The network for 'regulation of response to stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

NameDescriptionProbabilityFunc Analog Organism
KSP1Ksp1p0.979
BCK1Bck1p0.871
YAK1Yak1p0.822
STE20Ste20p0.695
SLT2Slt2p0.647
CTR9Ctr9p0.644
TOR1Tor1p0.639
CRZ1Crz1p0.622
PAF1Paf1p0.614
PPH3Pph3p0.554
TIP41Tip41p0.509
PIL1Pil1p0.470
MIG1Mig1p0.454
PPH21Pph21p0.408
RAD23Rad23p0.390
HOG1Hog1p0.370
GBP2Gbp2p0.344
NBP2Nbp2p0.311
VPS64Vps64p0.309
TOM1Tom1p0.306
STE7Ste7p0.303
BMH1Bmh1p0.297
RGD1Rgd1p0.281
ATG13Atg13p0.270
SSK2Ssk2p0.267
FPK1Fpk1p0.254
CYC8Cyc8p0.248
PBS2Pbs2p0.240
ESA1Esa1p0.215
EAF1Eaf1p0.208
ADR1Adr1p0.208
UBC13Ubc13p0.204
GRR1Grr1p0.202
STE4Ste4p0.195
CTK1Ctk1p0.185
EAF3Eaf3p0.184
VID24Vid24p0.183
CAK1Cak1p0.180
CDC28Cdc28p0.178
FUS3Fus3p0.178
PMT1Pmt1p0.176
PHO81Pho81p0.165
CDC55Cdc55p0.163
VHS1Vhs1p0.162
GAT2Gat2p0.160
SPT5Spt5p0.159
PMT5Pmt5p0.144
BBC1Bbc1p0.143
MIG2Mig2p0.141
PTK2Ptk2p0.139
RGT1Rgt1p0.138
APP1App1p0.137
YPT31Ypt31p0.137
RAD30Rad30p0.136
SNT1Snt1p0.134
YJL193Whypothetical protein0.127
PMT2Pmt2p0.125
HSV2Hsv2p0.120
SPT16Spt16p0.120
YHB1Yhb1p0.120
KOG1Kog1p0.120
ROX1Rox1p0.119
YMR102Chypothetical protein0.118
STE11Ste11p0.118
SKO1Sko1p0.118
YPK1Ypk1p0.116
YPT1Ypt1p0.113
UTP22Utp22p0.111
YJU2Yju2p0.109
ITC1Itc1p0.109
MSN4Msn4p0.105
SOD1Sod1p0.104
HAL5Hal5p0.103
RPN4Rpn4p0.103
RMI1Rmi1p0.101
MON1Mon1p0.100
CKA1Cka1p0.100
SEF1Sef1p0.100
PTP2Ptp2p0.099
SLX5Slx5p0.098
RFX1Rfx1p0.098
TGL3Tgl3p0.098
TSC11Tsc11p0.096
CHD1Chd1p0.095
RAD53Rad53p0.093
ACC1Acc1p0.091
MET4Met4p0.090
CLA4Cla4p0.089
TEC1Tec1p0.087
MNR2Mnr2p0.087
HSL1Hsl1p0.086
SAP155Sap155p0.085
POL30Pol30p0.084
SFB3Sfb3p0.084
RTF1Rtf1p0.084
SEC2Sec2p0.083
YPL014Whypothetical protein0.082
CDC4Cdc4p0.081
NUP157Nup157p0.081
ALO1Alo1p0.081
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
dlk-1Protein DLK-10.133
let-60Protein LET-600.094
egl-18Protein EGL-180.086
elt-6Protein ELT-60.082
swan-2Protein SWAN-20.080
par-5Protein PAR-50.076
sax-3Protein SAX-30.074
acs-4Protein ACS-40.068
alg-1Protein ALG-10.050
frm-7Protein FRM-70.048
CELE_F20D1.3Protein F20D1.30.048
unc-40Protein UNC-400.047
tag-315Protein TAG-3150.046
sma-1Protein SMA-10.043
unc-32Protein UNC-320.037
mig-2Protein MIG-20.035
tag-232Protein TAG-2320.034
eor-1Protein EOR-10.033
apl-1Protein APL-10.032
itr-1Protein ITR-10.032
glp-1Protein GLP-10.032
chk-1Protein CHK-10.032
sem-5Protein SEM-50.032
ebp-2Protein EBP-20.031
nipi-3Protein NIPI-30.031
sym-4Protein SYM-40.031
C34F6.10Protein C34F6.100.031
mat-3Protein MAT-30.031
gmeb-1Protein GMEB-10.030
jnk-1Protein JNK-10.030
egl-44Protein EGL-440.030
rgs-7Protein RGS-70.030
tps-1Protein TPS-10.030
cst-1Protein CST-10.030
F09A5.4Protein F09A5.40.029
F32A5.3Protein F32A5.30.029
sek-1Protein SEK-10.029
lin-25Protein LIN-250.029
sma-6Protein SMA-60.028
miz-1Protein MIZ-10.027
mac-1Protein MAC-10.027
lin-45Protein LIN-450.027
mig-15Protein MIG-150.025
mrt-2Protein MRT-20.025
C48B4.10Protein C48B4.100.024
ser-3Protein SER-30.024
unc-43Protein UNC-430.024
clp-2Protein CLP-20.024
Y82E9BR.13Protein Y82E9BR.130.024
atg-18Protein ATG-180.023
eor-2Protein EOR-20.023
rpn-11Protein RPN-110.023
soc-2Protein SOC-20.023
fln-2Protein FLN-20.023
unc-16Protein UNC-160.023
ceh-44Protein CEH-440.023
mpk-1Protein MPK-10.023
eaf-1Protein EAF-10.022
pas-1Protein PAS-10.022
T23F11.1Protein T23F11.10.022
hil-2Protein HIL-20.022
fli-1Protein FLI-10.022
unc-9Protein UNC-90.022
cki-2Protein CKI-20.021
pbs-7Protein PBS-70.021
fshr-1Protein FSHR-10.021
dep-1Protein DEP-10.021
eps-8Protein EPS-80.021
ncr-1Protein NCR-10.021
dis-3Protein DIS-30.020
gst-7Protein GST-70.020
nhr-6Protein NHR-60.020
ubr-1Protein UBR-10.020
chd-7Protein CHD-70.020
zyg-8Protein ZYG-80.020
dpy-22Protein DPY-220.020
rpt-3Protein RPT-30.019
rgl-1Protein RGL-10.019
F56D12.6Protein F56D12.60.019
hpo-35Protein HPO-350.019
cyk-3Protein CYK-30.019
CELE_H28G03.1Protein H28G03.10.019
K02B12.5Protein K02B12.50.019
sta-1Protein STA-10.018
vab-10Protein VAB-100.018
CELE_F17C11.10Protein F17C11.100.018
otub-1Protein OTUB-10.018
uba-1Protein UBA-10.018
pkn-1Protein PKN-10.018
glr-5Protein GLR-50.018
ect-2Protein ECT-20.018
rpm-1Protein RPM-10.018
bar-1Protein BAR-10.017
afd-1Protein AFD-10.017
C28A5.2Protein C28A5.20.017
lag-1Protein LAG-10.017
dpy-30Protein DPY-300.017
mvb-12Protein MVB-120.017
pde-4Protein PDE-40.017
skn-1Protein SKN-10.017
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fn1fibronectin 10.872
cdh1cadherin 1, epithelial0.795
mmp9matrix metalloproteinase 90.515
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.451
flhfloating head0.352
tbx6T-box gene 60.331
gro1groucho 10.292
dkk1bdickkopf 1b0.249
fgfr3fibroblast growth factor receptor 30.246
epha4aeph receptor A4a0.242
fn1bfibronectin 1b0.239
jag2jagged 20.218
mpxmyeloid-specific peroxidase0.216
meis1myeloid ecotropic viral integration 10.213
pknox1.2pbx/knotted 1 homeobox 1.20.186
znf703zinc finger protein 7030.184
fzd7afrizzled homolog 7a0.184
angptl2angiopoietin-like 20.182
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.179
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.162
eomesaeomesodermin homolog a0.162
socs1suppressor of cytokine signaling 10.154
igf1rbinsulin-like growth factor 1b receptor0.152
si:dkey-18f23.10si:dkey-18f23.100.138
cdc42cell division cycle 420.132
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.131
cry3cryptochrome 30.130
bmperBMP binding endothelial regulator0.129
ptenaphosphatase and tensin homolog A0.127
eporerythropoietin receptor0.126
lppLIM domain containing preferred translocation partner in lipoma0.116
mapk3mitogen-activated protein kinase 30.113
chdchordin0.111
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.110
egr1early growth response 10.108
sox19aSRY-box containing gene 19a0.108
tp63tumor protein p630.106
defbl3defensin, beta-like 30.104
tbx1T-box 10.102
fbln4fibulin 40.099
copacoatomer protein complex, subunit alpha0.098
arf2ADP-ribosylation factor 20.097
ctsl1acathepsin L, 1 a0.097
fgf8afibroblast growth factor 8 a0.096
inspreproinsulin0.093
mvpmajor vault protein0.092
tnfrsfatumor necrosis factor receptor superfamily, member a0.091
spint1aserine peptidase inhibitor, Kunitz type 1 a0.090
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.090
spry2sprouty homolog 20.089
dbx1adeveloping brain homeobox 1a0.089
ppm1aaprotein phosphatase, Mg2+/Mn2+ dependent, 1Aa0.087
fgfr1bfibroblast growth factor receptor 1b0.087
dab1adisabled homolog 1a (Drosophila)0.087
fgf3fibroblast growth factor 30.086
bcl2l10BCL2-like 10 (apoptosis facilitator)0.085
il6rinterleukin 6 receptor0.083
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.080
smad5MAD homolog 5 (Drosophila)0.079
myf5myogenic factor 50.078
slc25a14solute carrier family 25 (mitochondrial carrier, brain), member 140.077
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.076
nr2f5nuclear receptor subfamily 2, group F, member 50.075
nkx6.2NK6 transcription factor related, locus 20.072
znf503zinc finger protein 5030.072
gdnfglial cell derived neurotrophic factor0.072
mmp2matrix metalloproteinase 20.070
cry1acryptochrome 1a0.070
vedventrally expressed dharma/bozozok antagonist0.069
gpibglucose phosphate isomerase b0.068
dnmt4DNA (cytosine-5-)-methyltransferase 40.068
junjun proto-oncogene0.067
lcp1lymphocyte cytosolic plastin 10.066
dusp6dual specificity phosphatase 60.066
creb3l3lcAMP responsive element binding protein 3-like 3 like0.066
tlr9toll-like receptor 90.066
sod1superoxide dismutase 1, soluble0.066
tfatransferrin-a0.065
snrpasmall nuclear ribonucleoprotein polypeptide A0.065
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.064
her1hairy-related 10.064
fgf6afibroblast growth factor 6a0.063
wnt3awingless-type MMTV integration site family, member 3A0.063
prpf4bPRP4 pre-mRNA processing factor 4 homolog B0.060
gata4GATA-binding protein 40.060
ctnnb1catenin (cadherin-associated protein), beta 10.060
LOC557072caspase recruitment domain-containing protein 11-like0.060
adipor1badiponectin receptor 1b0.059
maomonoamine oxidase0.059
her6hairy-related 60.059
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.058
odc1ornithine decarboxylase 10.058
ybx1Y box binding protein 10.057
csnk1dacasein kinase 1, delta a0.057
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.056
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.056
gscgoosecoid0.055
zgc:55558zgc:555580.055
fzd5frizzled homolog 50.054
si:dkey-8l13.4si:dkey-8l13.40.054
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
drkdownstream of receptor kinase0.997
bskbasket0.959
ThorCG8846 gene product from transcript CG8846-RA0.907
stcksteamer duck0.902
dcodiscs overgrown0.894
RelRelish0.893
bazbazooka0.890
rlrolled0.887
Atg1Autophagy-specific gene 10.876
shnschnurri0.851
skpACG16983 gene product from transcript CG16983-RD0.839
DptBDiptericin B0.838
Rho1CG8416 gene product from transcript CG8416-RB0.811
PGRP-LCPeptidoglycan recognition protein LC0.792
keykenny0.790
CG5794CG5794 gene product from transcript CG5794-RB0.783
Dsp1Dorsal switch protein 10.769
dmdiminutive0.752
Atg13Autophagy-specific gene 130.744
Pk61CProtein kinase 61C0.733
Caf1Chromatin assembly factor 1 subunit0.732
Spn27ASerpin 27A0.732
tsrtwinstar0.710
mbcmyoblast city0.705
ChcClathrin heavy chain0.699
pucpuckered0.695
maelmaelstrom0.682
lokloki0.664
Dcp-1Death caspase-10.629
Pi3K92ECG4141 gene product from transcript CG4141-RB0.623
Rab7Rab-protein 70.606
taitaiman0.595
spn-Espindle E0.591
eghegghead0.588
Sin3ACG8815 gene product from transcript CG8815-RC0.583
Hsp83Heat shock protein 830.580
Nrx-IVNeurexin IV0.580
panpangolin0.578
p38bCG7393 gene product from transcript CG7393-RA0.574
PknProtein kinase related to protein kinase N0.568
trolterribly reduced optic lobes0.554
Dcr-2Dicer-20.524
CycDCyclin D0.513
lwrlesswright0.511
ik2IkappaB kinase-like 20.507
grassGram-positive Specific Serine protease0.506
Sp7Serine protease 70.492
Fs(2)KetFemale sterile (2) Ketel0.491
Ptp69DProtein tyrosine phosphatase 69D0.486
Hsp27Heat shock protein 270.482
SPESpatzle-Processing Enzyme0.480
HLHmgammaE(spl) region transcript mgamma0.474
bambag of marbles0.469
hephemipterous0.462
nufnuclear fallout0.461
Adf1Adh transcription factor 10.459
Ras85DRas oncogene at 85D0.459
Sir2CG5216 gene product from transcript CG5216-RA0.456
Lis-1Lissencephaly-10.444
cazcabeza0.437
MtkMetchnikowin0.431
AttAAttacin-A0.429
fs(1)hfemale sterile (1) homeotic0.429
spasspastin0.426
CG14614CG14614 gene product from transcript CG14614-RA0.426
bratbrain tumor0.424
rutrutabaga0.424
S6kIIRPS6-protein kinase-II0.423
PvrPDGF- and VEGF-receptor related0.420
PcPolycomb0.416
Mekk1CG7717 gene product from transcript CG7717-RB0.413
domedomeless0.400
PGRP-SAPeptidoglycan recognition protein SA0.398
Hel25EHelicase at 25E0.398
AGO2Argonaute 20.393
giggigas0.388
Traf4TNF-receptor-associated factor 40.385
Tab2TAK1-associated binding protein 20.376
CaMKIICalcium/calmodulin-dependent protein kinase II0.376
EndoGIEndonuclease G inhibitor0.368
MED19Mediator complex subunit 190.365
Myd88CG2078 gene product from transcript CG2078-RA0.362
CatCatalase0.357
DatDopamine N acetyltransferase0.356
Trx-2thioredoxin-20.354
dshdishevelled0.352
HopHsp70/Hsp90 organizing protein homolog0.351
agoarchipelago0.350
Atg7Autophagy-specific gene 70.343
nmonemo0.342
foxoforkhead box, sub-group O0.339
HLHm5E(spl) region transcript m50.338
AblAbl tyrosine kinase0.330
cactcactus0.330
Lk6CG17342 gene product from transcript CG17342-RA0.327
PGRP-SB1CG9681 gene product from transcript CG9681-RA0.327
Src42ASrc oncogene at 42A0.327
Rya-r44FRyanodine receptor 44F0.325
varivaricose0.322
LysDLysozyme D0.320
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.658
Jak1Janus kinase 10.500
Cd5Cd5 molecule0.490
Fgfr2fibroblast growth factor receptor 20.433
Notch3Notch homolog 3 (Drosophila)0.433
Cd38CD38 molecule0.392
LOC100363783rCG53773-like0.368
C1scomplement component 1, s subcomponent0.363
Gzmkgranzyme K0.344
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.329
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.308
S1pr2sphingosine-1-phosphate receptor 20.295
Ptprhprotein tyrosine phosphatase, receptor type, H0.291
Ccl4chemokine (C-C motif) ligand 40.277
Nek9NIMA (never in mitosis gene a)- related kinase 90.271
Adam7ADAM metallopeptidase domain 70.264
Il6interleukin 60.249
Il12binterleukin 12B0.245
Homer3homer homolog 3 (Drosophila)0.233
C5ar1complement component 5a receptor 10.232
Nr5a2nuclear receptor subfamily 5, group A, member 20.229
Csrp1cysteine and glycine-rich protein 10.225
Gzmbgranzyme B0.225
Vom2r27vomeronasal 2 receptor, 270.223
Reg3aregenerating islet-derived 3 alpha0.223
Hes2hairy and enhancer of split 2 (Drosophila)0.222
Ccbp2chemokine binding protein 20.219
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.217
Il1r1interleukin 1 receptor, type I0.215
Ucnurocortin0.205
Srgnserglycin0.202
Vcam1vascular cell adhesion molecule 10.201
Ccr2chemokine (C-C motif) receptor 20.199
Adora3adenosine A3 receptor0.192
Gipgastric inhibitory polypeptide0.191
Gja1gap junction protein, alpha 10.190
S100a9S100 calcium binding protein A90.190
Ednrbendothelin receptor type B0.183
Xcl1chemokine (C motif) ligand 10.179
S100a8S100 calcium binding protein A80.178
Socs3suppressor of cytokine signaling 30.178
Muskmuscle, skeletal, receptor tyrosine kinase0.177
Trim47tripartite motif-containing 470.174
Cpb1carboxypeptidase B1 (tissue)0.170
Ccl2chemokine (C-C motif) ligand 20.169
Psmb7proteasome (prosome, macropain) subunit, beta type 70.167
Il4rainterleukin 4 receptor, alpha0.165
Mmp13matrix metallopeptidase 130.164
Il13interleukin 130.163
Tcf4transcription factor 40.162
Nrg1neuregulin 10.160
Il4interleukin 40.159
Cd302CD302 molecule0.158
Slco2b1solute carrier organic anion transporter family, member 2b10.154
Fgf7fibroblast growth factor 70.154
Mapk1mitogen activated protein kinase 10.154
Hoxa2homeo box A20.153
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.153
Vegfavascular endothelial growth factor A0.152
Oprm1opioid receptor, mu 10.151
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.150
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.148
Prp15proline-rich protein 150.148
Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin0.147
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.146
Olr1496olfactory receptor 14960.144
Errfi1ERBB receptor feedback inhibitor 10.144
Cpb2carboxypeptidase B2 (plasma)0.142
Ccr5chemokine (C-C motif) receptor 50.140
Pla1aphospholipase A1 member A0.138
RGD1564865similar to 20-alpha-hydroxysteroid dehydrogenase0.138
Anxa7annexin A70.137
RT1-BaRT1 class II, locus Ba0.137
GperG protein-coupled estrogen receptor 10.137
Jak2Janus kinase 20.135
Il8rbinterleukin 8 receptor, beta0.134
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.133
F2rl1coagulation factor II (thrombin) receptor-like 10.132
Csf1colony stimulating factor 1 (macrophage)0.130
Scn11asodium channel, voltage-gated, type XI, alpha0.129
Lpllipoprotein lipase0.126
Prrx1paired related homeobox 10.123
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.123
Csn1s1casein alpha s10.123
Nfibnuclear factor I/B0.122
Prkcgprotein kinase C, gamma0.121
RGD1310262hypothetical LOC3046500.119
Metmet proto-oncogene0.119
Gpr176G protein-coupled receptor 1760.119
Igsf6immunoglobulin superfamily, member 60.117
Psma7proteasome (prosome, macropain) subunit, alpha type 70.115
LOC290577hypothetical LOC2905770.115
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.115
Ccl3chemokine (C-C motif) ligand 30.114
Grm7glutamate receptor, metabotropic 70.114
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.114
Zyxzyxin0.112
Testintestin gene0.112
Cskc-src tyrosine kinase0.110
Tlr4toll-like receptor 40.110