The network for 'regulation of gluconeogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of gluconeogenesis

Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

NameDescriptionProbabilityFunc Analog Organism
GID7Gid7p0.962
RMD5Rmd5p0.863
GID8Gid8p0.742
MOH1Moh1p0.557
VID30Vid30p0.554
FYV10Fyv10p0.345
GAL83Gal83p0.208
VID24Vid24p0.141
VID28Vid28p0.085
EMI2Emi2p0.065
TMA10Tma10p0.064
ADR1Adr1p0.062
ERT1Ert1p0.053
SUR1Sur1p0.045
COX13Cox13p0.042
HXK1Hxk1p0.040
YAP6Yap6p0.035
BDH1Bdh1p0.034
GLN1Gln1p0.034
RDS2Rds2p0.033
SAK1Sak1p0.031
SNF4Snf4p0.031
CAT8Cat8p0.029
SRD1Srd1p0.028
LEU2Leu2p0.028
KIN1Kin1p0.028
GUT2Gut2p0.027
YLR264C-Ahypothetical protein0.027
SAP4Sap4p0.027
COA4Coa4p0.027
CAR1Car1p0.027
DOG2Dog2p0.026
YLR162Whypothetical protein0.024
YGR205Whypothetical protein0.024
PET191Pet191p0.024
MF(ALPHA)2Mf(alpha)2p0.023
GPT2Gpt2p0.023
YDR186Chypothetical protein0.023
TKL2Tkl2p0.022
HXT7Hxt7p0.021
ARP10Arp10p0.021
HXT6Hxt6p0.021
EMI5Emi5p0.021
ARE2Are2p0.021
YOL038C-Ahypothetical protein0.021
ZPS1Zps1p0.019
CUP1-1Cup1-1p0.019
HOR7Hor7p0.019
YER039C-Ahypothetical protein0.019
HXT3Hxt3p0.019
YHR140Whypothetical protein0.019
YKL187Chypothetical protein0.018
MER1Mer1p0.018
MF(ALPHA)1Mf(alpha)1p0.018
YAR068Whypothetical protein0.018
SSH4Ssh4p0.018
YIL024Chypothetical protein0.018
CIT2Cit2p0.018
COX23Cox23p0.017
SCO1Sco1p0.017
GTO3Gto3p0.017
SPL2Spl2p0.017
ATP6Atp6p0.017
YLR042Chypothetical protein0.016
YBR013Chypothetical protein0.016
PIB1Pib1p0.016
YHR009Chypothetical protein0.016
FAA2Faa2p0.016
GIS1Gis1p0.016
ROD1Rod1p0.016
RIM4Rim4p0.016
AAD10Aad10p0.016
CPD1Cpd1p0.015
HPF1Hpf1p0.015
YPR157Whypothetical protein0.015
YGR017Whypothetical protein0.015
REE1Ree1p0.015
YKR075Chypothetical protein0.015
CTR3Ctr3p0.015
XDJ1Xdj1p0.014
CRP1Crp1p0.014
PTR2Ptr2p0.014
MDH2Mdh2p0.014
AUA1Aua1p0.014
GDH1Gdh1p0.014
RNP1Rnp1p0.014
OPT2Opt2p0.014
SRX1Srx1p0.014
YEL073Chypothetical protein0.014
YAP1801hypothetical protein0.014
YOL013W-Ahypothetical protein0.014
UPS3Ups3p0.014
URA3Ura3p0.013
TYE7Tye7p0.013
SIP4Sip4p0.013
PNC1Pnc1p0.013
OPY2Opy2p0.013
YOR338Whypothetical protein0.013
SRT1Srt1p0.013
YIL029Chypothetical protein0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor1.000
Lepleptin0.977
Insrinsulin receptor0.955
Ppargperoxisome proliferator activated receptor gamma0.905
Tgfb1transforming growth factor, beta 10.829
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.792
Ren1renin 1 structural0.785
Nos1nitric oxide synthase 1, neuronal0.718
C1qacomplement component 1, q subcomponent, alpha polypeptide0.703
Irs2insulin receptor substrate 20.691
C1qccomplement component 1, q subcomponent, C chain0.661
C1qbcomplement component 1, q subcomponent, beta polypeptide0.589
Prlrprolactin receptor0.566
Cdkn1bcyclin-dependent kinase inhibitor 1B0.559
Esr1estrogen receptor 1 (alpha)0.551
LOC100048884novel member of the major urinary protein (Mup) gene family0.515
Mup10major urinary protein 100.502
Nos3nitric oxide synthase 3, endothelial cell0.437
Clk1CDC-like kinase 10.389
Agtr1aangiotensin II receptor, type 1a0.356
Kiss1KiSS-1 metastasis-suppressor0.335
Ghrgrowth hormone receptor0.334
Clk4CDC like kinase 40.295
Ccnl2cyclin L20.279
Pnpla2patatin-like phospholipase domain containing 20.265
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.248
Mup19major urinary protein 190.238
Mup3major urinary protein 30.230
Cav1caveolin 1, caveolae protein0.220
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.218
Hnf4ahepatic nuclear factor 4, alpha0.205
Ulk1Unc-51 like kinase 1 (C. elegans)0.200
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.191
Arandrogen receptor0.188
H2-Aahistocompatibility 2, class II antigen A, alpha0.183
Mup1major urinary protein 10.180
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.173
Stat5bsignal transducer and activator of transcription 5B0.171
Vdrvitamin D receptor0.164
Apoeapolipoprotein E0.144
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.143
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.141
Prpf39PRP39 pre-mRNA processing factor 39 homolog (yeast)0.140
Mup4major urinary protein 40.140
Lipelipase, hormone sensitive0.138
Mup12major urinary protein 120.133
Mup14major urinary protein 140.131
Mup9major urinary protein 90.123
LOC100048885major urinary protein LOC1000488850.118
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.115
VgfVGF nerve growth factor inducible0.110
TyrobpTYRO protein tyrosine kinase binding protein0.106
Arntlaryl hydrocarbon receptor nuclear translocator-like0.105
Igf1insulin-like growth factor 10.102
Clockcircadian locomotor output cycles kaput0.101
Mup17major urinary protein 170.100
Mup13major urinary protein 130.100
Npy1rneuropeptide Y receptor Y10.097
Apoa1apolipoprotein A-I0.096
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.096
Mup8major urinary protein 80.092
Drd2dopamine receptor D20.091
Fgafibrinogen alpha chain0.091
Mup5major urinary protein 50.090
Mup7major urinary protein 70.089
Tdo2tryptophan 2,3-dioxygenase0.086
Mup2major urinary protein 20.085
Akr1c6aldo-keto reductase family 1, member C60.085
Stat3signal transducer and activator of transcription 30.084
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.083
Rbl2retinoblastoma-like 20.081
Trp53transformation related protein 530.081
Slc12a1solute carrier family 12, member 10.079
Mup15major urinary protein 150.078
Vav2vav 2 oncogene0.078
Csf1rcolony stimulating factor 1 receptor0.075
Spry4sprouty homolog 4 (Drosophila)0.074
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.073
Chst8carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 80.072
Serpina3cserine (or cysteine) peptidase inhibitor, clade A, member 3C0.072
Esr2estrogen receptor 2 (beta)0.070
C4bcomplement component 4B (Childo blood group)0.069
Hbb-b1hemoglobin, beta adult major chain0.068
Mup11major urinary protein 110.066
Med12mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)0.061
Prkag1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.060
Thrathyroid hormone receptor alpha0.059
Ly86lymphocyte antigen 860.059
Adipoqadiponectin, C1Q and collagen domain containing0.057
Cps1carbamoyl-phosphate synthetase 10.057
Crhr1corticotropin releasing hormone receptor 10.056
Fabp1fatty acid binding protein 1, liver0.056
Pou3f1POU domain, class 3, transcription factor 10.056
Serpina1aserine (or cysteine) peptidase inhibitor, clade A, member 1A0.054
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.053
Klk1b8kallikrein 1-related peptidase b80.052
Nr1h4nuclear receptor subfamily 1, group H, member 40.050
CrebbpCREB binding protein0.049
Mark4MAP/microtubule affinity-regulating kinase 40.049
Fggfibrinogen gamma chain0.049
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Etfdhelectron-transferring-flavoprotein dehydrogenase0.317
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.307
DbpD site of albumin promoter (albumin D-box) binding protein0.222
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.108
Cpt2carnitine palmitoyltransferase 20.081
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.075
Acat1acetyl-coenzyme A acetyltransferase 10.075
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.072
Acsl1acyl-CoA synthetase long-chain family member 10.072
LOC259246alpha-2u globulin PGCL10.064
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.058
Slc37a4solute carrier family 37 (glucose-6-phosphate transporter), member 40.055
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.048
Pygmphosphorylase, glycogen, muscle0.048
Nfibnuclear factor I/B0.039
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.036
Ldhdlactate dehydrogenase D0.036
RGD1359529similar to chromosome 1 open reading frame 630.036
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.036
Foxo1forkhead box O10.035
Mup5major urinary protein 50.035
Gstm2glutathione S-transferase mu 20.035
Mstnmyostatin0.034
Slco1b3solute carrier organic anion transporter family, member 1b30.034
Ddx17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.031
Casp2caspase 20.031
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.029
Rararetinoic acid receptor, alpha0.028
Purbpurine rich element binding protein B0.027
Acacbacetyl-Coenzyme A carboxylase beta0.027
Nxf1nuclear RNA export factor 10.026
Pqcppolyglutamine-containing protein0.025
Smad7SMAD family member 70.023
Tceb3transcription elongation factor B (SIII), polypeptide 30.023
Pink1PTEN induced putative kinase 10.023
Nr5a2nuclear receptor subfamily 5, group A, member 20.023
Ntn1netrin 10.022
Ak1adenylate kinase 10.022
Akap8lA kinase (PRKA) anchor protein 8-like0.022
Pcmtd2protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 20.022
Rxraretinoid X receptor alpha0.022
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.022
Usf2upstream transcription factor 2, c-fos interacting0.021
Fgd4FYVE, RhoGEF and PH domain containing 40.021
Catcatalase0.021
Gstm7glutathione S-transferase, mu 70.021
LOC259245alpha-2u globulin PGCL50.021
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.021
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.020
Acin1apoptotic chromatin condensation inducer 10.019
TctaT-cell leukemia translocation altered gene0.019
Acaa2acetyl-Coenzyme A acyltransferase 20.019
Map3k7ip1mitogen-activated protein kinase kinase kinase 7 interacting protein 10.019
Sardhsarcosine dehydrogenase0.019
Pxmp2peroxisomal membrane protein 20.019
Trib1tribbles homolog 1 (Drosophila)0.019
Srebf1sterol regulatory element binding transcription factor 10.019
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.018
Pex14peroxisomal biogenesis factor 140.018
Acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.018
Dio1deiodinase, iodothyronine, type I0.018
Sfrs2splicing factor, arginine/serine-rich 20.018
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.018
Slc22a1solute carrier family 22 (organic cation transporter), member 10.018
Nek9NIMA (never in mitosis gene a)- related kinase 90.018
Mug1murinoglobulin 10.018
Vipr1vasoactive intestinal peptide receptor 10.018
RGD1564560similar to RCK0.017
Abtb1ankyrin repeat and BTB (POZ) domain containing 10.017
LOC678880similar to mammalian retrotransposon derived 8b0.017
Cgnl1cingulin-like 10.017
Nfianuclear factor I/A0.017
Pfkmphosphofructokinase, muscle0.017
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.016
Gulogulonolactone (L-) oxidase0.016
Kcnj15potassium inwardly-rectifying channel, subfamily J, member 150.016
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.016
Lphn2latrophilin 20.016
LOC100361864UDP-glucuronosyltransferase 2B3-like0.016
Irf3interferon regulatory factor 30.016
Rbm9RNA binding motif protein 90.016
Brp16brain protein 160.015
Maoamonoamine oxidase A0.015
Igfbp5insulin-like growth factor binding protein 50.015
DaoD-amino-acid oxidase0.015
Il1r1interleukin 1 receptor, type I0.015
Metmet proto-oncogene0.015
Eef2keukaryotic elongation factor-2 kinase0.015
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.015
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.015
Atxn3ataxin 30.015
Rhorhodopsin0.015
Phka1phosphorylase kinase, alpha 10.015
Zbtb20zinc finger and BTB domain containing 200.014
Clk1CDC-like kinase 10.014
Ppap2bphosphatidic acid phosphatase type 2B0.014
Efnb1ephrin B10.014
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.014
Slc25a42solute carrier family 25, member 420.014
Znf692zinc finger protein 6920.014