The network for 'generation of precursor metabolites and energy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

generation of precursor metabolites and energy

The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.

NameDescriptionProbabilityFunc Analog Organism
GSY2Gsy2p0.998
CYT1Cyt1p0.986
GSY1Gsy1p0.980
FBA1Fba1p0.975
PET9Pet9p0.969
GPM1Gpm1p0.938
ENO1Eno1p0.928
ADH1Adh1p0.919
PGM2Pgm2p0.915
COR1Cor1p0.911
SDH2Sdh2p0.894
ENO2Eno2p0.888
PGK1Pgk1p0.848
COX4Cox4p0.840
COX13Cox13p0.837
GIP2Gip2p0.825
PDC1Pdc1p0.820
CDC19Cdc19p0.803
COX6Cox6p0.801
TPI1Tpi1p0.799
QCR7Qcr7p0.788
ACB1Acb1p0.779
RPM2Rpm2p0.773
QCR8Qcr8p0.761
PFK1Pfk1p0.743
SDS22Sds22p0.736
GLG1Glg1p0.728
PGI1Pgi1p0.726
COX5ACox5ap0.724
QCR10Qcr10p0.717
IDH2Idh2p0.706
GLG2Glg2p0.692
RIP1Rip1p0.643
CYC1Cyc1p0.635
REG1Reg1p0.626
PCL8Pcl8p0.617
SAP4Sap4p0.608
GND1Gnd1p0.605
MDH1Mdh1p0.600
GLC7Glc7p0.584
COX2Cox2p0.568
HXK2Hxk2p0.556
HAP2Hap2p0.542
CIT1Cit1p0.535
MSS51Mss51p0.533
PET309Pet309p0.517
TDH2Tdh2p0.516
TDH3Tdh3p0.508
HAP4Hap4p0.508
MBR1Mbr1p0.504
NDI1Ndi1p0.496
BMH1Bmh1p0.482
PPH22Pph22p0.468
SDH3Sdh3p0.465
NDE1Nde1p0.461
GLC3Glc3p0.461
IRA2Ira2p0.438
COX12Cox12p0.425
HXK1Hxk1p0.420
ADH3Adh3p0.397
ATP2Atp2p0.393
GDB1Gdb1p0.378
COQ9Coq9p0.368
SAM1Sam1p0.367
SDH1Sdh1p0.366
SLG1Slg1p0.360
SHY1Shy1p0.358
COX15Cox15p0.358
COX14Cox14p0.336
BCK2Bck2p0.327
ATP3Atp3p0.325
ADH5Adh5p0.318
COX9Cox9p0.317
UGP1Ugp1p0.317
YNR014Whypothetical protein0.316
YNR034W-Ahypothetical protein0.316
ATP14Atp14p0.312
COBCobp0.310
TAZ1Taz1p0.300
YLR345Whypothetical protein0.299
QCR9Qcr9p0.290
CDC34Cdc34p0.286
GPH1Gph1p0.286
GFA1Gfa1p0.285
ATP6Atp6p0.281
PDH1Pdh1p0.278
ATP1Atp1p0.276
SOL1Sol1p0.273
TIP41Tip41p0.271
EMI5Emi5p0.258
SCO1Sco1p0.257
PIG2Pig2p0.255
ICY1Icy1p0.254
ODC1Odc1p0.252
UPS2Ups2p0.252
ERR3Err3p0.246
QCR6Qcr6p0.245
CIR2Cir2p0.244
MIC17Mic17p0.239
ATP15Atp15p0.236
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
nuo-2Protein NUO-20.159
F58F12.1Protein F58F12.10.145
atp-3Protein ATP-30.109
har-1Protein HAR-10.078
F01G4.6Protein F01G4.60.077
ucr-1Protein UCR-10.067
pdhb-1Protein PDHB-10.062
CELE_H28G03.1Protein H28G03.10.060
Y67D2.3Protein Y67D2.30.060
B0491.5Protein B0491.50.059
F36A2.7Protein F36A2.70.058
R05G6.7Protein R05G6.70.054
ant-1.1Protein ANT-1.10.053
nol-1Protein NOL-10.053
CELE_F27D4.1Protein F27D4.10.052
K11G12.5Protein K11G12.50.050
dlst-1Protein DLST-10.049
dld-1Protein DLD-10.049
F29B9.11Protein F29B9.110.049
coq-1Protein COQ-10.048
cts-1Protein CTS-10.047
nuo-5Protein NUO-50.046
atp-5Protein ATP-50.044
idhb-1Protein IDHB-10.044
CELE_Y69A2AR.18Protein Y69A2AR.180.043
idha-1Protein IDHA-10.042
F53A2.7Protein F53A2.70.040
pry-1Protein PRY-10.040
immt-1Protein IMMT-10.038
ogdh-1Protein OGDH-10.035
F46H5.3Protein F46H5.30.035
ard-1Protein ARD-10.034
lin-9Protein LIN-90.034
gdh-1Protein GDH-10.034
tag-147Protein TAG-1470.033
CELE_F29C4.2Protein F29C4.20.033
mev-1Protein MEV-10.032
F32B6.2Protein F32B6.20.032
fum-1Protein FUM-10.032
F23H11.5Protein F23H11.50.032
nuo-4Protein NUO-40.031
T20H4.5Protein T20H4.50.031
prdx-3Protein PRDX-30.030
atp-2Protein ATP-20.029
men-1Protein MEN-10.029
tomm-40Protein TOMM-400.029
skn-1Protein SKN-10.028
sdhb-1Protein SDHB-10.027
mdh-1Protein MDH-10.026
C16A3.5Protein C16A3.50.026
zyg-8Protein ZYG-80.026
F45H10.2Protein F45H10.20.026
pde-4Protein PDE-40.025
C34C12.8Protein C34C12.80.025
atp-4Protein ATP-40.024
H28O16.1Protein H28O16.10.024
rpia-1Protein RPIA-10.024
F21A10.2Protein F21A10.20.024
mai-2Protein MAI-20.023
CELE_Y67H2A.5Protein Y67H2A.50.023
CELE_F32A11.1Protein F32A11.10.023
kat-1Protein KAT-10.022
sdha-1Protein SDHA-10.022
Y53G8AL.2Protein Y53G8AL.20.022
coq-8Protein COQ-80.021
cco-1Protein CCO-10.021
F37C12.3Protein F37C12.30.021
smp-1Protein SMP-10.021
sdhd-1Protein SDHD-10.021
itr-1Protein ITR-10.021
acdh-13Protein ACDH-130.020
nduf-7Protein NDUF-70.020
alh-3Protein ALH-30.020
F58F9.7Protein F58F9.70.020
goa-1Protein GOA-10.020
Y51H1A.3Protein Y51H1A.30.019
F48E8.6Protein F48E8.60.019
CELE_F23C8.5Protein F23C8.50.019
lag-1Protein LAG-10.019
tkt-1Protein TKT-10.019
hsp-60Protein HSP-600.019
Y37E3.17Protein Y37E3.170.018
dlat-1Protein DLAT-10.018
acs-22Protein ACS-220.018
CELE_F59C6.5Protein F59C6.50.017
isp-1Protein ISP-10.017
gpd-3Protein GPD-30.017
daf-22Protein DAF-220.017
pal-1Protein PAL-10.017
fln-1Protein FLN-10.017
F49E2.5Protein F49E2.50.017
cyc-1Protein CYC-10.016
F57B10.3Protein F57B10.30.016
btbd-10Protein BTBD-100.016
K07C5.2Protein K07C5.20.016
R53.5Protein R53.50.015
T20B12.1Protein T20B12.10.015
mdh-2Protein MDH-20.015
sucl-2Protein SUCL-20.015
CELE_W09C5.8Protein W09C5.80.014
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.961
ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.750
gpiaglucose phosphate isomerase a0.446
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.374
ivdisovaleryl Coenzyme A dehydrogenase0.257
etfaelectron-transfer-flavoprotein, alpha polypeptide0.169
ldhalactate dehydrogenase A40.092
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.078
uqcrc2bubiquinol-cytochrome c reductase core protein IIb0.065
uqcrc1ubiquinol-cytochrome c reductase core protein I0.064
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.063
ndufa10NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 100.063
cfl2lcofilin 2, like0.060
eno1enolase 1, (alpha)0.058
hk1hexokinase 10.057
chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.055
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.051
lrpprcleucine-rich PPR-motif containing0.048
epas1bendothelial PAS domain protein 1b0.045
ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.044
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.042
aglamylo-1, 6-glucosidase, 4-alpha-glucanotransferase0.038
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.038
cyc1cytochrome c-10.037
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.034
idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.033
myoz1bmyozenin 1b0.033
aldoaaaldolase a, fructose-bisphosphate, a0.031
ahr2aryl hydrocarbon receptor 20.029
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.028
aldh7a1aldehyde dehydrogenase 7 family, member A10.028
ocrloculocerebrorenal syndrome of Lowe0.027
mycamyelocytomatosis oncogene a0.027
sod1superoxide dismutase 1, soluble0.027
ndufa4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 40.026
c1qtnf4C1q and tumor necrosis factor related protein 40.025
ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 60.024
aco2aconitase 2, mitochondrial0.023
eef2l2eukaryotic translation elongation factor 2, like 20.023
setd5SET domain containing 50.022
junjun proto-oncogene0.022
got2aglutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)0.022
zgc:63663zgc:636630.022
tp53tumor protein p530.022
pgam1bphosphoglycerate mutase 1b0.020
il6rinterleukin 6 receptor0.020
pdhbpyruvate dehydrogenase (lipoamide) beta0.020
mc3rmelanocortin 3 receptor0.020
ctgfconnective tissue growth factor0.019
prdx3peroxiredoxin 30.019
tpm3tropomyosin 30.018
sod2superoxide dismutase 2, mitochondrial0.018
gpx4aglutathione peroxidase 4a0.018
ncam2neural cell adhesion molecule 20.018
cox7a2cytochrome c oxidase, subunit VIIa 20.018
zbtb4zinc finger and BTB domain containing 40.017
acaa2acetyl-CoA acyltransferase 20.016
npy8arneuropeptide Y receptor Y8a0.016
ptgeslprostaglandin E synthase 2-like0.016
cecr1acat eye syndrome chromosome region, candidate 1a0.016
mstnbmyostatin b0.015
timm17atranslocase of inner mitochondrial membrane 17 homolog A (yeast)0.015
tpi1btriosephosphate isomerase 1b0.015
sumo1SMT3 suppressor of mif two 3 homolog 1 (yeast)0.015
abcd3aATP-binding cassette, sub-family D (ALD), member 3a0.015
insrainsulin receptor a0.014
fgf6afibroblast growth factor 6a0.014
ndufb8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 80.014
hccsholocytochrome c synthase0.014
tomm34translocase of outer mitochondrial membrane 340.014
pcnaproliferating cell nuclear antigen0.013
zgc:73329zgc:733290.013
zgc:158138zgc:1581380.013
tshbthyroid stimulating hormone, beta subunit0.013
rtn4areticulon 4a0.013
gpd1bglycerol-3-phosphate dehydrogenase 1b0.013
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.013
ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.013
dlstdihydrolipoamide S-succinyltransferase0.013
irf2bp2ainterferon regulatory factor 2 binding protein 2a0.013
LOC100003330melanocortin-2 receptor accessory protein 2-like0.013
slc25a11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.013
hsp90a.2heat shock protein 90-alpha 20.013
cox8acytochrome c oxidase subunit 8a0.013
adrb2aadrenergic receptor, beta 2a0.012
catcatalase0.012
uqcrc2aubiquinol-cytochrome c reductase core protein IIa0.012
mc5rbmelanocortin 5b receptor0.012
zgc:56466zgc:564660.012
aldocbaldolase C, fructose-bisphosphate, b0.012
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.012
mc4rmelanocortin 4 receptor0.012
cox7ccytochrome c oxidase, subunit VIIc0.012
esr1estrogen receptor 10.012
ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.011
nbl1neuroblastoma, suppression of tumorigenicity 10.011
tnni2a.3troponin I, skeletal, fast 2a.30.011
slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.011
zgc:92631zgc:926310.011
acadlacyl-Coenzyme A dehydrogenase, long chain0.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PgkPhosphoglycerate kinase0.876
twstwins0.827
InRInsulin-like receptor0.704
EnoEnolase0.661
SdhBSuccinate dehydrogenase B0.581
CG3731CG3731 gene product from transcript CG3731-RA0.433
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.346
blwbellwether0.315
CG9140CG9140 gene product from transcript CG9140-RA0.312
GlyPGlycogen phosphorylase0.298
ATPsyn-gammaATP synthase-gamma chain0.291
CG1746CG1746 gene product from transcript CG1746-RA0.228
ND42NADH:ubiquinone reductase 42kD subunit precursor0.211
AtpalphaNa pump alpha subunit0.206
ThiolaseCG4581 gene product from transcript CG4581-RA0.199
CG10664CG10664 gene product from transcript CG10664-RB0.196
ND75NADH:ubiquinone reductase 75kD subunit precursor0.184
Pink1PTEN-induced putative kinase 10.184
AconAconitase0.176
parkparkin0.173
PyKPyruvate kinase0.170
TpiTriose phosphate isomerase0.155
l(1)G0156lethal (1) G01560.151
ScsalphaSuccinyl coenzyme A synthetase alpha subunit0.142
l(1)G0334lethal (1) G03340.129
MarfMitochondrial assembly regulatory factor0.125
CG4169CG4169 gene product from transcript CG4169-RA0.121
CG5028CG5028 gene product from transcript CG5028-RB0.104
ArgkArginine kinase0.096
PgiPhosphoglucose isomerase0.082
CG6439CG6439 gene product from transcript CG6439-RA0.080
Vap-33-1CG5014 gene product from transcript CG5014-RB0.080
hephemipterous0.076
walwalrus0.076
bskbasket0.076
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.074
CG9485CG9485 gene product from transcript CG9485-RD0.074
CG11876CG11876 gene product from transcript CG11876-RA0.072
panpangolin0.070
foxoforkhead box, sub-group O0.069
CG1347CG1347 gene product from transcript CG1347-RB0.068
CG7920CG7920 gene product from transcript CG7920-RA0.065
bratbrain tumor0.062
CG12203CG12203 gene product from transcript CG12203-RA0.061
S6kRPS6-p70-protein kinase0.061
ns3nucleostemin 30.061
ATPsyn-bATP synthase, subunit b0.057
CG5261CG5261 gene product from transcript CG5261-RB0.056
GpdhGlycerol 3 phosphate dehydrogenase0.055
porinCG6647 gene product from transcript CG6647-RA0.052
chercheerio0.051
ttm50tiny tim 500.050
CG3446CG3446 gene product from transcript CG3446-RA0.048
scylscylla0.047
Pk61CProtein kinase 61C0.047
RicRas which interacts with Calmodulin0.047
CG12079CG12079 gene product from transcript CG12079-RA0.047
Pglym78Phosphoglyceromutase0.046
seascheggia0.046
picpiccolo0.046
Sod2Superoxide dismutase 2 (Mn)0.045
CG5703CG5703 gene product from transcript CG5703-RA0.045
ThorCG8846 gene product from transcript CG8846-RA0.045
CG8818CG8818 gene product from transcript CG8818-RA0.044
AdhAlcohol dehydrogenase0.044
Pdp1PAR-domain protein 10.042
CG3683CG3683 gene product from transcript CG3683-RC0.042
dj-1betaCG1349 gene product from transcript CG1349-RA0.041
CG5362CG5362 gene product from transcript CG5362-RA0.041
GugGrunge0.041
Yp1Yolk protein 10.041
SdhCSuccinate dehydrogenase C0.040
cypecyclope0.039
OscpOligomycin sensitivity-conferring protein0.037
CG1640CG1640 gene product from transcript CG1640-RB0.036
Rac1CG2248 gene product from transcript CG2248-RA0.036
Src64BSrc oncogene at 64B0.035
Trxr-1Thioredoxin reductase-10.035
CG3321CG3321 gene product from transcript CG3321-RC0.035
Akt1CG4006 gene product from transcript CG4006-RA0.034
l(1)G0230lethal (1) G02300.033
opa1-likeoptic atrophy 1-like0.032
CG14235CG14235 gene product from transcript CG14235-RA0.032
CG12620CG12620 gene product from transcript CG12620-RA0.031
HcfHost cell factor0.031
CG9172CG9172 gene product from transcript CG9172-RA0.031
kuzkuzbanian0.030
l(3)03670lethal (3) 036700.030
Trf2TATA box binding protein-related factor 20.030
Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 20.030
Pp1alpha-96AProtein phosphatase 1alpha at 96A0.029
Rab5Rab-protein 50.028
Snap25Synapse protein 250.028
mtsmicrotubule star0.028
GstS1Glutathione S transferase S10.028
CG10277CG10277 gene product from transcript CG10277-RB0.027
chrbcharybde0.027
CatCatalase0.027
dmdiminutive0.027
CG4983CG4983 gene product from transcript CG4983-RA0.027
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
INSRinsulin receptor0.990
GPIglucose-6-phosphate isomerase0.971
ALDOAaldolase A, fructose-bisphosphate0.969
PGK1phosphoglycerate kinase 10.959
COX5Acytochrome c oxidase subunit Va0.953
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.950
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.949
UQCRC1ubiquinol-cytochrome c reductase core protein I0.949
TPI1triosephosphate isomerase 10.917
ENO1enolase 1, (alpha)0.899
PKM2pyruvate kinase, muscle0.846
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.802
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.794
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.780
UQCRC2ubiquinol-cytochrome c reductase core protein II0.759
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.753
ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)0.750
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.747
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.741
DLATdihydrolipoamide S-acetyltransferase0.689
HDAC3histone deacetylase 30.647
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.640
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.621
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.592
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.591
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.580
NDUFB5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa0.570
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.565
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.553
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.528
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.501
NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa0.491
NCOR1nuclear receptor corepressor 10.487
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.478
GRB10growth factor receptor-bound protein 100.471
HDAC4histone deacetylase 40.470
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.469
HIPK2homeodomain interacting protein kinase 20.460
NDUFA9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa0.447
LDHAlactate dehydrogenase A0.445
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.433
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.429
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.429
COX6Ccytochrome c oxidase subunit VIc0.419
MAPTmicrotubule-associated protein tau0.418
COX7Bcytochrome c oxidase subunit VIIb0.414
NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa0.408
IDH3Bisocitrate dehydrogenase 3 (NAD+) beta0.406
HDAC1histone deacetylase 10.398
NCF1neutrophil cytosolic factor 10.395
QARSglutaminyl-tRNA synthetase0.392
HK1hexokinase 10.380
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.379
MDM2Mdm2 p53 binding protein homolog (mouse)0.370
VDAC1voltage-dependent anion channel 10.364
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.357
IGF1Rinsulin-like growth factor 1 receptor0.357
IMMTinner membrane protein, mitochondrial0.346
HNF4Ahepatocyte nuclear factor 4, alpha0.344
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.342
CLN3ceroid-lipofuscinosis, neuronal 30.332
NDUFS7NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)0.328
EEF2eukaryotic translation elongation factor 20.325
CYC1cytochrome c-10.321
GOT2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.306
NUCB1nucleobindin 10.292
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.289
ESR1estrogen receptor 10.288
PARP1poly (ADP-ribose) polymerase 10.287
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.280
PFKLphosphofructokinase, liver0.279
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.276
HIGD2AHIG1 hypoxia inducible domain family, member 2A0.276
IRS1insulin receptor substrate 10.275
IDH3Gisocitrate dehydrogenase 3 (NAD+) gamma0.259
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.254
NCOA1nuclear receptor coactivator 10.251
RXRAretinoid X receptor, alpha0.240
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.237
COX4I1cytochrome c oxidase subunit IV isoform 10.232
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.232
OXA1Loxidase (cytochrome c) assembly 1-like0.227
ENO2enolase 2 (gamma, neuronal)0.225
DLDdihydrolipoamide dehydrogenase0.219
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.212
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.210
NCOR2nuclear receptor corepressor 20.206
CYCScytochrome c, somatic0.205
NOXA1NADPH oxidase activator 10.205
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.205
NDUFB1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa0.186
PPIDpeptidylprolyl isomerase D0.177
SIN3ASIN3 homolog A, transcription regulator (yeast)0.168
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.158
COX5Bcytochrome c oxidase subunit Vb0.151
PPARGperoxisome proliferator-activated receptor gamma0.148
ACO2aconitase 2, mitochondrial0.147
PDPK13-phosphoinositide dependent protein kinase-10.143
DCAF7DDB1 and CUL4 associated factor 70.138
IRS2insulin receptor substrate 20.137
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.994
Aldoaaldolase A, fructose-bisphosphate0.993
Ppargperoxisome proliferator activated receptor gamma0.990
Tpi1triosephosphate isomerase 10.984
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.984
Hbb-b1hemoglobin, beta adult major chain0.983
Suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.968
Insrinsulin receptor0.964
Thrathyroid hormone receptor alpha0.961
Leprleptin receptor0.961
Klklotho0.954
Pkm2pyruvate kinase, muscle0.943
Pnpla2patatin-like phospholipase domain containing 20.935
Aco2aconitase 2, mitochondrial0.931
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.927
Ndufa9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 90.926
Gm5506predicted gene 55060.914
Ldhalactate dehydrogenase A0.913
Gpi1glucose phosphate isomerase 10.911
Per1period homolog 1 (Drosophila)0.909
Drd2dopamine receptor D20.895
Stat5bsignal transducer and activator of transcription 5B0.893
Mef2dmyocyte enhancer factor 2D0.888
Fh1fumarate hydratase 10.886
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.861
Per2period homolog 2 (Drosophila)0.850
Ghrgrowth hormone receptor0.846
Esr2estrogen receptor 2 (beta)0.834
Pgam1phosphoglycerate mutase 10.826
Cyc1cytochrome c-10.819
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.810
Uqcrc2ubiquinol cytochrome c reductase core protein 20.810
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.785
Lef1lymphoid enhancer binding factor 10.784
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.778
Irs2insulin receptor substrate 20.768
Cycscytochrome c, somatic0.761
Ndufa5NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 50.745
Cdkn1bcyclin-dependent kinase inhibitor 1B0.744
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.741
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.731
2310061I04RikRIKEN cDNA 2310061I04 gene0.726
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.722
Pgk1phosphoglycerate kinase 10.720
Cav1caveolin 1, caveolae protein0.719
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.709
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.701
Igf1rinsulin-like growth factor I receptor0.688
Ndufb6NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 60.679
Cry2cryptochrome 2 (photolyase-like)0.674
Hif1ahypoxia inducible factor 1, alpha subunit0.667
Grb10growth factor receptor bound protein 100.659
Ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.650
Atf4activating transcription factor 40.640
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.634
Thrbthyroid hormone receptor beta0.622
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.614
Adrb1adrenergic receptor, beta 10.611
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.607
Ncoa1nuclear receptor coactivator 10.601
Agrpagouti related protein0.576
Mrpl12mitochondrial ribosomal protein L120.574
Ndufv2NADH dehydrogenase (ubiquinone) flavoprotein 20.564
Adra2cadrenergic receptor, alpha 2c0.559
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.532
Npc1Niemann Pick type C10.530
Otporthopedia homolog (Drosophila)0.527
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.526
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.519
LOC100048884novel member of the major urinary protein (Mup) gene family0.507
Trp53transformation related protein 530.494
Il5interleukin 50.479
Nfatc4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 40.478
Uqcrc1ubiquinol-cytochrome c reductase core protein 10.477
Tefthyrotroph embryonic factor0.470
Pax8paired box gene 80.469
Rbl2retinoblastoma-like 20.464
Smad3MAD homolog 3 (Drosophila)0.462
Stat5asignal transducer and activator of transcription 5A0.458
Rararetinoic acid receptor, alpha0.458
Ndufs3NADH dehydrogenase (ubiquinone) Fe-S protein 30.448
Samm50sorting and assembly machinery component 50 homolog (S. cerevisiae)0.442
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.442
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.441
Tcf7transcription factor 7, T-cell specific0.440
Sod2superoxide dismutase 2, mitochondrial0.440
Cscitrate synthase0.437
Mup19major urinary protein 190.437
Sstr4somatostatin receptor 40.433
Irf9interferon regulatory factor 90.432
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.427
Tyrtyrosinase0.421
Ncoa3nuclear receptor coactivator 30.420
Rdh10retinol dehydrogenase 10 (all-trans)0.404
Prkceprotein kinase C, epsilon0.402
Rad21RAD21 homolog (S. pombe)0.398
Prlrprolactin receptor0.397
Hdac2histone deacetylase 20.391
Sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.391
Vegfbvascular endothelial growth factor B0.385
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pkm2pyruvate kinase, muscle0.997
Tpi1triosephosphate isomerase 10.981
Pfkmphosphofructokinase, muscle0.961
Aldoaaldolase A, fructose-bisphosphate0.939
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.758
Gpiglucose phosphate isomerase0.754
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.750
Idh3Bisocitrate dehydrogenase 3 (NAD+) beta0.672
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.640
Fh1fumarate hydratase 10.568
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.555
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.544
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.522
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.516
Pdk2pyruvate dehydrogenase kinase, isozyme 20.503
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.472
Acat1acetyl-coenzyme A acetyltransferase 10.444
Vdac1voltage-dependent anion channel 10.437
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.392
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.375
Ola1Obg-like ATPase 10.346
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.314
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.309
Hspd1heat shock protein 1 (chaperonin)0.307
Etfdhelectron-transferring-flavoprotein dehydrogenase0.285
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.271
DbpD site of albumin promoter (albumin D-box) binding protein0.263
Ldhalactate dehydrogenase A0.263
Pfklphosphofructokinase, liver0.238
Ncanneurocan0.235
Adkadenosine kinase0.210
Aco2aconitase 2, mitochondrial0.207
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.196
Rab1bRAB1B, member RAS oncogene family0.193
Pygbphosphorylase, glycogen; brain0.193
Tecrtrans-2,3-enoyl-CoA reductase0.183
Mdh1malate dehydrogenase 1, NAD (soluble)0.183
Pebp1phosphatidylethanolamine binding protein 10.177
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.171
TufmTu translation elongation factor, mitochondrial0.160
Dlatdihydrolipoamide S-acetyltransferase0.152
Uqcrc2ubiquinol cytochrome c reductase core protein 20.150
Slc25a12solute carrier family 25 (mitochondrial carrier, Aralar), member 120.150
Aldh6a1aldehyde dehydrogenase 6 family, member A10.148
Pdhbpyruvate dehydrogenase (lipoamide) beta0.146
Slc25a11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.144
Atp6v0a1ATPase, H+ transporting, lysosomal V0 subunit A10.142
Vegfavascular endothelial growth factor A0.139
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.137
Apoa4apolipoprotein A-IV0.132
Suclg1succinate-CoA ligase, alpha subunit0.132
Pgm1phosphoglucomutase 10.132
Pfn1profilin 10.130
Gfm1G elongation factor, mitochondrial 10.128
Nr0b2nuclear receptor subfamily 0, group B, member 20.126
Stxbp1syntaxin binding protein 10.123
Ak1adenylate kinase 10.121
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.116
Nntnicotinamide nucleotide transhydrogenase0.103
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.103
Nr1d2nuclear receptor subfamily 1, group D, member 20.099
Prkcgprotein kinase C, gamma0.098
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.097
Bpnt13'(2'), 5'-bisphosphate nucleotidase 10.096
Pde4dipphosphodiesterase 4D interacting protein0.094
Ldhblactate dehydrogenase B0.094
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.093
Abp10annexin V-binding protein ABP-100.093
Akap1A kinase (PRKA) anchor protein 10.087
Guca2aguanylate cyclase activator 2a (guanylin)0.087
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.084
Got1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.083
Prdx3peroxiredoxin 30.083
Mrpl17mitochondrial ribosomal protein L170.083
Ghitmgrowth hormone inducible transmembrane protein0.082
RanRAN, member RAS oncogene family0.080
Cdh17cadherin 170.080
Pfkfb46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 40.078
Bcat1branched chain aminotransferase 1, cytosolic0.077
Admadrenomedullin0.077
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.076
Arandrogen receptor0.076
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.075
Stat6signal transducer and activator of transcription 60.074
Phkg1phosphorylase kinase, gamma 10.074
Rpl3lribosomal protein L3-like0.072
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.070
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.068
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.068
Col10a1collagen, type X, alpha 10.068
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.067
Coq6coenzyme Q6 homolog, monooxygenase (S. cerevisiae)0.067
Hibch3-hydroxyisobutyryl-Coenzyme A hydrolase0.066
Aldh7a1aldehyde dehydrogenase 7 family, member A10.065
Prkceprotein kinase C, epsilon0.064
Psme2proteasome (prosome, macropain) activator subunit 20.064
Idh3gisocitrate dehydrogenase 3 (NAD), gamma0.063
Prkcaprotein kinase C, alpha0.063
Acsl1acyl-CoA synthetase long-chain family member 10.063
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.062