The network for 'double strand break repair via break induced replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

double strand break repair via break induced replication

The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.

NameDescriptionProbabilityFunc Analog Organism
MCM4Mcm4p0.996
SLD5Sld5p0.987
MCM3Mcm3p0.966
MCM6Mcm6p0.877
PSF1Psf1p0.870
MRC1Mrc1p0.840
DBF4Dbf4p0.797
MCM2Mcm2p0.797
SLD2Sld2p0.796
CTF4Ctf4p0.777
MCM5Mcm5p0.583
RAD53Rad53p0.542
TOF1Tof1p0.525
PSF2Psf2p0.511
DPB11Dpb11p0.505
MCM7Mcm7p0.492
MCM10Mcm10p0.455
DPB2Dpb2p0.419
CDC45Cdc45p0.408
RAD9Rad9p0.294
POL31Pol31p0.265
CDC6Cdc6p0.194
POL3Pol3p0.189
RAD5Rad5p0.189
DIA2Dia2p0.182
POL12Pol12p0.178
DDC1Ddc1p0.138
SMC6Smc6p0.115
TOP3Top3p0.103
SRS2Srs2p0.093
POL2Pol2p0.089
MEC1Mec1p0.080
RAD18Rad18p0.080
POL1Pol1p0.075
YOR060Chypothetical protein0.074
RAD1Rad1p0.074
RAD24Rad24p0.062
SGS1Sgs1p0.059
RAD10Rad10p0.059
PRI1Pri1p0.055
SLD3Sld3p0.055
DUN1Dun1p0.053
RAD17Rad17p0.053
PRI2Pri2p0.051
SAE2Sae2p0.051
PSF3Psf3p0.047
RFA2Rfa2p0.047
CSM3Csm3p0.042
ACM1Acm1p0.041
EST2Est2p0.038
RFA1Rfa1p0.033
MMS21Mms21p0.031
SRD1Srd1p0.029
TAH11Tah11p0.029
XRS2Xrs2p0.028
ADH2Adh2p0.028
ARP10Arp10p0.026
MGS1Mgs1p0.025
YAR068Whypothetical protein0.025
YOL038C-Ahypothetical protein0.025
LEU2Leu2p0.025
YLR264C-Ahypothetical protein0.025
RMI1Rmi1p0.024
MMS22Mms22p0.024
MMS1Mms1p0.023
YLR162Whypothetical protein0.023
HXT3Hxt3p0.022
RAD55Rad55p0.022
MER1Mer1p0.022
HOR2Hor2p0.022
PDS1Pds1p0.021
ARG8Arg8p0.021
REV7Rev7p0.021
ATP6Atp6p0.020
IML1Iml1p0.020
RAD54Rad54p0.020
ZPS1Zps1p0.019
YPR157Whypothetical protein0.019
YLR042Chypothetical protein0.019
YAR066Whypothetical protein0.019
YBR013Chypothetical protein0.018
HST3Hst3p0.018
HPF1Hpf1p0.018
CUP1-1Cup1-1p0.018
SPL2Spl2p0.017
RAD59Rad59p0.017
POL32Pol32p0.017
MSA1Msa1p0.017
AUA1Aua1p0.017
WSS1Wss1p0.017
SCM4Scm4p0.017
ESC1Esc1p0.017
YOL013W-Ahypothetical protein0.017
CPD1Cpd1p0.017
SWC7Swc7p0.017
YBL044Whypothetical protein0.016
SLX4Slx4p0.016
CAB4Cab4p0.016
BSC1Bsc1p0.016
MMS4Mms4p0.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism