The network for 'regulation of transcription initiation from rna polymerase ii promoter' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription initiation from rna polymerase ii promoter

Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.

NameDescriptionProbabilityFunc Analog Organism
SPT16Spt16p0.984
SPT5Spt5p0.868
RPT6Rpt6p0.409
TAF5Taf5p0.408
TAF6Taf6p0.381
RPT2Rpt2p0.365
RPN1Rpn1p0.362
TAF12Taf12p0.335
CTR9Ctr9p0.299
CHD1Chd1p0.292
TAF10Taf10p0.276
RTF1Rtf1p0.275
RPT5Rpt5p0.241
NGG1Ngg1p0.234
RPN2Rpn2p0.193
SPT6Spt6p0.187
LEO1Leo1p0.174
TFG1Tfg1p0.174
MOT1Mot1p0.172
RSC4Rsc4p0.163
SPT8Spt8p0.145
RPT1Rpt1p0.139
SUS1Sus1p0.131
TRA1Tra1p0.120
TFG2Tfg2p0.120
SEM1Sem1p0.119
SET2Set2p0.101
TAF4Taf4p0.097
RPN9Rpn9p0.094
RPN6Rpn6p0.091
RAD23Rad23p0.084
TAF8Taf8p0.079
ADA2Ada2p0.076
RPN7Rpn7p0.065
SKI3Ski3p0.061
RPT4Rpt4p0.059
TIF4632Tif4632p0.058
RPT3Rpt3p0.052
SPT7Spt7p0.050
HDA2Hda2p0.048
INO80Ino80p0.043
SPN1Spn1p0.042
TAF7Taf7p0.039
RPN3Rpn3p0.038
ISW1Isw1p0.038
HHT1Hht1p0.038
RPO21Rpo21p0.037
TFA1Tfa1p0.037
BUR6Bur6p0.036
SRD1Srd1p0.036
SWI1Swi1p0.035
RSC8Rsc8p0.034
TAF9Taf9p0.034
WWM1Wwm1p0.034
RPN13Rpn13p0.033
CKA1Cka1p0.033
YLR264C-Ahypothetical protein0.033
LEU2Leu2p0.031
POB3Pob3p0.031
YLR162Whypothetical protein0.030
YIL151Chypothetical protein0.029
REB1Reb1p0.029
YOL038C-Ahypothetical protein0.028
HXT3Hxt3p0.028
STH1Sth1p0.027
ARG8Arg8p0.027
MER1Mer1p0.026
SPT20Spt20p0.026
DLS1Dls1p0.026
IOC4Ioc4p0.026
TAE2Tae2p0.026
ARP10Arp10p0.026
YPR157Whypothetical protein0.025
RPN10Rpn10p0.024
URA3Ura3p0.024
YGR017Whypothetical protein0.024
HOHop0.024
ECM29Ecm29p0.024
YAR068Whypothetical protein0.024
CHA1Cha1p0.024
PRS2Prs2p0.023
YLR042Chypothetical protein0.023
ATP6Atp6p0.023
HPF1Hpf1p0.022
CUP1-1Cup1-1p0.022
SPL2Spl2p0.022
IOC2Ioc2p0.022
SWC7Swc7p0.022
NUP49Nup49p0.021
UFO1Ufo1p0.021
AUA1Aua1p0.021
AQY2Aqy2p0.021
TAF3Taf3p0.021
FMT1Fmt1p0.020
YBR013Chypothetical protein0.020
SCM4Scm4p0.020
YOL013W-Ahypothetical protein0.020
ADH2Adh2p0.020
SUA7Sua7p0.020
SCD6Scd6p0.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.553
TBPTATA box binding protein0.519
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.474
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.449
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.376
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.368
SMAD4SMAD family member 40.337
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.276
RXRAretinoid X receptor, alpha0.205
NCOA6nuclear receptor coactivator 60.183
SKILSKI-like oncogene0.123
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.118
NCOR2nuclear receptor corepressor 20.113
SP1Sp1 transcription factor0.100
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.099
TBX5T-box 50.098
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.087
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.084
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.081
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.070
NCOR1nuclear receptor corepressor 10.053
DCP1BDCP1 decapping enzyme homolog B (S. cerevisiae)0.053
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.052
NCOA1nuclear receptor coactivator 10.050
TAF1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa0.049
HMGB2high mobility group box 20.049
MED25mediator complex subunit 250.047
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.047
SSRP1structure specific recognition protein 10.047
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.045
PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.041
SUZ12suppressor of zeste 12 homolog (Drosophila)0.035
ARNTaryl hydrocarbon receptor nuclear translocator0.035
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.033
KAT2BK(lysine) acetyltransferase 2B0.032
PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 90.027
SMAD2SMAD family member 20.026
SMAD9SMAD family member 90.024
TRIM33tripartite motif containing 330.023
CREBBPCREB binding protein0.023
HMGA1high mobility group AT-hook 10.021
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.021
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.021
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.020
SIRT1sirtuin 10.020
EP300E1A binding protein p3000.019
PPARAperoxisome proliferator-activated receptor alpha0.019
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.019
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa0.019
TAF1CTATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa0.017
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.017
NCOA3nuclear receptor coactivator 30.016
NBNnibrin0.015
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.015
RB1retinoblastoma 10.015
MKL1megakaryoblastic leukemia (translocation) 10.014
THUMPD1THUMP domain containing 10.014
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.013
WAPALwings apart-like homolog (Drosophila)0.013
HDGFhepatoma-derived growth factor0.013
ARandrogen receptor0.012
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.012
TP53BP1tumor protein p53 binding protein 10.012
MED1mediator complex subunit 10.011
KLHL24kelch-like 24 (Drosophila)0.011
SMAD3SMAD family member 30.011
MDC1mediator of DNA-damage checkpoint 10.011
HMGB1high mobility group box 10.011
HNF4Ahepatocyte nuclear factor 4, alpha0.011
E2F1E2F transcription factor 10.011
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.010
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.010
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgf8fibroblast growth factor 80.862
Shhsonic hedgehog0.685
Sox9SRY-box containing gene 90.479
Gli2GLI-Kruppel family member GLI20.441
Fgfr2fibroblast growth factor receptor 20.349
Gli3GLI-Kruppel family member GLI30.275
Pax2paired box gene 20.239
Pax8paired box gene 80.230
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.198
Hand1heart and neural crest derivatives expressed transcript 10.171
Foxc1forkhead box C10.119
Gata4GATA binding protein 40.114
Ctnnb1catenin (cadherin associated protein), beta 10.082
Hand2heart and neural crest derivatives expressed transcript 20.080
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.079
Rarbretinoic acid receptor, beta0.078
Trp53transformation related protein 530.064
Vax1ventral anterior homeobox containing gene 10.062
Trp63transformation related protein 630.059
Stat2signal transducer and activator of transcription 20.052
Lhx1LIM homeobox protein 10.050
Tbx1T-box 10.047
Hmx3H6 homeobox 30.045
Rxraretinoid X receptor alpha0.045
Ror2receptor tyrosine kinase-like orphan receptor 20.044
Ptpn11protein tyrosine phosphatase, non-receptor type 110.042
Hoxd11homeobox D110.041
Nkx6-1NK6 homeobox 10.040
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.040
Bmp7bone morphogenetic protein 70.039
Nognoggin0.038
Fgfr1fibroblast growth factor receptor 10.033
Dkk1dickkopf homolog 1 (Xenopus laevis)0.033
Ptch1patched homolog 10.033
Ntf3neurotrophin 30.032
Efnb2ephrin B20.032
Foxa2forkhead box A20.031
Rargretinoic acid receptor, gamma0.031
Hoxa13homeobox A130.031
Hoxd13homeobox D130.030
Tgfb2transforming growth factor, beta 20.030
Pthlhparathyroid hormone-like peptide0.029
Gdnfglial cell line derived neurotrophic factor0.029
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.027
Wnt6wingless-related MMTV integration site 60.027
Wnt3awingless-related MMTV integration site 3A0.027
Twist2twist homolog 2 (Drosophila)0.026
Lhx3LIM homeobox protein 30.026
Rararetinoic acid receptor, alpha0.026
Cdkn1bcyclin-dependent kinase inhibitor 1B0.025
Stat3signal transducer and activator of transcription 30.025
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.025
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.024
Pax1paired box gene 10.024
Foxc2forkhead box C20.023
Pitx1paired-like homeodomain transcription factor 10.023
Pitx2paired-like homeodomain transcription factor 20.023
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.023
Esr1estrogen receptor 1 (alpha)0.023
Msx1homeobox, msh-like 10.022
Arandrogen receptor0.021
Zeb1zinc finger E-box binding homeobox 10.021
Ikzf1IKAROS family zinc finger 10.021
Socs1suppressor of cytokine signaling 10.021
Fgfr3fibroblast growth factor receptor 30.021
Foxn1forkhead box N10.021
Otx2orthodenticle homolog 2 (Drosophila)0.021
Mesp1mesoderm posterior 10.020
Barx2BarH-like homeobox 20.020
Nos3nitric oxide synthase 3, endothelial cell0.019
Fgf10fibroblast growth factor 100.019
Klklotho0.018
Sfpi1SFFV proviral integration 10.018
Tnfaip3tumor necrosis factor, alpha-induced protein 30.018
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.018
Fzd10frizzled homolog 10 (Drosophila)0.017
Retret proto-oncogene0.017
Hoxa2homeobox A20.017
Bmpr1abone morphogenetic protein receptor, type 1A0.017
Emx2empty spiracles homolog 2 (Drosophila)0.017
Col2a1collagen, type II, alpha 10.017
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.016
Ptenphosphatase and tensin homolog0.016
Bcl3B-cell leukemia/lymphoma 30.016
Nr5a1nuclear receptor subfamily 5, group A, member 10.016
Hoxd3homeobox D30.016
IhhIndian hedgehog0.016
Tbrachyury0.016
Wnt10bwingless related MMTV integration site 10b0.016
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.016
Ghrgrowth hormone receptor0.016
Hoxa11homeobox A110.015
Foxd2forkhead box D20.015
Prop1paired like homeodomain factor 10.015
Pdx1pancreatic and duodenal homeobox 10.015
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.014
Tbx2T-box 20.014
Adra2badrenergic receptor, alpha 2b0.014
Apcadenomatosis polyposis coli0.014
Lef1lymphoid enhancer binding factor 10.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.988
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.408
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.398
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.333
Vcpvalosin-containing protein0.327
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.253
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.226
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.194
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.190
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.104
Csnk2bcasein kinase 2, beta polypeptide0.087
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.077
Nsfl1cNSFL1 (p97) cofactor (p47)0.076
Nup153nucleoporin 1530.064
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.057
Prmt1protein arginine methyltransferase 10.042
Psmb5proteasome (prosome, macropain) subunit, beta type 50.037
Phbprohibitin0.032
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.030
Pfdn2prefoldin subunit 20.025
Psmd11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.022
Karslysyl-tRNA synthetase0.019
Nudcnuclear distribution gene C homolog (A. nidulans)0.018
Arntaryl hydrocarbon receptor nuclear translocator0.017
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.017
Baz1abromodomain adjacent to zinc finger domain, 1A0.017
Racgap1Rac GTPase-activating protein 10.017
Lin7clin-7 homolog C (C. elegans)0.015
Tcp11t-complex protein 110.015
Stip1stress-induced phosphoprotein 10.014
Taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.013
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.013
Rararetinoic acid receptor, alpha0.013
LOC293989cytochrome P450-like0.013
Etf1eukaryotic translation termination factor 10.012
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.012
Sfrs3splicing factor, arginine/serine-rich 30.012
Aimp1aminoacyl tRNA synthetase complex-interacting multifunctional protein 10.011
Plrg1pleiotropic regulator 1, PRL1 homolog (Arabidopsis)0.011
Crybb3crystallin, beta B30.011
Dbhdopamine beta-hydroxylase (dopamine beta-monooxygenase)0.010