The network for 'gluconeogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gluconeogenesis

The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

NameDescriptionProbabilityFunc Analog Organism
ENO1Eno1p0.990
TDH3Tdh3p0.987
VID30Vid30p0.982
GID7Gid7p0.968
FYV10Fyv10p0.946
FBA1Fba1p0.944
PGK1Pgk1p0.916
TDH1Tdh1p0.914
GID8Gid8p0.911
TDH2Tdh2p0.848
TPI1Tpi1p0.825
RMD5Rmd5p0.819
ENO2Eno2p0.763
GPM1Gpm1p0.705
ADH1Adh1p0.609
MOH1Moh1p0.575
VID24Vid24p0.452
MLS1Mls1p0.371
ERR3Err3p0.362
PYC2Pyc2p0.355
PYC1Pyc1p0.320
PDC1Pdc1p0.232
SIP4Sip4p0.216
PGI1Pgi1p0.204
VID28Vid28p0.203
HXK1Hxk1p0.187
TMA10Tma10p0.159
DOG2Dog2p0.145
MDH2Mdh2p0.122
SPO1Spo1p0.117
ERR2Err2p0.109
YAP6Yap6p0.096
NCE103Nce103p0.087
CDC19Cdc19p0.086
EMI2Emi2p0.080
PFK1Pfk1p0.078
HUG1Hug1p0.076
ADE12Ade12p0.067
BDH1Bdh1p0.064
WWM1Wwm1p0.062
GLN1Gln1p0.059
TRA1Tra1p0.057
CAR1Car1p0.056
SFC1Sfc1p0.055
NMT1Nmt1p0.049
REG1Reg1p0.048
UBP11Ubp11p0.048
ABM1Abm1p0.046
YDR186Chypothetical protein0.046
SSA4Ssa4p0.041
SSH4Ssh4p0.041
CUE5Cue5p0.040
CAT8Cat8p0.039
GTO3Gto3p0.039
SDS24Sds24p0.039
PDI1Pdi1p0.037
YMR210Whypothetical protein0.037
ERR1Err1p0.036
MAL32Mal32p0.036
SRD1Srd1p0.036
ERT1Ert1p0.035
YGR017Whypothetical protein0.035
TIP1Tip1p0.035
GAL83Gal83p0.033
OSH2Osh2p0.033
STP4Stp4p0.032
YMR122W-Ahypothetical protein0.032
YML053Chypothetical protein0.030
GPH1Gph1p0.030
COX13Cox13p0.029
GPM2Gpm2p0.029
YLR264C-Ahypothetical protein0.028
SUR1Sur1p0.028
YNR014Whypothetical protein0.028
CPD1Cpd1p0.027
CUP1-1Cup1-1p0.027
CIT2Cit2p0.027
SAK1Sak1p0.027
AGP2Agp2p0.027
HSP33Hsp33p0.026
LEU2Leu2p0.026
YLR162Whypothetical protein0.026
NCA3Nca3p0.025
OYE2Oye2p0.025
DBP1Dbp1p0.024
ARP10Arp10p0.024
AVT7Avt7p0.024
EMI5Emi5p0.024
COX5BCox5bp0.023
YOL014Whypothetical protein0.023
CTR3Ctr3p0.023
FMS1Fms1p0.023
YOL038C-Ahypothetical protein0.022
BNA5Bna5p0.022
PCL2Pcl2p0.022
SSO2Sso2p0.022
RSC8Rsc8p0.022
IDP3Idp3p0.022
URA3Ura3p0.021
HEF3Hef3p0.021
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
NCOA1nuclear receptor coactivator 10.300
CREBBPCREB binding protein0.214
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.105
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.090
ESR1estrogen receptor 10.087
ARandrogen receptor0.059
RXRAretinoid X receptor, alpha0.049
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.040
NCOR2nuclear receptor corepressor 20.027
TADA3transcriptional adaptor 30.023
DDIT3DNA-damage-inducible transcript 30.019
NCOA3nuclear receptor coactivator 30.016
PPP4R2protein phosphatase 4, regulatory subunit 20.016
NCOA2nuclear receptor coactivator 20.012
RARAretinoic acid receptor, alpha0.012
MED25mediator complex subunit 250.011
GHRgrowth hormone receptor0.011
KAT2BK(lysine) acetyltransferase 2B0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Per2period homolog 2 (Drosophila)0.993
Arntlaryl hydrocarbon receptor nuclear translocator-like0.992
Lepleptin0.992
Clockcircadian locomotor output cycles kaput0.988
Ppargperoxisome proliferator activated receptor gamma0.940
Cry2cryptochrome 2 (photolyase-like)0.936
Kiss1KiSS-1 metastasis-suppressor0.911
Insrinsulin receptor0.909
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.876
Leprleptin receptor0.870
Ren1renin 1 structural0.728
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.686
Irs2insulin receptor substrate 20.665
Cdkn1bcyclin-dependent kinase inhibitor 1B0.616
Mup10major urinary protein 100.609
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.576
Prlrprolactin receptor0.564
Per1period homolog 1 (Drosophila)0.548
Cry1cryptochrome 1 (photolyase-like)0.511
LOC100048884novel member of the major urinary protein (Mup) gene family0.506
Mup19major urinary protein 190.499
JunJun oncogene0.488
Cideccell death-inducing DFFA-like effector c0.482
Tgfb1transforming growth factor, beta 10.449
Plin1perilipin 10.409
Spry4sprouty homolog 4 (Drosophila)0.385
Thrspthyroid hormone responsive SPOT14 homolog (Rattus)0.376
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.376
Esr1estrogen receptor 1 (alpha)0.353
Clk1CDC-like kinase 10.336
Gm5506predicted gene 55060.335
Nr1h4nuclear receptor subfamily 1, group H, member 40.303
Pgam1phosphoglycerate mutase 10.295
Clk4CDC like kinase 40.284
Trib3tribbles homolog 3 (Drosophila)0.283
Lef1lymphoid enhancer binding factor 10.243
Nos1nitric oxide synthase 1, neuronal0.240
Agtr1aangiotensin II receptor, type 1a0.240
Mup5major urinary protein 50.230
Mup1major urinary protein 10.216
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.215
Stat5asignal transducer and activator of transcription 5A0.206
Fgafibrinogen alpha chain0.202
Mup3major urinary protein 30.202
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.192
Usp2ubiquitin specific peptidase 20.191
Tcf7transcription factor 7, T-cell specific0.189
Cps1carbamoyl-phosphate synthetase 10.184
Ccnl2cyclin L20.175
Mup9major urinary protein 90.172
Pnpla2patatin-like phospholipase domain containing 20.172
Egr1early growth response 10.170
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.166
Mup12major urinary protein 120.162
FosFBJ osteosarcoma oncogene0.146
Mup4major urinary protein 40.141
Mup15major urinary protein 150.138
Mup13major urinary protein 130.135
Mup8major urinary protein 80.135
Mup14major urinary protein 140.133
Cfdcomplement factor D (adipsin)0.130
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.127
Ulk1Unc-51 like kinase 1 (C. elegans)0.125
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.125
LOC100048885major urinary protein LOC1000488850.122
Ahsgalpha-2-HS-glycoprotein0.121
Ldhalactate dehydrogenase A0.120
Mup17major urinary protein 170.119
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.111
Rbl2retinoblastoma-like 20.109
Dmgdhdimethylglycine dehydrogenase precursor0.109
Mup11major urinary protein 110.108
Vdrvitamin D receptor0.106
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.105
Kdm3alysine (K)-specific demethylase 3A0.104
Hif1ahypoxia inducible factor 1, alpha subunit0.104
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.100
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 20.100
Mup7major urinary protein 70.097
Fabp1fatty acid binding protein 1, liver0.093
Hamphepcidin antimicrobial peptide0.090
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.089
Tefthyrotroph embryonic factor0.087
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.087
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.087
Arandrogen receptor0.086
Nfil3nuclear factor, interleukin 3, regulated0.083
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.082
Mup2major urinary protein 20.082
Pgk1phosphoglycerate kinase 10.077
Fbxl3F-box and leucine-rich repeat protein 30.077
Cav1caveolin 1, caveolae protein0.075
Lipelipase, hormone sensitive0.071
Hrghistidine-rich glycoprotein0.070
Pou3f1POU domain, class 3, transcription factor 10.070
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.069
Apoc4apolipoprotein C-IV0.068
Akr1c6aldo-keto reductase family 1, member C60.068
Thrathyroid hormone receptor alpha0.067
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.065
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Aldoaaldolase A, fructose-bisphosphate0.974
Ldhalactate dehydrogenase A0.733
Tpi1triosephosphate isomerase 10.583
DbpD site of albumin promoter (albumin D-box) binding protein0.532
Pkm2pyruvate kinase, muscle0.412
Eno1enolase 1, (alpha)0.299
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.228
Pgk1phosphoglycerate kinase 10.141
Nr1d2nuclear receptor subfamily 1, group D, member 20.093
Cox8bcytochrome c oxidase, subunit VIIIb0.071
PVRpoliovirus receptor0.060
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.051
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.049
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.046
Gpiglucose phosphate isomerase0.044
Etfdhelectron-transferring-flavoprotein dehydrogenase0.039
Slc37a4solute carrier family 37 (glucose-6-phosphate transporter), member 40.038
Acsl1acyl-CoA synthetase long-chain family member 10.037
Dusp1dual specificity phosphatase 10.036
Nxf1nuclear RNA export factor 10.035
Grinl1aglutamate receptor, ionotropic, N-methyl D-aspartate-like 1A0.030
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.028
Pxmp2peroxisomal membrane protein 20.025
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.025
Ass1argininosuccinate synthetase 10.025
Irf3interferon regulatory factor 30.022
Ak1adenylate kinase 10.022
Acacbacetyl-Coenzyme A carboxylase beta0.021
FosFBJ osteosarcoma oncogene0.020
Pgam1phosphoglycerate mutase 1 (brain)0.020
Fbp1fructose-1,6-bisphosphatase 10.018
Nfibnuclear factor I/B0.018
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.018
Myh1myosin, heavy polypeptide 1, skeletal muscle, adult0.018
Pfkmphosphofructokinase, muscle0.017
Gstm2glutathione S-transferase mu 20.017
Zbtb20zinc finger and BTB domain containing 200.016
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.015
Casp2caspase 20.014
Klf4Kruppel-like factor 4 (gut)0.014
Btg2BTG family, member 20.013
Mstnmyostatin0.013
Nfianuclear factor I/A0.012
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.012
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.012
Slc22a1solute carrier family 22 (organic cation transporter), member 10.012
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.011
LOC100361864UDP-glucuronosyltransferase 2B3-like0.011
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.011
Ndrg2N-myc downstream regulated gene 20.011
G6pcglucose-6-phosphatase, catalytic subunit0.011
RGD1305347similar to RIKEN cDNA 2610528J110.011
Rararetinoic acid receptor, alpha0.011
KitlgKIT ligand0.011
A1cfAPOBEC1 complementation factor0.011
Tattyrosine aminotransferase0.011
Dio1deiodinase, iodothyronine, type I0.011
Slc25a10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 100.011
LOC100366119Mpv17 transgene, kidney disease mutant-like (predicted)-like0.011
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.010
Rxrgretinoid X receptor gamma0.010
Acot12acyl-CoA thioesterase 120.010