The network for 'glycerophospholipid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glycerophospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.

NameDescriptionProbabilityFunc Analog Organism
GPI8Gpi8p0.941
LAS21Las21p0.846
GPI17Gpi17p0.801
GAA1Gaa1p0.764
CDS1Cds1p0.741
GAB1Gab1p0.657
PSD1Psd1p0.607
MDM35Mdm35p0.599
TGL1Tgl1p0.578
PSD2Psd2p0.517
GPI16Gpi16p0.481
SPF1Spf1p0.466
EHT1Eht1p0.465
PER1Per1p0.405
PDR17Pdr17p0.371
MDM32Mdm32p0.354
YJR015Whypothetical protein0.350
FAT1Fat1p0.349
GLO3Glo3p0.309
GWT1Gwt1p0.297
ARV1Arv1p0.285
GPI2Gpi2p0.276
INO2Ino2p0.249
RFT1Rft1p0.227
PLB2Plb2p0.223
SLC1Slc1p0.220
ROT2Rot2p0.201
CHO1Cho1p0.199
YGR205Whypothetical protein0.196
YME1Yme1p0.192
SAM2Sam2p0.192
ITR1Itr1p0.184
IZH4Izh4p0.178
DIE2Die2p0.177
SPT14Spt14p0.176
CHO2Cho2p0.168
PFA4Pfa4p0.164
FAB1Fab1p0.163
MID1Mid1p0.150
TSC10Tsc10p0.145
UPS3Ups3p0.143
MDS3Mds3p0.143
SUR2Sur2p0.133
ASI2Asi2p0.132
CNA1Cna1p0.123
GLN3Gln3p0.123
CDC50Cdc50p0.121
ALG6Alg6p0.118
PTC7Ptc7p0.114
CTI6Cti6p0.113
YNL035Chypothetical protein0.109
MON2Mon2p0.107
YOL107Whypothetical protein0.106
RMR1Rmr1p0.106
YBR063Chypothetical protein0.104
HTD2Htd2p0.104
GUP1Gup1p0.102
GPI13Gpi13p0.102
INO1Ino1p0.100
YGL082Whypothetical protein0.099
GOT1Got1p0.099
YAP7Yap7p0.098
ELO1Elo1p0.098
OPI3Opi3p0.096
ERV29Erv29p0.096
YLR036Chypothetical protein0.094
PFA5Pfa5p0.094
PMT3Pmt3p0.093
MCD4Mcd4p0.092
IMD2Imd2p0.092
AGE1Age1p0.091
NEM1Nem1p0.091
MOB2Mob2p0.091
FSH1Fsh1p0.091
MDM34Mdm34p0.090
ECM9Ecm9p0.090
RBD2Rbd2p0.089
GCS1Gcs1p0.087
YIM1Yim1p0.087
OPI1Opi1p0.086
YJU3Yju3p0.084
ERG5Erg5p0.084
SSL1Ssl1p0.082
MMF1Mmf1p0.080
YHR177Whypothetical protein0.079
RXT3Rxt3p0.079
PRS2Prs2p0.078
YHB1Yhb1p0.074
RTS1Rts1p0.072
AVT4Avt4p0.071
SCT1Sct1p0.071
YNL108Chypothetical protein0.070
RER2Rer2p0.070
GPI19Gpi19p0.068
SVP26Svp26p0.068
SFB3Sfb3p0.068
YDL133Whypothetical protein0.067
TVP38Tvp38p0.065
YJR012Chypothetical protein0.065
DGK1Dgk1p0.064
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
disp1dispatched homolog 1 (Drosophila)0.081
smyd2bSET and MYND domain containing 2b0.057
nkx2.3NK2 transcription factor related 30.057
fabp11afatty acid binding protein 11a0.047
ppargperoxisome proliferator activated receptor gamma0.036
stc1lstanniocalcin 1, like0.035
si:dkeyp-50f5.1si:dkeyp-50f5.10.033
chmchoroideremia0.031
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.029
ak4adenylate kinase 40.029
LOC569128hypothetical protein LOC5691280.023
mstnamyostatin a0.023
pdgfabplatelet derived growth factor alpha b0.023
azin1bantizyme inhibitor 1b0.022
mitd1MIT, microtubule interacting and transport, domain containing 10.022
katnb1katanin p80 (WD repeat containing) subunit B 10.022
rnf180ring finger protein 1800.021
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.021
igfbp7insulin-like growth factor binding protein 70.021
get4golgi to ER traffic protein 4 homolog (S. cerevisiae)0.020
adipor1badiponectin receptor 1b0.020
sec11aSEC11 homolog A (S. cerevisiae)0.019
ntn1anetrin 1a0.019
smyd1aSET and MYND domain containing 1a0.019
myh11amyosin, heavy polypeptide 11, smooth muscle a0.019
dmrt2bdoublesex and mab-3 related transcription factor 2b0.019
smoc2secreted modular calcium binding protein 20.018
alpalkaline phosphatase0.018
pvrl1apoliovirus receptor-related 1a0.017
lamb1alaminin, beta 1a0.017
trpv6transient receptor potential cation channel, subfamily V, member 60.017
ndfip1Nedd4 family interacting protein 10.017
plp2proteolipid protein 20.017
zgc:92806zgc:928060.017
pck2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.017
phb2prohibitin 20.017
pdgfaaplatelet-derived growth factor alpha a0.016
suclg2succinate-CoA ligase, GDP-forming, beta subunit0.016
brms1breast cancer metastasis-suppressor 10.016
pgrmc1progesterone receptor membrane component 10.016
rcbtb1regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 10.016
rcn1reticulocalbin 1, EF-hand calcium binding domain0.016
bmp2abone morphogenetic protein 2a0.016
fa2hfatty acid 2-hydroxylase0.016
use1unconventional SNARE in the ER 1 homolog (S. cerevisiae)0.016
coq3coenzyme Q3 homolog, methyltransferase (yeast)0.015
ythdf3YTH domain family 30.015
smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.015
si:dkey-228g21.4si:dkey-228g21.40.015
nucb2bnucleobindin 2b0.015
tolliptoll interacting protein0.015
nucb2anucleobindin 2a0.015
si:ch211-160j6.2si:ch211-160j6.20.015
rdh10aretinol dehydrogenase 10a0.015
ap3m1adaptor-related protein complex 3, mu 1 subunit0.015
zgc:110188zgc:1101880.015
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.015
emilin3aelastin microfibril interfacer 3a0.015
pgam1bphosphoglycerate mutase 1b0.015
dclk2doublecortin-like kinase 20.015
emp2epithelial membrane protein 20.014
ptmaaprothymosin, alpha a0.014
kiss1KiSS-1 metastasis-suppressor0.014
ildr2immunoglobulin-like domain containing receptor 20.014
pdia5protein disulfide isomerase family A, member 50.014
vps26blvacuolar protein sorting 26 homolog B, like0.014
klfdKruppel-like factor d0.014
si:dkey-145p14.5si:dkey-145p14.50.014
defbl3defensin, beta-like 30.014
gdap1ganglioside-induced differentiation-associated protein 10.014
fam8a1family with sequence similarity 8, member A10.014
gyg1glycogenin 10.014
bin2bbridging integrator 2b0.014
ck2a2acasein kinase 2 alpha 2a0.014
tyrp1btyrosinase-related protein 1b0.014
bmp2kBMP2 inducible kinase0.013
dcun1d2DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)0.013
asphaspartate beta-hydroxylase0.013
cratbcarnitine O-acetyltransferase b0.013
ptplad1protein tyrosine phosphatase-like A domain containing 10.013
vac14vac14 homolog (S. cerevisiae)0.013
tmem135transmembrane protein 1350.013
ufsp2ufm1-specific peptidase 20.013
zgc:158327zgc:1583270.013
zdhhc3zinc finger, DHHC-type containing 30.013
zgc:92458zgc:924580.013
si:ch211-239j15.4si:ch211-239j15.40.013
znf277zinc finger protein 2770.013
minpp1bmultiple inositol polyphosphate histidine phosphatase, 1b0.012
efemp2EGF-containing fibulin-like extracellular matrix protein 20.012
spam1sperm adhesion molecule 10.012
antxr2aanthrax toxin receptor 2a0.012
copg2coatomer protein complex, subunit gamma 20.012
zgc:77112zgc:771120.012
foxa1forkhead box A10.012
acp5bacid phosphatase 5b, tartrate resistant0.012
sesn3sestrin 30.012
vps53vacuolar protein sorting 53 homolog (S. cerevisiae)0.012
homezhomeodomain leucine zipper gene0.012
ldhalactate dehydrogenase A40.012
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.997
FGFR1fibroblast growth factor receptor 10.837
FGFR2fibroblast growth factor receptor 20.813
GRB2growth factor receptor-bound protein 20.642
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.532
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.480
MPDZmultiple PDZ domain protein0.456
VEGFAvascular endothelial growth factor A0.375
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.369
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.248
ALBalbumin0.246
IRS1insulin receptor substrate 10.213
APOA1apolipoprotein A-I0.184
GPAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)0.179
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.152
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.143
SHC1SHC (Src homology 2 domain containing) transforming protein 10.143
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.137
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.114
NRP1neuropilin 10.114
A2Malpha-2-macroglobulin0.103
HPhaptoglobin0.098
PIGTphosphatidylinositol glycan anchor biosynthesis, class T0.083
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.081
CHMP2Bchromatin modifying protein 2B0.075
SYKspleen tyrosine kinase0.072
NOS1nitric oxide synthase 1 (neuronal)0.068
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.067
PLCG1phospholipase C, gamma 10.063
CMIPc-Maf-inducing protein0.053
APOC1apolipoprotein C-I0.053
APOC3apolipoprotein C-III0.046
UVRAGUV radiation resistance associated gene0.045
CD63CD63 molecule0.044
SHC2SHC (Src homology 2 domain containing) transforming protein 20.043
SH3BP2SH3-domain binding protein 20.042
BLNKB-cell linker0.041
CUTAcutA divalent cation tolerance homolog (E. coli)0.040
PTPN1protein tyrosine phosphatase, non-receptor type 10.039
PGFplacental growth factor0.038
SOS1son of sevenless homolog 1 (Drosophila)0.038
GAB1GRB2-associated binding protein 10.038
BECN1beclin 1, autophagy related0.036
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.035
LCATlecithin-cholesterol acyltransferase0.035
FGF10fibroblast growth factor 100.034
EGFRepidermal growth factor receptor0.031
AXLAXL receptor tyrosine kinase0.031
SPAG9sperm associated antigen 90.031
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.030
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.029
SAR1BSAR1 homolog B (S. cerevisiae)0.029
FGF7fibroblast growth factor 70.029
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.028
FGF1fibroblast growth factor 1 (acidic)0.028
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.028
HMGCR3-hydroxy-3-methylglutaryl-CoA reductase0.027
SLMO2slowmo homolog 2 (Drosophila)0.027
MDFIMyoD family inhibitor0.026
C17orf28chromosome 17 open reading frame 280.026
POLR2Kpolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa0.026
PIKFYVEphosphoinositide kinase, FYVE finger containing0.026
SORBS1sorbin and SH3 domain containing 10.026
SORBS3sorbin and SH3 domain containing 30.026
NME4non-metastatic cells 4, protein expressed in0.026
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.026
SPG20spastic paraplegia 20 (Troyer syndrome)0.025
APOC2apolipoprotein C-II0.025
TLR3toll-like receptor 30.024
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.024
GRB7growth factor receptor-bound protein 70.024
PTPRBprotein tyrosine phosphatase, receptor type, B0.024
RABGGTBRab geranylgeranyltransferase, beta subunit0.024
INO80BINO80 complex subunit B0.024
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.024
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.023
GAB2GRB2-associated binding protein 20.023
DCTN1dynactin 10.023
TSPAN4tetraspanin 40.023
GRB10growth factor receptor-bound protein 100.022
C6orf211chromosome 6 open reading frame 2110.022
PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide0.021
FGAfibrinogen alpha chain0.021
VAV2vav 2 guanine nucleotide exchange factor0.021
IPO11importin 110.021
PIGSphosphatidylinositol glycan anchor biosynthesis, class S0.021
GMFBglia maturation factor, beta0.020
LMF2lipase maturation factor 20.020
TMEM41Btransmembrane protein 41B0.020
SH2B1SH2B adaptor protein 10.020
VAV3vav 3 guanine nucleotide exchange factor0.019
CD28CD28 molecule0.019
APOA2apolipoprotein A-II0.019
ERRFI1ERBB receptor feedback inhibitor 10.019
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.019
LIN7Clin-7 homolog C (C. elegans)0.019
SSTR3somatostatin receptor 30.018
WDTC1WD and tetratricopeptide repeats 10.018
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.018
TTRtransthyretin0.018
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.673
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.667
Pik3cbphosphatidylinositol 3-kinase, catalytic, beta polypeptide0.618
Alox5aparachidonate 5-lipoxygenase activating protein0.590
Ptenphosphatase and tensin homolog0.266
Pik3r3phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)0.201
BlnkB-cell linker0.194
Nfe2l2nuclear factor, erythroid derived 2, like 20.187
CblCasitas B-lineage lymphoma0.177
Gab1growth factor receptor bound protein 2-associated protein 10.171
BtkBruton agammaglobulinemia tyrosine kinase0.162
Pdlim4PDZ and LIM domain 40.161
Irs1insulin receptor substrate 10.152
Tmem38btransmembrane protein 38B0.142
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.126
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.124
Parvgparvin, gamma0.120
Cd40CD40 antigen0.112
Mta1metastasis associated 10.096
Kpna2karyopherin (importin) alpha 20.093
Ep300E1A binding protein p3000.091
Inpp5dinositol polyphosphate-5-phosphatase D0.088
Notch2Notch gene homolog 2 (Drosophila)0.086
Nsun2NOL1/NOP2/Sun domain family member 20.085
Pdgfcplatelet-derived growth factor, C polypeptide0.082
Lig4ligase IV, DNA, ATP-dependent0.074
Ipo5importin 50.071
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.071
Lmf1lipase maturation factor 10.070
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.069
Becn1beclin 1, autophagy related0.068
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.067
Lpllipoprotein lipase0.065
FynFyn proto-oncogene0.064
Orai1ORAI calcium release-activated calcium modulator 10.064
Rhbdf1rhomboid family 1 (Drosophila)0.063
Nbnnibrin0.060
Phc2polyhomeotic-like 2 (Drosophila)0.059
Pcsk1proprotein convertase subtilisin/kexin type 10.059
TcrdT-cell receptor delta chain0.058
Pik3r2phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)0.057
Dsc3desmocollin 30.055
Sh3d19SH3 domain protein D190.053
Hook2hook homolog 2 (Drosophila)0.053
Ptpn13protein tyrosine phosphatase, non-receptor type 130.052
Cd36CD36 antigen0.052
Klk6kallikrein related-peptidase 60.050
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.050
Bcl6B-cell leukemia/lymphoma 60.049
Tmem98transmembrane protein 980.048
Bsgbasigin0.048
Plekhg2pleckstrin homology domain containing, family G (with RhoGef domain) member 20.048
Rab34RAB34, member of RAS oncogene family0.048
Magmyelin-associated glycoprotein0.045
Itsn1intersectin 1 (SH3 domain protein 1A)0.045
Rbp2retinol binding protein 2, cellular0.045
Apoeapolipoprotein E0.044
Dok1docking protein 10.044
Pik3r6phosphoinositide-3-kinase, regulatory subunit 60.043
Fcgr2bFc receptor, IgG, low affinity IIb0.043
Nr3c1nuclear receptor subfamily 3, group C, member 10.043
Trip6thyroid hormone receptor interactor 60.043
Sorbs3sorbin and SH3 domain containing 30.043
Stra6stimulated by retinoic acid gene 60.041
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.041
Fbp2fructose bisphosphatase 20.041
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.041
5730494N06RikRIKEN cDNA 5730494N06 gene0.040
3110056O03RikRIKEN cDNA 3110056O03 gene0.039
Ttrtransthyretin0.039
Padi2peptidyl arginine deiminase, type II0.039
Apobapolipoprotein B0.039
Kifc3kinesin family member C30.038
Lgals2lectin, galactose-binding, soluble 20.038
Tnfaip1tumor necrosis factor, alpha-induced protein 1 (endothelial)0.038
Padi4peptidyl arginine deiminase, type IV0.038
Dok3docking protein 30.037
Lratlecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)0.036
Flnafilamin, alpha0.036
Tnfsf15tumor necrosis factor (ligand) superfamily, member 150.035
Dnm1dynamin 10.035
Prkcdprotein kinase C, delta0.035
Rock2Rho-associated coiled-coil containing protein kinase 20.035
Gad2glutamic acid decarboxylase 20.035
Sod2superoxide dismutase 2, mitochondrial0.034
Tcaptitin-cap0.034
Lasp1LIM and SH3 protein 10.033
Dram2VDNA-damage regulated autophagy modulator 20.033
Tgfbr1transforming growth factor, beta receptor I0.033
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.032
Tcf15transcription factor 150.032
Gjb6gap junction protein, beta 60.032
Sar1bSAR1 gene homolog B (S. cerevisiae)0.032
Fam73bfamily with sequence similarity 73, member B0.031
Dok2docking protein 20.031
Pdcd6ipprogrammed cell death 6 interacting protein0.031
Ighimmunoglobulin heavy chain complex0.030
Dnajb5DnaJ (Hsp40) homolog, subfamily B, member 50.030
Phlda3pleckstrin homology-like domain, family A, member 30.030
Anapc7anaphase promoting complex subunit 70.030
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Irs1insulin receptor substrate 10.015
Alas2aminolevulinate, delta-, synthase 20.011
Hba-a2hemoglobin alpha, adult chain 20.011
Padi3peptidyl arginine deiminase, type III0.011
Phkg1phosphorylase kinase, gamma 10.011
Man1a2mannosidase, alpha, class 1A, member 20.011
Klrb1akiller cell lectin-like receptor subfamily B, member 1A0.010