The network for 'histone h3 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h3 acetylation

The modification of histone H3 by the addition of an acetyl group.

Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TRA1Tra1p0.950
TAF6Taf6p0.787
NGG1Ngg1p0.734
ADA2Ada2p0.650
SPT7Spt7p0.550
SUS1Sus1p0.358
SPT8Spt8p0.302
TAF5Taf5p0.297
SPT20Spt20p0.216
HHT1Hht1p0.212
TAF10Taf10p0.190
SGF73Sgf73p0.183
HFI1Hfi1p0.150
TAF12Taf12p0.085
UBP8Ubp8p0.051
SGF11Sgf11p0.037
RCO1Rco1p0.033
SGF29Sgf29p0.033
SWI1Swi1p0.030
IKI1Iki1p0.030
MOT1Mot1p0.029
SNF5Snf5p0.028
EPL1Epl1p0.028
ELP4Elp4p0.022
TAF9Taf9p0.020
POL2Pol2p0.020
ELP6Elp6p0.019
BDF1Bdf1p0.018
HDA2Hda2p0.016
YNG1Yng1p0.016
GCN5Gcn5p0.015
EAF1Eaf1p0.014
RSC4Rsc4p0.012
SPT3Spt3p0.012
ISW1Isw1p0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
thoc-3Protein THOC-30.022
tag-298Protein TAG-2980.017
apr-1Protein APR-10.017
tbck-1Protein TBCK-10.017
mtk-1Protein MTK-10.016
lin-37Protein LIN-370.015
hda-2Protein HDA-20.015
unc-40Protein UNC-400.014
vab-1Protein VAB-10.014
sdc-1Protein SDC-10.014
cdk-8Protein CDK-80.013
CELE_F01D4.5Protein F01D4.50.013
sys-1Protein SYS-10.012
cids-2Protein CIDS-20.012
ocrl-1Protein OCRL-10.012
rbr-2Protein RBR-20.011
efa-6Protein EFA-60.011
lin-24Protein LIN-240.010
sec-5Protein SEC-50.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PcafCG4107 gene product from transcript CG4107-RA0.990
CG10414CG10414 gene product from transcript CG10414-RA0.986
dikdiskette0.862
HcfHost cell factor0.718
D12CG13400 gene product from transcript CG13400-RA0.714
Atac1ATAC component 10.710
Mocs2Molybdopterin synthase 20.437
Chrac-14CG13399 gene product from transcript CG13399-RA0.382
mod(mdg4)modifier of mdg40.373
Sgf29CG30390 gene product from transcript CG30390-RA0.285
hephemipterous0.215
notnon-stop0.197
Nipped-ACG33554 gene product from transcript CG33554-RE0.158
Saf6SAGA factor-like TAF60.155
pr-set7CG3307 gene product from transcript CG3307-RC0.119
ash1absent, small, or homeotic discs 10.119
CG10435CG10435 gene product from transcript CG10435-RA0.073
cgcombgap0.072
domedomeless0.071
eggeggless0.067
ebiCG4063 gene product from transcript CG4063-RA0.059
wdswill die slowly0.051
Ada2bCG9638 gene product from transcript CG9638-RA0.051
wdewindei0.050
Rpb4CG33520 gene product from transcript CG33520-RF0.049
Jarid2CG3654 gene product from transcript CG3654-RD0.044
Taf1TBP-associated factor 10.041
NC2betaCG4185 gene product from transcript CG4185-RA0.039
B52CG10851 gene product from transcript CG10851-RB0.037
mldmolting defective0.033
BRWD3CG31132 gene product from transcript CG31132-RA0.028
ash2absent, small, or homeotic discs 20.027
CTCFCG8591 gene product from transcript CG8591-RA0.024
Sgf11CG13379 gene product from transcript CG13379-RB0.023
His2AvHistone H2A variant0.023
CG14005CG14005 gene product from transcript CG14005-RA0.023
Spt3CG3169 gene product from transcript CG3169-RA0.019
e(y)3enhancer of yellow 30.019
Chrac-16CG15736 gene product from transcript CG15736-RA0.019
TbpTATA binding protein0.018
Mes2CG11100 gene product from transcript CG11100-RB0.018
InRInsulin-like receptor0.018
snostrawberry notch0.018
Trf2TATA box binding protein-related factor 20.018
RpII215RNA polymerase II 215kD subunit0.017
msl-3male-specific lethal 30.017
lidlittle imaginal discs0.017
Su(fu)Suppressor of fused0.017
CG5591CG5591 gene product from transcript CG5591-RA0.016
ushu-shaped0.015
Hr39Hormone receptor-like in 390.015
ykiyorkie0.014
fs(2)ltoPP43female sterile (2) ltoPP430.014
pallpallbearer0.014
dosdaughter of sevenless0.013
Taf2TBP-associated factor 20.013
Taf6TBP-associated factor 60.013
fs(1)hfemale sterile (1) homeotic0.013
Tao-1CG14217 gene product from transcript CG14217-RF0.013
CG9339CG9339 gene product from transcript CG9339-RG0.012
miminus0.012
CG7183CG7183 gene product from transcript CG7183-RA0.012
Sir2CG5216 gene product from transcript CG5216-RA0.012
SuURSuppressor of Under-Replication0.012
dcodiscs overgrown0.011
CG6506CG6506 gene product from transcript CG6506-RA0.011
MED16Mediator complex subunit 160.011
rdxroadkill0.011
CG3065CG3065 gene product from transcript CG3065-RA0.011
rolsrolling pebbles0.011
TfIIA-LTranscription factor IIA L0.011
CG32343CG32343 gene product from transcript CG32343-RB0.011
JraJun-related antigen0.010
dadaughterless0.010
CG5986CG5986 gene product from transcript CG5986-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa1.000
USP22ubiquitin specific peptidase 221.000
WDR5WD repeat domain 51.000
TBPTATA box binding protein1.000
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)1.000
KAT2AK(lysine) acetyltransferase 2A1.000
TRRAPtransformation/transcription domain-associated protein0.999
TADA3transcriptional adaptor 30.999
CREBBPCREB binding protein0.998
IKBKAPinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein0.997
KAT2BK(lysine) acetyltransferase 2B0.989
ELP2elongation protein 2 homolog (S. cerevisiae)0.980
MBIPMAP3K12 binding inhibitory protein 10.980
CHEK2CHK2 checkpoint homolog (S. pombe)0.963
ELP3elongation protein 3 homolog (S. cerevisiae)0.953
EP300E1A binding protein p3000.950
SMURF1SMAD specific E3 ubiquitin protein ligase 10.912
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.906
CCDC101coiled-coil domain containing 1010.904
ELP4elongation protein 4 homolog (S. cerevisiae)0.892
PAXIP1PAX interacting (with transcription-activation domain) protein 10.880
TAF10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa0.847
SUPT3Hsuppressor of Ty 3 homolog (S. cerevisiae)0.815
MEN1multiple endocrine neoplasia I0.807
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.751
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa0.731
RBBP5retinoblastoma binding protein 50.715
HIST2H3Chistone cluster 2, H3c0.706
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.698
TP53tumor protein p530.696
TAF1CTATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa0.666
SIN3ASIN3 homolog A, transcription regulator (yeast)0.645
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.629
HCFC1host cell factor C1 (VP16-accessory protein)0.611
ARID1AAT rich interactive domain 1A (SWI-like)0.604
MYST1MYST histone acetyltransferase 10.602
CDK9cyclin-dependent kinase 90.601
TAF3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa0.575
TAF1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa0.572
PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 20.561
MECP2methyl CpG binding protein 2 (Rett syndrome)0.535
TAL1T-cell acute lymphocytic leukemia 10.523
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa0.516
ARID1BAT rich interactive domain 1B (SWI1-like)0.515
SETD7SET domain containing (lysine methyltransferase) 70.505
SIRT1sirtuin 10.502
HTThuntingtin0.468
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.463
AFF1AF4/FMR2 family, member 10.455
HIPK2homeodomain interacting protein kinase 20.433
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.422
HDAC1histone deacetylase 10.413
PPFIA1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 10.393
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.372
ATXN7ataxin 70.371
TADA2Atranscriptional adaptor 2A0.359
WWOXWW domain containing oxidoreductase0.343
ARandrogen receptor0.294
UBE3Aubiquitin protein ligase E3A0.292
LMO4LIM domain only 40.284
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.260
HIST1H3Bhistone cluster 1, H3b0.253
ING5inhibitor of growth family, member 50.230
UHRF2ubiquitin-like with PHD and ring finger domains 20.208
CCNT1cyclin T10.207
DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2)0.204
WRNWerner syndrome, RecQ helicase-like0.200
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)0.196
TAF6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa0.193
JMJD6jumonji domain containing 60.178
RB1retinoblastoma 10.177
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa0.174
CSRP2BPCSRP2 binding protein0.173
CHRAC1chromatin accessibility complex 10.169
USP42ubiquitin specific peptidase 420.164
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa0.164
SAP30Sin3A-associated protein, 30kDa0.159
C20orf20chromosome 20 open reading frame 200.151
MED1mediator complex subunit 10.145
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.142
RUNX1runt-related transcription factor 10.141
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa0.141
TCF4transcription factor 40.141
ATMataxia telangiectasia mutated0.139
NCOA3nuclear receptor coactivator 30.138
KDM6Blysine (K)-specific demethylase 6B0.135
PIAS4protein inhibitor of activated STAT, 40.132
TAB3TGF-beta activated kinase 1/MAP3K7 binding protein 30.128
TADA1transcriptional adaptor 10.122
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.114
NCOR1nuclear receptor corepressor 10.112
NCOA6nuclear receptor coactivator 60.109
NCOA2nuclear receptor coactivator 20.106
DRAP1DR1-associated protein 1 (negative cofactor 2 alpha)0.103
RCOR1REST corepressor 10.102
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.101
NR4A1nuclear receptor subfamily 4, group A, member 10.097
MCPH1microcephalin 10.094
ZNF217zinc finger protein 2170.091
GDI1GDP dissociation inhibitor 10.091
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Kat2aK(lysine) acetyltransferase 2A1.000
Arid1aAT rich interactive domain 1A (SWI-like)0.998
Clockcircadian locomotor output cycles kaput0.998
Cry2cryptochrome 2 (photolyase-like)0.992
Per2period homolog 2 (Drosophila)0.971
Trraptransformation/transcription domain-associated protein0.969
Trp53transformation related protein 530.966
Arntlaryl hydrocarbon receptor nuclear translocator-like0.965
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.963
Per1period homolog 1 (Drosophila)0.927
Sin3atranscriptional regulator, SIN3A (yeast)0.914
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.896
Brca1breast cancer 10.837
Tada2atranscriptional adaptor 2A0.833
CrebbpCREB binding protein0.811
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.806
Cry1cryptochrome 1 (photolyase-like)0.674
Ep300E1A binding protein p3000.651
Trp63transformation related protein 630.553
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.510
Yeats2YEATS domain containing 20.428
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.416
Wdr5WD repeat domain 50.402
Atmataxia telangiectasia mutated homolog (human)0.378
Tcf3transcription factor 30.322
Chd4chromodomain helicase DNA binding protein 40.320
Tada3transcriptional adaptor 30.297
Scaf4SR-related CTD-associated factor 40.255
Zfp598zinc finger protein 5980.220
Stat2signal transducer and activator of transcription 20.210
SpenSPEN homolog, transcriptional regulator (Drosophila)0.193
Sfpi1SFFV proviral integration 10.185
Tal1T-cell acute lymphocytic leukemia 10.177
Runx1runt related transcription factor 10.174
Sf1splicing factor 10.159
Men1multiple endocrine neoplasia 10.131
Brca2breast cancer 20.127
Casc3cancer susceptibility candidate 30.127
Tcf7transcription factor 7, T-cell specific0.115
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.112
Csnk1ecasein kinase 1, epsilon0.109
Atxn2lataxin 2-like0.102
Ifnginterferon gamma0.099
Stat1signal transducer and activator of transcription 10.099
Mecp2methyl CpG binding protein 20.096
Esr1estrogen receptor 1 (alpha)0.091
Prr12proline rich 120.090
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.087
Safb2scaffold attachment factor B20.085
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.078
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.077
Brd3bromodomain containing 30.076
Arid1bAT rich interactive domain 1B (SWI-like)0.075
Tcf4transcription factor 40.073
Hdac1histone deacetylase 10.072
Wbp7WW domain binding protein 70.072
Paxip1PAX interacting (with transcription-activation domain) protein 10.071
Creb1cAMP responsive element binding protein 10.067
Per3period homolog 3 (Drosophila)0.064
Myf5myogenic factor 50.062
Irf9interferon regulatory factor 90.061
Zfp592zinc finger protein 5920.061
Stat6signal transducer and activator of transcription 60.061
Ncoa3nuclear receptor coactivator 30.061
Taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor0.061
Helzhelicase with zinc finger domain0.058
Ep400E1A binding protein p4000.058
Asxl1additional sex combs like 1 (Drosophila)0.057
Fbrsfibrosin0.056
Pum1pumilio 1 (Drosophila)0.053
Irs2insulin receptor substrate 20.052
Phf12PHD finger protein 120.050
Traf6TNF receptor-associated factor 60.048
Gigyf1GRB10 interacting GYF protein 10.047
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.047
Smad4MAD homolog 4 (Drosophila)0.046
Usp18ubiquitin specific peptidase 180.045
Mdm4transformed mouse 3T3 cell double minute 40.045
Cdk9cyclin-dependent kinase 9 (CDC2-related kinase)0.044
Pitx2paired-like homeodomain transcription factor 20.043
Med13lmediator complex subunit 13-like0.042
Xpo6exportin 60.041
Pgrprogesterone receptor0.041
Ifnar2interferon (alpha and beta) receptor 20.041
Smad1MAD homolog 1 (Drosophila)0.041
DaxxFas death domain-associated protein0.040
Brd2bromodomain containing 20.039
Stat3signal transducer and activator of transcription 30.038
Fbxl6F-box and leucine-rich repeat protein 60.038
Irf8interferon regulatory factor 80.038
Myf6myogenic factor 60.037
Hcfc1host cell factor C10.037
Tefthyrotroph embryonic factor0.036
Bptfbromodomain PHD finger transcription factor0.035
Cnot3CCR4-NOT transcription complex, subunit 30.035
Cramp1lCrm, cramped-like (Drosophila)0.035
Usp2ubiquitin specific peptidase 20.035
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.034
Acin1apoptotic chromatin condensation inducer 10.034
Pou2f1POU domain, class 2, transcription factor 10.034
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Srrm1serine/arginine repetitive matrix 10.330
Stxbp3syntaxin binding protein 30.226
Chd4chromodomain helicase DNA binding protein 40.215
Ugp2UDP-glucose pyrophosphorylase 20.190
Cherpcalcium homeostasis endoplasmic reticulum protein0.180
Axin1axin 10.151
Ubtfupstream binding transcription factor, RNA polymerase I0.142
Ash1lash1 (absent, small, or homeotic)-like (Drosophila)0.109
Nup210nucleoporin 2100.095
Trim28tripartite motif-containing 280.090
Dcaf7DDB1 and CUL4 associated factor 70.089
Fam193afamily with sequence similarity 193, member A0.089
Tcfe2atranscription factor E2a0.079
Sf3b2splicing factor 3b, subunit 20.072
Parp1poly (ADP-ribose) polymerase 10.071
Mak10MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae)0.069
Arih2ariadne homolog 2 (Drosophila)0.066
Cdca4cell division cycle associated 40.062
Usp36ubiquitin specific peptidase 360.062
Phf12PHD finger protein 120.055
Pom121nuclear pore membrane protein 1210.054
Mta2metastasis associated 1 family, member 20.053
Nup188nucleoporin 1880.050
Lbrlamin B receptor0.048
RGD1561878similar to mKIAA0978 protein0.046
Wizwidely-interspaced zinc finger motifs0.045
Mpripmyosin phosphatase Rho interacting protein0.045
Sik1salt-inducible kinase 10.044
CrebbpCREB binding protein0.043
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.042
Eif4enif1eukaryotic translation initiation factor 4E nuclear import factor 10.042
Snrnp27small nuclear ribonucleoprotein 27 (U4/U6.U5)0.042
Twist1twist homolog 1 (Drosophila)0.041
Cpsf1cleavage and polyadenylation specific factor 10.041
Map3k7ip2mitogen-activated protein kinase kinase kinase 7 interacting protein 20.040
Gtf2igeneral transcription factor II I0.039
Ep400E1A binding protein p4000.039
Paxip1PAX interacting (with transcription-activation domain) protein 10.038
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.037
LOC690911similar to Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein)0.036
Triap1TP53 regulated inhibitor of apoptosis 10.035
Tsen15tRNA splicing endonuclease 15 homolog (S. cerevisiae)0.035
Timelesstimeless homolog (Drosophila)0.035
LOC682469similar to jumonji domain containing 1B0.035
Myst3MYST histone acetyltransferase (monocytic leukemia) 30.034
Hnrnpul1heterogeneous nuclear ribonucleoprotein U-like 10.033
Ehmt1euchromatic histone-lysine N-methyltransferase 10.032
Map2k7mitogen activated protein kinase kinase 70.031
Brd4bromodomain containing 40.031
RGD1305572similar to hypothetical protein MGC306180.031
Suv39h1suppressor of variegation 3-9 homolog 1 (Drosophila)0.031
Arid2AT rich interactive domain 2 (Arid-rfx like)0.030
RGD1565096similar to TSG118.10.030
RGD1307279similar to RIKEN cDNA 2700002I200.029
Ipo9importin 90.029
Hdac1lhistone deacetylase 1-like0.029
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.028
SlkSTE20-like kinase (yeast)0.028
Lrrc47leucine rich repeat containing 470.027
Sf3b4splicing factor 3b, subunit 40.027
Dhx38DEAH (Asp-Glu-Ala-His) box polypeptide 380.026
Papd5PAP associated domain containing 50.026
LOC685909similar to H2A histone family, member V isoform 10.026
Prkd3protein kinase D30.026
Setd5SET domain containing 50.026
Sin3aSIN3 homolog A, transcription regulator (yeast)0.026
Ints5integrator complex subunit 50.025
Sfrs4splicing factor, arginine/serine-rich 40.025
Suv420h1suppressor of variegation 4-20 homolog 1 (Drosophila)0.025
LOC684993hypothetical protein LOC6849930.025
Bat2d1BAT2 domain containing 10.025
KhsrpKH-type splicing regulatory protein0.024
Mcm5minichromosome maintenance complex component 50.024
Golga7golgi autoantigen, golgin subfamily a, 70.024
Rai1retinoic acid induced 10.023
Fkbp4FK506 binding protein 40.023
Prpf8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)0.023
Safbscaffold attachment factor B0.023
Usp7ubiquitin specific peptidase 7 (herpes virus-associated)0.023
Xpo5exportin 50.023
Aglamylo-1,6-glucosidase, 4-alpha-glucanotransferase0.023
Larp1La ribonucleoprotein domain family, member 10.022
Prr5lproline rich 5 like0.022
Scribscribbled homolog (Drosophila)0.022
Hmgxb4HMG box domain containing 40.022
Pias1protein inhibitor of activated STAT, 10.022
Utp15UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)0.021
Epc2enhancer of polycomb homolog 2 (Drosophila)0.021
Fgf18fibroblast growth factor 180.021
Tob2transducer of ERBB2, 20.021
Morc2MORC family CW-type zinc finger 20.021
Adnpactivity-dependent neuroprotector homeobox0.021
Osbpl9oxysterol binding protein-like 90.021
Ldb1LIM domain binding 10.021
Pim3pim-3 oncogene0.021
Fbrsl1fibrosin-like 10.020
Ep300E1A binding protein p3000.020
Brp16brain protein 160.020
Ccdc21coiled-coil domain containing 210.020
Sf3b3splicing factor 3b, subunit 30.020