The network for 'response to endogenous stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to endogenous stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.

NameDescriptionProbabilityFunc Analog Organism
MKS1Mks1p0.285
STE11Ste11p0.228
RAD52Rad52p0.216
ARO1Aro1p0.120
STE2Ste2p0.109
GPR1Gpr1p0.103
TOR1Tor1p0.087
SIF2Sif2p0.083
CYB2Cyb2p0.080
CDC55Cdc55p0.079
CAD1Cad1p0.073
RTG3Rtg3p0.072
UBP15Ubp15p0.072
URA2Ura2p0.071
BFR1Bfr1p0.070
CPR1Cpr1p0.069
SLG1Slg1p0.068
GND1Gnd1p0.066
ERR3Err3p0.065
PTR3Ptr3p0.064
CAK1Cak1p0.062
MLP2Mlp2p0.060
IZH4Izh4p0.060
BNA3Bna3p0.057
BCK1Bck1p0.057
SIP2Sip2p0.053
CAC2Cac2p0.051
TPK2Tpk2p0.051
HSP82Hsp82p0.051
SET1Set1p0.050
RAS2Ras2p0.050
GAD1Gad1p0.047
STE5Ste5p0.046
TAX4Tax4p0.046
YPT1Ypt1p0.045
KDX1Kdx1p0.045
RVB1Rvb1p0.044
HST1Hst1p0.044
ERR2Err2p0.043
PPH21Pph21p0.043
CMP2Cmp2p0.042
RAS1Ras1p0.042
COT1Cot1p0.041
ERR1Err1p0.040
CIC1Cic1p0.040
RHO1Rho1p0.040
MMS21Mms21p0.039
TPO4Tpo4p0.039
PTC6Ptc6p0.038
CLP1Clp1p0.037
GND2Gnd2p0.036
YPL150Whypothetical protein0.035
NDI1Ndi1p0.035
NBP2Nbp2p0.034
LSM8Lsm8p0.034
CLU1Clu1p0.033
MIG1Mig1p0.033
GSC2Gsc2p0.033
TSL1Tsl1p0.033
APP1App1p0.032
BMH1Bmh1p0.032
MAM3Mam3p0.032
SDA1Sda1p0.031
STE50Ste50p0.031
HOS4Hos4p0.031
RTF1Rtf1p0.030
HOG1Hog1p0.030
JEN1Jen1p0.030
GCD7Gcd7p0.030
TIF6Tif6p0.030
YGR149Whypothetical protein0.029
PGK1Pgk1p0.029
WAR1War1p0.029
SNT1Snt1p0.028
GPM1Gpm1p0.028
DAL80Dal80p0.027
OSH6Osh6p0.027
GPA2Gpa2p0.027
HHT1Hht1p0.027
PCL5Pcl5p0.027
PTC2Ptc2p0.027
END3End3p0.027
AVO2Avo2p0.027
YBR235Whypothetical protein0.026
ARA2Ara2p0.026
CNB1Cnb1p0.026
YMR124Whypothetical protein0.026
DCS2Dcs2p0.026
KCS1Kcs1p0.026
SAM1Sam1p0.026
SNF5Snf5p0.025
NGL3Ngl3p0.025
INP54Inp54p0.025
STE4Ste4p0.025
DDR48Ddr48p0.025
HRK1Hrk1p0.025
YJR085Chypothetical protein0.024
TGL1Tgl1p0.024
SUP35Sup35p0.024
NMA111Nma111p0.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
let-60Protein LET-600.534
pkg-1Protein PKG-10.487
unc-104Protein UNC-1040.297
bar-1Protein BAR-10.287
nhr-67Protein NHR-670.279
daf-11Protein DAF-110.226
vab-3Protein VAB-30.201
egl-15Protein EGL-150.201
eat-6Protein EAT-60.177
tax-6Protein TAX-60.171
mrp-1Protein MRP-10.162
odr-3Protein ODR-30.161
pry-1Protein PRY-10.153
egl-44Protein EGL-440.151
nhr-45Protein NHR-450.146
egl-18Protein EGL-180.142
pmk-1Protein PMK-10.126
Y40C5A.1Protein Y40C5A.10.120
unc-9Protein UNC-90.116
cam-1Protein CAM-10.114
ceh-20Protein CEH-200.109
osm-5Protein OSM-50.108
C12D12.1Protein C12D12.10.108
egl-8Protein EGL-80.108
par-5Protein PAR-50.105
lmn-1Protein LMN-10.103
sas-5Protein SAS-50.101
ptr-11Protein PTR-110.100
abl-1Protein ABL-10.098
dpyd-1Protein DPYD-10.096
hlh-1Protein HLH-10.094
K02A11.3Protein K02A11.30.092
ceh-18Protein CEH-180.087
daf-2Protein DAF-20.086
lag-1Protein LAG-10.086
sma-4Protein SMA-40.084
tag-320Protein TAG-3200.083
mec-4Protein MEC-40.081
osm-6Protein OSM-60.078
ttyh-1Protein TTYH-10.077
sms-1Protein SMS-10.077
ccch-1Protein CCCH-10.077
plc-1Protein PLC-10.076
dlk-1Protein DLK-10.076
unc-29Protein UNC-290.072
CELE_R10D12.1Protein R10D12.10.071
pdfr-1Protein PDFR-10.071
sdha-1Protein SDHA-10.071
kin-20Protein KIN-200.070
sax-7Protein SAX-70.068
nhr-25Protein NHR-250.066
mat-3Protein MAT-30.065
peb-1Protein PEB-10.065
aak-2Protein AAK-20.062
ogdh-1Protein OGDH-10.061
vit-6Protein VIT-60.061
F28E10.1Protein F28E10.10.061
unc-73Protein UNC-730.059
vit-4Protein VIT-40.057
hlh-11Protein HLH-110.057
ace-1Protein ACE-10.056
nipi-3Protein NIPI-30.055
CELE_C08F8.6Protein C08F8.60.055
tbb-2Protein TBB-20.055
itx-1Protein ITX-10.055
vit-5Protein VIT-50.054
F13H6.1Protein F13H6.10.052
F37H8.5Protein F37H8.50.051
sma-3Protein SMA-30.050
daf-1Protein DAF-10.050
itr-1Protein ITR-10.050
pkc-1Protein PKC-10.050
tba-4Protein TBA-40.049
tag-196Protein TAG-1960.049
cpr-4Protein CPR-40.048
lin-25Protein LIN-250.048
chaf-1Protein CHAF-10.048
vit-2Protein VIT-20.047
hlh-2Protein HLH-20.047
C05D10.4Protein C05D10.40.047
ida-1Protein IDA-10.046
daf-16Protein DAF-160.044
che-2Protein CHE-20.044
cyp-35C1Protein CYP-35C10.043
apy-1Protein APY-10.043
pat-3Protein PAT-30.043
nhr-6Protein NHR-60.043
plc-3Protein PLC-30.042
goa-1Protein GOA-10.042
srp-6Protein SRP-60.042
pha-4Protein PHA-40.042
pde-4Protein PDE-40.041
gtl-1Protein GTL-10.041
unc-68Protein UNC-680.041
T19D12.6Protein T19D12.60.040
F46C5.6Protein F46C5.60.040
tag-253Protein TAG-2530.040
ceh-44Protein CEH-440.040
rhi-1Protein RHI-10.040
CELE_Y57G11C.15Protein Y57G11C.150.039
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
vasavasa homolog0.894
pcnaproliferating cell nuclear antigen0.889
bmp2bbone morphogenetic protein 2b0.798
spry4sprouty (Drosophila) homolog 40.787
fgf3fibroblast growth factor 30.749
efnb2aephrin B2a0.615
chdchordin0.586
notch1anotch homolog 1a0.580
fabp11afatty acid binding protein 11a0.566
wnt10awingless-type MMTV integration site family, member 10a0.555
bmp2abone morphogenetic protein 2a0.537
dharmadharma0.518
sox17SRY-box containing gene 170.510
fgf8afibroblast growth factor 8 a0.488
fgf4fibroblast growth factor 40.425
ctgfconnective tissue growth factor0.423
pitx3paired-like homeodomain transcription factor 30.401
mef2camyocyte enhancer factor 2ca0.395
apoebapolipoprotein Eb0.393
esr1estrogen receptor 10.393
ptch2patched 20.374
tp53tumor protein p530.349
tbx20T-box 200.328
wnt9awingless-type MMTV integration site family, member 9A0.327
foxp2forkhead box P20.327
oxtloxytocin-like0.313
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.301
robo3roundabout homolog 30.299
crabp1bcellular retinoic acid binding protein 1b0.297
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.284
snai1asnail homolog 1a (Drosophila)0.283
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.281
sox9bSRY-box containing gene 9b0.277
mstnbmyostatin b0.271
gata6GATA-binding protein 60.264
pax7apaired box gene 7a0.253
trpv6transient receptor potential cation channel, subfamily V, member 60.245
wnt2wingless-type MMTV integration site family member 20.235
per2period homolog 2 (Drosophila)0.235
rarabretinoic acid receptor, alpha b0.233
avplarginine vasopressin-like0.233
igf1insulin-like growth factor 10.231
gnrh3gonadotropin-releasing hormone 30.229
krit1KRIT1, ankyrin repeat containing0.224
foxa2forkhead box A20.221
pomcaproopiomelanocortin a0.218
ventventral expressed homeobox0.216
fabp10afatty acid binding protein 10a, liver basic0.206
gamtguanidinoacetate N-methyltransferase0.204
mapk1mitogen-activated protein kinase 10.197
spry2sprouty homolog 20.196
osr1odd-skipped related 1 (Drosophila)0.195
cyp1acytochrome P450, family 1, subfamily A0.194
maomonoamine oxidase0.188
sox32SRY-box containing gene 320.187
fgfr1afibroblast growth factor receptor 1a0.185
mef2amyocyte enhancer factor 2a0.181
thtyrosine hydroxylase0.180
pax8paired box gene 80.179
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.177
dlx4adistal-less homeobox gene 4a0.175
wnt1wingless-type MMTV integration site family, member 10.173
tshbthyroid stimulating hormone, beta subunit0.172
tbx1T-box 10.172
runx2arunt-related transcription factor 2a0.171
cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.169
oprk1opioid receptor, kappa 10.169
sfrp1asecreted frizzled-related protein 1a0.164
rag1recombination activating gene 10.164
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.163
vtg3vitellogenin 3, phosvitinless0.163
jag1ajagged 1a0.163
oprd1aopioid receptor, delta 1a0.162
her12hairy-related 120.162
slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.162
igf1rainsulin-like growth factor 1a receptor0.162
tnfrsfatumor necrosis factor receptor superfamily, member a0.161
btg2B-cell translocation gene 20.160
gh1growth hormone 10.158
ef1aelongation factor 1-alpha0.156
tie1endothelium-specific receptor tyrosine kinase 10.155
aldobaldolase b, fructose-bisphosphate0.152
gli2bGLI-Kruppel family member GLI2b0.150
ddcdopa decarboxylase0.147
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.147
nadl1.1neural adhesion molecule L1.10.145
shbgsex hormone binding globulin0.145
psen1presenilin 10.144
paqr8progestin and adipoQ receptor family member VIII0.144
bmp1abone morphogenetic protein 1a0.144
oprm1opioid receptor, mu 10.144
gli2aGLI-Kruppel family member GLI2a0.144
esr2bestrogen receptor 2b0.141
lft2lefty20.141
ntrk2bneurotrophic tyrosine kinase, receptor, type 2b0.140
vcanaversican a0.140
lef1lymphocyte enhancer binding factor 10.136
trpm7transient receptor potential cation channel, subfamily M, member 70.135
inhainhibin, alpha0.135
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.135
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dlg1discs large 10.938
rlrolled0.825
dmdiminutive0.815
NNotch0.765
EgfrEpidermal growth factor receptor0.715
nejnejire0.705
MadMothers against dpp0.681
apapterous0.644
EcREcdysone receptor0.634
Akt1CG4006 gene product from transcript CG4006-RA0.613
foxoforkhead box, sub-group O0.609
panpangolin0.601
ftz-f1ftz transcription factor 10.601
Sir2CG5216 gene product from transcript CG5216-RA0.572
argosCG4531 gene product from transcript CG4531-RA0.565
putpunt0.517
S6kRPS6-p70-protein kinase0.508
neuroliginCG13772 gene product from transcript CG13772-RA0.470
Hsp68Heat shock protein 680.464
cicubitus interruptus0.458
Trx-2thioredoxin-20.457
hthhomothorax0.455
porporcupine0.443
TbhTyramine beta hydroxylase0.437
Stat92ESignal-transducer and activator of transcription protein at 92E0.421
babobaboon0.420
DadDaughters against dpp0.418
skpACG16983 gene product from transcript CG16983-RD0.409
tkvthickveins0.384
Ras85DRas oncogene at 85D0.380
lealeak0.378
Atg13Autophagy-specific gene 130.370
LamCLamin C0.364
cswcorkscrew0.361
sinaseven in absentia0.355
SsdpSequence-specific single-stranded DNA-binding protein0.349
PezCG9493 gene product from transcript CG9493-RA0.347
MhcMyosin heavy chain0.329
ttvtout-velu0.327
CG7998CG7998 gene product from transcript CG7998-RA0.319
InRInsulin-like receptor0.317
wtswarts0.315
uspultraspiracle0.313
phlpole hole0.292
Spn27ASerpin 27A0.282
mbcmyoblast city0.279
knknot0.274
Pi3K92ECG4141 gene product from transcript CG4141-RB0.265
shgshotgun0.259
bazbazooka0.257
TrhTryptophan hydroxylase0.248
hephemipterous0.247
rprreaper0.240
TorTarget of rapamycin0.240
Ilp2Insulin-like peptide 20.237
sflsulfateless0.236
Hsp70AbHeat-shock-protein-70Ab0.232
MetMethoprene-tolerant0.231
Nup153Nucleoporin 1530.229
Pka-C1cAMP-dependent protein kinase 10.219
jebjelly belly0.217
rolsrolling pebbles0.213
AblAbl tyrosine kinase0.212
Pkc98EProtein C kinase 98E0.207
snssticks and stones0.206
Sulf1Sulfated0.205
ushu-shaped0.204
Ilp5Insulin-like peptide 50.204
Gyc76CGuanylyl cyclase at 76C0.203
roboroundabout0.202
dcodiscs overgrown0.200
Ugt35aUDP-glycosyltransferase 35a0.199
frufruitless0.198
CycGCyclin G0.197
edechinoid0.194
eveeven skipped0.194
shishibire0.189
Cdc42CG12530 gene product from transcript CG12530-RA0.189
TlToll0.188
NFATNFAT homolog0.188
Hsp70AaHeat-shock-protein-70Aa0.188
drkdownstream of receptor kinase0.187
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.186
NrgNeuroglian0.184
TequilaCG4821 gene product from transcript CG4821-RE0.183
rictorrapamycin-insensitive companion of Tor0.176
eyeyeless0.173
fz2frizzled 20.172
fkhfork head0.169
GLazGlial Lazarillo0.167
sNPF-Rshort neuropeptide F receptor0.166
CG17450CG17450 gene product from transcript CG17450-RB0.163
TBPHCG10327 gene product from transcript CG10327-RC0.163
tantantalus0.162
sogshort gastrulation0.161
Rac2CG8556 gene product from transcript CG8556-RA0.157
btlbreathless0.154
dsxdoublesex0.152
WnkCG7177 gene product from transcript CG7177-RA0.151
CG1347CG1347 gene product from transcript CG1347-RB0.151
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism