The network for 'positive regulation of transcription initiation from rna polymerase ii promoter' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of transcription initiation from rna polymerase ii promoter

Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.

NameDescriptionProbabilityFunc Analog Organism
SPT16Spt16p0.612
RPN1Rpn1p0.404
NGG1Ngg1p0.275
TAF12Taf12p0.210
TFG1Tfg1p0.177
SPT5Spt5p0.175
TAF5Taf5p0.153
RPO21Rpo21p0.144
TFG2Tfg2p0.137
TAF6Taf6p0.136
RPT2Rpt2p0.089
RPT1Rpt1p0.088
TRA1Tra1p0.082
RPT5Rpt5p0.077
RPT4Rpt4p0.077
RPN2Rpn2p0.076
LEO1Leo1p0.070
RPT6Rpt6p0.069
TAF10Taf10p0.065
CTR9Ctr9p0.063
ADA2Ada2p0.054
TAF9Taf9p0.052
RPN9Rpn9p0.048
HHT1Hht1p0.048
TAF8Taf8p0.045
RTF1Rtf1p0.042
RAD23Rad23p0.041
TFA1Tfa1p0.035
RPN10Rpn10p0.035
WWM1Wwm1p0.035
RPN7Rpn7p0.033
CKA1Cka1p0.032
RSC4Rsc4p0.031
SPT6Spt6p0.030
SRD1Srd1p0.028
SET2Set2p0.027
SEM1Sem1p0.027
LEU2Leu2p0.027
RFA1Rfa1p0.026
PRE10Pre10p0.025
YLR264C-Ahypothetical protein0.025
YLR162Whypothetical protein0.025
TAF7Taf7p0.025
SPT8Spt8p0.025
MER1Mer1p0.024
RPN6Rpn6p0.024
ARG8Arg8p0.023
TAF4Taf4p0.023
YOL038C-Ahypothetical protein0.023
HXT3Hxt3p0.023
SUA7Sua7p0.022
SPL2Spl2p0.021
SUS1Sus1p0.021
ARP10Arp10p0.021
SWC7Swc7p0.021
SPT7Spt7p0.021
YPR157Whypothetical protein0.020
YLR042Chypothetical protein0.020
CUP1-1Cup1-1p0.020
RPN13Rpn13p0.020
AUA1Aua1p0.019
HHT2Hht2p0.019
BAT2Bat2p0.019
YAR068Whypothetical protein0.018
HDA2Hda2p0.018
URA3Ura3p0.018
ATP6Atp6p0.018
PBP1Pbp1p0.018
FMT1Fmt1p0.018
YBR013Chypothetical protein0.018
SPN1Spn1p0.017
PTI1Pti1p0.017
GYL1Gyl1p0.017
YOL013W-Ahypothetical protein0.017
ZPS1Zps1p0.017
TAF11Taf11p0.017
YIR035Chypothetical protein0.017
CHA1Cha1p0.017
SCM4Scm4p0.016
NUP49Nup49p0.016
PRS2Prs2p0.016
HPF1Hpf1p0.016
SUB1Sub1p0.016
BSC1Bsc1p0.016
TYE7Tye7p0.016
ADH2Adh2p0.016
YKR075Chypothetical protein0.016
TAE2Tae2p0.016
MFA2Mfa2p0.016
IZH4Izh4p0.016
POB3Pob3p0.016
MF(ALPHA)2Mf(alpha)2p0.015
YAR066Whypothetical protein0.015
OPT2Opt2p0.015
RRN5Rrn5p0.015
TIF4632Tif4632p0.015
DIC1Dic1p0.015
YPR096Chypothetical protein0.015
YLR363W-Ahypothetical protein0.015
COS12Cos12p0.015
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.999
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.980
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.965
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.835
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.827
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.826
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.778
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.722
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.663
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.623
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.504
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.439
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.436
TBPTATA box binding protein0.412
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.407
NCOA6nuclear receptor coactivator 60.395
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.322
RB1retinoblastoma 10.309
TBX5T-box 50.243
TAF1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa0.239
NBNnibrin0.235
UCHL5ubiquitin carboxyl-terminal hydrolase L50.216
KAT2BK(lysine) acetyltransferase 2B0.201
EP300E1A binding protein p3000.197
CREBBPCREB binding protein0.176
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.154
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.141
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.134
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.119
TP53BP1tumor protein p53 binding protein 10.108
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.098
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.094
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.093
STAG1stromal antigen 10.091
PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 90.085
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.082
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.078
HDAC1histone deacetylase 10.078
MKL1megakaryoblastic leukemia (translocation) 10.077
H2AFXH2A histone family, member X0.071
NCOA3nuclear receptor coactivator 30.061
ARNTaryl hydrocarbon receptor nuclear translocator0.058
TAF1CTATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa0.057
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.048
NCOA1nuclear receptor coactivator 10.047
SUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae)0.047
NCOA2nuclear receptor coactivator 20.047
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.045
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.044
CUX1cut-like homeobox 10.042
TP53tumor protein p530.038
ATMataxia telangiectasia mutated0.036
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.035
TAF1BTATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa0.034
MYOCDmyocardin0.033
HNF4Ahepatocyte nuclear factor 4, alpha0.033
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.033
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.032
E2F3E2F transcription factor 30.032
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.030
GATA4GATA binding protein 40.029
RAD50RAD50 homolog (S. cerevisiae)0.029
ARandrogen receptor0.027
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.027
MYOGmyogenin (myogenic factor 4)0.027
FAM190Bfamily with sequence similarity 190, member B0.026
TRRAPtransformation/transcription domain-associated protein0.026
MYOD1myogenic differentiation 10.025
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.025
NCOA7nuclear receptor coactivator 70.024
RNF8ring finger protein 80.023
GTF2A1general transcription factor IIA, 1, 19/37kDa0.022
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.022
POLR1Apolymerase (RNA) I polypeptide A, 194kDa0.022
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.021
NCOR2nuclear receptor corepressor 20.021
HDGFhepatoma-derived growth factor0.021
NONOnon-POU domain containing, octamer-binding0.021
RUNX1runt-related transcription factor 10.021
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)0.020
MAPK14mitogen-activated protein kinase 140.020
SIRT1sirtuin 10.020
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.019
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.018
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.017
MED26mediator complex subunit 260.017
RBBP5retinoblastoma binding protein 50.016
PAAF1proteasomal ATPase-associated factor 10.016
CD3EAPCD3e molecule, epsilon associated protein0.016
CSNK2A1casein kinase 2, alpha 1 polypeptide0.016
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.016
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa0.016
TAF1ATATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa0.016
MKL2MKL/myocardin-like 20.016
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.015
PSMD5proteasome (prosome, macropain) 26S subunit, non-ATPase, 50.015
PURApurine-rich element binding protein A0.015
POLR1Epolymerase (RNA) I polypeptide E, 53kDa0.015
MCMBPminichromosome maintenance complex binding protein0.015
BRF1BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)0.014
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgf8fibroblast growth factor 81.000
Gli3GLI-Kruppel family member GLI30.999
Pax2paired box gene 20.999
Fgfr2fibroblast growth factor receptor 20.997
Tbx1T-box 10.995
Sox9SRY-box containing gene 90.992
Foxc1forkhead box C10.992
Hand2heart and neural crest derivatives expressed transcript 20.986
Gli2GLI-Kruppel family member GLI20.984
Hand1heart and neural crest derivatives expressed transcript 10.977
Otx2orthodenticle homolog 2 (Drosophila)0.948
Foxc2forkhead box C20.926
Rargretinoic acid receptor, gamma0.922
Lhx1LIM homeobox protein 10.920
Wnt3awingless-related MMTV integration site 3A0.918
Pitx2paired-like homeodomain transcription factor 20.910
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.902
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.902
Rarbretinoic acid receptor, beta0.885
Pax8paired box gene 80.885
Dlx5distal-less homeobox 50.864
Msx1homeobox, msh-like 10.840
Fgf10fibroblast growth factor 100.825
Bmp7bone morphogenetic protein 70.809
Tcfap2atranscription factor AP-2, alpha0.798
Pax3paired box gene 30.788
Gata4GATA binding protein 40.774
Hoxa1homeobox A10.771
Hoxd13homeobox D130.761
Nognoggin0.719
Bmp4bone morphogenetic protein 40.715
Hoxd11homeobox D110.678
Fgfr1fibroblast growth factor receptor 10.676
Ror2receptor tyrosine kinase-like orphan receptor 20.648
Hoxa2homeobox A20.626
Vax1ventral anterior homeobox containing gene 10.604
Mesp1mesoderm posterior 10.593
Smosmoothened homolog (Drosophila)0.579
Prrx1paired related homeobox 10.578
Gdnfglial cell line derived neurotrophic factor0.573
Rararetinoic acid receptor, alpha0.572
Trp63transformation related protein 630.552
Hoxd3homeobox D30.536
Lmx1bLIM homeobox transcription factor 1 beta0.532
Wnt6wingless-related MMTV integration site 60.504
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.469
Gata6GATA binding protein 60.455
Rxraretinoid X receptor alpha0.453
Dkk1dickkopf homolog 1 (Xenopus laevis)0.435
Hmx3H6 homeobox 30.431
Alx4aristaless-like homeobox 40.419
Lmx1aLIM homeobox transcription factor 1 alpha0.416
Foxn1forkhead box N10.412
Ctnnb1catenin (cadherin associated protein), beta 10.403
Chrdchordin0.401
Tbrachyury0.390
Tgfb2transforming growth factor, beta 20.389
Hoxa13homeobox A130.386
Trp53transformation related protein 530.384
Fgf3fibroblast growth factor 30.378
Nkx6-1NK6 homeobox 10.375
En1engrailed 10.366
Isl1ISL1 transcription factor, LIM/homeodomain0.357
Emx2empty spiracles homolog 2 (Drosophila)0.354
Tbx3T-box 30.349
Otx1orthodenticle homolog 1 (Drosophila)0.347
Wnt4wingless-related MMTV integration site 40.333
Twist2twist homolog 2 (Drosophila)0.324
Pax1paired box gene 10.317
Foxa2forkhead box A20.308
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.307
Stat2signal transducer and activator of transcription 20.298
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.294
Msx2homeobox, msh-like 20.293
Socs1suppressor of cytokine signaling 10.273
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.270
Pitx1paired-like homeodomain transcription factor 10.256
Emx1empty spiracles homolog 1 (Drosophila)0.255
Prrx2paired related homeobox 20.250
Efna2ephrin A20.249
Nkx3-2NK3 homeobox 20.247
Hoxa3homeobox A30.246
Barx2BarH-like homeobox 20.239
Fgfr3fibroblast growth factor receptor 30.237
Acvr1activin A receptor, type 10.227
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.225
Adra2badrenergic receptor, alpha 2b0.215
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.213
Wnt1wingless-related MMTV integration site 10.210
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.204
Stat3signal transducer and activator of transcription 30.201
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.195
Zeb1zinc finger E-box binding homeobox 10.194
Gbx2gastrulation brain homeobox 20.192
Foxd2forkhead box D20.185
Barx1BarH-like homeobox 10.182
Lhx5LIM homeobox protein 50.171
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.167
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.164
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.997
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.974
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.560
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.537
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.448
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.416
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.219
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.216
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.188
Nsfl1cNSFL1 (p97) cofactor (p47)0.163
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.134
Vcpvalosin-containing protein0.093
Cops6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.082
Prmt1protein arginine methyltransferase 10.051
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.037
Pin1peptidylprolyl cis/trans isomerase, NIMA-interacting 10.037
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.035
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.034
Ddx1DEAD (Asp-Glu-Ala-Asp) box polypeptide 10.032
Plrg1pleiotropic regulator 1, PRL1 homolog (Arabidopsis)0.026
Stip1stress-induced phosphoprotein 10.020
Strapserine/threonine kinase receptor associated protein0.018
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.017
Tcp1t-complex 10.017
Karslysyl-tRNA synthetase0.017
Nup153nucleoporin 1530.016
Timm17atranslocase of inner mitochondrial membrane 17 homolog A (yeast)0.013
Rad23bRAD23 homolog B (S. cerevisiae)0.013
RragaRas-related GTP binding A0.013
Prpf3PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)0.013
Arntaryl hydrocarbon receptor nuclear translocator0.012
Nudcnuclear distribution gene C homolog (A. nidulans)0.012
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.011
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.011
Cdc25acell division cycle 25 homolog A (S. pombe)0.011
Rchy1ring finger and CHY zinc finger domain containing 10.011
Phaxphosphorylated adaptor for RNA export0.011
Cggbp1CGG triplet repeat binding protein 10.010