The network for 'positive regulation of mrna metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mrna metabolic process

Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 30.513
tcf12transcription factor 120.126
brca2breast cancer 2, early onset0.091
snrnp40small nuclear ribonucleoprotein 40 (U5)0.090
fanclFanconi anemia, complementation group L0.089
puf60bpoly-U binding splicing factor b0.081
rnps1RNA binding protein S1, serine-rich domain0.072
ubinataxin-1 ubiquitin-like interacting protein0.064
ilf2interleukin enhancer binding factor 20.055
sf1splicing factor 10.054
vasavasa homolog0.053
nvlnuclear VCP-like0.046
macf1microtubule-actin crosslinking factor 10.046
eef2beukaryotic translation elongation factor 2b0.043
asz1ankyrin repeat, SAM and basic leucine zipper domain containing 10.042
tdrd1tudor domain containing 10.042
ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39b0.038
snrpcsmall nuclear ribonucleoprotein polypeptide C0.037
srsf6aserine/arginine-rich splicing factor 6a0.037
pou3f3aPOU class 3 homeobox 3a0.035
robo1roundabout homolog 10.034
cpsf6cleavage and polyadenylation specific factor 60.033
rbb4lretinoblastoma binding protein 4, like0.033
ctnnb1catenin (cadherin-associated protein), beta 10.032
nup50nucleoporin 500.032
ddx39aaDEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa0.031
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.031
piwil2piwi-like 2 (Drosophila)0.030
piwil1piwi-like 1 (Drosophila)0.029
rbfox1RNA binding protein, fox-1 homolog (C. elegans) 10.028
amhanti-Mullerian hormone0.026
safbscaffold attachment factor B0.026
srsf11serine/arginine-rich splicing factor 110.026
otulOTU like protein0.025
hnrnpmheterogeneous nuclear ribonucleoprotein M0.025
mef2dmyocyte enhancer factor 2d0.025
mosv-mos Moloney murine sarcoma viral oncogene homolog0.025
cstf1cleavage stimulation factor, 3' pre-RNA, subunit 10.025
bucbucky ball0.024
msh6mutS homolog 6 (E. coli)0.024
ccna2cyclin A20.024
rc3rabconnectin 30.023
srrtserrate RNA effector molecule homolog (Arabidopsis)0.023
znf207azinc finger protein 207, a0.022
btg1B-cell translocation gene 10.022
ddx54DEAD (Asp-Glu-Ala-Asp) box polypeptide 540.022
cbx1achromobox homolog 1a (HP1 beta homolog Drosophila)0.022
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.021
znf711zinc finger protein 7110.021
mbnl2muscleblind-like 2 (Drosophila)0.021
atf1activating transcription factor 10.021
naa15aN(alpha)-acetyltransferase 15, NatA auxiliary subunit a0.020
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.020
nrxn1aneurexin 1a0.020
nup155nucleoporin 1550.020
camk2d2calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 20.020
morc2MORC family CW-type zinc finger 20.019
pglyrp2peptidoglycan recognition protein 20.019
rbm4.2RNA binding motif protein 4.20.019
ttkttk protein kinase0.019
nup93nucleoporin 930.019
pdcd11programmed cell death 110.019
gdf9growth differentiation factor 90.019
matr3lmatrin 3-like0.019
cfl2lcofilin 2, like0.018
ube2iubiquitin-conjugating enzyme E2I0.018
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.018
nolc1nucleolar and coiled-body phosphoprotein 10.018
phlda1pleckstrin homology-like domain, family A, member 10.018
gpm6aaglycoprotein M6Aa0.018
sf3a2splicing factor 3a, subunit 20.018
glud1bglutamate dehydrogenase 1b0.018
ilf3ainterleukin enhancer binding factor 3a0.018
polr2bpolymerase (RNA) II (DNA directed) polypeptide B0.017
cherpcalcium homeostasis endoplasmic reticulum protein0.017
tbpl2TATA box binding protein like 20.017
irf2bp2binterferon regulatory factor 2 binding protein 2b0.017
cryba4crystallin, beta A40.017
dmrt3adoublesex and mab-3 related transcription factor 3a0.017
lrrtm1leucine rich repeat transmembrane neuronal 10.016
plp1aproteolipid protein 1a0.016
ecdecdysoneless homolog (Drosophila)0.016
gatmglycine amidinotransferase (L-arginine:glycine amidinotransferase)0.016
syt11asynaptotagmin XIa0.016
dazldaz-like gene0.016
elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.016
eif4heukaryotic translation initiation factor 4h0.016
nusap1nucleolar and spindle associated protein 10.016
ewsr1aEwing sarcoma breakpoint region 1a0.016
med14mediator complex subunit 140.016
LOC567405novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)0.016
dcaf13ddb1 and cul4 associated factor 130.016
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
traltrailer hitch0.269
Ge-1CG6181 gene product from transcript CG6181-RA0.166
MED15Mediator complex subunit 150.121
piwiCG6122 gene product from transcript CG6122-RA0.082
orboo18 RNA-binding protein0.072
otuovarian tumor0.055
ash1absent, small, or homeotic discs 10.049
spn-Espindle E0.043
RpS23Ribosomal protein S230.040
Nipped-BCG17704 gene product from transcript CG17704-RI0.026
bambag of marbles0.024
stilstand still0.022
Tango6Transport and Golgi organization 60.020
Cap-GCG34438 gene product from transcript CG34438-RF0.019
CG4771CG4771 gene product from transcript CG4771-RA0.017
TrfTBP-related factor0.016
RpL35Ribosomal protein L350.016
zpgzero population growth0.015
BicCBicaudal C0.014
CG10107CG10107 gene product from transcript CG10107-RA0.014
RpL36Ribosomal protein L360.014
CG12325CG12325 gene product from transcript CG12325-RA0.014
CG11123CG11123 gene product from transcript CG11123-RA0.013
RpL29Ribosomal protein L290.013
Npc1bNiemann-Pick type C-1b0.012
HLH106Helix loop helix protein 1060.012
RpL39Ribosomal protein L390.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TOB1transducer of ERBB2, 10.998
TNRC6Atrinucleotide repeat containing 6A0.989
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.981
DICER1dicer 1, ribonuclease type III0.967
EIF4A3eukaryotic translation initiation factor 4A30.957
BTG1B-cell translocation gene 1, anti-proliferative0.927
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.852
SRRM1serine/arginine repetitive matrix 10.812
PABPC1poly(A) binding protein, cytoplasmic 10.794
TNRC6Ctrinucleotide repeat containing 6C0.788
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.764
EIF2C1eukaryotic translation initiation factor 2C, 10.751
BTG2BTG family, member 20.690
CNOT7CCR4-NOT transcription complex, subunit 70.656
CNOT8CCR4-NOT transcription complex, subunit 80.643
EIF2C4eukaryotic translation initiation factor 2C, 40.613
CPEB4cytoplasmic polyadenylation element binding protein 40.507
RNPS1RNA binding protein S1, serine-rich domain0.495
CTR9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.465
EIF2C3eukaryotic translation initiation factor 2C, 30.426
EIF4G1eukaryotic translation initiation factor 4 gamma, 10.407
SRPK1SRSF protein kinase 10.367
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.348
SF3A2splicing factor 3a, subunit 2, 66kDa0.309
TNRC6Btrinucleotide repeat containing 6B0.269
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.259
TCEA1transcription elongation factor A (SII), 10.240
CNOT6CCR4-NOT transcription complex, subunit 60.230
SF3B3splicing factor 3b, subunit 3, 130kDa0.212
JUNBjun B proto-oncogene0.184
CNOT6LCCR4-NOT transcription complex, subunit 6-like0.171
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.148
IKIK cytokine, down-regulator of HLA II0.120
SF3B2splicing factor 3b, subunit 2, 145kDa0.101
EIF2C2eukaryotic translation initiation factor 2C, 20.098
PNRC1proline-rich nuclear receptor coactivator 10.094
GSPT1G1 to S phase transition 10.085
USP10ubiquitin specific peptidase 100.080
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.076
U2AF1U2 small nuclear RNA auxiliary factor 10.075
CPEB3cytoplasmic polyadenylation element binding protein 30.070
NR4A2nuclear receptor subfamily 4, group A, member 20.068
IER2immediate early response 20.064
SF1splicing factor 10.061
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.059
CNOT1CCR4-NOT transcription complex, subunit 10.057
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.055
PRKD2protein kinase D20.052
DDX56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.051
SART1squamous cell carcinoma antigen recognized by T cells0.050
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.050
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.049
FUSfused in sarcoma0.048
FOSFBJ murine osteosarcoma viral oncogene homolog0.046
CDK2cyclin-dependent kinase 20.042
PCBP1poly(rC) binding protein 10.040
PCBP2poly(rC) binding protein 20.040
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.039
PRPF8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)0.038
HDAC7histone deacetylase 70.038
JUNDjun D proto-oncogene0.037
NFAT5nuclear factor of activated T-cells 5, tonicity-responsive0.035
G3BP1GTPase activating protein (SH3 domain) binding protein 10.035
RBM10RNA binding motif protein 100.034
KLF6Kruppel-like factor 60.034
RBM8ARNA binding motif protein 8A0.032
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.028
TOB2transducer of ERBB2, 20.027
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.027
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.027
WDR61WD repeat domain 610.027
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.026
SRPK2SRSF protein kinase 20.025
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.024
CCNE1cyclin E10.023
HNRNPMheterogeneous nuclear ribonucleoprotein M0.023
SOBPsine oculis binding protein homolog (Drosophila)0.022
PAIP2poly(A) binding protein interacting protein 20.021
CSRNP1cysteine-serine-rich nuclear protein 10.021
IPO8importin 80.020
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.020
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.019
MFAP1microfibrillar-associated protein 10.019
CLK2CDC-like kinase 20.019
DUSP1dual specificity phosphatase 10.018
PABPN1poly(A) binding protein, nuclear 10.017
E2F1E2F transcription factor 10.017
FOSL2FOS-like antigen 20.017
BCAS2breast carcinoma amplified sequence 20.017
CHTOPchromatin target of PRMT10.017
AFF4AF4/FMR2 family, member 40.017
SF3A1splicing factor 3a, subunit 1, 120kDa0.016
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.016
ACIN1apoptotic chromatin condensation inducer 10.015
HSPA4heat shock 70kDa protein 40.015
CTNNBL1catenin, beta like 10.015
CHERPcalcium homeostasis endoplasmic reticulum protein0.015
DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 10.015
KLF4Kruppel-like factor 4 (gut)0.015
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.014
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
SetSET nuclear oncogene0.483
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.458
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.394
Ptmaprothymosin alpha0.321
Dusp1dual specificity phosphatase 10.260
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.230
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.215
Srsf6serine/arginine-rich splicing factor 60.166
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.152
Ptges3prostaglandin E synthase 3 (cytosolic)0.148
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.135
Fusfusion, derived from t(12;16) malignant liposarcoma (human)0.135
Npm1nucleophosmin 10.125
Ranbp1RAN binding protein 10.118
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.117
Srsf3serine/arginine-rich splicing factor 30.112
Srsf2serine/arginine-rich splicing factor 20.100
Neurl1aneuralized homolog 1A (Drosophila)0.096
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.092
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.091
Prmt1protein arginine N-methyltransferase 10.076
Srsf1serine/arginine-rich splicing factor 10.067
Srsf9serine/arginine-rich splicing factor 90.065
Anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.064
Nap1l1nucleosome assembly protein 1-like 10.063
JunbJun-B oncogene0.062
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.061
Trim32tripartite motif-containing 320.061
Rbm8aRNA binding motif protein 8a0.061
Hmgb1high mobility group box 10.055
Cct2chaperonin containing Tcp1, subunit 2 (beta)0.049
Btg1B-cell translocation gene 1, anti-proliferative0.047
FosFBJ osteosarcoma oncogene0.044
Brd4bromodomain containing 40.044
U2af1U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 10.044
Ewsr1Ewing sarcoma breakpoint region 10.044
Pabpn1poly(A) binding protein, nuclear 10.040
Tcerg1transcription elongation regulator 1 (CA150)0.040
Srsf7serine/arginine-rich splicing factor 70.039
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.036
Cdk4cyclin-dependent kinase 40.036
Anp32eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.035
Thoc4THO complex 40.034
Zfp830zinc finger protein 8300.034
Ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.034
2410002F23RikRIKEN cDNA 2410002F23 gene0.033
Pcbp1poly(rC) binding protein 10.032
Tbx10T-box 100.031
Klf6Kruppel-like factor 60.031
2500003M10RikRIKEN cDNA 2500003M10 gene0.031
Rbm3RNA binding motif protein 30.031
Bptfbromodomain PHD finger transcription factor0.030
G3bp1Ras-GTPase-activating protein SH3-domain binding protein 10.030
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.030
Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B10.030
Zfp36zinc finger protein 360.030
Hivep1human immunodeficiency virus type I enhancer binding protein 10.029
H3f3bH3 histone, family 3B0.029
Tnrc6btrinucleotide repeat containing 6b0.029
Rrs1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.027
Mafkv-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)0.025
JunJun oncogene0.025
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.025
Lamp3lysosomal-associated membrane protein 30.024
Eif2c2eukaryotic translation initiation factor 2C, 20.024
Ier2immediate early response 20.024
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.024
Srsf11serine/arginine-rich splicing factor 110.021
Hmx3H6 homeobox 30.020
Eif4a1eukaryotic translation initiation factor 4A10.020
Pcnaproliferating cell nuclear antigen0.020
Nononon-POU-domain-containing, octamer binding protein0.020
Matr3matrin 30.020
Brd2bromodomain containing 20.018
Nr4a1nuclear receptor subfamily 4, group A, member 10.017
Cpeb2cytoplasmic polyadenylation element binding protein 20.017
Btg2B-cell translocation gene 2, anti-proliferative0.017
Taf1dTATA box binding protein (Tbp)-associated factor, RNA polymerase I, D0.017
Rnps1ribonucleic acid binding protein S10.016
Tuba1btubulin, alpha 1B0.016
Eif5aeukaryotic translation initiation factor 5A0.016
Tfdp1transcription factor Dp 10.015
Pabpc1poly(A) binding protein, cytoplasmic 10.015
Cnot6CCR4-NOT transcription complex, subunit 60.015
Csdacold shock domain protein A0.015
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.015
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.014
Snx13sorting nexin 130.014
Nop56NOP56 ribonucleoprotein homolog (yeast)0.014
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.014
Hspa4heat shock protein 40.014
Hnrnpa0heterogeneous nuclear ribonucleoprotein A00.014
Gar1GAR1 ribonucleoprotein homolog (yeast)0.014
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.014
Rbbp7retinoblastoma binding protein 70.014
Ctbp1C-terminal binding protein 10.013
Cbx3chromobox homolog 3 (Drosophila HP1 gamma)0.013
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
FosFBJ osteosarcoma oncogene0.408
Junbjun B proto-oncogene0.164
Dusp1dual specificity phosphatase 10.117
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.079
Btg2BTG family, member 20.059
Zfp36zinc finger protein 360.044
Ube2cubiquitin-conjugating enzyme E2C0.036
Pttg1pituitary tumor-transforming 10.034
Mafkv-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)0.034
Nr4a1nuclear receptor subfamily 4, group A, member 10.033
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.029
Csrnp1cysteine-serine-rich nuclear protein 10.028
Kifc1kinesin family member C10.027
Atf3activating transcription factor 30.024
JunJun oncogene0.024
Traf4af1TRAF4 associated factor 10.024
Rrm2ribonucleotide reductase M20.024
Ubbubiquitin B0.022
LOC689399hypothetical protein LOC6893990.021
Cdkn3cyclin-dependent kinase inhibitor 30.019
Cdca3cell division cycle associated 30.019
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.019
Errfi1ERBB receptor feedback inhibitor 10.017
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.016
Cdk1cyclin-dependent kinase 10.016
Ccnb1cyclin B10.016
Hmmrhyaluronan mediated motility receptor (RHAMM)0.015
Trim28tripartite motif-containing 280.015
Kif22kinesin family member 220.015
Cks2CDC28 protein kinase regulatory subunit 20.014
Acin1apoptotic chromatin condensation inducer 10.013
Tk1thymidine kinase 1, soluble0.013
Egr1early growth response 10.013
Racgap1Rac GTPase-activating protein 10.013
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.012
Cdca7cell division cycle associated 70.011
Akap8lA kinase (PRKA) anchor protein 8-like0.011
Ier2immediate early response 20.011
Kif2ckinesin family member 2C0.011
Sf3a3splicing factor 3a, subunit 30.010
Tp53tumor protein p530.010
Klf4Kruppel-like factor 4 (gut)0.010
Plk1polo-like kinase 1 (Drosophila)0.010