The network for 'trna modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trna modification

The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

NameDescriptionProbabilityFunc Analog Organism
ELP3Elp3p1.000
IKI3Iki3p0.999
YNL022Chypothetical protein0.999
PUS4Pus4p0.998
DEG1Deg1p0.998
ELP4Elp4p0.997
ELP6Elp6p0.993
PUS7Pus7p0.991
KTI12Kti12p0.989
URM1Urm1p0.988
PUS1Pus1p0.987
IKI1Iki1p0.981
NCS6Ncs6p0.980
NCS2Ncs2p0.959
TRM8Trm8p0.939
ELP2Elp2p0.934
TRM9Trm9p0.883
TRM1Trm1p0.882
SMM1Smm1p0.880
MTO1Mto1p0.777
TRM11Trm11p0.722
UBA4Uba4p0.716
LOS1Los1p0.715
SLM3Slm3p0.698
KAE1Kae1p0.669
MEX67Mex67p0.657
TPA1Tpa1p0.645
YIL096Chypothetical protein0.592
YHR003Chypothetical protein0.589
YBR242Whypothetical protein0.581
BER1Ber1p0.536
RRP6Rrp6p0.450
TRM10Trm10p0.431
YKL027Whypothetical protein0.424
PCC1Pcc1p0.410
SUA5Sua5p0.410
TAD2Tad2p0.365
DPH2Dph2p0.363
TAE1Tae1p0.361
DUS4Dus4p0.346
MSS1Mss1p0.335
RIM2Rim2p0.329
RTT10Rtt10p0.325
TAD3Tad3p0.320
POP8Pop8p0.319
KTI11Kti11p0.293
DBP5Dbp5p0.264
YPK3Ypk3p0.231
TRM2Trm2p0.215
TRM112Trm112p0.215
YCR051Whypothetical protein0.210
RER2Rer2p0.207
YJR003Chypothetical protein0.203
DAS2Das2p0.202
NAR1Nar1p0.192
TYW3Tyw3p0.191
YCK2Yck2p0.188
CDC123Cdc123p0.184
DRE2Dre2p0.182
GFD2Gfd2p0.178
POP3Pop3p0.178
TRM13Trm13p0.171
POP1Pop1p0.169
HIS6His6p0.166
YIR035Chypothetical protein0.156
YLR419Whypothetical protein0.156
NRD1Nrd1p0.148
MDM36Mdm36p0.147
RAT1Rat1p0.147
AIR2Air2p0.146
PUS6Pus6p0.146
AIR1Air1p0.145
YML096Whypothetical protein0.142
YGR210Chypothetical protein0.137
YHR122Whypothetical protein0.137
ATS1Ats1p0.134
TAN1Tan1p0.134
RNH70Rnh70p0.132
UME1Ume1p0.130
TAF8Taf8p0.129
YPL245Whypothetical protein0.129
RKM4Rkm4p0.129
TRM44Trm44p0.128
YML082Whypothetical protein0.127
NBP2Nbp2p0.123
YBR141Chypothetical protein0.123
PPX1Ppx1p0.121
ADE8Ade8p0.117
MOD5Mod5p0.117
AGE1Age1p0.117
IME4Ime4p0.117
NBA1Nba1p0.116
GIS4Gis4p0.116
RPP1Rpp1p0.113
CUE2Cue2p0.109
PCF11Pcf11p0.108
LEU9Leu9p0.107
DML1Dml1p0.104
TRM82Trm82p0.103
SWM2Swm2p0.102
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_W09G3.7Protein W09G3.70.065
F48E8.6Protein F48E8.60.065
CELE_Y75B8A.14Protein Y75B8A.140.049
elpc-3Protein ELPC-30.026
C18A3.3Protein C18A3.30.024
C47E12.7Protein C47E12.70.021
csr-1Protein CSR-10.020
ruvb-1Protein RUVB-10.020
byn-1Protein BYN-10.019
figl-1Protein FIGL-10.017
T27A3.2Protein T27A3.20.017
helq-1Protein HELQ-10.014
ppw-2Protein PPW-20.013
eif-3.BProtein EIF-3.B0.012
cmd-1Protein CMD-10.012
W07E6.2Protein W07E6.20.011
CELE_ZK1236.1Protein ZK1236.10.010
dao-5Protein DAO-50.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Zfrp8Zinc finger protein RP-80.258
Vap-33-1CG5014 gene product from transcript CG5014-RB0.215
CkIIbetaCasein kinase II beta subunit0.171
CG6550CG6550 gene product from transcript CG6550-RA0.101
CG1074CG1074 gene product from transcript CG1074-RA0.098
TgttRNA-guanine transglycosylase0.077
Actr13EActin-related protein 13E0.072
eIF2B-epsilonCG3806 gene product from transcript CG3806-RB0.068
Fer1HCHFerritin 1 heavy chain homologue0.065
CG3434CG3434 gene product from transcript CG3434-RA0.063
CG4159CG4159 gene product from transcript CG4159-RA0.053
CG6388CG6388 gene product from transcript CG6388-RA0.052
Dpit47DNA polymerase interacting tpr containing protein of 47kD0.048
skpACG16983 gene product from transcript CG16983-RD0.046
CG5451CG5451 gene product from transcript CG5451-RA0.042
CG10189CG10189 gene product from transcript CG10189-RA0.042
CG10463CG10463 gene product from transcript CG10463-RA0.041
CG4858CG4858 gene product from transcript CG4858-RA0.041
CG9630CG9630 gene product from transcript CG9630-RA0.041
Art8Arginine methyltransferase 80.037
CG14544CG14544 gene product from transcript CG14544-RA0.037
CG6751CG6751 gene product from transcript CG6751-RA0.035
CG12134CG12134 gene product from transcript CG12134-RA0.035
mtsmicrotubule star0.034
CG2972CG2972 gene product from transcript CG2972-RA0.033
CG17904CG17904 gene product from transcript CG17904-RA0.031
CG6607CG6607 gene product from transcript CG6607-RA0.030
SucbCG10622 gene product from transcript CG10622-RA0.029
CG15738CG15738 gene product from transcript CG15738-RA0.029
wdbwiderborst0.029
elavembryonic lethal abnormal vision0.028
CG3808CG3808 gene product from transcript CG3808-RA0.027
CG9839CG9839 gene product from transcript CG9839-RA0.027
CG14812CG14812 gene product from transcript CG14812-RA0.027
Dcp1Decapping protein 10.026
Mocs2Molybdopterin synthase 20.026
CG12267CG12267 gene product from transcript CG12267-RB0.026
CG7741CG7741 gene product from transcript CG7741-RA0.025
CG5589CG5589 gene product from transcript CG5589-RA0.023
ChcClathrin heavy chain0.023
CG5190CG5190 gene product from transcript CG5190-RA0.023
Rrp4CG3931 gene product from transcript CG3931-RA0.023
Psf3CG2222 gene product from transcript CG2222-RA0.022
Nop56CG13849 gene product from transcript CG13849-RA0.022
CG4933CG4933 gene product from transcript CG4933-RA0.022
CG1575CG1575 gene product from transcript CG1575-RA0.022
CG7265CG7265 gene product from transcript CG7265-RA0.021
Dbp45ADEAD box protein 45A0.021
Arf79FADP ribosylation factor 79F0.020
snisniffer0.020
CG13192CG13192 gene product from transcript CG13192-RA0.020
CG11859CG11859 gene product from transcript CG11859-RA0.020
metlmethyltransferase-like0.020
Rs1CG2173 gene product from transcript CG2173-RA0.020
Gfat2Glutamine:fructose-6-phosphate aminotransferase 20.019
CG8132CG8132 gene product from transcript CG8132-RA0.019
Prp31CG6876 gene product from transcript CG6876-RA0.019
CG8005CG8005 gene product from transcript CG8005-RA0.019
brpbruchpilot0.019
CG7889CG7889 gene product from transcript CG7889-RA0.018
larkCG8597 gene product from transcript CG8597-RD0.018
CG3004CG3004 gene product from transcript CG3004-RA0.018
CG14985CG14985 gene product from transcript CG14985-RB0.018
fz2frizzled 20.018
pex2peroxin 20.017
CG7747CG7747 gene product from transcript CG7747-RA0.017
l(2)09851lethal (2) 098510.017
CG7341CG7341 gene product from transcript CG7341-RB0.017
Elp2Elongator complex protein 20.017
ranshiCG9793 gene product from transcript CG9793-RA0.017
Ipk2CG13688 gene product from transcript CG13688-RA0.016
CG12413CG12413 gene product from transcript CG12413-RA0.016
CG8064CG8064 gene product from transcript CG8064-RA0.016
CG15717CG15717 gene product from transcript CG15717-RA0.016
CG1671CG1671 gene product from transcript CG1671-RA0.016
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.016
CG11447CG11447 gene product from transcript CG11447-RA0.016
CG6724CG6724 gene product from transcript CG6724-RA0.016
Elp3Elongator complex protein 30.016
4EHPCG33100 gene product from transcript CG33100-RA0.015
CG6144CG6144 gene product from transcript CG6144-RB0.015
NleNotchless0.015
mbmmushroom body miniature0.015
ferrochelataseCG2098 gene product from transcript CG2098-RC0.015
cortoCG2530 gene product from transcript CG2530-RA0.015
CG9286CG9286 gene product from transcript CG9286-RA0.015
PP2A-B'CG7913 gene product from transcript CG7913-RK0.015
Aats-proProlyl-tRNA synthetase0.015
skfskiff0.015
CG4679CG4679 gene product from transcript CG4679-RA0.015
GmerGDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase0.014
CG5126CG5126 gene product from transcript CG5126-RA0.014
CG13185CG13185 gene product from transcript CG13185-RB0.014
CG2789CG2789 gene product from transcript CG2789-RA0.014
RpI1RNA polymerase I subunit0.014
CG2915CG2915 gene product from transcript CG2915-RB0.014
CG3448CG3448 gene product from transcript CG3448-RB0.014
crncrooked neck0.014
CG9799CG9799 gene product from transcript CG9799-RA0.014
CG4908CG4908 gene product from transcript CG4908-RB0.014
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
IKBKAPinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein1.000
ELP3elongation protein 3 homolog (S. cerevisiae)0.997
ELP2elongation protein 2 homolog (S. cerevisiae)0.997
ELP4elongation protein 4 homolog (S. cerevisiae)0.936
MDM4Mdm4 p53 binding protein homolog (mouse)0.138
TP53RKTP53 regulating kinase0.083
MMS19MMS19 nucleotide excision repair homolog (S. cerevisiae)0.078
DVL3dishevelled, dsh homolog 3 (Drosophila)0.061
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.057
ASCC2activating signal cointegrator 1 complex subunit 20.050
NVLnuclear VCP-like0.048
CSNK1Ecasein kinase 1, epsilon0.046
DDX24DEAD (Asp-Glu-Ala-Asp) box polypeptide 240.037
XPO5exportin 50.034
CEBPECCAAT/enhancer binding protein (C/EBP), epsilon0.032
MCCmutated in colorectal cancers0.032
OCLNoccludin0.030
ANKRD28ankyrin repeat domain 280.028
COASYCoA synthase0.028
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.025
NUBP2nucleotide binding protein 2 (MinD homolog, E. coli)0.025
SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.024
PPP6R3protein phosphatase 6, regulatory subunit 30.024
MYST2MYST histone acetyltransferase 20.023
SARSseryl-tRNA synthetase0.022
TSEN2tRNA splicing endonuclease 2 homolog (S. cerevisiae)0.022
HTThuntingtin0.021
FASTKD2FAST kinase domains 20.021
MBD1methyl-CpG binding domain protein 10.020
GTF3C1general transcription factor IIIC, polypeptide 1, alpha 220kDa0.019
IGBP1immunoglobulin (CD79A) binding protein 10.019
PPP1R14Aprotein phosphatase 1, regulatory (inhibitor) subunit 14A0.019
C19orf60chromosome 19 open reading frame 600.019
TBL3transducin (beta)-like 30.019
TELO2TEL2, telomere maintenance 2, homolog (S. cerevisiae)0.018
DVL1dishevelled, dsh homolog 1 (Drosophila)0.017
FAM110Cfamily with sequence similarity 110, member C0.017
FAM110Afamily with sequence similarity 110, member A0.017
FAM96Bfamily with sequence similarity 96, member B0.016
DVL2dishevelled, dsh homolog 2 (Drosophila)0.016
BBS10Bardet-Biedl syndrome 100.016
FAM173Afamily with sequence similarity 173, member A0.015
PSAT1phosphoserine aminotransferase 10.015
LENG1leukocyte receptor cluster (LRC) member 10.015
OSGEPL1O-sialoglycoprotein endopeptidase-like 10.015
ASNSasparagine synthetase (glutamine-hydrolyzing)0.014
PRMT6protein arginine methyltransferase 60.014
HES1hairy and enhancer of split 1, (Drosophila)0.013
NKIRAS2NFKB inhibitor interacting Ras-like 20.013
SAV1salvador homolog 1 (Drosophila)0.012
RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 20.011
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.011
VPS4Avacuolar protein sorting 4 homolog A (S. cerevisiae)0.011
HEATR2HEAT repeat containing 20.011
MAP3K7mitogen-activated protein kinase kinase kinase 70.011
ARMC6armadillo repeat containing 60.011
KATNB1katanin p80 (WD repeat containing) subunit B 10.011
FASTKFas-activated serine/threonine kinase0.011
C9orf142chromosome 9 open reading frame 1420.010
NOC4Lnucleolar complex associated 4 homolog (S. cerevisiae)0.010
C12orf66chromosome 12 open reading frame 660.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Eif3deukaryotic translation initiation factor 3, subunit D0.391
Ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.326
Wdr74WD repeat domain 740.319
Per2period homolog 2 (Drosophila)0.222
Srmspermidine synthase0.132
Yarstyrosyl-tRNA synthetase0.101
Per1period homolog 1 (Drosophila)0.085
Mrps18bmitochondrial ribosomal protein S18B0.079
Vps25vacuolar protein sorting 25 (yeast)0.067
Mybbp1aMYB binding protein (P160) 1a0.056
Ddx41DEAD (Asp-Glu-Ala-Asp) box polypeptide 410.051
Wdr46WD repeat domain 460.050
Tsr1TSR1, 20S rRNA accumulation, homolog (yeast)0.050
Smyd5SET and MYND domain containing 50.048
Rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.045
Arntlaryl hydrocarbon receptor nuclear translocator-like0.045
Sarsseryl-aminoacyl-tRNA synthetase0.043
Lrrc59leucine rich repeat containing 590.041
Eif3beukaryotic translation initiation factor 3, subunit B0.041
Sox4SRY-box containing gene 40.038
Varsvalyl-tRNA synthetase0.033
Parnpoly(A)-specific ribonuclease (deadenylation nuclease)0.033
Imp4IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.032
Noc4lnucleolar complex associated 4 homolog (S. cerevisiae)0.031
Dus1ldihydrouridine synthase 1-like (S. cerevisiae)0.031
Ppanpeter pan homolog (Drosophila)0.030
Rrp9RRP9, small subunit (SSU) processome component, homolog (yeast)0.027
Rcc2regulator of chromosome condensation 20.027
Eftud2elongation factor Tu GTP binding domain containing 20.025
Drg2developmentally regulated GTP binding protein 20.025
Rrp1ribosomal RNA processing 1 homolog (S. cerevisiae)0.023
Elac2elaC homolog 2 (E. coli)0.023
2610027L16RikRIKEN cDNA 2610027L16 gene0.023
Eif6eukaryotic translation initiation factor 60.022
Grwd1glutamate-rich WD repeat containing 10.022
Ntf3neurotrophin 30.020
Bop1block of proliferation 10.019
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.019
Prepprolyl endopeptidase0.019
Lsg1large subunit GTPase 1 homolog (S. cerevisiae)0.018
Cry2cryptochrome 2 (photolyase-like)0.018
Ccdc86coiled-coil domain containing 860.017
Tbrg4transforming growth factor beta regulated gene 40.017
Dph5DPH5 homolog (S. cerevisiae)0.017
Prpf6PRP6 pre-mRNA splicing factor 6 homolog (yeast)0.017
Pwp2PWP2 periodic tryptophan protein homolog (yeast)0.016
Nubp2nucleotide binding protein 20.015
Prpf31PRP31 pre-mRNA processing factor 31 homolog (yeast)0.015
Rrp36ribosomal RNA processing 36 homolog (S. cerevisiae)0.014
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.014
Larsleucyl-tRNA synthetase0.014
Clockcircadian locomotor output cycles kaput0.013
Rbm19RNA binding motif protein 190.013
Afg3l1AFG3(ATPase family gene 3)-like 1 (yeast)0.012
Ddx49DEAD (Asp-Glu-Ala-Asp) box polypeptide 490.012
Exosc5exosome component 50.012
Xpo5exportin 50.012
Sox11SRY-box containing gene 110.012
Tomm40translocase of outer mitochondrial membrane 40 homolog (yeast)0.011
Garsglycyl-tRNA synthetase0.011
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.011
Utp20UTP20, small subunit (SSU) processome component, homolog (yeast)0.010
Cry1cryptochrome 1 (photolyase-like)0.010
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism