The network for 'sterol transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sterol transport

The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

NameDescriptionProbabilityFunc Analog Organism
OSH2Osh2p0.771
OSH7Osh7p0.744
DRS2Drs2p0.422
BUL2Bul2p0.266
AUS1Aus1p0.198
SUT1Sut1p0.176
MID2Mid2p0.124
NBP2Nbp2p0.118
PRY1Pry1p0.116
FLC1Flc1p0.096
TGL1Tgl1p0.095
YLR042Chypothetical protein0.083
YOL013W-Ahypothetical protein0.075
HPF1Hpf1p0.072
SCW4Scw4p0.071
HXT4Hxt4p0.069
RAX1Rax1p0.067
STE20Ste20p0.064
SRD1Srd1p0.064
TPO4Tpo4p0.061
HES1Hes1p0.060
IST1Ist1p0.058
PDR11Pdr11p0.058
CDC55Cdc55p0.057
SFT2Sft2p0.057
SKM1Skm1p0.056
SCW10Scw10p0.054
DID2Did2p0.053
PTR2Ptr2p0.051
YPL272Chypothetical protein0.050
PRP28Prp28p0.049
YLR162Whypothetical protein0.049
YGL235Whypothetical protein0.049
HRB1Hrb1p0.048
YAR068Whypothetical protein0.048
YOL038C-Ahypothetical protein0.048
ERG5Erg5p0.047
YLR264C-Ahypothetical protein0.046
ARP10Arp10p0.046
YMR317Whypothetical protein0.045
YNR063Whypothetical protein0.045
YGR205Whypothetical protein0.044
LEU2Leu2p0.043
TIR1Tir1p0.042
ATF1Atf1p0.041
YGR035Chypothetical protein0.041
URA3Ura3p0.040
YDL241Whypothetical protein0.040
HUG1Hug1p0.040
MER1Mer1p0.039
SSP1Ssp1p0.039
ARG8Arg8p0.039
SFT1Sft1p0.038
YSR3Ysr3p0.038
ZPS1Zps1p0.037
SWH1Swh1p0.037
YNL024Chypothetical protein0.037
ICS2Ics2p0.037
VPS55Vps55p0.037
SCS2Scs2p0.036
BDH1Bdh1p0.036
SPL2Spl2p0.035
YNL018Chypothetical protein0.035
FMT1Fmt1p0.035
ATP6Atp6p0.035
SET4Set4p0.034
RSA1Rsa1p0.034
SIW14Siw14p0.034
YIR035Chypothetical protein0.034
YPR157Whypothetical protein0.033
BSC1Bsc1p0.033
COX5BCox5bp0.033
CPD1Cpd1p0.033
NRG2Nrg2p0.032
CLN3Cln3p0.032
RNP1Rnp1p0.032
YHR045Whypothetical protein0.032
CUP1-1Cup1-1p0.031
YCK1Yck1p0.031
CAB4Cab4p0.031
SWM2Swm2p0.031
YBR013Chypothetical protein0.031
BCK1Bck1p0.031
PCL2Pcl2p0.031
IES2Ies2p0.030
SRO77Sro77p0.030
AGC1Agc1p0.030
NIS1Nis1p0.030
COS9Cos9p0.030
DIF1Dif1p0.030
COS12Cos12p0.030
YJR120Whypothetical protein0.029
YPL168Whypothetical protein0.029
PHM6Phm6p0.029
BUR6Bur6p0.029
ERI1Eri1p0.029
AUA1Aua1p0.029
RHO1Rho1p0.029
YHK8Yhk8p0.029
PAU2Pau2p0.028
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
plc-1Protein PLC-10.033
dlk-1Protein DLK-10.031
CELE_E01G4.6Protein E01G4.60.028
C31E10.5Protein C31E10.50.028
bli-1Protein BLI-10.026
T23G11.4Protein T23G11.40.026
qua-1Protein QUA-10.024
F54D1.6Protein F54D1.60.023
F37B4.10Protein F37B4.100.021
T09B4.5Protein T09B4.50.021
sago-1Protein SAGO-10.020
clec-180Protein CLEC-1800.020
ZC247.1Protein ZC247.10.020
T06D8.1Protein T06D8.10.019
F37C4.5Protein F37C4.50.019
C35E7.5Protein C35E7.50.019
CELE_Y11D7A.5Protein Y11D7A.50.018
klp-17Protein KLP-170.018
lron-10Protein LRON-100.018
ptr-11Protein PTR-110.018
cas-1Protein CAS-10.018
hsp-43Protein HSP-430.018
CELE_K09H11.1Protein K09H11.10.017
CELE_F15A8.6Protein F15A8.60.017
F16C3.2Protein F16C3.20.017
H03A11.2Protein H03A11.20.017
mlt-10Protein MLT-100.017
srp-6Protein SRP-60.017
hst-6Protein HST-60.016
K03A11.5Protein K03A11.50.016
ptr-4Protein PTR-40.016
F08G12.2Protein F08G12.20.016
ZK180.6Protein ZK180.60.016
T14D7.1Protein T14D7.10.015
C07E3.3Protein C07E3.30.015
F27E5.3Protein F27E5.30.015
osm-8Protein OSM-80.015
atg-4.2Protein ATG-4.20.015
clh-1Protein CLH-10.015
smd-1Protein SMD-10.015
skr-7Protein SKR-70.015
cpd-1Protein CPD-10.015
atg-16.2Protein ATG-16.20.015
let-19Protein LET-190.015
col-128Protein COL-1280.014
col-111Protein COL-1110.014
gcy-12Protein GCY-120.014
cdh-7Protein CDH-70.014
abu-13Protein ABU-130.014
CELE_R02D3.3Protein R02D3.30.014
F13B6.1Protein F13B6.10.014
clp-4Protein CLP-40.014
tag-297Protein TAG-2970.014
paa-1Protein PAA-10.014
ptr-15Protein PTR-150.014
ZC434.3Protein ZC434.30.014
T16G1.2Protein T16G1.20.013
rol-3Protein ROL-30.013
CELE_Y53F4B.36Protein Y53F4B.360.013
mltn-9Protein MLTN-90.013
tps-1Protein TPS-10.013
CELE_F10G7.5Protein F10G7.50.013
H03E18.1Protein H03E18.10.013
nrf-5Protein NRF-50.013
mrp-5Protein MRP-50.013
F35C11.4Protein F35C11.40.013
dos-2Protein DOS-20.013
F52D10.2Protein F52D10.20.013
mig-15Protein MIG-150.013
rbc-1Protein RBC-10.013
C33F10.14Protein C33F10.140.012
col-79Protein COL-790.012
C01A2.5Protein C01A2.50.012
CELE_F28G4.4Protein F28G4.40.012
lron-7Protein LRON-70.012
CELE_T06G6.6Protein T06G6.60.012
dpy-20Protein DPY-200.012
F45E4.6Protein F45E4.60.012
CELE_ZK1025.3Protein ZK1025.30.012
CELE_ZK1025.2Protein ZK1025.20.012
C28H8.1Protein C28H8.10.012
ttr-50Protein TTR-500.012
H43E16.1Protein H43E16.10.012
T03G11.6Protein T03G11.60.012
dct-17Protein DCT-170.012
crm-1Protein CRM-10.012
T04B8.5Protein T04B8.50.012
Y26E6A.2Protein Y26E6A.20.012
bah-1Protein BAH-10.012
pcm-1Protein PCM-10.012
alg-1Protein ALG-10.011
F26C11.1Protein F26C11.10.011
F39C12.1Protein F39C12.10.011
anc-1Protein ANC-10.011
C42D8.1Protein C42D8.10.011
rpm-1Protein RPM-10.011
mlt-11Protein MLT-110.011
igdb-2Protein IGDB-20.011
CELE_F31E8.4Protein F31E8.40.011
ZK353.4Protein ZK353.40.011
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
APOA1apolipoprotein A-I1.000
APOEapolipoprotein E0.999
C1QAcomplement component 1, q subcomponent, A chain0.998
ALBalbumin0.992
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.979
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.974
APOC1apolipoprotein C-I0.939
HPhaptoglobin0.936
ABCG5ATP-binding cassette, sub-family G (WHITE), member 50.901
CREBBPCREB binding protein0.864
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.836
A2Malpha-2-macroglobulin0.804
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.789
ABCG8ATP-binding cassette, sub-family G (WHITE), member 80.746
APOA2apolipoprotein A-II0.746
LRRK2leucine-rich repeat kinase 20.741
C1QCcomplement component 1, q subcomponent, C chain0.732
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.701
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.642
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.604
APOC2apolipoprotein C-II0.491
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.460
C1QBcomplement component 1, q subcomponent, B chain0.438
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.435
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.426
CAV2caveolin 20.420
APOC3apolipoprotein C-III0.410
APPamyloid beta (A4) precursor protein0.404
BCL3B-cell CLL/lymphoma 30.398
TTRtransthyretin0.367
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.260
RRAGARas-related GTP binding A0.248
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.243
EPS15epidermal growth factor receptor pathway substrate 150.242
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.236
LCATlecithin-cholesterol acyltransferase0.232
CHUKconserved helix-loop-helix ubiquitous kinase0.213
EGFRepidermal growth factor receptor0.205
LDLRlow density lipoprotein receptor0.198
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.183
S100A10S100 calcium binding protein A100.174
PELI3pellino homolog 3 (Drosophila)0.173
CHMP1Achromatin modifying protein 1A0.173
EP300E1A binding protein p3000.159
CTSBcathepsin B0.145
INSIG1insulin induced gene 10.135
FGAfibrinogen alpha chain0.132
KAT2BK(lysine) acetyltransferase 2B0.130
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.120
MED15mediator complex subunit 150.116
SMOsmoothened homolog (Drosophila)0.112
RRAGCRas-related GTP binding C0.109
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.108
APOBapolipoprotein B (including Ag(x) antigen)0.106
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.105
IQGAP1IQ motif containing GTPase activating protein 10.105
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.102
PDZK1PDZ domain containing 10.095
TRAF6TNF receptor-associated factor 60.093
SORBS2sorbin and SH3 domain containing 20.087
TNIP2TNFAIP3 interacting protein 20.087
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.085
ABCF3ATP-binding cassette, sub-family F (GCN20), member 30.083
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.080
HNF4Ahepatocyte nuclear factor 4, alpha0.078
ACADMacyl-CoA dehydrogenase, C-4 to C-12 straight chain0.075
ANXA1annexin A10.074
PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)0.074
NSFN-ethylmaleimide-sensitive factor0.074
MARCOmacrophage receptor with collagenous structure0.074
IRAK2interleukin-1 receptor-associated kinase 20.072
SH3RF3SH3 domain containing ring finger 30.070
SREBF1sterol regulatory element binding transcription factor 10.069
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.068
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.067
LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.065
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.065
NCOA1nuclear receptor coactivator 10.061
PTPRFprotein tyrosine phosphatase, receptor type, F0.060
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.059
PLTPphospholipid transfer protein0.058
RPL18Aribosomal protein L18a0.058
VAMP4vesicle-associated membrane protein 40.057
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.055
OSBPL9oxysterol binding protein-like 90.055
DKK1dickkopf homolog 1 (Xenopus laevis)0.055
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.054
C7orf59chromosome 7 open reading frame 590.053
DHCR77-dehydrocholesterol reductase0.052
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.052
SQLEsqualene epoxidase0.052
MSTO1misato homolog 1 (Drosophila)0.051
PTPN1protein tyrosine phosphatase, non-receptor type 10.051
FOXO3forkhead box O30.051
SWAP70SWAP switching B-cell complex 70kDa subunit0.050
F7coagulation factor VII (serum prothrombin conversion accelerator)0.048
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.045
PDIA3protein disulfide isomerase family A, member 30.045
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.045
CANXcalnexin0.044
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apoeapolipoprotein E1.000
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.995
Lrp1low density lipoprotein receptor-related protein 10.993
Ldlrlow density lipoprotein receptor0.971
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.934
Npc1Niemann Pick type C10.919
Leprleptin receptor0.910
Dab1disabled homolog 1 (Drosophila)0.855
Apoa1apolipoprotein A-I0.758
Foxa2forkhead box A20.714
Ppargperoxisome proliferator activated receptor gamma0.555
Traf6TNF receptor-associated factor 60.543
Ghrgrowth hormone receptor0.526
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.499
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.400
Abcg5ATP-binding cassette, sub-family G (WHITE), member 50.363
Gnrh1gonadotropin releasing hormone 10.350
Abcg8ATP-binding cassette, sub-family G (WHITE), member 80.342
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.290
Plgplasminogen0.274
Lpin1lipin 10.273
Lyz2lysozyme 20.229
Ptenphosphatase and tensin homolog0.187
Plin1perilipin 10.182
Myd88myeloid differentiation primary response gene 880.178
Rdh8retinol dehydrogenase 80.178
Cav1caveolin 1, caveolae protein0.160
Nos3nitric oxide synthase 3, endothelial cell0.157
Clpscolipase, pancreatic0.156
Gpr116G protein-coupled receptor 1160.145
Nr5a1nuclear receptor subfamily 5, group A, member 10.133
Nr1h3nuclear receptor subfamily 1, group H, member 30.131
Ahsgalpha-2-HS-glycoprotein0.127
Scd1stearoyl-Coenzyme A desaturase 10.118
Celcarboxyl ester lipase0.117
Abhd5abhydrolase domain containing 50.117
RragcRas-related GTP binding C0.115
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.115
Ctrb1chymotrypsinogen B10.111
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.110
Klklotho0.108
Appamyloid beta (A4) precursor protein0.108
Abcg1ATP-binding cassette, sub-family G (WHITE), member 10.108
Ctnnb1catenin (cadherin associated protein), beta 10.106
Tbx3T-box 30.103
Ambpalpha 1 microglobulin/bikunin0.098
S100a10S100 calcium binding protein A10 (calpactin)0.097
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.097
Procprotein C0.096
Slc12a6solute carrier family 12, member 60.095
Pnpla2patatin-like phospholipase domain containing 20.087
Fgf9fibroblast growth factor 90.085
Vldlrvery low density lipoprotein receptor0.085
Sycnsyncollin0.085
Pltpphospholipid transfer protein0.082
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.081
Ift88intraflagellar transport 88 homolog (Chlamydomonas)0.080
Sqlesqualene epoxidase0.078
Klf15Kruppel-like factor 150.075
Rab11aRAB11a, member RAS oncogene family0.075
Pick1protein interacting with C kinase 10.075
Fggfibrinogen gamma chain0.073
Mapk8ip2mitogen-activated protein kinase 8 interacting protein 20.073
Mertkc-mer proto-oncogene tyrosine kinase0.072
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.072
F2coagulation factor II0.068
Inhainhibin alpha0.068
Dhcr77-dehydrocholesterol reductase0.068
Hnf4ahepatic nuclear factor 4, alpha0.068
Irak4interleukin-1 receptor-associated kinase 40.068
Ern2endoplasmic reticulum (ER) to nucleus signalling 20.067
C3complement component 30.064
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.063
Cficomplement component factor i0.063
Itih4inter alpha-trypsin inhibitor, heavy chain 40.062
Notch2Notch gene homolog 2 (Drosophila)0.061
Srfserum response factor0.060
Spink4serine peptidase inhibitor, Kazal type 40.060
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.059
Tskstestis-specific serine kinase substrate0.059
Grngranulin0.058
Spp2secreted phosphoprotein 20.057
Rs1retinoschisis (X-linked, juvenile) 1 (human)0.056
Nr0b2nuclear receptor subfamily 0, group B, member 20.055
Arandrogen receptor0.054
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.054
Cdhr5cadherin-related family member 50.054
Cela2achymotrypsin-like elastase family, member 2A0.053
Fabp4fatty acid binding protein 4, adipocyte0.053
Lmf1lipase maturation factor 10.052
Hand1heart and neural crest derivatives expressed transcript 10.052
Flt1FMS-like tyrosine kinase 10.051
Aldobaldolase B, fructose-bisphosphate0.051
Lgals3lectin, galactose binding, soluble 30.050
Lgals2lectin, galactose-binding, soluble 20.050
Apoc4apolipoprotein C-IV0.050
Cd47CD47 antigen (Rh-related antigen, integrin-associated signal transducer)0.049
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.049
Apoa5apolipoprotein A-V0.049
Mpv17MpV17 mitochondrial inner membrane protein0.049
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100362824caveolin 2-like0.953
Cav1caveolin 1, caveolae protein0.859
Cav2caveolin 20.744
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.066
Fabp1fatty acid binding protein 1, liver0.064
Galnt1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)0.062
Zfp36zinc finger protein 360.060
Spp2secreted phosphoprotein 20.058
Ambpalpha-1-microglobulin/bikunin precursor0.033
Sgpl1sphingosine-1-phosphate lyase 10.028
Ddit4DNA-damage-inducible transcript 40.027
Akt2v-akt murine thymoma viral oncogene homolog 20.027
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.025
Apohapolipoprotein H (beta-2-glycoprotein I)0.024
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.022
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.020
Gabarapl2GABA(A) receptor-associated protein like 20.020
Errfi1ERBB receptor feedback inhibitor 10.016
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.016
Actn4actinin alpha 40.015
Car5acarbonic anhydrase 5a, mitochondrial0.015
Apoa1apolipoprotein A-I0.014
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.014
Tcf12transcription factor 120.014
Ctsccathepsin C0.014
Sgk1serum/glucocorticoid regulated kinase 10.013
Fabp4fatty acid binding protein 4, adipocyte0.011
Otcornithine carbamoyltransferase0.011
Emp1epithelial membrane protein 10.010