The network for 'regulation of mitotic spindle organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mitotic spindle organization

Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.

NameDescriptionProbabilityFunc Analog Organism
CLB1Clb1p0.092
CLB4Clb4p0.087
NDD1Ndd1p0.056
CKS1Cks1p0.056
CLB3Clb3p0.055
VIK1Vik1p0.043
KAR9Kar9p0.043
CDC6Cdc6p0.041
CLN1Cln1p0.037
KAR3Kar3p0.037
CDC28Cdc28p0.033
CLB5Clb5p0.030
DYN1Dyn1p0.026
STU1Stu1p0.025
MSA2Msa2p0.025
KIP1Kip1p0.022
KIP2Kip2p0.020
DAM1Dam1p0.020
STB1Stb1p0.020
STU2Stu2p0.019
DYN3Dyn3p0.018
PTI1Pti1p0.018
ACM1Acm1p0.018
CDC20Cdc20p0.017
ARP10Arp10p0.016
SPC97Spc97p0.015
SHE1She1p0.014
SLK19Slk19p0.014
SLI15Sli15p0.014
SRD1Srd1p0.014
CIN8Cin8p0.014
TOF2Tof2p0.014
YLR162Whypothetical protein0.013
YAR068Whypothetical protein0.013
YLR264C-Ahypothetical protein0.013
LEU2Leu2p0.013
MTW1Mtw1p0.012
YOL038C-Ahypothetical protein0.012
MER1Mer1p0.011
HST3Hst3p0.011
SPS4Sps4p0.011
PDS1Pds1p0.011
SIC1Sic1p0.011
YPR157Whypothetical protein0.011
OKP1Okp1p0.011
ASE1Ase1p0.010
HXT3Hxt3p0.010
SPL2Spl2p0.010
CLB6Clb6p0.010
NBL1Nbl1p0.010
YAR066Whypothetical protein0.010
ATP6Atp6p0.010
NUP157Nup157p0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
fzy-1Protein FZY-10.394
hcp-2Protein HCP-20.358
clec-87Protein CLEC-870.338
cyb-1Protein CYB-10.302
cdc-37Protein CDC-370.301
cyb-2.1Protein CYB-2.10.297
gpr-1Protein GPR-10.277
cyb-3Protein CYB-30.270
cin-4Protein CIN-40.245
gpr-2Protein GPR-20.234
spdl-1Protein SPDL-10.232
nasp-2Protein NASP-20.225
F09G2.8Protein F09G2.80.196
cyb-2.2Protein CYB-2.20.194
mcm-7Protein MCM-70.186
cpg-2Protein CPG-20.176
puf-6Protein PUF-60.174
air-1Protein AIR-10.172
rsa-1Protein RSA-10.144
rod-1Protein ROD-10.124
pcn-1Protein PCN-10.116
clec-88Protein CLEC-880.114
hcp-1Protein HCP-10.108
zif-1Protein ZIF-10.100
F18A1.7Protein F18A1.70.100
rnr-1Protein RNR-10.098
klp-19Protein KLP-190.095
mcm-3Protein MCM-30.094
CELE_Y43F11A.1Protein Y43F11A.10.092
scc-1Protein SCC-10.089
gln-6Protein GLN-60.085
puf-7Protein PUF-70.079
air-2Protein AIR-20.077
T19H12.2Protein T19H12.20.076
fbxa-215Protein FBXA-2150.075
mep-1Protein MEP-10.057
dao-5Protein DAO-50.056
cye-1Protein CYE-10.056
gpd-4Protein GPD-40.055
mcm-6Protein MCM-60.051
aspm-1Protein ASPM-10.050
knl-1Protein KNL-10.048
bub-1Protein BUB-10.046
cpg-1Protein CPG-10.046
C01H6.9Protein C01H6.90.042
cec-5Protein CEC-50.042
bath-42Protein BATH-420.041
mcm-5Protein MCM-50.040
hcp-6Protein HCP-60.038
asfl-1Protein ASFL-10.037
lst-3Protein LST-30.036
inft-2Protein INFT-20.033
CELE_Y14H12B.2Protein Y14H12B.20.033
F07A11.2Protein F07A11.20.033
bmk-1Protein BMK-10.033
klp-16Protein KLP-160.032
clec-91Protein CLEC-910.031
F33H2.3Protein F33H2.30.031
cdk-1Protein CDK-10.031
mex-6Protein MEX-60.031
his-68Protein HIS-680.030
cpg-3Protein CPG-30.029
agl-1Protein AGL-10.029
retr-1Protein RETR-10.028
rpa-2Protein RPA-20.028
ect-2Protein ECT-20.027
dsh-2Protein DSH-20.026
spn-4Protein SPN-40.026
egg-3Protein EGG-30.026
cki-2Protein CKI-20.025
hcp-4Protein HCP-40.023
prp-8Protein PRP-80.023
top-2Protein TOP-20.023
klp-4Protein KLP-40.022
math-33Protein MATH-330.022
T07C4.10Protein T07C4.100.022
cyk-4Protein CYK-40.022
T16G12.4Protein T16G12.40.022
ZK507.6Protein ZK507.60.022
C05C10.5Protein C05C10.50.021
orc-5Protein ORC-50.021
xnp-1Protein XNP-10.020
C44B9.3Protein C44B9.30.020
oma-1Protein OMA-10.020
CELE_C27A7.6Protein C27A7.60.019
tbb-2Protein TBB-20.019
R05D3.2Protein R05D3.20.017
CELE_T16H12.11Protein T16H12.110.017
hil-5Protein HIL-50.016
ucr-2.3Protein UCR-2.30.016
icp-1Protein ICP-10.016
wago-1Protein WAGO-10.016
CELE_T03F6.3Protein T03F6.30.016
gna-2Protein GNA-20.015
sac-1Protein SAC-10.015
cul-1Protein CUL-10.015
csc-1Protein CSC-10.015
mex-5Protein MEX-50.015
Y62E10A.17Protein Y62E10A.170.015
unc-80Protein UNC-800.015
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ncdnon-claret disjunctional0.957
cmetCENP-meta0.777
aspabnormal spindle0.746
Klp61FKinesin-like protein at 61F0.743
BubR1Bub1-related kinase0.718
IncenpInner centromere protein0.661
aslasterless0.655
CycB3Cyclin B30.654
pavpavarotti0.596
gwlgreatwall0.474
poloCG12306 gene product from transcript CG12306-RA0.461
CycBCyclin B0.427
dupdouble parked0.357
Klp67AKinesin-like protein at 67A0.264
dpadisc proliferation abnormal0.255
Cenp-CCG31258 gene product from transcript CG31258-RA0.243
ballballchen0.217
marsCG17064 gene product from transcript CG17064-RB0.208
Orc2Origin recognition complex subunit 20.187
Klp3AKinesin-like protein at 3A0.167
Spc105RSpc105-related0.162
Orc5Origin recognition complex subunit 50.134
Klp10ACG1453 gene product from transcript CG1453-RA0.126
barrbarren0.120
SMC2CG10212 gene product from transcript CG10212-RA0.118
spd-2spindle defective 20.091
nebnebbish0.079
scrascraps0.073
Cks30ACyclin-dependent kinase subunit 30A0.073
Ndc80CG9938 gene product from transcript CG9938-RA0.058
fzyfizzy0.058
tumtumbleweed0.058
Nek2CG17256 gene product from transcript CG17256-RA0.057
twetwine0.052
Cdc27CG8610 gene product from transcript CG8610-RA0.052
pimpimples0.050
mus209mutagen-sensitive 2090.047
CycACyclin A0.046
Cap-GCG34438 gene product from transcript CG34438-RF0.043
thrthree rows0.043
rodrough deal0.039
stgstring0.037
ana3anastral spindle 30.033
stisticky0.031
lkb1CG9374 gene product from transcript CG9374-RJ0.029
cidcentromere identifier0.029
CG8478CG8478 gene product from transcript CG8478-RD0.027
feofascetto0.027
Mcm2Minichromosome maintenance 20.026
Spc25CG7242 gene product from transcript CG7242-RA0.025
vtdverthandi0.025
SseSeparase0.024
cnncentrosomin0.023
Poc1Proteome of centrioles 10.023
nodno distributive disjunction0.023
Nuf2CG8902 gene product from transcript CG8902-RA0.021
mei-S332meiotic from via Salaria 3320.021
Grip71CG10346 gene product from transcript CG10346-RA0.019
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.019
Top1Topoisomerase 10.019
Cdc37CG12019 gene product from transcript CG12019-RA0.018
Sas-4CG10061 gene product from transcript CG10061-RA0.018
mus304mutagen-sensitive 3040.017
CG4680CG4680 gene product from transcript CG4680-RA0.015
CG11120CG11120 gene product from transcript CG11120-RA0.015
ana2anastral spindle 20.014
larpLa related protein0.014
cavcaravaggio0.013
pblpebble0.012
gammaTub37Cgamma-Tubulin at 37C0.012
Grip75CG6176 gene product from transcript CG6176-RA0.011
pcmpacman0.011
wispwispy0.011
Mcm5Minichromosome maintenance 50.010
MybMyb oncogene-like0.010
DNApol-alpha60DNA polymerase alpha 60kD0.010
subsubito0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDK2cyclin-dependent kinase 20.702
PRC1protein regulator of cytokinesis 10.657
CCNB2cyclin B20.647
CCNA2cyclin A20.618
AURKAaurora kinase A0.412
CDK1cyclin-dependent kinase 10.369
CKS1BCDC28 protein kinase regulatory subunit 1B0.349
CCNB1cyclin B10.331
KIF20Akinesin family member 20A0.248
CKS2CDC28 protein kinase regulatory subunit 20.231
CKAP5cytoskeleton associated protein 50.223
FOXM1forkhead box M10.164
TTKTTK protein kinase0.150
CDKN3cyclin-dependent kinase inhibitor 30.127
RACGAP1Rac GTPase activating protein 10.125
TOP1topoisomerase (DNA) I0.093
CDC20cell division cycle 20 homolog (S. cerevisiae)0.084
GPSM2G-protein signaling modulator 20.074
PKD2polycystic kidney disease 2 (autosomal dominant)0.055
CENPEcentromere protein E, 312kDa0.047
KIF1Bkinesin family member 1B0.043
KIF4Akinesin family member 4A0.038
KIF23kinesin family member 230.032
NCAPGnon-SMC condensin I complex, subunit G0.032
CDCA3cell division cycle associated 30.031
SPAG5sperm associated antigen 50.030
SKP2S-phase kinase-associated protein 2 (p45)0.028
NCAPD2non-SMC condensin I complex, subunit D20.026
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.026
PTTG1pituitary tumor-transforming 10.026
PSRC1proline/serine-rich coiled-coil 10.019
ANKRD17ankyrin repeat domain 170.018
FBXO5F-box protein 50.018
CCNE1cyclin E10.018
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.017
SMC4structural maintenance of chromosomes 40.016
NUSAP1nucleolar and spindle associated protein 10.014
RRM1ribonucleotide reductase M10.014
C12orf48chromosome 12 open reading frame 480.014
CENPFcentromere protein F, 350/400kDa (mitosin)0.014
NCAPG2non-SMC condensin II complex, subunit G20.012
TOP2Atopoisomerase (DNA) II alpha 170kDa0.012
FKBP3FK506 binding protein 3, 25kDa0.012
TRIP13thyroid hormone receptor interactor 130.012
KIF2Ckinesin family member 2C0.012
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.011
HMMRhyaluronan-mediated motility receptor (RHAMM)0.011
CHEK2CHK2 checkpoint homolog (S. pombe)0.011
NEK2NIMA (never in mitosis gene a)-related kinase 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdk1cyclin-dependent kinase 10.965
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.915
Prc1protein regulator of cytokinesis 10.910
Ccnb2cyclin B20.884
Ccnb1cyclin B10.877
Ccna2cyclin A20.868
Kif20akinesin family member 20A0.841
Hmmrhyaluronan mediated motility receptor (RHAMM)0.660
Ckap2cytoskeleton associated protein 20.586
Plk1polo-like kinase 1 (Drosophila)0.524
Kif22kinesin family member 220.344
Birc5baculoviral IAP repeat-containing 50.328
H2afxH2A histone family, member X0.300
Top2atopoisomerase (DNA) II alpha0.252
Racgap1Rac GTPase-activating protein 10.231
Pkd2polycystic kidney disease 20.199
Kif2ckinesin family member 2C0.188
Aurkbaurora kinase B0.178
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.173
Dlgap5discs, large (Drosophila) homolog-associated protein 50.165
Ube2cubiquitin-conjugating enzyme E2C0.152
Ncaphnon-SMC condensin I complex, subunit H0.144
Cdc25ccell division cycle 25 homolog C (S. pombe)0.138
Kif4kinesin family member 40.131
Cdca8cell division cycle associated 80.124
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.106
Foxm1forkhead box M10.091
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.090
Gtse1G two S phase expressed protein 10.079
Cys1cystin 10.056
Megf8multiple EGF-like-domains 80.052
Kif11kinesin family member 110.052
Spag5sperm associated antigen 50.047
Ccnfcyclin F0.045
Bicc1bicaudal C homolog 1 (Drosophila)0.044
Cenpacentromere protein A0.042
Aurkaaurora kinase A0.041
Lmnb1lamin B10.040
Anlnanillin, actin binding protein0.039
Ccdc99coiled-coil domain containing 990.039
Cdca5cell division cycle associated 50.037
Kif23kinesin family member 230.037
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.035
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.034
PbkPDZ binding kinase0.032
Iqgap3IQ motif containing GTPase activating protein 30.032
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.029
Meox2mesenchyme homeobox 20.025
Ift140intraflagellar transport 140 homolog (Chlamydomonas)0.025
Fbn1fibrillin 10.024
Mis18bp1MIS18 binding protein 10.024
Incenpinner centromere protein0.023
Macf1microtubule-actin crosslinking factor 10.023
Cks2CDC28 protein kinase regulatory subunit 20.022
Notch2Notch gene homolog 2 (Drosophila)0.021
Tk1thymidine kinase 10.021
Tcf19transcription factor 190.020
Cenpncentromere protein N0.020
TtkTtk protein kinase0.019
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.018
Nusap1nucleolar and spindle associated protein 10.018
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.018
Il6stinterleukin 6 signal transducer0.017
Cdkn3cyclin-dependent kinase inhibitor 30.016
Cenpmcentromere protein M0.016
Cdkn1bcyclin-dependent kinase inhibitor 1B0.015
Fam64afamily with sequence similarity 64, member A0.015
Itgb1integrin beta 1 (fibronectin receptor beta)0.015
Mki67antigen identified by monoclonal antibody Ki 670.015
Arhgef1Rho guanine nucleotide exchange factor (GEF) 10.014
Eme1essential meiotic endonuclease 1 homolog 1 (S. pombe)0.013
Tmem217transmembrane protein 2170.013
Gsg2germ cell-specific gene 20.012
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.012
Rad51ap1RAD51 associated protein 10.012
Ube2tubiquitin-conjugating enzyme E2T (putative)0.012
Slc25a2solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 20.011
Tacc3transforming, acidic coiled-coil containing protein 30.011
Plk4polo-like kinase 4 (Drosophila)0.011
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.011
Dennd5aDENN/MADD domain containing 5A0.011
2810417H13RikRIKEN cDNA 2810417H13 gene0.011
Rad51cRAD51 homolog c (S. cerevisiae)0.011
Rb1retinoblastoma 10.011
Fam83dfamily with sequence similarity 83, member D0.010
Cenpfcentromere protein F0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism