The network for 'regulation of microtubule polymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of microtubule polymerization

Any process that modulates the frequency, rate or extent of microtubule polymerization.

NameDescriptionProbabilityFunc Analog Organism
ASK1Ask1p1.000
DUO1Duo1p0.988
DAM1Dam1p0.984
SPC34Spc34p0.975
DAD4Dad4p0.951
DAD2Dad2p0.932
DAD1Dad1p0.907
HSK3Hsk3p0.696
SPC19Spc19p0.601
DAD3Dad3p0.181
MDS3Mds3p0.083
KAR9Kar9p0.031
STU2Stu2p0.029
AKL1Akl1p0.027
BIM1Bim1p0.026
DSN1Dsn1p0.022
ARP10Arp10p0.022
FPK1Fpk1p0.021
PCL9Pcl9p0.019
SRD1Srd1p0.017
LEU2Leu2p0.015
YLR162Whypothetical protein0.015
PRP28Prp28p0.015
YOL038C-Ahypothetical protein0.014
YIR035Chypothetical protein0.014
YLR264C-Ahypothetical protein0.014
YIR014Whypothetical protein0.013
ARG8Arg8p0.013
HOT1Hot1p0.012
TAF8Taf8p0.012
MER1Mer1p0.012
MF(ALPHA)2Mf(alpha)2p0.012
PRS2Prs2p0.012
HPF1Hpf1p0.012
CBF2Cbf2p0.012
YAR068Whypothetical protein0.011
YLR132Chypothetical protein0.010
CRP1Crp1p0.010
YBR235Whypothetical protein0.010
ALT2Alt2p0.010
MF(ALPHA)1Mf(alpha)1p0.010
KIP2Kip2p0.010
URA3Ura3p0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
C35E7.8Protein C35E7.80.013
cyl-1Protein CYL-10.013
prp-17Protein PRP-170.013
F43G9.2Protein F43G9.20.012
F42A8.3Protein F42A8.30.011
CELE_Y53C10A.6Protein Y53C10A.60.011
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MAPTmicrotubule-associated protein tau0.957
ZNF746zinc finger protein 7460.887
ARL2ADP-ribosylation factor-like 20.872
TERF2IPtelomeric repeat binding factor 2, interacting protein0.787
FYNFYN oncogene related to SRC, FGR, YES0.711
MAPRE2microtubule-associated protein, RP/EB family, member 20.658
KIF5Bkinesin family member 5B0.577
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.536
NEK6NIMA (never in mitosis gene a)-related kinase 60.532
TBCDtubulin folding cofactor D0.431
MAPRE3microtubule-associated protein, RP/EB family, member 30.428
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.376
ERBB2IPerbb2 interacting protein0.375
TINF2TERF1 (TRF1)-interacting nuclear factor 20.361
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.337
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.328
CDK2cyclin-dependent kinase 20.308
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.304
FYBFYN binding protein0.258
LMO2LIM domain only 2 (rhombotin-like 1)0.257
GSK3Bglycogen synthase kinase 3 beta0.254
TEX11testis expressed 110.246
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.243
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.236
PINX1PIN2/TERF1 interacting, telomerase inhibitor 10.201
DCTN1dynactin 10.189
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.162
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.152
MARK1MAP/microtubule affinity-regulating kinase 10.113
TACC3transforming, acidic coiled-coil containing protein 30.107
FOSFBJ murine osteosarcoma viral oncogene homolog0.106
SMAD9SMAD family member 90.099
CCDC85Acoiled-coil domain containing 85A0.096
VPS29vacuolar protein sorting 29 homolog (S. cerevisiae)0.093
JUNjun proto-oncogene0.081
KIF2Ckinesin family member 2C0.076
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.073
FNBP1formin binding protein 10.071
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.071
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.062
ARL3ADP-ribosylation factor-like 30.061
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.059
TACC1transforming, acidic coiled-coil containing protein 10.059
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 10.054
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.054
CLIP1CAP-GLY domain containing linker protein 10.048
TOP3Atopoisomerase (DNA) III alpha0.044
SPTBN1spectrin, beta, non-erythrocytic 10.042
SPRR2Asmall proline-rich protein 2A0.041
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.041
VAV1vav 1 guanine nucleotide exchange factor0.039
APCadenomatous polyposis coli0.039
CALM1calmodulin 1 (phosphorylase kinase, delta)0.038
MAP2K4mitogen-activated protein kinase kinase 40.037
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 10.037
DSTdystonin0.036
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.036
MAPRE1microtubule-associated protein, RP/EB family, member 10.034
ORC1origin recognition complex, subunit 10.032
TUBA4Atubulin, alpha 4a0.031
GADD45Ggrowth arrest and DNA-damage-inducible, gamma0.030
LRRK2leucine-rich repeat kinase 20.027
REEP5receptor accessory protein 50.022
BIN1bridging integrator 10.021
TNKS2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.021
FOXM1forkhead box M10.020
EZRezrin0.020
NR4A2nuclear receptor subfamily 4, group A, member 20.020
ZFP106zinc finger protein 106 homolog (mouse)0.020
GRAP2GRB2-related adaptor protein 20.019
STIP1stress-induced-phosphoprotein 10.019
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.019
ATMataxia telangiectasia mutated0.017
YAP1Yes-associated protein 10.017
GPRASP2G protein-coupled receptor associated sorting protein 20.017
SIAH1seven in absentia homolog 1 (Drosophila)0.015
KIF4Akinesin family member 4A0.015
TERF1telomeric repeat binding factor (NIMA-interacting) 10.015
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.015
ACDadrenocortical dysplasia homolog (mouse)0.015
SMC1Astructural maintenance of chromosomes 1A0.015
MTUS2microtubule associated tumor suppressor candidate 20.013
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.013
S100A6S100 calcium binding protein A60.013
NGFRnerve growth factor receptor0.012
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.012
APC2adenomatosis polyposis coli 20.012
ARHGEF2Rho/Rac guanine nucleotide exchange factor (GEF) 20.012
HSPA1Bheat shock 70kDa protein 1B0.012
PDE4DIPphosphodiesterase 4D interacting protein0.012
TUBA1Ctubulin, alpha 1c0.012
PDPK13-phosphoinositide dependent protein kinase-10.012
ZRANB1zinc finger, RAN-binding domain containing 10.011
DUSP1dual specificity phosphatase 10.011
CTNNBL1catenin, beta like 10.011
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.011
TUBA1Btubulin, alpha 1b0.011
VAV3vav 3 guanine nucleotide exchange factor0.010
SCRIBscribbled homolog (Drosophila)0.010
LMF2lipase maturation factor 20.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.992
Rb1retinoblastoma 10.904
Ctnnb1catenin (cadherin associated protein), beta 10.608
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.526
Arandrogen receptor0.435
Apcadenomatosis polyposis coli0.398
Ptenphosphatase and tensin homolog0.368
Cdkn1bcyclin-dependent kinase inhibitor 1B0.323
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.285
Cdkn2dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.227
Kitkit oncogene0.213
Hrhairless0.205
Tgfb1transforming growth factor, beta 10.188
Mdm2transformed mouse 3T3 cell double minute 20.184
Ccnd1cyclin D10.163
BrafBraf transforming gene0.143
WwoxWW domain-containing oxidoreductase0.118
Leprleptin receptor0.118
Ptch1patched homolog 10.118
Tsc1tuberous sclerosis 10.106
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.095
Wdr1WD repeat domain 10.088
Lhcgrluteinizing hormone/choriogonadotropin receptor0.084
Ahraryl-hydrocarbon receptor0.083
Psapprosaposin0.081
Msh2mutS homolog 2 (E. coli)0.065
Gsk3bglycogen synthase kinase 3 beta0.062
Trp63transformation related protein 630.062
Snap25synaptosomal-associated protein 250.059
Cdkn2acyclin-dependent kinase inhibitor 2A0.056
Ptpn11protein tyrosine phosphatase, non-receptor type 110.055
Stat3signal transducer and activator of transcription 30.054
Arpc4actin related protein 2/3 complex, subunit 40.051
Pot1aprotection of telomeres 1A0.048
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.043
Nf1neurofibromatosis 10.041
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.039
Pacsin1protein kinase C and casein kinase substrate in neurons 10.039
Klf5Kruppel-like factor 50.035
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.031
Tpx2TPX2, microtubule-associated protein homolog (Xenopus laevis)0.028
Pcdhgb1protocadherin gamma subfamily B, 10.027
Foxo3forkhead box O30.026
Kiss1rKISS1 receptor0.025
Nbnnibrin0.025
Smad3MAD homolog 3 (Drosophila)0.025
Klc1kinesin light chain 10.024
Nf2neurofibromatosis 20.023
Notch2Notch gene homolog 2 (Drosophila)0.023
Cdk4cyclin-dependent kinase 40.023
Drd2dopamine receptor D20.023
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.022
Mdm4transformed mouse 3T3 cell double minute 40.021
Psen1presenilin 10.021
Irs2insulin receptor substrate 20.020
Esr2estrogen receptor 2 (beta)0.018
Lrrk2leucine-rich repeat kinase 20.018
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.018
Acdadrenocortical dysplasia0.017
Pomcpro-opiomelanocortin-alpha0.017
Stk11serine/threonine kinase 110.017
Clasp1CLIP associating protein 10.017
Brca1breast cancer 10.016
Ezh2enhancer of zeste homolog 2 (Drosophila)0.015
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.014
Thbs1thrombospondin 10.014
Gap43growth associated protein 430.013
Rhoaras homolog gene family, member A0.013
FosFBJ osteosarcoma oncogene0.013
Jak2Janus kinase 20.013
Ncaphnon-SMC condensin I complex, subunit H0.012
JunJun oncogene0.012
Cplx1complexin 10.012
Foxp3forkhead box P30.012
Ptgs1prostaglandin-endoperoxide synthase 10.011
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.011
HopxHOP homeobox0.010
Runx1runt related transcription factor 10.010
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100362824caveolin 2-like0.798
Stip1stress-induced phosphoprotein 10.198
Syt4synaptotagmin IV0.146
Errfi1ERBB receptor feedback inhibitor 10.126
Rnf4ring finger protein 40.062
Ehd2EH-domain containing 20.059
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.057
Emp1epithelial membrane protein 10.047
Jak1Janus kinase 10.035
Mllt11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 110.033
Map2k4mitogen activated protein kinase kinase 40.031
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.028
Bcat1branched chain aminotransferase 1, cytosolic0.028
Vegfavascular endothelial growth factor A0.020
Mtus1mitochondrial tumor suppressor 10.020
Il6rinterleukin 6 receptor0.019
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.017
Dnm1ldynamin 1-like0.017
Fgf9fibroblast growth factor 90.016
Cyb5r1cytochrome b5 reductase 10.016
SnrkSNF related kinase0.016
Rab3aRAB3A, member RAS oncogene family0.015
Arf1ADP-ribosylation factor 10.014
JunJun oncogene0.013
SnurfSNRPN upstream reading frame0.013
Slc4a3solute carrier family 4 (anion exchanger), member 30.013
Vdac1voltage-dependent anion channel 10.013
Klc2kinesin light chain 20.012
Hsf1heat shock transcription factor 10.012
Ognosteoglycin0.012
Ndrg4N-myc downstream regulated gene 40.011
HrasHarvey rat sarcoma virus oncogene0.011
KitlgKIT ligand0.011
Cdk5cyclin-dependent kinase 50.011