The network for 'regulation of response to drug' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to drug

Any process that modulates the frequency, rate or extent of response to drug.

NameDescriptionProbabilityFunc Analog Organism
SWI1Swi1p0.099
VID24Vid24p0.097
TRA1Tra1p0.087
GLN3Gln3p0.083
HXT3Hxt3p0.082
VAC7Vac7p0.061
NRG1Nrg1p0.056
TPO2Tpo2p0.056
MDH2Mdh2p0.054
KOG1Kog1p0.053
CSR2Csr2p0.051
STE5Ste5p0.050
MIG1Mig1p0.048
GAL11Gal11p0.048
BSD2Bsd2p0.047
MBR1Mbr1p0.046
YPL014Whypothetical protein0.043
GND2Gnd2p0.042
YPR157Whypothetical protein0.042
RGS2Rgs2p0.042
HOR2Hor2p0.041
LYS5Lys5p0.041
GAL4Gal4p0.040
YOR385Whypothetical protein0.039
PSK2Psk2p0.038
ADR1Adr1p0.037
MOT3Mot3p0.036
TOF2Tof2p0.035
ATG29Atg29p0.035
HAL5Hal5p0.035
PHO80Pho80p0.034
PNS1Pns1p0.034
SSK2Ssk2p0.034
MTC4Mtc4p0.034
RPI1Rpi1p0.034
SMP1Smp1p0.034
RTG3Rtg3p0.033
ZAP1Zap1p0.033
SFL1Sfl1p0.033
YNL234Whypothetical protein0.032
DCS2Dcs2p0.032
PDR5Pdr5p0.032
YPL150Whypothetical protein0.031
AGC1Agc1p0.031
GAT2Gat2p0.031
SIP2Sip2p0.030
YNR014Whypothetical protein0.030
GPD1Gpd1p0.030
YKR075Chypothetical protein0.030
SRD1Srd1p0.029
PHO12Pho12p0.029
DAL81Dal81p0.029
HAL1Hal1p0.029
MNN4Mnn4p0.029
POG1Pog1p0.029
GUT2Gut2p0.029
ZWF1Zwf1p0.028
DBF2Dbf2p0.028
YAP5Yap5p0.028
MIG2Mig2p0.028
ECM30Ecm30p0.028
AFT1Aft1p0.028
LEU2Leu2p0.028
DIA1Dia1p0.027
YIR035Chypothetical protein0.027
PUT4Put4p0.027
KDX1Kdx1p0.027
TYE7Tye7p0.027
YOL038C-Ahypothetical protein0.027
WAR1War1p0.027
FPK1Fpk1p0.027
AVO1Avo1p0.027
SBE22Sbe22p0.027
CHS2Chs2p0.026
ACS1Acs1p0.026
GAD1Gad1p0.026
TSC11Tsc11p0.026
BSC1Bsc1p0.026
YER130Chypothetical protein0.026
YLR162Whypothetical protein0.026
FMP48Fmp48p0.026
KIC1Kic1p0.026
HXT7Hxt7p0.026
YLR264C-Ahypothetical protein0.026
SAK1Sak1p0.026
RTG1Rtg1p0.026
GPH1Gph1p0.026
STL1Stl1p0.025
YIR042Chypothetical protein0.025
CHA1Cha1p0.025
RIM13Rim13p0.025
ICY1Icy1p0.025
YPL066Whypothetical protein0.025
YAR068Whypothetical protein0.025
TIP1Tip1p0.025
YKL187Chypothetical protein0.025
ACH1Ach1p0.025
WSC4Wsc4p0.025
FAA2Faa2p0.025
HOR7Hor7p0.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
msxemuscle segment homeobox E0.037
LOC565632BTB/POZ domain-containing protein 16-like0.033
si:ch1073-268b21.1si:ch1073-268b21.10.031
nkx2.1aNK2 homeobox 1a0.021
ephb4aeph receptor B4a0.021
dyx1c1dyslexia susceptibility 1 candidate 10.018
LOC793222cAMP-dependent protein kinase inhibitor alpha-like0.013
ccdc73coiled-coil domain containing 730.013
si:dkey-183g16.1si:dkey-183g16.10.013
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.011
LOC558198probable endonuclease 4-like0.011
wu:fi34b01wu:fi34b010.010
wu:fk73b01wu:fk73b010.010
zgc:171747zgc:1717470.010
si:ch211-198o12.4si:ch211-198o12.40.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MED25mediator complex subunit 250.279
MAPK1mitogen-activated protein kinase 10.279
AKT1v-akt murine thymoma viral oncogene homolog 10.187
RPTORregulatory associated protein of MTOR, complex 10.128
MAPK3mitogen-activated protein kinase 30.125
KANK2KN motif and ankyrin repeat domains 20.074
DUSP1dual specificity phosphatase 10.069
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.063
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.056
RICTORRPTOR independent companion of MTOR, complex 20.056
RXRAretinoid X receptor, alpha0.056
AFF1AF4/FMR2 family, member 10.044
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.042
COASYCoA synthase0.041
RARAretinoic acid receptor, alpha0.040
ALDH1A1aldehyde dehydrogenase 1 family, member A10.038
DUSP3dual specificity phosphatase 30.037
PRKCAprotein kinase C, alpha0.036
AFF4AF4/FMR2 family, member 40.034
DEPTORDEP domain containing MTOR-interacting protein0.033
NCOA3nuclear receptor coactivator 30.033
C16orf53chromosome 16 open reading frame 530.029
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.028
EP300E1A binding protein p3000.027
MAP2K1mitogen-activated protein kinase kinase 10.023
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.022
MAPK14mitogen-activated protein kinase 140.021
AKT1S1AKT1 substrate 1 (proline-rich)0.021
CCNT1cyclin T10.021
NCOA6nuclear receptor coactivator 60.019
HTThuntingtin0.018
PTPRJprotein tyrosine phosphatase, receptor type, J0.018
PTPRRprotein tyrosine phosphatase, receptor type, R0.017
NCOA2nuclear receptor coactivator 20.017
PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 10.016
PDK1pyruvate dehydrogenase kinase, isozyme 10.016
MAPTmicrotubule-associated protein tau0.016
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 20.016
DUSP7dual specificity phosphatase 70.014
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.012
PEA15phosphoprotein enriched in astrocytes 150.012
PDPK13-phosphoinositide dependent protein kinase-10.012
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.011
BRAFv-raf murine sarcoma viral oncogene homolog B10.011
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.010
MAPKAP1mitogen-activated protein kinase associated protein 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 21.000
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.986
Grid1glutamate receptor, ionotropic, delta 10.934
Gabra1gamma-aminobutyric acid (GABA) A receptor, subunit alpha 10.918
Gabra5gamma-aminobutyric acid (GABA) A receptor, subunit alpha 50.916
Gabrg2gamma-aminobutyric acid (GABA) A receptor, subunit gamma 20.884
RictorRPTOR independent companion of MTOR, complex 20.724
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.716
Gabrg1gamma-aminobutyric acid (GABA) A receptor, subunit gamma 10.658
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.613
BrafBraf transforming gene0.577
Ep300E1A binding protein p3000.536
Gad2glutamic acid decarboxylase 20.498
Mapkap1mitogen-activated protein kinase associated protein 10.400
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.393
B3galt1UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 10.379
Nxph1neurexophilin 10.370
Nr3c1nuclear receptor subfamily 3, group C, member 10.341
Ncoa1nuclear receptor coactivator 10.324
Thrbthyroid hormone receptor beta0.322
Rptorregulatory associated protein of MTOR, complex 10.308
Rit2Ras-like without CAAX 20.290
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.268
Cnr1cannabinoid receptor 1 (brain)0.262
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.255
Scn1asodium channel, voltage-gated, type I, alpha0.251
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.230
Cdh9cadherin 90.227
Setdb1SET domain, bifurcated 10.224
Ptprrprotein tyrosine phosphatase, receptor type, R0.222
Bcl2B-cell leukemia/lymphoma 20.204
Dlg4discs, large homolog 4 (Drosophila)0.199
Hcn1hyperpolarization-activated, cyclic nucleotide-gated K+ 10.194
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.184
Nrsn1neurensin 10.182
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.179
Cdh10cadherin 100.174
Kif5ckinesin family member 5C0.172
Tnrc6ctrinucleotide repeat containing 6C0.171
Pias1protein inhibitor of activated STAT 10.171
Cntn4contactin 40.168
Grik2glutamate receptor, ionotropic, kainate 2 (beta 2)0.165
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae)0.150
Syt1synaptotagmin I0.148
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.145
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.139
SrcRous sarcoma oncogene0.127
Gabrg3gamma-aminobutyric acid (GABA) A receptor, subunit gamma 30.125
Gabrb1gamma-aminobutyric acid (GABA) A receptor, subunit beta 10.123
Mdm2transformed mouse 3T3 cell double minute 20.118
Cntn3contactin 30.117
Rasgrp1RAS guanyl releasing protein 10.116
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.114
Trhrthyrotropin releasing hormone receptor0.114
Mapk14mitogen-activated protein kinase 140.112
CblCasitas B-lineage lymphoma0.112
CrebbpCREB binding protein0.109
Cdh8cadherin 80.109
Mid1midline 10.109
Rerearginine glutamic acid dipeptide (RE) repeats0.109
Adcyap1adenylate cyclase activating polypeptide 10.106
Nap1l2nucleosome assembly protein 1-like 20.104
En2engrailed 20.102
Ncor1nuclear receptor co-repressor 10.100
Grm8glutamate receptor, metabotropic 80.100
Mapk3mitogen-activated protein kinase 30.097
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.097
Camk4calcium/calmodulin-dependent protein kinase IV0.092
Nf1neurofibromatosis 10.091
Neurod1neurogenic differentiation 10.089
Resp18regulated endocrine-specific protein 180.088
Syn2synapsin II0.087
Mapk8mitogen-activated protein kinase 80.087
Pikfyvephosphoinositide kinase, FYVE finger containing0.086
Macf1microtubule-actin crosslinking factor 10.086
Gjd2gap junction protein, delta 20.085
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.083
NapbN-ethylmaleimide sensitive fusion protein attachment protein beta0.081
Dync1i1dynein cytoplasmic 1 intermediate chain 10.080
En1engrailed 10.080
Pea15aphosphoprotein enriched in astrocytes 15A0.079
Slc12a5solute carrier family 12, member 50.077
Mgat4cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)0.076
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.076
Glg1golgi apparatus protein 10.076
Prkccprotein kinase C, gamma0.074
Plcb1phospholipase C, beta 10.074
Oprk1opioid receptor, kappa 10.067
Npy1rneuropeptide Y receptor Y10.067
CadpsCa2+-dependent secretion activator0.067
Fbxw7F-box and WD-40 domain protein 70.065
Dlg2discs, large homolog 2 (Drosophila)0.064
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.064
Ash1lash1 (absent, small, or homeotic)-like (Drosophila)0.063
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.061
Map3k5mitogen-activated protein kinase kinase kinase 50.061
Gpatch2G patch domain containing 20.061
Tsc1tuberous sclerosis 10.060
Mapk1mitogen-activated protein kinase 10.059
Bsnbassoon0.058
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dnm1ldynamin 1-like0.013