The network for 'leading strand elongation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leading strand elongation

The synthesis of DNA from a template strand in the 5' to 3' direction; leading strand elongation is continuous as it proceeds in the same direction as the replication fork.

NameDescriptionProbabilityFunc Analog Organism
RFC3Rfc3p0.818
RFC4Rfc4p0.670
POL12Pol12p0.632
RFC5Rfc5p0.576
RFC2Rfc2p0.487
DPB2Dpb2p0.245
PSF1Psf1p0.160
PRI2Pri2p0.153
CDC9Cdc9p0.092
SLD5Sld5p0.090
SLD2Sld2p0.090
POL30Pol30p0.077
ACM1Acm1p0.056
RFC1Rfc1p0.040
POL3Pol3p0.035
CDC21Cdc21p0.033
SRD1Srd1p0.028
CTF18Ctf18p0.028
LEU2Leu2p0.026
MCM6Mcm6p0.024
PRI1Pri1p0.023
DLS1Dls1p0.023
CDC45Cdc45p0.022
MER1Mer1p0.022
YLR162Whypothetical protein0.022
YAR068Whypothetical protein0.021
YLR264C-Ahypothetical protein0.021
MF(ALPHA)2Mf(alpha)2p0.020
URA3Ura3p0.020
YOL038C-Ahypothetical protein0.020
ARP10Arp10p0.019
ARG8Arg8p0.019
SPL2Spl2p0.019
ATP6Atp6p0.018
PSF2Psf2p0.018
DPB11Dpb11p0.018
YIR035Chypothetical protein0.017
POL32Pol32p0.017
SWC7Swc7p0.017
MF(ALPHA)1Mf(alpha)1p0.017
YPR157Whypothetical protein0.016
ZPS1Zps1p0.016
YLR042Chypothetical protein0.015
HXT3Hxt3p0.015
PRS2Prs2p0.015
YLR040Chypothetical protein0.014
CUP1-1Cup1-1p0.014
PHM6Phm6p0.014
YOL013W-Ahypothetical protein0.014
HOHop0.014
AUA1Aua1p0.014
HPF1Hpf1p0.014
AQY2Aqy2p0.013
YBR013Chypothetical protein0.013
MCM10Mcm10p0.013
SCM4Scm4p0.013
BSC1Bsc1p0.013
IZH4Izh4p0.013
NPA3Npa3p0.013
FMT1Fmt1p0.013
YAR066Whypothetical protein0.012
CRP1Crp1p0.012
ECO1Eco1p0.012
SFT1Sft1p0.012
COS12Cos12p0.012
ALT2Alt2p0.012
DIC1Dic1p0.012
REV1Rev1p0.012
CPD1Cpd1p0.012
YAL064Whypothetical protein0.011
YAL037C-Ahypothetical protein0.011
SEN54Sen54p0.011
OPT2Opt2p0.011
UPS3Ups3p0.011
NRG2Nrg2p0.011
PTR2Ptr2p0.011
YLL053Chypothetical protein0.011
RAT1Rat1p0.011
YGR035Chypothetical protein0.011
YPR096Chypothetical protein0.011
MET8Met8p0.011
ADH2Adh2p0.010
RNP1Rnp1p0.010
TSC3Tsc3p0.010
YPL067Chypothetical protein0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RFC2replication factor C (activator 1) 2, 40kDa1.000
RFC1replication factor C (activator 1) 1, 145kDa1.000
RFC5replication factor C (activator 1) 5, 36.5kDa0.999
RFC3replication factor C (activator 1) 3, 38kDa0.999
RPA1replication protein A1, 70kDa0.987
RPA2replication protein A2, 32kDa0.963
RFC4replication factor C (activator 1) 4, 37kDa0.963
RPA3replication protein A3, 14kDa0.949
PCNAproliferating cell nuclear antigen0.939
MCM5minichromosome maintenance complex component 50.511
PRIM1primase, DNA, polypeptide 1 (49kDa)0.364
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.229
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.121
MCM3minichromosome maintenance complex component 30.087
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.064
PRIM2primase, DNA, polypeptide 2 (58kDa)0.049
CHTF18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)0.042
DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 90.023
ORC1origin recognition complex, subunit 10.019
ITGB3BPintegrin beta 3 binding protein (beta3-endonexin)0.019
POLA2polymerase (DNA directed), alpha 2 (70kD subunit)0.018
PARP2poly (ADP-ribose) polymerase 20.015
DONSONdownstream neighbor of SON0.014
SMC1Astructural maintenance of chromosomes 1A0.014
MSH6mutS homolog 6 (E. coli)0.014
RAD17RAD17 homolog (S. pombe)0.014
UNGuracil-DNA glycosylase0.013
PRPS1phosphoribosyl pyrophosphate synthetase 10.013
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism