The network for 'regulation of protein modification process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein modification process

Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

NameDescriptionProbabilityFunc Analog Organism
SIC1Sic1p0.925
PIL1Pil1p0.903
NBP2Nbp2p0.831
BCK1Bck1p0.775
CLB5Clb5p0.702
CTR9Ctr9p0.700
CKS1Cks1p0.677
RTF1Rtf1p0.618
PHO85Pho85p0.593
CDC28Cdc28p0.583
PBS2Pbs2p0.534
CKA1Cka1p0.527
SSK2Ssk2p0.520
CLB3Clb3p0.513
GCN5Gcn5p0.509
SSK1Ssk1p0.458
PSR2Psr2p0.416
SHO1Sho1p0.403
STE4Ste4p0.402
SPT16Spt16p0.401
GIN4Gin4p0.396
CLB6Clb6p0.392
HSL1Hsl1p0.376
STE7Ste7p0.374
CLN1Cln1p0.370
BCK2Bck2p0.369
SIS1Sis1p0.353
FUS3Fus3p0.329
CDC12Cdc12p0.324
BMH1Bmh1p0.321
CKB1Ckb1p0.317
SSA2Ssa2p0.299
STE20Ste20p0.287
SSA3Ssa3p0.278
DAS1Das1p0.275
SLX8Slx8p0.269
RAD53Rad53p0.265
CLB1Clb1p0.264
GLG2Glg2p0.264
DIG1Dig1p0.248
SPT6Spt6p0.248
MSG5Msg5p0.239
BOI1Boi1p0.236
MPS1Mps1p0.232
SWI4Swi4p0.227
KAR2Kar2p0.226
PTC2Ptc2p0.224
HOP1Hop1p0.221
CDC11Cdc11p0.219
YDJ1Ydj1p0.213
CDC55Cdc55p0.210
CLN2Cln2p0.205
ELP4Elp4p0.203
DBF2Dbf2p0.196
AHA1Aha1p0.194
RTT109Rtt109p0.191
MYO5Myo5p0.183
HSP42Hsp42p0.181
SSK22Ssk22p0.176
STE11Ste11p0.176
TCP1Tcp1p0.175
PHO81Pho81p0.175
SLT2Slt2p0.174
STE5Ste5p0.172
GSY1Gsy1p0.163
KEL3Kel3p0.161
GLC7Glc7p0.160
YGR126Whypothetical protein0.159
HCR1Hcr1p0.155
TRA1Tra1p0.155
CDC6Cdc6p0.153
APC5Apc5p0.152
MKS1Mks1p0.150
CLB2Clb2p0.149
BMH2Bmh2p0.148
POM152Pom152p0.145
HIR1Hir1p0.145
PPH22Pph22p0.141
SHP1Shp1p0.140
NPL3Npl3p0.140
HOG1Hog1p0.139
NET1Net1p0.138
RPN2Rpn2p0.138
DEG1Deg1p0.135
MUB1Mub1p0.133
TPS1Tps1p0.126
VPS72Vps72p0.126
ARX1Arx1p0.126
CDC4Cdc4p0.124
EIS1Eis1p0.124
YPD1Ypd1p0.122
MEC1Mec1p0.120
SDS22Sds22p0.120
AHP1Ahp1p0.120
SEC7Sec7p0.119
IME2Ime2p0.117
CRZ1Crz1p0.117
TOR1Tor1p0.115
SMC3Smc3p0.115
ATG21Atg21p0.114
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
glp-1Protein GLP-10.026
mpk-1Protein MPK-10.025
unc-73Protein UNC-730.025
ptr-2Protein PTR-20.023
CELE_F54D5.5Protein F54D5.50.022
vab-3Protein VAB-30.021
tps-1Protein TPS-10.021
lin-7Protein LIN-70.020
unc-40Protein UNC-400.020
nlg-1Protein NLG-10.020
par-3Protein PAR-30.019
egl-27Protein EGL-270.018
par-5Protein PAR-50.018
sma-6Protein SMA-60.018
sur-2Protein SUR-20.018
atn-1Protein ATN-10.017
smp-1Protein SMP-10.017
CELE_C17E4.6Protein C17E4.60.017
mec-2Protein MEC-20.017
exc-5Protein EXC-50.017
dnc-2Protein DNC-20.017
xpo-1Protein XPO-10.017
cdl-1Protein CDL-10.016
nhr-34Protein NHR-340.016
unc-9Protein UNC-90.016
daf-1Protein DAF-10.016
hum-6Protein HUM-60.016
sli-1Protein SLI-10.016
egl-18Protein EGL-180.016
unc-6Protein UNC-60.016
asb-1Protein ASB-10.015
K08E3.5Protein K08E3.50.015
exoc-7Protein EXOC-70.015
mbk-2Protein MBK-20.015
unc-43Protein UNC-430.015
unc-7Protein UNC-70.015
mel-26Protein MEL-260.015
egg-6Protein EGG-60.014
brp-1Protein BRP-10.014
atg-2Protein ATG-20.014
F42C5.9Protein F42C5.90.014
K10D6.4Protein K10D6.40.014
sas-5Protein SAS-50.014
sax-3Protein SAX-30.014
patr-1Protein PATR-10.014
Y55D5A.1Protein Y55D5A.10.014
lin-25Protein LIN-250.014
hda-3Protein HDA-30.014
daf-3Protein DAF-30.014
unc-32Protein UNC-320.014
rhgf-2Protein RHGF-20.014
zyg-8Protein ZYG-80.014
T28D9.4Protein T28D9.40.014
lin-11Protein LIN-110.014
unc-52Protein UNC-520.014
daf-6Protein DAF-60.014
imb-2Protein IMB-20.014
plc-3Protein PLC-30.014
egl-36Protein EGL-360.014
nhr-6Protein NHR-60.014
vps-33.2Protein VPS-33.20.013
zwl-1Protein ZWL-10.013
hil-2Protein HIL-20.013
ida-1Protein IDA-10.013
agl-1Protein AGL-10.013
frm-4Protein FRM-40.013
spc-1Protein SPC-10.013
R07E4.5Protein R07E4.50.013
B0035.6Protein B0035.60.013
wnk-1Protein WNK-10.013
hsr-9Protein HSR-90.013
cam-1Protein CAM-10.013
hda-1Protein HDA-10.013
C07H6.4Protein C07H6.40.013
athp-1Protein ATHP-10.013
ain-2Protein AIN-20.013
rpt-2Protein RPT-20.013
mig-38Protein MIG-380.013
lag-1Protein LAG-10.013
daf-5Protein DAF-50.013
nipi-3Protein NIPI-30.013
rad-51Protein RAD-510.013
ksr-1Protein KSR-10.013
sax-7Protein SAX-70.013
T05F1.2Protein T05F1.20.013
lin-1Protein LIN-10.013
unc-53Protein UNC-530.013
let-711Protein LET-7110.013
eps-8Protein EPS-80.013
F55F8.9Protein F55F8.90.012
ran-1Protein RAN-10.012
W05F2.6Protein W05F2.60.012
dsh-2Protein DSH-20.012
unc-86Protein UNC-860.012
tag-307Protein TAG-3070.012
ZK507.6Protein ZK507.60.012
csnk-1Protein CSNK-10.012
kup-1Protein KUP-10.012
pry-1Protein PRY-10.012
spk-1Protein SPK-10.012
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.165
bmp2bbone morphogenetic protein 2b0.158
shhasonic hedgehog a0.131
evx1even-skipped homeobox 10.116
wnt11rwingless-type MMTV integration site family, member 11, related0.101
bmp2abone morphogenetic protein 2a0.085
igf1rbinsulin-like growth factor 1b receptor0.082
tp53tumor protein p530.070
fgfr3fibroblast growth factor receptor 30.070
pou5f1POU domain, class 5, transcription factor 10.063
cx43connexin 430.061
fzd7afrizzled homolog 7a0.061
sall1asal-like 1a (Drosophila)0.060
notch3notch homolog 30.059
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.058
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.055
gmnngeminin, DNA replication inhibitor0.054
spry4sprouty (Drosophila) homolog 40.054
wnt2bbwingless-type MMTV integration site family, member 2Bb0.053
psen1presenilin 10.053
wnt1wingless-type MMTV integration site family, member 10.053
mpxmyeloid-specific peroxidase0.052
wnt4awingless-type MMTV integration site family, member 4a0.052
rad21RAD21 homolog (S. pombe)0.051
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.046
sox11aSRY-box containing gene 11a0.044
vedventrally expressed dharma/bozozok antagonist0.043
dusp6dual specificity phosphatase 60.043
wlswntless homolog (Drosophila)0.039
per3period homolog 3 (Drosophila)0.038
foxi1forkhead box I10.037
wnt3awingless-type MMTV integration site family, member 3A0.037
wnt10awingless-type MMTV integration site family, member 10a0.037
nrp2bneuropilin 2b0.035
dag1dystroglycan 10.035
egr1early growth response 10.035
nfe2l2nuclear factor (erythroid-derived 2)-like 20.035
twist1atwist1a0.035
chrna4cholinergic receptor, nicotinic, alpha 40.034
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.034
furinafurin (paired basic amino acid cleaving enzyme) a0.032
disp1dispatched homolog 1 (Drosophila)0.032
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.032
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.032
tcf12transcription factor 120.031
rag1recombination activating gene 10.031
fgfr1bfibroblast growth factor receptor 1b0.030
foxn1forkhead box N10.030
rarabretinoic acid receptor, alpha b0.030
dynlrb1dynein, light chain, roadblock-type 10.029
cmybtranscription factor cmyb0.029
dlddeltaD0.029
ccnb1cyclin B10.027
zbtb4zinc finger and BTB domain containing 40.027
csrnp1bcysteine-serine-rich nuclear protein 1b0.027
id1inhibitor of DNA binding 10.027
tgfb1atransforming growth factor, beta 1a0.026
pkd2polycystic kidney disease 20.026
gro1groucho 10.026
plcg1phospholipase C, gamma 10.026
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.026
lef1lymphocyte enhancer binding factor 10.025
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.025
lcp1lymphocyte cytosolic plastin 10.025
smad9MAD homolog 9 (Drosophila)0.025
smad3bMAD, mothers against decapentaplegic homolog 3b (Drosophila)0.025
mpped2metallophosphoesterase domain containing 20.025
lmx1b.1LIM homeobox transcription factor 1, beta 10.025
largelike-glycosyltransferase0.025
cdc25cell division cycle 25 homolog0.025
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.024
gbx1gastrulation brain homeobox 10.024
wu:fb58e05wu:fb58e050.024
ikzf1IKAROS family zinc finger 1 (Ikaros)0.024
pax6bpaired box gene 6b0.024
axin2axin 2 (conductin, axil)0.023
ntlano tail a0.023
sox11bSRY-box containing gene 11b0.023
fesfeline sarcoma oncogene0.023
si:ch211-173o4.2si:ch211-173o4.20.023
dzip1DAZ interacting protein 10.023
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.022
nanos3nanos homolog 30.022
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.022
twist3twist30.022
plxnb2aplexin b2a0.022
runx2arunt-related transcription factor 2a0.021
csnk1dacasein kinase 1, delta a0.021
hdac4histone deacetylase 40.021
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.021
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.021
six4.3sine oculis homeobox homolog 4.30.021
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.021
ptnpleiotrophin0.020
rbmxRNA binding motif protein, X-linked0.020
myogmyogenin0.020
ighzimmunoglobulin heavy constant zeta0.020
sh3gl1bSH3-domain GRB2-like 1b0.020
gli2bGLI-Kruppel family member GLI2b0.020
nrp1aneuropilin 1a0.020
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
par-1CG8201 gene product from transcript CG8201-RA0.981
Rho1CG8416 gene product from transcript CG8416-RB0.911
Pp1-87BProtein phosphatase 1 at 87B0.883
Akt1CG4006 gene product from transcript CG4006-RA0.818
MadMothers against dpp0.787
PtenCG5671 gene product from transcript CG5671-RB0.786
kaykayak0.773
Rac1CG2248 gene product from transcript CG2248-RA0.766
twstwins0.760
Atg1Autophagy-specific gene 10.742
rlrolled0.739
Rab5Rab-protein 50.734
Vap-33-1CG5014 gene product from transcript CG5014-RB0.691
CkIIalphaCasein kinase II alpha subunit0.688
pucpuckered0.687
G-oalpha47AG protein oalpha 47A0.666
shnschnurri0.658
numbCG3779 gene product from transcript CG3779-RB0.597
drkdownstream of receptor kinase0.595
grogroucho0.572
UbxUltrabithorax0.541
rapretina aberrant in pattern0.539
PknProtein kinase related to protein kinase N0.513
rutrutabaga0.491
kiskismet0.484
saxsaxophone0.475
UbqnUbiquilin0.467
Ras85DRas oncogene at 85D0.464
nmonemo0.458
Cip4CG15015 gene product from transcript CG15015-RA0.458
dcodiscs overgrown0.452
Tsc1CG6147 gene product from transcript CG6147-RA0.450
htlheartless0.434
agoarchipelago0.419
Su(H)Suppressor of Hairless0.398
SaraSmad anchor for receptor activation0.397
E(spl)Enhancer of split0.392
slp1sloppy paired 10.372
EndoGIEndonuclease G inhibitor0.370
InRInsulin-like receptor0.357
eyaeyes absent0.354
dshdishevelled0.353
AblAbl tyrosine kinase0.353
rprreaper0.342
p38bCG7393 gene product from transcript CG7393-RA0.342
bskbasket0.341
mxcmulti sex combs0.341
putpunt0.335
JraJun-related antigen0.329
trctricornered0.329
cgcombgap0.325
srstripe0.325
fzfrizzled0.323
Pi3K92ECG4141 gene product from transcript CG4141-RB0.321
ttvtout-velu0.321
skpACG16983 gene product from transcript CG16983-RD0.318
CG6116CG6116 gene product from transcript CG6116-RA0.310
Nrx-IVNeurexin IV0.308
Dcr-2Dicer-20.301
slmbsupernumerary limbs0.291
Rac2CG8556 gene product from transcript CG8556-RA0.290
rheaCG6831 gene product from transcript CG6831-RA0.285
RhebCG1081 gene product from transcript CG1081-RA0.278
Stat92ESignal-transducer and activator of transcription protein at 92E0.274
chicoCG5686 gene product from transcript CG5686-RB0.274
hipkhomeodomain interacting protein kinase0.268
HLHm7E(spl) region transcript m70.266
Uba1Ubiquitin activating enzyme 10.265
dncdunce0.264
spispitz0.261
DabDisabled0.260
mewmultiple edematous wings0.256
ash2absent, small, or homeotic discs 20.254
CG5794CG5794 gene product from transcript CG5794-RB0.252
mbcmyoblast city0.247
spasspastin0.245
linlines0.242
chbchromosome bows0.234
Src42ASrc oncogene at 42A0.232
CycECyclin E0.227
Arp14DActin-related protein 14D0.223
stcksteamer duck0.221
UtxCG5640 gene product from transcript CG5640-RD0.216
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.214
sogshort gastrulation0.209
CaMKIICalcium/calmodulin-dependent protein kinase II0.208
Applbeta amyloid protein precursor-like0.202
sggshaggy0.196
G-salpha60AG protein salpha 60A0.196
RYBPRing and YY1 Binding Protein0.196
trxtrithorax0.196
StimStromal interaction molecule0.196
enengrailed0.195
rictorrapamycin-insensitive companion of Tor0.194
EgfrEpidermal growth factor receptor0.194
Socs36ESuppressor of cytokine signaling at 36E0.189
phlpole hole0.188
emcextra macrochaetae0.187
scbscab0.186
HLHmgammaE(spl) region transcript mgamma0.181
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Jak2Janus kinase 20.849
JunJun oncogene0.667
Hsph1heat shock 105/110 protein 10.631
S1pr2sphingosine-1-phosphate receptor 20.528
Cxcl2chemokine (C-X-C motif) ligand 20.443
Klf6Kruppel-like factor 60.415
Prkcdprotein kinase C, delta0.406
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.372
Fgfr1Fibroblast growth factor receptor 10.371
Sirpasignal-regulatory protein alpha0.345
Olr1654olfactory receptor 16540.341
Junbjun B proto-oncogene0.338
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.334
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.330
Myo1bmyosin Ib0.330
HrasHarvey rat sarcoma virus oncogene0.327
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.321
Jak1Janus kinase 10.317
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.309
Adarb2adenosine deaminase, RNA-specific, B20.302
Slco2a1solute carrier organic anion transporter family, member 2a10.302
Fgfr2fibroblast growth factor receptor 20.301
Phox2apaired-like homeobox 2a0.289
Ciitaclass II, major histocompatibility complex, transactivator0.285
Mapk14mitogen activated protein kinase 140.283
Prp15proline-rich protein 150.281
Hckhemopoietic cell kinase0.278
Arhgap25Rho GTPase activating protein 250.278
Csf1colony stimulating factor 1 (macrophage)0.274
Tgfbr1transforming growth factor, beta receptor 10.273
Ccl4chemokine (C-C motif) ligand 40.271
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.267
Gna12guanine nucleotide binding protein (G protein) alpha 120.266
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.265
Ube2hubiquitin-conjugating enzyme E2H0.263
Il1r1interleukin 1 receptor, type I0.255
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.255
Vav1vav 1 guanine nucleotide exchange factor0.254
Ptafrplatelet-activating factor receptor0.252
Inpp5dinositol polyphosphate-5-phosphatase D0.251
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.248
Lpllipoprotein lipase0.247
Rbck1RanBP-type and C3HC4-type zinc finger containing 10.243
Robo1roundabout homolog 1 (Drosophila)0.242
Fapfibroblast activation protein, alpha0.240
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.239
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.237
Itgb1integrin, beta 10.235
Fkbp4FK506 binding protein 40.232
Nedd4neural precursor cell expressed, developmentally down-regulated 40.232
Ccnd1cyclin D10.231
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.229
Myo1emyosin IE0.228
Exoc5exocyst complex component 50.225
Syt2synaptotagmin II0.224
Stip1stress-induced phosphoprotein 10.223
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.223
FosFBJ osteosarcoma oncogene0.222
Olr1500olfactory receptor 15000.219
Adora2aadenosine A2a receptor0.218
Irs1insulin receptor substrate 10.217
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.215
Oaz1ornithine decarboxylase antizyme 10.213
Akt1v-akt murine thymoma viral oncogene homolog 10.213
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.210
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.206
Gja1gap junction protein, alpha 10.203
Mapk1mitogen activated protein kinase 10.202
Parp9poly (ADP-ribose) polymerase family, member 90.201
Prkciprotein kinase C, iota0.198
Fosl1fos-like antigen 10.197
Syt8synaptotagmin VIII0.196
Gfra2GDNF family receptor alpha 20.195
Tgfbr2transforming growth factor, beta receptor II0.193
Cmklr1chemokine-like receptor 10.192
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.192
Wdr26WD repeat domain 260.192
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.191
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.188
Atxn1ataxin 10.187
Lyve1lymphatic vessel endothelial hyaluronan receptor 10.187
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.187
NsfN-ethylmaleimide-sensitive factor0.187
Ednrbendothelin receptor type B0.183
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.182
Anxa5annexin A50.182
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.182
Myd88myeloid differentiation primary response gene 880.179
Lnpepleucyl/cystinyl aminopeptidase0.177
Dusp6dual specificity phosphatase 60.176
Anxa2annexin A20.176
Gzmkgranzyme K0.176
Homer1homer homolog 1 (Drosophila)0.175
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.175
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.175
Cx3cr1chemokine (C-X3-C motif) receptor 10.173
Nek9NIMA (never in mitosis gene a)- related kinase 90.170
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.170
Mpeg1macrophage expressed 10.169
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.169