The network for 'membrane lipid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

membrane lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.

NameDescriptionProbabilityFunc Analog Organism
GAB1Gab1p0.994
LAS21Las21p0.969
LAG1Lag1p0.938
LCB2Lcb2p0.914
GAA1Gaa1p0.906
LCB1Lcb1p0.843
LCB3Lcb3p0.722
GPI8Gpi8p0.668
TOR1Tor1p0.659
TOR2Tor2p0.651
SCS7Scs7p0.609
GSF2Gsf2p0.557
GWT1Gwt1p0.530
TSC3Tsc3p0.420
YPK1Ypk1p0.413
SPF1Spf1p0.402
AVO1Avo1p0.366
PTK2Ptk2p0.351
MDS3Mds3p0.333
LAC1Lac1p0.330
ARV1Arv1p0.329
ALG6Alg6p0.318
SEC59Sec59p0.317
ERD2Erd2p0.311
GPI16Gpi16p0.304
CSG2Csg2p0.274
ELO1Elo1p0.263
RET2Ret2p0.248
SAC1Sac1p0.245
YJR015Whypothetical protein0.244
GPI2Gpi2p0.241
TVP38Tvp38p0.215
SEF1Sef1p0.200
BMH1Bmh1p0.196
YLR257Whypothetical protein0.192
MCD4Mcd4p0.189
IFA38Ifa38p0.181
PTM1Ptm1p0.180
LDB16Ldb16p0.176
OST6Ost6p0.175
SAK1Sak1p0.170
NEM1Nem1p0.163
GPI13Gpi13p0.156
RFT1Rft1p0.154
OST1Ost1p0.147
CMK2Cmk2p0.147
TCO89Tco89p0.141
GPI11Gpi11p0.132
PMT1Pmt1p0.128
SLM1Slm1p0.127
GPI17Gpi17p0.124
TVP23Tvp23p0.124
YAR028Whypothetical protein0.121
BCK1Bck1p0.121
RTS1Rts1p0.111
ISC1Isc1p0.109
ALG8Alg8p0.106
AGP1Agp1p0.103
PDR15Pdr15p0.101
YJR012Chypothetical protein0.097
PAM1Pam1p0.093
PFA4Pfa4p0.092
DFG10Dfg10p0.090
VHS1Vhs1p0.089
PRS2Prs2p0.088
MBF1Mbf1p0.087
YIR014Whypothetical protein0.086
CNE1Cne1p0.085
SVP26Svp26p0.083
ERG10Erg10p0.082
TAX4Tax4p0.082
CTR2Ctr2p0.080
KSP1Ksp1p0.080
CSH1Csh1p0.080
PPQ1Ppq1p0.080
DIE2Die2p0.079
ERG4Erg4p0.079
IPT1Ipt1p0.078
CHS7Chs7p0.077
VMA11Vma11p0.075
YBR235Whypothetical protein0.075
KOG1Kog1p0.074
FPK1Fpk1p0.073
MKK1Mkk1p0.073
LHS1Lhs1p0.072
NEO1Neo1p0.070
UBP9Ubp9p0.070
GUP1Gup1p0.070
SKS1Sks1p0.070
SKN1Skn1p0.069
YPL260Whypothetical protein0.069
KIN82Kin82p0.068
INP52Inp52p0.068
BET3Bet3p0.068
YHR022Chypothetical protein0.068
FEN1Fen1p0.068
HAL5Hal5p0.068
SFT1Sft1p0.066
YHR080Chypothetical protein0.066
SIP1Sip1p0.066
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_C27A7.1Protein C27A7.10.045
T22D1.3Protein T22D1.30.032
hmgs-1Protein HMGS-10.028
pmp-1Protein PMP-10.027
elo-2Protein ELO-20.026
prx-3Protein PRX-30.024
C10E2.6Protein C10E2.60.020
tmem-135Protein TMEM-1350.019
gspd-1Protein GSPD-10.016
elo-5Protein ELO-50.015
erm-1Protein ERM-10.015
CELE_T10C6.6Protein T10C6.60.014
C44B7.11Protein C44B7.110.014
elo-6Protein ELO-60.014
ZC328.3Protein ZC328.30.014
nstp-2Protein NSTP-20.014
gob-1Protein GOB-10.014
dhs-7Protein DHS-70.013
CELE_C17C3.1Protein C17C3.10.013
aagr-2Protein AAGR-20.013
sptl-1Protein SPTL-10.012
F12B6.2Protein F12B6.20.012
pes-9Protein PES-90.012
tag-335Protein TAG-3350.012
tre-3Protein TRE-30.012
T21C9.6Protein T21C9.60.011
sur-5Protein SUR-50.011
spon-1Protein SPON-10.011
F28B4.3Protein F28B4.30.011
fard-1Protein FARD-10.011
F09E5.11Protein F09E5.110.010
lron-7Protein LRON-70.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
elovl7bELOVL family member 7, elongation of long chain fatty acids (yeast) b0.896
pitpnaphosphatidylinositol transfer protein, alpha0.292
grhl3grainyhead-like 30.273
c1galt1bcore 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b0.245
LOC564867novel protein similar to LAG1 homolog, ceramide synthase family0.240
vtg7vitellogenin 70.224
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.223
rplp1ribosomal protein, large, P10.189
lass2LAG1 homolog, ceramide synthase 2 (S. cerevisiae)0.182
baiap2l1aBAI1-associated protein 2-like 1a0.172
vtg6vitellogenin 60.170
im:7153558im:71535580.161
hsd17b12bhydroxysteroid (17-beta) dehydrogenase 12b0.158
ssr2signal sequence receptor, beta0.153
fa2hfatty acid 2-hydroxylase0.150
zgc:101565zgc:1015650.147
pomt1protein-O-mannosyltransferase 10.136
esr2bestrogen receptor 2b0.129
gulp1GULP, engulfment adaptor PTB domain containing 10.127
sh3gl1aSH3-domain GRB2-like 1a0.125
lpcat4lysophosphatidylcholine acyltransferase 40.125
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.118
gperG protein-coupled estrogen receptor 10.114
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.107
elovl1aelongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1a0.106
lndc1ly6/neurotoxin domain containing 10.104
lass5LAG1 homolog, ceramide synthase 5 (S. cerevisiae)0.102
hsd17b12ahydroxysteroid (17-beta) dehydrogenase 12a0.099
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.099
ugp2bUDP-glucose pyrophosphorylase 2b0.099
vtg1vitellogenin 10.097
manfmesencephalic astrocyte-derived neurotrophic factor0.097
stk10serine/threonine kinase 100.097
nod2nucleotide-binding oligomerization domain containing 20.096
sec11aSEC11 homolog A (S. cerevisiae)0.094
lppLIM domain containing preferred translocation partner in lipoma0.089
zgc:136359zgc:1363590.089
nadkaNAD kinase a0.089
plce1phospholipase C, epsilon 10.081
spg11spastic paraplegia 110.081
LOC557072caspase recruitment domain-containing protein 11-like0.078
tmem135transmembrane protein 1350.075
vps53vacuolar protein sorting 53 homolog (S. cerevisiae)0.074
pfn1profilin 10.073
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.070
ip6k2inositol hexaphosphate kinase 20.069
LOC100004946transient receptor potential cation channel subfamily M member 4-like0.068
zgc:56280zgc:562800.067
igf2binsulin-like growth factor 2b0.063
pbxip1apre-B-cell leukemia homeobox interacting protein 1a0.062
zgc:64114zgc:641140.060
rnf180ring finger protein 1800.059
xkrxXK, Kell blood group complex subunit-related, X-linked0.058
eomesaeomesodermin homolog a0.058
foxo3aforkhead box O3A0.057
nod1nucleotide-binding oligomerization domain containing 10.057
elovl6lELOVL family member 6, elongation of long chain fatty acids like0.056
sh3bp5laSH3-binding domain protein 5-like, a0.055
uap1UDP-N-acteylglucosamine pyrophosphorylase 10.054
sox21aSRY-box containing gene 21a0.053
cyp17a1cytochrome P450, family 17, subfamily A, polypeptide 10.053
st8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.052
si:ch211-284e13.2si:ch211-284e13.20.052
pgm3phosphoglucomutase 30.052
mapk1mitogen-activated protein kinase 10.051
hprt1lhypoxanthine phosphoribosyltransferase 1, like0.051
zgc:64051zgc:640510.049
timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.049
frybfurry homolog b (Drosophila)0.047
tpm1tropomyosin 1 (alpha)0.047
lysmd1LysM, putative peptidoglycan-binding, domain containing 10.046
alas1aminolevulinate, delta-, synthetase 10.046
fam8a1family with sequence similarity 8, member A10.046
atp2b2ATPase, Ca++ transporting, plasma membrane 20.046
fut9fucosyltransferase 90.045
zgc:77241zgc:772410.044
tptetransmembrane phosphatase with tensin homology0.044
zgc:92313zgc:923130.042
trpc6transient receptor potential cation channel, subfamily C, member 60.041
ift81intraflagellar transport 81 homolog0.041
osbpl7oxysterol binding protein-like 70.041
card9caspase recruitment domain family, member 90.041
ucp2uncoupling protein 20.040
si:dkey-246k9.1si:dkey-246k9.10.039
zgc:163016zgc:1630160.039
rab13RAB13, member RAS oncogene family0.039
elovl7aELOVL family member 7, elongation of long chain fatty acids (yeast) a0.039
ppp1r14aaprotein phosphatase 1, regulatory (inhibitor) subunit 14Aa0.038
ctszcathepsin Z0.038
tnfaip8tumor necrosis factor, alpha-induced protein 80.038
ctsdcathepsin D0.038
elmod2ELMO/CED-12 domain containing 20.038
rtn4areticulon 4a0.038
anxa5bannexin A5b0.038
hprt1hypoxanthine phosphoribosyltransferase 10.038
tsga14testis specific, 140.037
socs3bsuppressor of cytokine signaling 3b0.037
lrmplymphoid-restricted membrane protein0.037
abca12ATP-binding cassette, sub-family A (ABC1), member 120.037
slc8a1bsolute carrier family 8 (sodium/calcium exchanger), member 1b0.037
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GPAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)0.525
NOXA1NADPH oxidase activator 10.339
NUMBnumb homolog (Drosophila)0.299
NCF1neutrophil cytosolic factor 10.189
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.176
PIGTphosphatidylinositol glycan anchor biosynthesis, class T0.165
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.145
LAMP1lysosomal-associated membrane protein 10.125
CCDC115coiled-coil domain containing 1150.123
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.114
TMBIM6transmembrane BAX inhibitor motif containing 60.113
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.107
SURF4surfeit 40.095
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.081
CTGFconnective tissue growth factor0.071
DUSP23dual specificity phosphatase 230.069
C1GALT1C1C1GALT1-specific chaperone 10.066
CASP7caspase 7, apoptosis-related cysteine peptidase0.063
FYNFYN oncogene related to SRC, FGR, YES0.057
MAPTmicrotubule-associated protein tau0.050
DEPTORDEP domain containing MTOR-interacting protein0.048
PDPK13-phosphoinositide dependent protein kinase-10.034
PDK1pyruvate dehydrogenase kinase, isozyme 10.032
BCAP31B-cell receptor-associated protein 310.032
SEP1515 kDa selenoprotein0.031
SH3RF1SH3 domain containing ring finger 10.031
PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 10.029
TSTA3tissue specific transplantation antigen P35B0.029
SLC39A1solute carrier family 39 (zinc transporter), member 10.028
PICK1protein interacting with PRKCA 10.028
PRKCAprotein kinase C, alpha0.028
ZNF71zinc finger protein 710.026
PRKCZprotein kinase C, zeta0.025
NEDD9neural precursor cell expressed, developmentally down-regulated 90.023
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.023
PTK2BPTK2B protein tyrosine kinase 2 beta0.022
KAT2BK(lysine) acetyltransferase 2B0.022
CDCP1CUB domain containing protein 10.022
ELOVL1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 10.022
BRF2BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like0.021
GSSglutathione synthetase0.021
COMMD8COMM domain containing 80.021
ALG3asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)0.021
ATP2C1ATPase, Ca++ transporting, type 2C, member 10.021
SLC35A5solute carrier family 35, member A50.020
LRRK2leucine-rich repeat kinase 20.020
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.020
LLGL2lethal giant larvae homolog 2 (Drosophila)0.020
ATG4CATG4 autophagy related 4 homolog C (S. cerevisiae)0.020
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.020
RICTORRPTOR independent companion of MTOR, complex 20.019
MAPKAP1mitogen-activated protein kinase associated protein 10.019
LLGL1lethal giant larvae homolog 1 (Drosophila)0.018
RHEBRas homolog enriched in brain0.018
LASS2LAG1 homolog, ceramide synthase 20.018
SH2D1ASH2 domain containing 1A0.017
NR1H2nuclear receptor subfamily 1, group H, member 20.017
SIGMAR1sigma non-opioid intracellular receptor 10.016
SNX9sorting nexin 90.016
TSC22D1TSC22 domain family, member 10.015
PIGSphosphatidylinositol glycan anchor biosynthesis, class S0.015
PTPLBprotein tyrosine phosphatase-like (proline instead of catalytic arginine), member b0.015
EXOSC4exosome component 40.015
SOAT1sterol O-acyltransferase 10.014
CBLCCas-Br-M (murine) ecotropic retroviral transforming sequence c0.014
GPR172AG protein-coupled receptor 172A0.014
CDC37cell division cycle 37 homolog (S. cerevisiae)0.013
STXBP3syntaxin binding protein 30.013
TMEM123transmembrane protein 1230.013
CD2CD2 molecule0.013
PRKCBprotein kinase C, beta0.013
GNG10guanine nucleotide binding protein (G protein), gamma 100.013
ALOX12Barachidonate 12-lipoxygenase, 12R type0.012
CYB561D2cytochrome b-561 domain containing 20.012
NFS1NFS1 nitrogen fixation 1 homolog (S. cerevisiae)0.012
TM9SF1transmembrane 9 superfamily member 10.012
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.012
PDCD10programmed cell death 100.012
TMEM165transmembrane protein 1650.012
FYBFYN binding protein0.012
UFM1ubiquitin-fold modifier 10.012
TP73tumor protein p730.012
MTORmechanistic target of rapamycin (serine/threonine kinase)0.011
DCTN1dynactin 10.011
RPTORregulatory associated protein of MTOR, complex 10.011
SLC35B2solute carrier family 35, member B20.011
DEGS1degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)0.011
TEX264testis expressed 2640.011
CHUKconserved helix-loop-helix ubiquitous kinase0.011
CD151CD151 molecule (Raph blood group)0.011
GADD45GIP1growth arrest and DNA-damage-inducible, gamma interacting protein 10.011
EXTL2exostoses (multiple)-like 20.011
PRR5Lproline rich 5 like0.011
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif, 10.011
BNIP2BCL2/adenovirus E1B 19kDa interacting protein 20.011
SNX18sorting nexin 180.011
BAG3BCL2-associated athanogene 30.011
C1DC1D nuclear receptor corepressor0.010
ILKintegrin-linked kinase0.010
FASFas (TNF receptor superfamily, member 6)0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
RictorRPTOR independent companion of MTOR, complex 20.821
Elovl1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 10.761
Ebpphenylalkylamine Ca2+ antagonist (emopamil) binding protein0.758
Mapkap1mitogen-activated protein kinase associated protein 10.703
Bcap31B-cell receptor-associated protein 310.698
Thbs1thrombospondin 10.606
CdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.576
Sptlc2serine palmitoyltransferase, long chain base subunit 20.458
Cyr61cysteine rich protein 610.450
Rptorregulatory associated protein of MTOR, complex 10.449
Dpp7dipeptidylpeptidase 70.411
Ptgesprostaglandin E synthase0.404
Ctgfconnective tissue growth factor0.398
Rperibulose-5-phosphate-3-epimerase0.386
0610031J06RikRIKEN cDNA 0610031J06 gene0.376
Tmem33transmembrane protein 330.335
Inpp5jinositol polyphosphate 5-phosphatase J0.327
Orai1ORAI calcium release-activated calcium modulator 10.308
Pthlhparathyroid hormone-like peptide0.306
Mfsd1major facilitator superfamily domain containing 10.286
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.259
Magmyelin-associated glycoprotein0.244
Ormdl2ORM1-like 2 (S. cerevisiae)0.243
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae)0.233
Acsl5acyl-CoA synthetase long-chain family member 50.226
Atp6v0eATPase, H+ transporting, lysosomal V0 subunit E0.199
Alox5aparachidonate 5-lipoxygenase activating protein0.187
Tpp1tripeptidyl peptidase I0.186
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.183
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.180
Syt3synaptotagmin III0.174
Rab25RAB25, member RAS oncogene family0.173
Tuba8tubulin, alpha 80.171
Tmem9bTMEM9 domain family, member B0.165
Tnctenascin C0.158
Hsd17b12hydroxysteroid (17-beta) dehydrogenase 120.154
Spcs2signal peptidase complex subunit 2 homolog (S. cerevisiae)0.154
Scarb2scavenger receptor class B, member 20.151
0610007P14RikRIKEN cDNA 0610007P14 gene0.150
Ndfip1Nedd4 family interacting protein 10.149
Ldb3LIM domain binding 30.138
BC023829cDNA sequence BC0238290.137
Errfi1ERBB receptor feedback inhibitor 10.135
Mybphmyosin binding protein H0.135
Ctsacathepsin A0.135
AclyATP citrate lyase0.134
Clptm1lCLPTM1-like0.133
Ptgirprostaglandin I receptor (IP)0.133
Pvalbparvalbumin0.131
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.122
Serp1stress-associated endoplasmic reticulum protein 10.121
5730494N06RikRIKEN cDNA 5730494N06 gene0.118
Serpine1serine (or cysteine) peptidase inhibitor, clade E, member 10.117
Hrhairless0.117
Cdsncorneodesmosin0.117
Ighimmunoglobulin heavy chain complex0.115
Cd9CD9 antigen0.115
Anxa4annexin A40.112
Sfrp4secreted frizzled-related protein 40.112
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.109
Atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.108
Erp44endoplasmic reticulum protein 440.108
Soat1sterol O-acyltransferase 10.106
Derl2Der1-like domain family, member 20.105
Lass2LAG1 homolog, ceramide synthase 20.105
Tspan31tetraspanin 310.105
Asah1N-acylsphingosine amidohydrolase 10.104
Gpr133G protein-coupled receptor 1330.102
Dusp1dual specificity phosphatase 10.101
Pttg1ippituitary tumor-transforming 1 interacting protein0.100
Txndc12thioredoxin domain containing 12 (endoplasmic reticulum)0.100
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.099
Slc31a1solute carrier family 31, member 10.097
Ebag9estrogen receptor-binding fragment-associated gene 90.094
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.094
Dpagt1dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)0.093
Tmem40transmembrane protein 400.092
Amotl2angiomotin-like 20.089
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.088
Scg3secretogranin III0.086
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.085
F3coagulation factor III0.085
Cyp51cytochrome P450, family 510.084
Osmroncostatin M receptor0.083
Tcaptitin-cap0.081
Nr4a1nuclear receptor subfamily 4, group A, member 10.080
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.080
Tll1tolloid-like0.078
1600012H06RikRIKEN cDNA 1600012H06 gene0.077
Syt5synaptotagmin V0.076
Ptplad1protein tyrosine phosphatase-like A domain containing 10.076
Scg2secretogranin II0.076
Ngpneutrophilic granule protein0.075
Degs1degenerative spermatocyte homolog 1 (Drosophila)0.074
Polr3kpolymerase (RNA) III (DNA directed) polypeptide K0.074
Arl6ip1ADP-ribosylation factor-like 6 interacting protein 10.074
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.073
Itga2integrin alpha 20.073
Tm9sf2transmembrane 9 superfamily member 20.072
Lpcat3lysophosphatidylcholine acyltransferase 30.070
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism