The network for 'positive regulation of bone remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of bone remodeling

Any process that activates or increases the frequency, rate or extent of bone remodeling.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CASP8caspase 8, apoptosis-related cysteine peptidase0.074
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.044
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.038
UBASH3Bubiquitin associated and SH3 domain containing B0.021
ITKIL2-inducible T-cell kinase0.016
SH3BP4SH3-domain binding protein 40.015
FASFas (TNF receptor superfamily, member 6)0.015
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.013
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.012
CFLARCASP8 and FADD-like apoptosis regulator0.010
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ltbp2latent transforming growth factor beta binding protein 20.729
Col1a1collagen, type I, alpha 10.432
Tgfbr2transforming growth factor, beta receptor II0.398
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.340
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.316
Hspg2perlecan (heparan sulfate proteoglycan 2)0.307
Cav1caveolin 1, caveolae protein0.302
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.278
Agtr2angiotensin II receptor, type 20.272
Itgb3integrin beta 30.264
Cd22CD22 antigen0.244
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.227
Fbn1fibrillin 10.222
Gja1gap junction protein, alpha 10.218
Hic1hypermethylated in cancer 10.198
Jag1jagged 10.192
Csf1colony stimulating factor 1 (macrophage)0.159
Mmp2matrix metallopeptidase 20.146
Loxlysyl oxidase0.145
Adam15a disintegrin and metallopeptidase domain 15 (metargidin)0.141
Igkimmunoglobulin kappa chain complex0.119
Tgfb2transforming growth factor, beta 20.110
Iduaiduronidase, alpha-L-0.102
Agtr1aangiotensin II receptor, type 1a0.102
Xcr1chemokine (C motif) receptor 10.100
Foxc2forkhead box C20.093
Ldlrlow density lipoprotein receptor0.091
Bmp1bone morphogenetic protein 10.090
Col6a2collagen, type VI, alpha 20.087
Cx3cr1chemokine (C-X3-C) receptor 10.083
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.082
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.079
Nos3nitric oxide synthase 3, endothelial cell0.078
Thbs2thrombospondin 20.076
Acvrl1activin A receptor, type II-like 10.075
Ngpneutrophilic granule protein0.072
Mc5rmelanocortin 5 receptor0.068
Itgb1integrin beta 1 (fibronectin receptor beta)0.067
Pax1paired box gene 10.065
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.059
Col6a1collagen, type VI, alpha 10.058
Pdgfbplatelet derived growth factor, B polypeptide0.058
Ciitaclass II transactivator0.052
Mcammelanoma cell adhesion molecule0.051
Aebp1AE binding protein 10.050
Adam17a disintegrin and metallopeptidase domain 170.050
Ctskcathepsin K0.050
Tnks1bp1tankyrase 1 binding protein 10.050
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.049
Lrp5low density lipoprotein receptor-related protein 50.049
Ppargc1bperoxisome proliferative activated receptor, gamma, coactivator 1 beta0.049
Egfrepidermal growth factor receptor0.049
Jupjunction plakoglobin0.047
Wisp2WNT1 inducible signaling pathway protein 20.047
Creb3l1cAMP responsive element binding protein 3-like 10.046
Prg3proteoglycan 30.045
Klra5killer cell lectin-like receptor, subfamily A, member 50.044
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.042
Gp5glycoprotein 5 (platelet)0.042
Tgfb1i1transforming growth factor beta 1 induced transcript 10.041
Col6a3collagen, type VI, alpha 30.041
C1qtnf1C1q and tumor necrosis factor related protein 10.040
Vangl2vang-like 2 (van gogh, Drosophila)0.040
Wwp1WW domain containing E3 ubiquitin protein ligase 10.040
Fn1fibronectin 10.039
Axin1axin 10.038
Mageb3melanoma antigen, family B, 30.037
Vipr2vasoactive intestinal peptide receptor 20.037
Ppargperoxisome proliferator activated receptor gamma0.037
Lrp1low density lipoprotein receptor-related protein 10.037
Fut7fucosyltransferase 70.035
Sod3superoxide dismutase 3, extracellular0.035
Apoeapolipoprotein E0.035
Prlrprolactin receptor0.035
Col5a1collagen, type V, alpha 10.035
Tgfbr1transforming growth factor, beta receptor I0.035
Col1a2collagen, type I, alpha 20.035
Lama5laminin, alpha 50.034
Lamc2laminin, gamma 20.034
Npy1rneuropeptide Y receptor Y10.034
Gna15guanine nucleotide binding protein, alpha 150.034
Ccr1l1chemokine (C-C motif) receptor 1-like 10.033
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.033
Tenc1tensin like C1 domain-containing phosphatase0.033
Slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.032
Epha6Eph receptor A60.032
Tgfb1transforming growth factor, beta 10.031
Itga5integrin alpha 5 (fibronectin receptor alpha)0.030
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.030
Starsteroidogenic acute regulatory protein0.030
Ddr2discoidin domain receptor family, member 20.029
Latlinker for activation of T cells0.029
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.029
C5ar1complement component 5a receptor 10.028
Hbegfheparin-binding EGF-like growth factor0.028
Igjimmunoglobulin joining chain0.027
Cd180CD180 antigen0.027
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism