The network for 'glycolytic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glycolytic process

The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to ethanol, lactate, or other small molecules, or fed into the TCA cycle.

NameDescriptionProbabilityFunc Analog Organism
ENO2Eno2p0.992
FBA1Fba1p0.982
GPM1Gpm1p0.981
PGK1Pgk1p0.969
ENO1Eno1p0.963
PGI1Pgi1p0.948
TDH3Tdh3p0.923
TPI1Tpi1p0.853
TDH2Tdh2p0.850
ADH1Adh1p0.777
TDH1Tdh1p0.642
CDC19Cdc19p0.613
PDC1Pdc1p0.569
ERR3Err3p0.217
EMI2Emi2p0.123
PFK1Pfk1p0.110
APA1Apa1p0.098
PFK2Pfk2p0.097
ERR2Err2p0.090
HXK2Hxk2p0.083
YLR177Whypothetical protein0.057
TIP1Tip1p0.053
HUG1Hug1p0.050
SAK1Sak1p0.049
GAL83Gal83p0.046
YGR017Whypothetical protein0.044
SUC2Suc2p0.043
YML053Chypothetical protein0.043
RHR2Rhr2p0.041
COX5BCox5bp0.041
OYE2Oye2p0.038
CUP1-1Cup1-1p0.030
GCR1Gcr1p0.029
GPT2Gpt2p0.028
CPD1Cpd1p0.028
SRD1Srd1p0.027
ERR1Err1p0.027
YPK3Ypk3p0.027
YOL014Whypothetical protein0.026
HOR7Hor7p0.025
YLR345Whypothetical protein0.023
ARP10Arp10p0.023
GLN1Gln1p0.023
SDS24Sds24p0.022
YOL013W-Ahypothetical protein0.022
YLR264C-Ahypothetical protein0.022
YLR162Whypothetical protein0.022
YDL124Whypothetical protein0.021
YEL023Chypothetical protein0.021
YMR122W-Ahypothetical protein0.021
LEU2Leu2p0.021
GPH1Gph1p0.021
CPR1Cpr1p0.021
HXT3Hxt3p0.021
HXK1Hxk1p0.020
MER1Mer1p0.020
URA3Ura3p0.020
APE3Ape3p0.020
GPD2Gpd2p0.020
FET4Fet4p0.020
SAP4Sap4p0.020
YOL038C-Ahypothetical protein0.019
SSA4Ssa4p0.019
HRK1Hrk1p0.019
HXT2Hxt2p0.019
MF(ALPHA)2Mf(alpha)2p0.019
YMR210Whypothetical protein0.018
TYE7Tye7p0.018
ZPS1Zps1p0.018
MF(ALPHA)1Mf(alpha)1p0.017
GLK1Glk1p0.017
RRT8Rrt8p0.017
SSA1Ssa1p0.017
GLC3Glc3p0.017
YGR205Whypothetical protein0.017
ATP6Atp6p0.017
SEN54Sen54p0.017
AUS1Aus1p0.016
PDC5Pdc5p0.016
AUA1Aua1p0.015
YNR014Whypothetical protein0.015
GDS1Gds1p0.015
WSC4Wsc4p0.015
HIT1Hit1p0.015
DIF1Dif1p0.015
YAR068Whypothetical protein0.015
YBR013Chypothetical protein0.015
SPL2Spl2p0.014
SWM2Swm2p0.014
HPF1Hpf1p0.014
DDR48Ddr48p0.014
LRO1Lro1p0.014
YOR390Whypothetical protein0.014
HSP33Hsp33p0.014
HXT4Hxt4p0.014
SWC7Swc7p0.014
ICS2Ics2p0.014
PTR2Ptr2p0.014
YPR157Whypothetical protein0.013
OPT2Opt2p0.013
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
EnoEnolase0.678
PgkPhosphoglycerate kinase0.310
ArgkArginine kinase0.121
Pglym78Phosphoglyceromutase0.120
PyKPyruvate kinase0.069
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.064
TpiTriose phosphate isomerase0.052
Tm2Tropomyosin 20.050
GlyPGlycogen phosphorylase0.049
PgiPhosphoglucose isomerase0.035
Mlc1Myosin alkali light chain 10.035
AdhAlcohol dehydrogenase0.034
scylscylla0.023
PgmPhosphogluconate mutase0.021
GpdhGlycerol 3 phosphate dehydrogenase0.018
Mlp84BMuscle LIM protein at 84B0.014
CG6904CG6904 gene product from transcript CG6904-RC0.014
Mp20Muscle protein 200.012
ImpL3Ecdysone-inducible gene L30.012
CG33936CG33936 gene product from transcript CG33936-RB0.011
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ALDOAaldolase A, fructose-bisphosphate1.000
TPI1triosephosphate isomerase 10.997
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.996
GPIglucose-6-phosphate isomerase0.990
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.982
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.982
PKM2pyruvate kinase, muscle0.979
LDHAlactate dehydrogenase A0.978
ENO1enolase 1, (alpha)0.978
PGK1phosphoglycerate kinase 10.973
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.970
NCOR2nuclear receptor corepressor 20.914
HNF4Ahepatocyte nuclear factor 4, alpha0.801
PGAM1phosphoglycerate mutase 1 (brain)0.761
NCOR1nuclear receptor corepressor 10.660
PPARAperoxisome proliferator-activated receptor alpha0.557
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.470
RARAretinoic acid receptor, alpha0.464
MEF2Amyocyte enhancer factor 2A0.207
NR2E3nuclear receptor subfamily 2, group E, member 30.173
PPARGperoxisome proliferator-activated receptor gamma0.165
ITGB1BP3integrin beta 1 binding protein 30.163
PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit0.136
RXRAretinoid X receptor, alpha0.130
MGEA5meningioma expressed antigen 5 (hyaluronidase)0.123
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.112
PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit0.099
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.094
SIN3ASIN3 homolog A, transcription regulator (yeast)0.094
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.093
GYS1glycogen synthase 1 (muscle)0.088
AGXT2alanine--glyoxylate aminotransferase 20.066
ESRRGestrogen-related receptor gamma0.062
EGFRepidermal growth factor receptor0.062
BBS1Bardet-Biedl syndrome 10.059
IGF1Rinsulin-like growth factor 1 receptor0.053
FBP2fructose-1,6-bisphosphatase 20.051
BCL6B-cell CLL/lymphoma 60.047
EP300E1A binding protein p3000.046
SP1Sp1 transcription factor0.045
HRhairless homolog (mouse)0.045
TKTtransketolase0.045
HK1hexokinase 10.043
NCOA1nuclear receptor coactivator 10.040
GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)0.040
JAK2Janus kinase 20.039
VEGFAvascular endothelial growth factor A0.036
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.035
GCKRglucokinase (hexokinase 4) regulator0.034
BHLHE40basic helix-loop-helix family, member e400.033
IGF2Rinsulin-like growth factor 2 receptor0.032
EGLN3egl nine homolog 3 (C. elegans)0.031
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.031
SLC16A3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.030
TUBA4Atubulin, alpha 4a0.030
HIPK2homeodomain interacting protein kinase 20.029
ALDOCaldolase C, fructose-bisphosphate0.029
HDAC3histone deacetylase 30.028
EGLN1egl nine homolog 1 (C. elegans)0.027
EPORerythropoietin receptor0.025
STAT5Asignal transducer and activator of transcription 5A0.024
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.024
BCAR1breast cancer anti-estrogen resistance 10.024
GHRgrowth hormone receptor0.024
NR1I2nuclear receptor subfamily 1, group I, member 20.024
PGRprogesterone receptor0.024
NTRK1neurotrophic tyrosine kinase, receptor, type 10.024
HDAC5histone deacetylase 50.023
NR0B2nuclear receptor subfamily 0, group B, member 20.022
IRS2insulin receptor substrate 20.022
PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.022
PGM1phosphoglucomutase 10.021
PRKAA2protein kinase, AMP-activated, alpha 2 catalytic subunit0.021
PFKLphosphofructokinase, liver0.021
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.020
PFKPphosphofructokinase, platelet0.020
ARandrogen receptor0.019
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.019
RUNX1runt-related transcription factor 10.018
CREBBPCREB binding protein0.018
GAPDHSglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.018
MECP2methyl CpG binding protein 2 (Rett syndrome)0.018
FAF1Fas (TNFRSF6) associated factor 10.018
CLEC4GC-type lectin domain family 4, member G0.018
MEF2Cmyocyte enhancer factor 2C0.017
IRS1insulin receptor substrate 10.017
INSRinsulin receptor0.016
ERO1LERO1-like (S. cerevisiae)0.015
MLXMAX-like protein X0.015
C16orf45chromosome 16 open reading frame 450.015
ABCG5ATP-binding cassette, sub-family G (WHITE), member 50.015
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 20.015
PTPN1protein tyrosine phosphatase, non-receptor type 10.014
ESR1estrogen receptor 10.014
STAT5Bsignal transducer and activator of transcription 5B0.014
CDHR5cadherin-related family member 50.014
PFKMphosphofructokinase, muscle0.014
BCKDKbranched chain ketoacid dehydrogenase kinase0.014
PGAM2phosphoglycerate mutase 2 (muscle)0.014
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.013
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Aldoaaldolase A, fructose-bisphosphate1.000
Pkm2pyruvate kinase, muscle1.000
Gpi1glucose phosphate isomerase 11.000
Ldhalactate dehydrogenase A0.999
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.999
Tpi1triosephosphate isomerase 10.999
Gm5506predicted gene 55060.996
Pgk1phosphoglycerate kinase 10.991
Leprleptin receptor0.989
Ppargperoxisome proliferator activated receptor gamma0.968
Pnpla2patatin-like phospholipase domain containing 20.964
Pfklphosphofructokinase, liver, B-type0.922
Stat5bsignal transducer and activator of transcription 5B0.896
Nr3c1nuclear receptor subfamily 3, group C, member 10.725
Mef2dmyocyte enhancer factor 2D0.703
Pgam1phosphoglycerate mutase 10.672
Irf9interferon regulatory factor 90.661
Ghrgrowth hormone receptor0.599
Stat3signal transducer and activator of transcription 30.590
Insrinsulin receptor0.573
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.497
Lepleptin0.389
Sim1single-minded homolog 1 (Drosophila)0.387
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.373
Stat5asignal transducer and activator of transcription 5A0.348
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.322
Hbb-b1hemoglobin, beta adult major chain0.300
Egln1EGL nine homolog 1 (C. elegans)0.286
Cav1caveolin 1, caveolae protein0.230
Aco2aconitase 2, mitochondrial0.198
Slc2a1solute carrier family 2 (facilitated glucose transporter), member 10.168
Thrathyroid hormone receptor alpha0.144
Foxo1forkhead box O10.143
Ncoa3nuclear receptor coactivator 30.139
Gcgrglucagon receptor0.134
Otporthopedia homolog (Drosophila)0.130
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.130
Gckglucokinase0.125
Klklotho0.115
Hnf4ahepatic nuclear factor 4, alpha0.115
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.109
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.102
Bhlhe40basic helix-loop-helix family, member e400.101
Adrb2adrenergic receptor, beta 20.101
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.096
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.093
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.086
Prlrprolactin receptor0.084
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.082
Bsgbasigin0.076
MaxMax protein0.073
Il4rainterleukin 4 receptor, alpha0.073
Adrb1adrenergic receptor, beta 10.071
Clcnkachloride channel Ka0.067
Il1r1interleukin 1 receptor, type I0.065
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.063
Pparaperoxisome proliferator activated receptor alpha0.063
Pygmmuscle glycogen phosphorylase0.063
Vhlvon Hippel-Lindau tumor suppressor0.062
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.060
Ppargc1bperoxisome proliferative activated receptor, gamma, coactivator 1 beta0.060
Foxp3forkhead box P30.060
Gys1glycogen synthase 1, muscle0.060
Apobapolipoprotein B0.060
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.059
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.058
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.058
Npy2rneuropeptide Y receptor Y20.057
Nos3nitric oxide synthase 3, endothelial cell0.056
Rdh10retinol dehydrogenase 10 (all-trans)0.055
Lhx6LIM homeobox protein 60.055
Esr2estrogen receptor 2 (beta)0.053
Arrdc3arrestin domain containing 30.053
Zfr2zinc finger RNA binding protein 20.052
Sstr4somatostatin receptor 40.052
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.052
Stat1signal transducer and activator of transcription 10.051
Cscitrate synthase0.051
Egln3EGL nine homolog 3 (C. elegans)0.051
Hdac4histone deacetylase 40.050
Stat2signal transducer and activator of transcription 20.050
Tattyrosine aminotransferase0.048
Vegfbvascular endothelial growth factor B0.048
Npy1rneuropeptide Y receptor Y10.045
Cnr1cannabinoid receptor 1 (brain)0.045
Nos1nitric oxide synthase 1, neuronal0.045
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.045
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.042
Ckmt2creatine kinase, mitochondrial 20.041
Zfp36zinc finger protein 360.041
Gja8gap junction protein, alpha 80.040
Il10interleukin 100.038
Lgals9lectin, galactose binding, soluble 90.038
Pfkpphosphofructokinase, platelet0.038
Ptpn11protein tyrosine phosphatase, non-receptor type 110.037
Arntaryl hydrocarbon receptor nuclear translocator0.037
Apoa1apolipoprotein A-I0.037
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.037
Chrm1cholinergic receptor, muscarinic 1, CNS0.036
Parp14poly (ADP-ribose) polymerase family, member 140.036
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pkm2pyruvate kinase, muscle0.929
Gpiglucose phosphate isomerase0.854
Aldoaaldolase A, fructose-bisphosphate0.828
Ldhalactate dehydrogenase A0.795
Tpi1triosephosphate isomerase 10.791
Pgam1phosphoglycerate mutase 1 (brain)0.599
Mifmacrophage migration inhibitory factor0.594
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.312
Eno1enolase 1, (alpha)0.274
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.091
Gipgastric inhibitory polypeptide0.077
Tpothyroid peroxidase0.074
Bcat1branched chain aminotransferase 1, cytosolic0.063
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.047
Stxbp1syntaxin binding protein 10.046
Tecrtrans-2,3-enoyl-CoA reductase0.041
Pgm1phosphoglucomutase 10.040
Wdfy1WD repeat and FYVE domain containing 10.037
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.033
Slc2a1solute carrier family 2 (facilitated glucose transporter), member 10.033
Zfp36zinc finger protein 360.031
Rab14RAB14, member RAS oncogene family0.028
Capns1calpain, small subunit 10.027
Ptpn12protein tyrosine phosphatase, non-receptor type 120.026
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.025
Phkg1phosphorylase kinase, gamma 10.023
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.023
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.021
Pygmphosphorylase, glycogen, muscle0.021
Bsgbasigin0.020
Litaflipopolysaccharide-induced TNF factor0.020
Tmem38atransmembrane protein 38a0.020
Prlrprolactin receptor0.019
Jak2Janus kinase 20.019
Sepw1selenoprotein W, 10.018
LOC100366119Mpv17 transgene, kidney disease mutant-like (predicted)-like0.017
RGD1564560similar to RCK0.017
Otcornithine carbamoyltransferase0.017
Hmox1heme oxygenase (decycling) 10.017
Nr1i2nuclear receptor subfamily 1, group I, member 20.017
Ptgs2prostaglandin-endoperoxide synthase 20.016
Lrrc8bleucine rich repeat containing 8 family, member B0.016
Rock2Rho-associated coiled-coil containing protein kinase 20.016
Rab3aRAB3A, member RAS oncogene family0.016
Gcgrglucagon receptor0.016
MaxMYC associated factor X0.015
Akap1A kinase (PRKA) anchor protein 10.015
Sgk2serum/glucocorticoid regulated kinase 20.014
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.014
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.014
Clip2CAP-GLY domain containing linker protein 20.014
Gstm1glutathione S-transferase mu 10.014
Fgf1fibroblast growth factor 10.014
B3galnt1beta-1,3-N-acetylgalactosaminyltransferase 10.014
Nr0b2nuclear receptor subfamily 0, group B, member 20.013
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.013
Rbm9RNA binding motif protein 90.013
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.013
Smpxsmall muscle protein, X-linked0.012
Pfkmphosphofructokinase, muscle0.012
Vdac1voltage-dependent anion channel 10.012
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.012
SnurfSNRPN upstream reading frame0.012
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.012
Ak1adenylate kinase 10.012
Cuzd1CUB and zona pellucida-like domains 10.012
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.011
Hnmthistamine N-methyltransferase0.011
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.011
Rpl3lribosomal protein L3-like0.011
Qprtquinolinate phosphoribosyltransferase0.011
Acy1aminoacylase 10.010
Vegfavascular endothelial growth factor A0.010
Aglamylo-1,6-glucosidase, 4-alpha-glucanotransferase0.010
LOC684425similar to Adenylosuccinate synthetase isozyme 1 (Adenylosuccinate synthetase, muscle isozyme) (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1)0.010
Leprleptin receptor0.010