The network for 'receptor recycling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

receptor recycling

The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.

NameDescriptionProbabilityFunc Analog Organism
YLR264C-Ahypothetical protein0.014
YOL038C-Ahypothetical protein0.011
YLR162Whypothetical protein0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gria2aglutamate receptor, ionotropic, AMPA 2a0.692
gria1bglutamate receptor, ionotropic, AMPA 1b0.340
gria3aglutamate receptor, ionotropic, AMPA 3a0.331
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.236
chmp4bchromatin modifying protein 4B0.223
gria1aglutamate receptor, ionotropic, AMPA 1a0.141
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.138
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.123
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.113
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.109
gpc4glypican 40.100
gria3bglutamate receptor, ionotrophic, AMPA 3b0.085
fynaFYN oncogene related to SRC, FGR, YES a0.082
vangl2vang-like 2 (van gogh, Drosophila)0.068
gria2bglutamate receptor, ionotropic, AMPA 2b0.065
scn8aasodium channel, voltage-gated, type VIII, alpha a0.063
gria4aglutamate receptor, ionotropic, AMPA 4a0.063
gria4bglutamate receptor, ionotropic, AMPA 4b0.058
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.056
ints6integrator complex subunit 60.055
lama1laminin, alpha 10.055
trpc5transient receptor potential cation channel, subfamily C, member 50.052
atl1atlastin GTPase 10.050
ppp3cbprotein phosphatase 3, catalytic subunit, beta isozyme0.048
crb2acrumbs homolog 2a0.039
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.039
chrndcholinergic receptor, nicotinic, delta polypeptide0.038
gc3guanylyl cyclase 30.037
guk1guanylate kinase 10.037
gnat1guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 10.036
rap1bRAS related protein 1b0.034
hegheart of glass0.033
foxh1forkhead box H10.032
rbp4lretinol binding protein 4, like0.032
oepone-eyed pinhead0.032
gpr182G protein-coupled receptor 1820.031
tie1endothelium-specific receptor tyrosine kinase 10.031
aftphaaftiphilin a0.031
nxph1neurexophilin 10.031
prkcqprotein kinase C, theta0.030
synj1synaptojanin 10.030
opn1sw2opsin 1 (cone pigments), short-wave-sensitive 20.028
cacna1abcalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b0.028
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.028
vps4bvacuolar protein sorting 4b (yeast)0.028
c1qtnf4C1q and tumor necrosis factor related protein 40.026
sdcbpsyndecan binding protein (syntenin)0.026
csrp1acysteine and glycine-rich protein 1a0.026
gmdsGDP-mannose 4,6-dehydratase0.025
LOC555504novel protocadherin protein0.024
trim13tripartite motif-containing 130.024
adcyap1aadenylate cyclase activating polypeptide 1a0.024
scribscribbled homolog (Drosophila)0.024
hnrnpkheterogeneous nuclear ribonucleoprotein K0.024
LOC100005295acetylcholine receptor subunit beta-like0.023
slc6a17solute carrier family 6, member 170.023
irbpinterphotoreceptor retinoid-binding protein0.023
rem2RAS (RAD and GEM)-like GTP binding 20.023
diras1aDIRAS family, GTP-binding RAS-like 1a0.023
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.022
akt2v-akt murine thymoma viral oncogene homolog 20.021
syt13synaptotagmin XIII0.021
crb1crumbs homolog 1 (Drosophila)0.020
plcg1phospholipase C, gamma 10.020
aph1banterior pharynx defective 1B0.020
dlg1discs, large (Drosophila) homolog 10.019
mibmind bomb0.019
nr1d2anuclear receptor subfamily 1, group D, member 2a0.019
aldh16a1aldehyde dehydrogenase 16 family, member A10.019
tll1tolloid-like 10.019
spg11spastic paraplegia 110.019
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.019
lrrc15leucine rich repeat containing 150.019
crxcone-rod homeobox0.019
itga6aintegrin, alpha 6a0.019
col17a1acollagen, type XVII, alpha 1a0.018
LOC565839tumor necrosis factor alpha-induced protein 2-like0.018
slc1a2asolute carrier family 1 (glial high affinity glutamate transporter), member 2a0.018
grk7aG-protein-coupled receptor kinase 7a0.018
zfand5azinc finger, AN1-type domain 5a0.018
opn1sw1opsin 1 (cone pigments), short-wave-sensitive 10.018
slc39a3solute carrier family 39 (zinc transporter), member 30.018
taldo1transaldolase 10.018
cldn5bclaudin 5b0.017
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PcafCG4107 gene product from transcript CG4107-RA0.019
CspCysteine string protein0.017
CragCalmodulin-binding protein related to a Rab3 GDP/GTP exchange protein0.014
Snap25Synapse protein 250.013
tipEtemperature-induced paralytic E0.013
ZnT63CCG17723 gene product from transcript CG17723-RD0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSEN1presenilin 10.282
PKP4plakophilin 40.101
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.090
FLNBfilamin B, beta0.084
CLASP1cytoplasmic linker associated protein 10.074
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.063
CNKSR2connector enhancer of kinase suppressor of Ras 20.053
SNAP23synaptosomal-associated protein, 23kDa0.053
MYO6myosin VI0.042
ARRB1arrestin, beta 10.038
DLG1discs, large homolog 1 (Drosophila)0.024
ZFYVE9zinc finger, FYVE domain containing 90.023
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.022
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.019
TJP2tight junction protein 2 (zona occludens 2)0.017
PLEKHJ1pleckstrin homology domain containing, family J member 10.015
ZBTB16zinc finger and BTB domain containing 160.015
STX4syntaxin 40.015
HACE1HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 10.014
EEA1early endosome antigen 10.013
SMURF2SMAD specific E3 ubiquitin protein ligase 20.013
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.013
PSEN2presenilin 2 (Alzheimer disease 4)0.012
SQSTM1sequestosome 10.012
FLNAfilamin A, alpha0.012
TBK1TANK-binding kinase 10.012
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.012
FUNDC2FUN14 domain containing 20.010
NBR1neighbor of BRCA1 gene 10.010
MAGI1membrane associated guanylate kinase, WW and PDZ domain containing 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Snap25synaptosomal-associated protein 250.804
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.509
Arrb1arrestin, beta 10.504
Psen1presenilin 10.495
Appamyloid beta (A4) precursor protein0.441
Ednraendothelin receptor type A0.424
Dlg4discs, large homolog 4 (Drosophila)0.421
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.419
Notch1Notch gene homolog 1 (Drosophila)0.353
Ren1renin 1 structural0.210
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.207
Stx1asyntaxin 1A (brain)0.187
Grip1glutamate receptor interacting protein 10.185
Lamtor3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.179
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.164
Stx12syntaxin 120.140
Psen2presenilin 20.135
Vegfavascular endothelial growth factor A0.133
Vldlrvery low density lipoprotein receptor0.121
Emx1empty spiracles homolog 1 (Drosophila)0.111
Chd7chromodomain helicase DNA binding protein 70.095
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.088
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.085
Stx7syntaxin 70.072
Loxlysyl oxidase0.068
Rxraretinoid X receptor alpha0.066
Nr2f6nuclear receptor subfamily 2, group F, member 60.064
Agtrapangiotensin II, type I receptor-associated protein0.064
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.062
Clstn1calsyntenin 10.060
Dync1i2dynein cytoplasmic 1 intermediate chain 20.059
Rab11aRAB11a, member RAS oncogene family0.056
Nostrinnitric oxide synthase trafficker0.055
Plp1proteolipid protein (myelin) 10.052
Mkl2MKL/myocardin-like 20.050
Gria3glutamate receptor, ionotropic, AMPA3 (alpha 3)0.048
Notch2Notch gene homolog 2 (Drosophila)0.047
Atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.045
Aph1aanterior pharynx defective 1a homolog (C. elegans)0.042
Nrp1neuropilin 10.042
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.039
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.035
Syvn1synovial apoptosis inhibitor 1, synoviolin0.034
Lrp8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor0.032
Dll1delta-like 1 (Drosophila)0.032
Foxi3forkhead box I30.031
Crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.028
Ptpn9protein tyrosine phosphatase, non-receptor type 90.025
Lrrk2leucine-rich repeat kinase 20.022
Tgfbr2transforming growth factor, beta receptor II0.021
Nr3c2nuclear receptor subfamily 3, group C, member 20.020
Ces1fcarboxylesterase 1F0.019
Gsta3glutathione S-transferase, alpha 30.018
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.018
Tbx1T-box 10.018
Erlin2ER lipid raft associated 20.017
Chmp2bchromatin modifying protein 2B0.017
Atp6v1c1ATPase, H+ transporting, lysosomal V1 subunit C10.017
Rarbretinoic acid receptor, beta0.016
C78339expressed sequence C783390.016
Sdcbpsyndecan binding protein0.016
Ldlrlow density lipoprotein receptor0.015
NapbN-ethylmaleimide sensitive fusion protein attachment protein beta0.015
Vps26avacuolar protein sorting 26 homolog A (yeast)0.015
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.014
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.014
Gng3guanine nucleotide binding protein (G protein), gamma 30.014
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.014
Gsk3bglycogen synthase kinase 3 beta0.013
Ccdc90bcoiled-coil domain containing 90B0.013
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.012
Exoc4exocyst complex component 40.012
Pi4kbphosphatidylinositol 4-kinase, catalytic, beta polypeptide0.012
Fxc1fractured callus expressed transcript 10.012
Akr7a5aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)0.012
Beta-shemoglobin subunit beta-1-like0.012
Atg2aATG2 autophagy related 2 homolog A (S. cerevisiae)0.012
Atp6v1g1ATPase, H+ transporting, lysosomal V1 subunit G10.012
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.012
Rab5aRAB5A, member RAS oncogene family0.011
Zfp110zinc finger protein 1100.011
Neurod6neurogenic differentiation 60.011
Plxnd1plexin D10.011
Sult1d1sulfotransferase family 1D, member 10.011
Akap8lA kinase (PRKA) anchor protein 8-like0.011
Atp6v0eATPase, H+ transporting, lysosomal V0 subunit E0.011
Inmtindolethylamine N-methyltransferase0.011
5730494N06RikRIKEN cDNA 5730494N06 gene0.010
Cyfip1cytoplasmic FMR1 interacting protein 10.010
Smap2stromal membrane-associated GTPase-activating protein 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gria2glutamate receptor, ionotropic, AMPA 20.977
Grip1glutamate receptor interacting protein 10.912
Gria1glutamate receptor, ionotropic, AMPA 10.626
Gria3glutamate receptor, ionotrophic, AMPA 30.608
Pick1protein interacting with PRKCA 10.254
Col5a2collagen, type V, alpha 20.091
Agap2ArfGAP with GTPase domain, ankyrin repeat and PH domain 20.020
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.020
Grm7glutamate receptor, metabotropic 70.019
Hk1hexokinase 10.017
Epha7Eph receptor A70.016
Map2microtubule-associated protein 20.011
Gria4glutamate receptor, ionotrophic, AMPA 40.011
Dlgap1discs, large (Drosophila) homolog-associated protein 10.011
Cacng2calcium channel, voltage-dependent, gamma subunit 20.011
Ppfia4protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 40.011
Nrcamneuronal cell adhesion molecule0.011
Fn1fibronectin 10.011
Arf1ADP-ribosylation factor 10.010