The network for 'dna integrity checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dna integrity checkpoint

A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.

NameDescriptionProbabilityFunc Analog Organism
RAD53Rad53p0.882
GLC7Glc7p0.875
POL30Pol30p0.599
MRC1Mrc1p0.396
RPO26Rpo26p0.387
GBP2Gbp2p0.371
BUB3Bub3p0.299
DPB11Dpb11p0.290
DDC1Ddc1p0.260
TOR1Tor1p0.258
CDC20Cdc20p0.215
MEC1Mec1p0.211
RAD17Rad17p0.210
RGC1Rgc1p0.178
RAD27Rad27p0.165
SNF1Snf1p0.159
CWC2Cwc2p0.146
CSM3Csm3p0.142
TOF1Tof1p0.135
TIP41Tip41p0.132
CAK1Cak1p0.129
SCS2Scs2p0.124
SPT5Spt5p0.121
BIM1Bim1p0.117
RPB3Rpb3p0.116
MCM6Mcm6p0.116
PTK2Ptk2p0.114
DBF4Dbf4p0.113
RAD18Rad18p0.110
RPB10Rpb10p0.108
DUN1Dun1p0.108
PLC1Plc1p0.108
MCM4Mcm4p0.107
MCM2Mcm2p0.105
PPH21Pph21p0.099
PPH22Pph22p0.098
SLD3Sld3p0.093
HTA2Hta2p0.090
DPB2Dpb2p0.089
NAT1Nat1p0.087
HRK1Hrk1p0.085
PPZ1Ppz1p0.083
POL3Pol3p0.082
PSF1Psf1p0.078
MAD2Mad2p0.074
PAM1Pam1p0.073
MPT5Mpt5p0.073
HHT2Hht2p0.071
SAP4Sap4p0.071
RRD1Rrd1p0.071
MCM5Mcm5p0.069
PEX22Pex22p0.067
RTS1Rts1p0.066
RPB11Rpb11p0.066
CDC37Cdc37p0.065
CTF18Ctf18p0.064
VAC17Vac17p0.064
POL32Pol32p0.063
BSC2Bsc2p0.062
ZIP1Zip1p0.062
MMS22Mms22p0.061
CTF8Ctf8p0.061
RAD52Rad52p0.059
PAP2Pap2p0.058
SDC1Sdc1p0.057
BUB1Bub1p0.056
SRS2Srs2p0.056
DCC1Dcc1p0.053
MUS81Mus81p0.053
SEF1Sef1p0.053
FPK1Fpk1p0.053
HSL1Hsl1p0.052
RAD9Rad9p0.050
KIN82Kin82p0.050
PDS1Pds1p0.050
DSK2Dsk2p0.048
THO2Tho2p0.048
HTB1Htb1p0.048
TCO89Tco89p0.047
SUR1Sur1p0.047
ACM1Acm1p0.047
SWI4Swi4p0.047
VHS1Vhs1p0.046
HDA2Hda2p0.045
CDC6Cdc6p0.045
MAD1Mad1p0.044
MCM10Mcm10p0.043
PDE2Pde2p0.043
BMH1Bmh1p0.043
ELG1Elg1p0.041
RFA2Rfa2p0.040
YNL134Chypothetical protein0.040
MBF1Mbf1p0.040
YLR177Whypothetical protein0.039
LCD1Lcd1p0.039
IME2Ime2p0.039
SLD2Sld2p0.039
PDR15Pdr15p0.038
GAL7Gal7p0.038
ADE17Ade17p0.038
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.128
ccnb1cyclin B10.108
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.062
cul3acullin 3a0.046
snrpd1small nuclear ribonucleoprotein D1 polypeptide0.044
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.041
ccnb2cyclin B20.037
cry3cryptochrome 30.037
per2period homolog 2 (Drosophila)0.037
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.036
zc4h2zinc finger, C4H2 domain containing0.034
plk1polo-like kinase 1 (Drosophila)0.032
skp2S-phase kinase-associated protein 2 (p45)0.032
ccnd1cyclin D10.029
ywhaqatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a0.029
cstf1cleavage stimulation factor, 3' pre-RNA, subunit 10.029
ccna2cyclin A20.026
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.026
npatnuclear protein, ataxia-telangiectasia locus0.026
stmn1bstathmin 1b0.026
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 60.023
tfamtranscription factor A, mitochondrial0.022
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.021
wdr76WD repeat domain 760.021
smc3structural maintenance of chromosomes 30.021
slbpstem-loop binding protein0.020
cand1cullin-associated and neddylation-dissociated 10.020
ddb2damage-specific DNA binding protein 20.019
zff9zinc finger protein 90.018
zgc:55701zgc:557010.018
sass6spindle assembly 6 homolog (C. elegans)0.018
prdm9PR domain containing 90.018
hirip3HIRA interacting protein 30.017
gtdc1glycosyltransferase-like domain containing 10.016
hat1histone acetyltransferase 10.016
sae1SUMO1 activating enzyme subunit 10.016
kpna3karyopherin (importin) alpha 30.015
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.015
brd2abromodomain-containing 2a0.015
ppp4caprotein phosphatase 4 (formerly X), catalytic subunit a0.015
orc6origin recognition complex, subunit 60.015
zgc:56197zgc:561970.014
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.014
ube2g2ubiquitin-conjugating enzyme E2G 20.014
cry5cryptochrome 50.014
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.014
mpped2metallophosphoesterase domain containing 20.013
si:dkey-57a22.11si:dkey-57a22.110.013
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.013
fen1flap structure-specific endonuclease 10.013
rbb4retinoblastoma binding protein 40.013
fzd7afrizzled homolog 7a0.013
rtkn2rhotekin 20.013
otx1borthodenticle homolog 1b0.013
ccnt2acyclin T2a0.013
senp3aSUMO1/sentrin/SMT3 specific peptidase 3a0.013
kif23kinesin family member 230.012
gmnngeminin, DNA replication inhibitor0.012
wdhd1WD repeat and HMG-box DNA binding protein 10.012
clock3clock homolog 3 (mouse)0.012
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.012
wu:fb54a03wu:fb54a030.012
ccnecyclin E0.011
naspnuclear autoantigenic sperm protein (histone-binding)0.011
zgc:55448zgc:554480.011
aggf1angiogenic factor with G patch and FHA domains 10.011
atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.011
lrwd1leucine-rich repeats and WD repeat domain containing 10.011
ptmaaprothymosin, alpha a0.011
zgc:111944zgc:1119440.011
morf4l1mortality factor 4 like 10.011
ppp2r5ebprotein phosphatase 2, regulatory subunit B', epsilon isoform b0.011
zgc:101819zgc:1018190.011
tubgcp2tubulin, gamma complex associated protein 20.011
dnmt1DNA (cytosine-5-)-methyltransferase 10.011
maeamacrophage erythroblast attacher0.011
rrm1ribonucleotide reductase M1 polypeptide0.010
zc3h13zinc finger CCCH-type containing 130.010
wdr18WD repeat domain 180.010
cops3COP9 constitutive photomorphogenic homolog subunit 30.010
aurkbaurora kinase B0.010
smc1alstructural maintenance of chromosomes 1A, like0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
skpACG16983 gene product from transcript CG16983-RD0.967
lokloki0.964
His2AvHistone H2A variant0.922
picpiccolo0.872
Rpd3CG7471 gene product from transcript CG7471-RA0.851
sspsunspot0.850
IswiImitation SWI0.848
eIF4AIIICG7483 gene product from transcript CG7483-RA0.774
spn-Bspindle B0.718
cdc2cCG10498 gene product from transcript CG10498-RC0.710
Caf1Chromatin assembly factor 1 subunit0.709
mus209mutagen-sensitive 2090.674
MED6Mediator complex subunit 60.654
Cap-GCG34438 gene product from transcript CG34438-RF0.647
DlicDynein light intermediate chain0.640
BRWD3CG31132 gene product from transcript CG31132-RA0.639
mus201mutagen-sensitive 2010.619
mus205mutagen-sensitive 2050.588
p53CG33336 gene product from transcript CG33336-RB0.557
CycKCyclin K0.509
rad50CG6339 gene product from transcript CG6339-RD0.506
scrascraps0.450
Tip60CG6121 gene product from transcript CG6121-RA0.441
CkIIbetaCasein kinase II beta subunit0.419
Pp2A-29BProtein phosphatase 2A at 29B0.412
mei-9meiotic 90.373
notnon-stop0.370
CDC45LCG3658 gene product from transcript CG3658-RA0.369
RanGapRan GTPase activating protein0.364
stwlstonewall0.353
MAGECG10059 gene product from transcript CG10059-RA0.347
sxcsuper sex combs0.346
Top1Topoisomerase 10.329
Cdc37CG12019 gene product from transcript CG12019-RA0.294
keykenny0.292
Ge-1CG6181 gene product from transcript CG6181-RA0.283
DrefDNA replication-related element factor0.280
SseSeparase0.277
Mpk2CG5475 gene product from transcript CG5475-RB0.272
CG6066CG6066 gene product from transcript CG6066-RA0.264
mus309mutagen-sensitive 3090.257
CG14641CG14641 gene product from transcript CG14641-RA0.255
scnyscrawny0.252
CSN3COP9 complex homolog subunit 30.252
CG10754CG10754 gene product from transcript CG10754-RA0.251
weeCG4488 gene product from transcript CG4488-RA0.243
tefutelomere fusion0.242
sds22CG5851 gene product from transcript CG5851-RA0.238
glugluon0.234
M6CG7540 gene product from transcript CG7540-RA0.232
eIF-4EEukaryotic initiation factor 4E0.232
CG31301CG31301 gene product from transcript CG31301-RA0.231
imdimmune deficiency0.226
Bap55Brahma associated protein 55kD0.223
aPKCatypical protein kinase C0.223
CSN1bCOP9 complex homolog subunit 1 b0.219
Vap-33-1CG5014 gene product from transcript CG5014-RB0.219
mre11meiotic recombination 110.206
Trf2TATA box binding protein-related factor 20.206
CG10139CG10139 gene product from transcript CG10139-RA0.205
MED31Mediator complex subunit 310.204
AdamCG12131 gene product from transcript CG12131-RA0.204
cdmcadmus0.202
E2f2E2F transcription factor 20.197
dahdiscontinuous actin hexagon0.196
Bj1Bj1 protein0.193
Mcm7Minichromosome maintenance 70.193
KlcKinesin light chain0.192
Eip63EEcdysone-induced protein 63E0.191
Srp54CG4602 gene product from transcript CG4602-RA0.188
Ada2bCG9638 gene product from transcript CG9638-RA0.188
escextra sexcombs0.185
CG8159CG8159 gene product from transcript CG8159-RB0.184
mei-41meiotic 410.177
DNApol-alpha73DNA polymerase alpha 73kD0.176
Mcm3Minichromosome maintenance 30.171
fzyfizzy0.169
BubR1Bub1-related kinase0.165
Caf1-180CG12109 gene product from transcript CG12109-RB0.162
lwrlesswright0.161
alphalphabet0.161
ari-1ariadne0.154
S6kIIRPS6-protein kinase-II0.154
CG17486CG17486 gene product from transcript CG17486-RB0.152
IrbpInverted repeat-binding protein0.151
Mes2CG11100 gene product from transcript CG11100-RB0.151
Uba1Ubiquitin activating enzyme 10.150
U2af50U2 small nuclear riboprotein auxiliary factor 500.149
mus301mutagen-sensitive 3010.148
lin19lin-19-like0.147
LnkCG17367 gene product from transcript CG17367-RC0.147
growlCG14648 gene product from transcript CG14648-RA0.146
mus304mutagen-sensitive 3040.144
dre4CG1828 gene product from transcript CG1828-RB0.139
Fer2LCHFerritin 2 light chain homologue0.137
CG2924CG2924 gene product from transcript CG2924-RA0.136
hayhaywire0.135
Orc2Origin recognition complex subunit 20.135
MTF-1Metal response element-binding Transcription Factor-10.135
DreddDeath related ced-3/Nedd2-like protein0.134
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p531.000
BRCA1breast cancer 1, early onset1.000
RB1retinoblastoma 11.000
CUL2cullin 20.999
CDK2cyclin-dependent kinase 20.998
MDM2Mdm2 p53 binding protein homolog (mouse)0.997
CHEK1CHK1 checkpoint homolog (S. pombe)0.995
E2F1E2F transcription factor 10.989
PCNAproliferating cell nuclear antigen0.988
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.983
CASP3caspase 3, apoptosis-related cysteine peptidase0.969
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.964
CHEK2CHK2 checkpoint homolog (S. pombe)0.960
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.958
PLK1polo-like kinase 10.949
CDK8cyclin-dependent kinase 80.925
SKP2S-phase kinase-associated protein 2 (p45)0.908
NBNnibrin0.905
CLSPNclaspin0.891
MED1mediator complex subunit 10.888
THOC4THO complex 40.865
MCM7minichromosome maintenance complex component 70.839
RAD1RAD1 homolog (S. pombe)0.816
MDC1mediator of DNA-damage checkpoint 10.816
RAD50RAD50 homolog (S. cerevisiae)0.800
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.789
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.771
CCNA2cyclin A20.757
XIAPX-linked inhibitor of apoptosis0.744
ATMataxia telangiectasia mutated0.721
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.720
JUNjun proto-oncogene0.698
RBBP8retinoblastoma binding protein 80.696
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.690
MED28mediator complex subunit 280.664
RBL2retinoblastoma-like 2 (p130)0.664
BRCC3BRCA1/BRCA2-containing complex, subunit 30.651
RFC2replication factor C (activator 1) 2, 40kDa0.650
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.639
MSH6mutS homolog 6 (E. coli)0.618
FOSFBJ murine osteosarcoma viral oncogene homolog0.617
THOC5THO complex 50.615
RPA2replication protein A2, 32kDa0.611
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.596
MAPK6mitogen-activated protein kinase 60.585
CASP2caspase 2, apoptosis-related cysteine peptidase0.584
RPA1replication protein A1, 70kDa0.583
RBL1retinoblastoma-like 1 (p107)0.546
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.539
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.526
MAPK14mitogen-activated protein kinase 140.511
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.508
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.499
FANCD2Fanconi anemia, complementation group D20.476
MED6mediator complex subunit 60.466
UIMC1ubiquitin interaction motif containing 10.466
RAD18RAD18 homolog (S. cerevisiae)0.453
COPS3COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)0.453
BRCA2breast cancer 2, early onset0.446
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.438
BABAM1BRISC and BRCA1 A complex member 10.436
RFC1replication factor C (activator 1) 1, 145kDa0.435
RFC5replication factor C (activator 1) 5, 36.5kDa0.435
TFDP1transcription factor Dp-10.431
FAM175Afamily with sequence similarity 175, member A0.423
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.421
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.415
ORC2origin recognition complex, subunit 20.402
EFTUD2elongation factor Tu GTP binding domain containing 20.402
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.389
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.386
CCND1cyclin D10.383
CNOT1CCR4-NOT transcription complex, subunit 10.376
CDK6cyclin-dependent kinase 60.357
BREbrain and reproductive organ-expressed (TNFRSF1A modulator)0.326
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.316
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.313
SIRT1sirtuin 10.311
HIST1H2BGhistone cluster 1, H2bg0.307
IER3immediate early response 30.296
EME1essential meiotic endonuclease 1 homolog 1 (S. pombe)0.294
CNOT8CCR4-NOT transcription complex, subunit 80.293
THOC2THO complex 20.293
SLX4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)0.283
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.279
POU3F2POU class 3 homeobox 20.278
NEDD8neural precursor cell expressed, developmentally down-regulated 80.275
CDK4cyclin-dependent kinase 40.274
CNOT7CCR4-NOT transcription complex, subunit 70.269
AKT1v-akt murine thymoma viral oncogene homolog 10.263
DDB2damage-specific DNA binding protein 2, 48kDa0.263
CDK1cyclin-dependent kinase 10.257
RBX1ring-box 1, E3 ubiquitin protein ligase0.255
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.255
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.253
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.249
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.243
FADDFas (TNFRSF6)-associated via death domain0.240
COPS2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.239
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.230
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Cdk4cyclin-dependent kinase 40.993
Mapk14mitogen-activated protein kinase 140.921
Brca1breast cancer 10.917
Ptenphosphatase and tensin homolog0.915
Arntlaryl hydrocarbon receptor nuclear translocator-like0.855
Rb1retinoblastoma 10.840
Brca2breast cancer 20.832
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.809
E2f1E2F transcription factor 10.808
Nbnnibrin0.780
Clockcircadian locomotor output cycles kaput0.776
Cdkn1bcyclin-dependent kinase inhibitor 1B0.750
Atmataxia telangiectasia mutated homolog (human)0.705
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.643
Per2period homolog 2 (Drosophila)0.632
Mdm2transformed mouse 3T3 cell double minute 20.622
Atf2activating transcription factor 20.524
Timelesstimeless homolog (Drosophila)0.515
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.479
Msh2mutS homolog 2 (E. coli)0.441
Mdm4transformed mouse 3T3 cell double minute 40.406
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.396
Tcf3transcription factor 30.347
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.326
Ncoa3nuclear receptor coactivator 30.319
SkilSKI-like0.264
Cry1cryptochrome 1 (photolyase-like)0.264
Gtse1G two S phase expressed protein 10.257
Zmym5zinc finger, MYM-type 50.240
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.239
Ruvbl2RuvB-like protein 20.207
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.206
CrebbpCREB binding protein0.199
Mybl2myeloblastosis oncogene-like 20.193
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.192
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.191
Rbl1retinoblastoma-like 1 (p107)0.190
Cdk1cyclin-dependent kinase 10.174
Cry2cryptochrome 2 (photolyase-like)0.158
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.154
H2afxH2A histone family, member X0.146
Apcadenomatosis polyposis coli0.146
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.136
Cops4COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)0.121
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.118
Tcf19transcription factor 190.115
Mapk8mitogen-activated protein kinase 80.109
Parp1poly (ADP-ribose) polymerase family, member 10.109
Skp1aS-phase kinase-associated protein 1A0.106
Ccz1CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)0.104
Ccnb1cyclin B10.101
Raf1v-raf-leukemia viral oncogene 10.100
Smad4MAD homolog 4 (Drosophila)0.099
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.098
Itgb1integrin beta 1 (fibronectin receptor beta)0.097
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.097
Gmnngeminin0.096
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.095
Ccna2cyclin A20.094
Sp1trans-acting transcription factor 10.092
Rfc3replication factor C (activator 1) 30.091
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.088
Ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.088
Xpaxeroderma pigmentosum, complementation group A0.081
Pkm2pyruvate kinase, muscle0.077
Cops3COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)0.077
Ccnb2cyclin B20.077
Ccnfcyclin F0.076
Mlh1mutL homolog 1 (E. coli)0.073
Lig1ligase I, DNA, ATP-dependent0.073
Eif2c2eukaryotic translation initiation factor 2C, 20.073
Rfc2replication factor C (activator 1) 20.072
Nae1NEDD8 activating enzyme E1 subunit 10.071
Nup85nucleoporin 850.069
Ube3aubiquitin protein ligase E3A0.069
Trp73transformation related protein 730.068
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.065
Chaf1bchromatin assembly factor 1, subunit B (p60)0.065
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.064
Rad51ap1RAD51 associated protein 10.063
Per1period homolog 1 (Drosophila)0.059
Lrrk2leucine-rich repeat kinase 20.058
Sfnstratifin0.057
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.057
Aurkbaurora kinase B0.055
Pou5f1POU domain, class 5, transcription factor 10.055
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.054
Hdac1histone deacetylase 10.054
Nononon-POU-domain-containing, octamer binding protein0.054
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.053
DaxxFas death domain-associated protein0.053
Prc1protein regulator of cytokinesis 10.053
Pdpk13-phosphoinositide dependent protein kinase 10.052
Cdt1chromatin licensing and DNA replication factor 10.051
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.050
Orc2origin recognition complex, subunit 20.048
Klf5Kruppel-like factor 50.048
Pcnaproliferating cell nuclear antigen0.048
CblCasitas B-lineage lymphoma0.047
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Oaz1ornithine decarboxylase antizyme 10.124
Pcmtd2protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 20.044
Pkm2pyruvate kinase, muscle0.042
Cdk4cyclin-dependent kinase 40.037
Tcp11l2t-complex 11 (mouse) like 20.035
Snrpasmall nuclear ribonucleoprotein polypeptide A0.035
Top2btopoisomerase (DNA) II beta0.032
Rbbp7retinoblastoma binding protein 70.032
Kdm1lysine (K)-specific demethylase 10.031
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.031
Tnks2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.031
Zfand5zinc finger, AN1-type domain 50.029
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.029
OgtO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.029
Gpiglucose phosphate isomerase0.028
Snrnp70small nuclear ribonucleoprotein 70 (U1)0.028
XiapX-linked inhibitor of apoptosis0.028
Tob1transducer of ErbB-2.10.028
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.028
Sumo3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.027
Pdp1pyruvate dehyrogenase phosphatase catalytic subunit 10.027
Zfand6zinc finger, AN1-type domain 60.027
Tcf12transcription factor 120.026
Daxxdeath-domain associated protein0.026
Pcafp300/CBP-associated factor0.025
Mcm5minichromosome maintenance complex component 50.025
Ctxn1cortexin 10.025
Zfp238zinc finger protein 2380.024
Stub1STIP1 homology and U-Box containing protein 10.024
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.024
Kif2ckinesin family member 2C0.024
Troaptrophinin associated protein0.024
Ccnb1cyclin B10.024
Atf2activating transcription factor 20.023
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.023
Mbtps1membrane-bound transcription factor peptidase, site 10.023
Atxn3ataxin 30.023
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.023
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.022
Pebp1phosphatidylethanolamine binding protein 10.022
Cdca8cell division cycle associated 80.022
Tcfe2atranscription factor E2a0.022
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.022
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.022
Numbnumb homolog (Drosophila)0.022
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.021
Dlg3discs, large homolog 3 (Drosophila)0.021
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.021
Casp2caspase 20.021
Traf4af1TRAF4 associated factor 10.021
Myo16myosin XVI0.021
Usp9xubiquitin specific peptidase 9, X-linked0.021
Mov10Moloney leukemia virus 100.020
Chek1CHK1 checkpoint homolog (S. pombe)0.020
Mier1mesoderm induction early response 1 homolog (Xenopus laevis)0.020
Top2atopoisomerase (DNA) II alpha0.020
H2afxH2A histone family, member X0.020
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.020
Cdc42cell division cycle 42 (GTP binding protein)0.020
Mxi1MAX interactor 10.020
Rbm18RNA binding motif protein 180.020
Lmnb1lamin B10.019
Tymsthymidylate synthetase0.019
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.019
Rcc2regulator of chromosome condensation 20.019
Ccnicyclin I0.019
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.019
Rqcd1rcd1 (required for cell differentiation) homolog 1 (S. pombe)0.019
Sfrs12splicing factor, arginine/serine-rich 120.019
Gyg1glycogenin 10.019
Srfserum response factor (c-fos serum response element-binding transcription factor)0.019
Ttc13tetratricopeptide repeat domain 130.019
Acap2ArfGAP with coiled-coil, ankyrin repeat and PH domains 20.019
Cherpcalcium homeostasis endoplasmic reticulum protein0.019
RGD1561878similar to mKIAA0978 protein0.018
Twsg1twisted gastrulation homolog 1 (Drosophila)0.018
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.018
Rnasenribonuclease type III, nuclear0.018
Ccng2cyclin G20.018
Parp1poly (ADP-ribose) polymerase 10.018
Sesn1sestrin 10.018
Snrpbsmall nuclear ribonucleoprotein polypeptides B and B10.018
Stxbp5syntaxin binding protein 5 (tomosyn)0.018
Ccnfcyclin F0.018
Sdc1syndecan 10.018
Gabarapl2GABA(A) receptor-associated protein like 20.018
Cul3cullin 30.018
Trim47tripartite motif-containing 470.018
Dgkadiacylglycerol kinase, alpha0.018
Mllt6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.018
Lin7clin-7 homolog C (C. elegans)0.017
Nol9nucleolar protein 90.017
Mybl2myeloblastosis oncogene-like 20.017
Ccnb2cyclin B20.017
Ldhblactate dehydrogenase B0.017
Ilkapintegrin-linked kinase-associated serine/threonine phosphatase 2C0.017
Trim28tripartite motif-containing 280.017
Usp32ubiquitin specific peptidase 320.017
Ptbp1polypyrimidine tract binding protein 10.017
Raf1v-raf-leukemia viral oncogene 10.017