2cullin 20.041
CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.041
CDC25Acell division cycle 25 homolog A (S. pombe)0.037
MTA1metastasis associated 10.036
CHMP1Achromatin modifying protein 1A0.034
RAD51CRAD51 homolog C (S. cerevisiae)0.033
ATRIPATR interacting protein0.030
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.030
MDM2Mdm2 p53 binding protein homolog (mouse)0.030
AKAP12A kinase (PRKA) anchor protein 120.029
KRTAP4-12keratin associated protein 4-120.028
SKP1S-phase kinase-associated protein 10.027
CDC7cell division cycle 7 homolog (S. cerevisiae)0.025
LIN54lin-54 homolog (C. elegans)0.025
CDKN2Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.024
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.023
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.022
CDC25Ccell division cycle 25 homolog C (S. pombe)0.021
TTI1Tel2 interacting protein 1 homolog (S. pombe)0.021
E2F1E2F transcription factor 10.021
BTRCbeta-transducin repeat containing0.021
CDK11Bcyclin-dependent kinase 11B0.021
TOPBP1topoisomerase (DNA) II binding protein 10.021
RAD50RAD50 homolog (S. cerevisiae)0.021
NUP133nucleoporin 133kDa0.021
HIPK2homeodomain interacting protein kinase 20.020
SMC1Astructural maintenance of chromosomes 1A0.019
RAD9ARAD9 homolog A (S. pombe)0.019
SKP2S-phase kinase-associated protein 2 (p45)0.019
CDK14cyclin-dependent kinase 140.019
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.018
RUNX1runt-related transcription factor 10.018
DEAF1deformed epidermal autoregulatory factor 1 (Drosophila)0.017
H1F0H1 histone family, member 00.017
FYNFYN oncogene related to SRC, FGR, YES0.017
SKA3spindle and kinetochore associated complex subunit 30.016
PCGF2polycomb group ring finger 20.016
USP8ubiquitin specific peptidase 80.015
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.015
ATMINATM interactor0.015
TCEB2transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)0.015
CHAF1Achromatin assembly factor 1, subunit A (p150)0.014
CHD4chromodomain helicase DNA binding protein 40.014
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.014
DBN1drebrin 10.014
SERTAD4SERTA domain containing 40.014
MAF1MAF1 homolog (S. cerevisiae)0.014
BRIP1BRCA1 interacting protein C-terminal helicase 10.014
PPME1protein phosphatase methylesterase 10.013
MDC1mediator of DNA-damage checkpoint 10.013
BRCA2breast cancer 2, early onset0.013
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.013
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.013
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Brca1breast cancer 10.398
Brca2breast cancer 20.371
Prnpprion protein0.371
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.215
Tcfcp2l1transcription factor CP2-like 10.134
Ccnd1cyclin D10.129
Cdk4cyclin-dependent kinase 40.091
Trp53transformation related protein 530.083
Cdc25ccell division cycle 25 homolog C (S. pombe)0.071
Hdac1histone deacetylase 10.059
Ctnnb1catenin (cadherin associated protein), beta 10.048
Hoxa2homeobox A20.043
Wnt3awingless-related MMTV integration site 3A0.033
Arid1aAT rich interactive domain 1A (SWI-like)0.032
Timelesstimeless homolog (Drosophila)0.031
Suds3suppressor of defective silencing 3 homolog (S. cerevisiae)0.030
Mta1metastasis associated 10.029
Lig1ligase I, DNA, ATP-dependent0.028
Lhx1LIM homeobox protein 10.028
E2f1E2F transcription factor 10.026
Meis2Meis homeobox 20.024
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.023
Rbl1retinoblastoma-like 1 (p107)0.023
Amhr2anti-Mullerian hormone type 2 receptor0.022
Meis1Meis homeobox 10.022
Mta2metastasis-associated gene family, member 20.021
Sin3atranscriptional regulator, SIN3A (yeast)0.020
Porcnporcupine homolog (Drosophila)0.020
Wnt10bwingless related MMTV integration site 10b0.019
Cdkn1bcyclin-dependent kinase inhibitor 1B0.019
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.019
Tbrachyury0.019
Trp73transformation related protein 730.019
Trim28tripartite motif-containing 280.019
Cdk6cyclin-dependent kinase 60.018
Emx1empty spiracles homolog 1 (Drosophila)0.018
Chd4chromodomain helicase DNA binding protein 40.018
Cdt1chromatin licensing and DNA replication factor 10.017
Ror2receptor tyrosine kinase-like orphan receptor 20.017
Ccnd2cyclin D20.017
Dtldenticleless homolog (Drosophila)0.017
Clstn1calsyntenin 10.017
Appamyloid beta (A4) precursor protein0.016
E130303B06RikRIKEN cDNA E130303B06 gene0.016
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.016
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.016
Dkk1dickkopf homolog 1 (Xenopus laevis)0.015
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.015
Wdhd1WD repeat and HMG-box DNA binding protein 10.014
Hoxa9homeobox A90.014
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.013
Fgf18fibroblast growth factor 180.013
Sh3gl3SH3-domain GRB2-like 30.012
Gata1GATA binding protein 10.012
Wnt4wingless-related MMTV integration site 40.012
Mbd3methyl-CpG binding domain protein 30.012
Rad51ap1RAD51 associated protein 10.012
Rarbretinoic acid receptor, beta0.012
Bmp7bone morphogenetic protein 70.012
Cdk2cyclin-dependent kinase 20.011
Fgf8fibroblast growth factor 80.011
Tmeff2transmembrane protein with EGF-like and two follistatin-like domains 20.011
Cdca2cell division cycle associated 20.011
PaskPAS domain containing serine/threonine kinase0.011
Wnt6wingless-related MMTV integration site 60.011
Hcfc1host cell factor C10.011
Msh2mutS homolog 2 (E. coli)0.010
Retret proto-oncogene0.010
Mms22lMMS22-like, DNA repair protein0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hk1hexokinase 10.118
Nedd4neural precursor cell expressed, developmentally down-regulated 40.090
Rab1bRAB1B, member RAS oncogene family0.064
Jak1Janus kinase 10.056
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.048
Usf2upstream transcription factor 2, c-fos interacting0.046
Ccnd3cyclin D30.037
Ubtfupstream binding transcription factor, RNA polymerase I0.035
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.034
Fgfr1Fibroblast growth factor receptor 10.033
Eef2eukaryotic translation elongation factor 20.030
Mpripmyosin phosphatase Rho interacting protein0.030
Git1G protein-coupled receptor kinase interacting ArfGAP 10.028
Vcpvalosin-containing protein0.028
Tolliptoll interacting protein0.027
Ralgdsral guanine nucleotide dissociation stimulator0.025
Mcm6minichromosome maintenance complex component 60.024
Top2atopoisomerase (DNA) II alpha0.023
Pparaperoxisome proliferator activated receptor alpha0.022
Psme4proteasome (prosome, macropain) activator subunit 40.021
Cyfip2cytoplasmic FMR1 interacting protein 20.021
Gja1gap junction protein, alpha 10.021
Usp15ubiquitin specific peptidase 150.020
Glg1golgi apparatus protein 10.020
Gna12guanine nucleotide binding protein (G protein) alpha 120.020
Sbk1SH3-binding domain kinase 10.019
Myo9amyosin IXA0.019
Gas7growth arrest specific 70.018
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.018
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.018
Psapprosaposin0.017
Camk2dcalcium/calmodulin-dependent protein kinase II delta0.017
Usp9xubiquitin specific peptidase 9, X-linked0.017
Csnk1g2casein kinase 1, gamma 20.017
Rab11bRAB11B, member RAS oncogene family0.017
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.017
Homer1homer homolog 1 (Drosophila)0.016
Sptan1spectrin, alpha, non-erythrocytic 10.016
Neflneurofilament, light polypeptide0.016
Rps6kb1ribosomal protein S6 kinase, polypeptide 10.016
Kif5bkinesin family member 5B0.016
Myh10myosin, heavy chain 10, non-muscle0.015
Fhl1four and a half LIM domains 10.015
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.015
Cdt1chromatin licensing and DNA replication factor 10.015
Hist1h1ahistone cluster 1, H1a0.014
Gap43growth associated protein 430.014
Stat6signal transducer and activator of transcription 60.014
Smad4SMAD family member 40.014
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.014
GeftRhoA/RAC/CDC42 exchange factor0.014
Myo1cmyosin IC0.014
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.014
Gpr37G protein-coupled receptor 370.013
Sirpasignal-regulatory protein alpha0.013
Plcb1phospholipase C, beta 1 (phosphoinositide-specific)0.013
Grm7glutamate receptor, metabotropic 70.013
Stxbp1syntaxin binding protein 10.013
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.013
Dlg3discs, large homolog 3 (Drosophila)0.013
Pgrprogesterone receptor0.012
RGD1559896similar to RIKEN cDNA 2310022B050.012
Plp1proteolipid protein 10.012
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.012
Taok1TAO kinase 10.012
Prccpapillary renal cell carcinoma (translocation-associated)0.012
Gins1GINS complex subunit 1 (Psf1 homolog)0.012
Itpr1inositol 1,4,5-triphosphate receptor, type 10.012
Nexnnexilin (F actin binding protein)0.012
Xpo7exportin 70.012
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.012
Rassf5Ras association (RalGDS/AF-6) domain family member 50.012
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.012
Ptgfrnprostaglandin F2 receptor negative regulator0.011
Dnajc14DnaJ (Hsp40) homolog, subfamily C, member 140.011
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.011
Nrd1nardilysin 10.011
Cacnb3calcium channel, voltage-dependent, beta 3 subunit0.011
Sfrs12splicing factor, arginine/serine-rich 120.011
AktipAKT interacting protein0.011
Rykreceptor-like tyrosine kinase0.011
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.011
Ptprsprotein tyrosine phosphatase, receptor type, S0.011
Arhgap1Rho GTPase activating protein 10.011
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.011
Pygmphosphorylase, glycogen, muscle0.011
Dlgap1discs, large (Drosophila) homolog-associated protein 10.011
Gins4GINS complex subunit 4 (Sld5 homolog)0.011
Phlpp1PH domain and leucine rich repeat protein phosphatase 10.011
Zc3h7bzinc finger CCCH-type containing 7B0.011
Dazap2DAZ associated protein 20.010
H1f0H1 histone family, member 00.010
Dhfrdihydrofolate reductase0.010
Wdr26WD repeat domain 260.010
Grinl1aglutamate receptor, ionotropic, N-methyl D-aspartate-like 1A0.010
Oaz2ornithine decarboxylase antizyme 20.010
Acin1apoptotic chromatin condensation inducer 10.010
Dclk1doublecortin-like kinase 10.010
Fat1FAT tumor suppressor homolog 1 (Drosophila)0.010
RGD1309922similar to 2610301G19Rik protein0.010