The network for 'cranial suture morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cranial suture morphogenesis

The process in which any suture between cranial bones is generated and organized.

NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.973
fgf10afibroblast growth factor 10a0.654
gpr126G protein-coupled receptor 1260.537
dlx5adistal-less homeobox gene 5a0.526
hand2heart and neural crest derivatives expressed transcript 20.391
fgf24fibroblast growth factor 240.347
msxcmuscle segment homeobox C0.300
msxdmuscle segment homeobox D0.298
sox9aSRY-box containing gene 9a0.290
tbx2aT-box gene 2a0.274
pax9paired box gene 90.267
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.266
bmp2abone morphogenetic protein 2a0.261
tbx1T-box 10.257
col10a1collagen, type X, alpha 10.256
dlx4adistal-less homeobox gene 4a0.238
sparcsecreted acidic cysteine rich glycoprotein0.233
prdm1aPR domain containing 1a, with ZNF domain0.210
tcf7transcription factor 7 (T-cell specific, HMG-box)0.177
col2a1acollagen type II, alpha-1a0.173
tbx5aT-box 5a0.173
tbx18T-box 180.163
nkx3.2NK3 homeobox 20.162
twist3twist30.139
dlx2adistal-less homeobox gene 2a0.138
cx43connexin 430.119
nkx2.5NK2 transcription factor related 50.114
fras1Fraser syndrome 10.093
itga3bintegrin, alpha 3b0.093
myl7myosin, light polypeptide 7, regulatory0.092
myod1myogenic differentiation 10.091
ctgfconnective tissue growth factor0.083
egr1early growth response 10.080
jag1bjagged 1b0.079
igfbp3insulin-like growth factor binding protein 30.078
sema3dsemaphorin 3d0.077
dlx2bdistal-less homeobox gene 2b0.073
zgc:111821zgc:1118210.073
spry4sprouty (Drosophila) homolog 40.071
fgfr1afibroblast growth factor receptor 1a0.067
tgfb3transforming growth factor, beta 30.066
crip2cysteine-rich protein 20.065
sp7Sp7 transcription factor0.065
hoxa13bhomeo box A13b0.065
hapln1ahyaluronan and proteoglycan link protein 1a0.063
edn1endothelin 10.063
cyp1acytochrome P450, family 1, subfamily A0.058
tgfb2transforming growth factor, beta 20.057
wnt11rwingless-type MMTV integration site family, member 11, related0.056
fgf20afibroblast growth factor 20a0.054
col1a1acollagen, type I, alpha 1a0.053
dlx6adistal-less homeobox gene 6a0.053
runx2arunt-related transcription factor 2a0.053
angptl7angiopoietin-like 70.051
tnctenascin C0.049
bmperBMP binding endothelial regulator0.048
tbx5bT-box 5b0.048
si:ch211-173b8.2si:ch211-173b8.20.048
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.047
npntnephronectin0.047
ptch2patched 20.045
bmp4bone morphogenetic protein 40.043
alcamaactivated leukocyte cell adhesion molecule a0.041
mab21l2mab-21-like 20.040
lama5laminin, alpha 50.039
ednraendothelin receptor type A0.039
dlx4bdistal-less homeobox gene 4b0.039
fli1afriend leukemia integration 1a0.038
dlx3bdistal-less homeobox gene 3b0.038
rargaretinoic acid receptor gamma a0.038
vcanaversican a0.036
col11a2collagen type XI alpha-20.036
LOC100000500sclerostin-like0.034
lhx6LIM homeobox 60.034
hoxd13ahomeo box D13a0.032
notch1bnotch homolog 1b0.031
kitakit receptor a0.031
cx30.3connexin 30.30.030
mgpmatrix Gla protein0.030
evx1even-skipped homeobox 10.029
ltbp3latent transforming growth factor beta binding protein 30.029
barx1BarH-like homeobox 10.028
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.028
nkx2.3NK2 transcription factor related 30.027
efnb3bephrin B3b0.026
tgfbitransforming growth factor, beta-induced0.025
tbx20T-box 200.025
osr1odd-skipped related 1 (Drosophila)0.024
si:dkeyp-51c11.1si:dkeyp-51c11.10.024
fgfrl1afibroblast growth factor receptor-like 1a0.024
zgc:110712zgc:1107120.024
frem2aFras1 related extracellular matrix protein 2a0.022
lama4laminin, alpha 40.021
vmhcventricular myosin heavy chain0.021
col5a1procollagen, type V, alpha 10.021
prrx1apaired related homeobox 1a0.020
slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.020
nav3neuron navigator 30.020
frem3Fras1 related extracellular matrix 30.019
bmp7bbone morphogenetic protein 7b0.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Gli3GLI-Kruppel family member GLI31.000
Prrx1paired related homeobox 10.996
Otx2orthodenticle homolog 2 (Drosophila)0.994
Pax3paired box gene 30.991
Pax6paired box gene 60.990
Msx1homeobox, msh-like 10.989
Gli2GLI-Kruppel family member GLI20.970
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.966
Neurod1neurogenic differentiation 10.963
Fgfr2fibroblast growth factor receptor 20.952
Eya1eyes absent 1 homolog (Drosophila)0.951
Fgf10fibroblast growth factor 100.945
Foxc1forkhead box C10.944
Foxg1forkhead box G10.941
Chrdchordin0.937
Tcfap2atranscription factor AP-2, alpha0.925
Pax2paired box gene 20.915
Fgf8fibroblast growth factor 80.915
Tgfb2transforming growth factor, beta 20.911
Tbx1T-box 10.897
Msx2homeobox, msh-like 20.894
Fgfr1fibroblast growth factor receptor 10.876
Smosmoothened homolog (Drosophila)0.860
Hand2heart and neural crest derivatives expressed transcript 20.841
Prrx2paired related homeobox 20.837
Sox9SRY-box containing gene 90.816
Pitx2paired-like homeodomain transcription factor 20.778
Foxc2forkhead box C20.748
Gscgoosecoid homeobox0.716
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.702
Dlx5distal-less homeobox 50.701
Nodalnodal0.701
Gbx2gastrulation brain homeobox 20.668
Ror2receptor tyrosine kinase-like orphan receptor 20.635
Ascl1achaete-scute complex homolog 1 (Drosophila)0.588
Hoxa1homeobox A10.555
Bmp7bone morphogenetic protein 70.544
Lmx1aLIM homeobox transcription factor 1 alpha0.510
En1engrailed 10.509
Bmp4bone morphogenetic protein 40.497
Sox2SRY-box containing gene 20.496
Meox2mesenchyme homeobox 20.474
Zeb1zinc finger E-box binding homeobox 10.405
Fgfr3fibroblast growth factor receptor 30.388
Twist2twist homolog 2 (Drosophila)0.385
Runx2runt related transcription factor 20.384
Hoxd13homeobox D130.358
Isl1ISL1 transcription factor, LIM/homeodomain0.340
Hand1heart and neural crest derivatives expressed transcript 10.316
Tbx15T-box 150.299
Alx4aristaless-like homeobox 40.289
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.286
Neurog3neurogenin 30.281
Rargretinoic acid receptor, gamma0.279
Hoxa11homeobox A110.235
Zic3zinc finger protein of the cerebellum 30.208
Pax9paired box gene 90.205
Fgf9fibroblast growth factor 90.202
Hoxd11homeobox D110.199
Rspo2R-spondin 2 homolog (Xenopus laevis)0.198
Pitx1paired-like homeodomain transcription factor 10.165
Nognoggin0.159
Neurog2neurogenin 20.155
Rarbretinoic acid receptor, beta0.142
Tgfbr2transforming growth factor, beta receptor II0.121
Fgf15fibroblast growth factor 150.111
Lmx1bLIM homeobox transcription factor 1 beta0.110
Nr5a1nuclear receptor subfamily 5, group A, member 10.108
Acvr1activin A receptor, type 10.108
Pou4f3POU domain, class 4, transcription factor 30.100
Ntf3neurotrophin 30.091
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.091
Lhx1LIM homeobox protein 10.085
Hoxd3homeobox D30.083
Emx1empty spiracles homolog 1 (Drosophila)0.079
Ednraendothelin receptor type A0.078
Insm1insulinoma-associated 10.076
Hoxa13homeobox A130.074
Atoh7atonal homolog 7 (Drosophila)0.074
Nhlh1nescient helix loop helix 10.074
Emx2empty spiracles homolog 2 (Drosophila)0.068
Otx1orthodenticle homolog 1 (Drosophila)0.067
Ptch1patched homolog 10.066
Dkk1dickkopf homolog 1 (Xenopus laevis)0.063
Pou4f2POU domain, class 4, transcription factor 20.062
Sox11SRY-box containing gene 110.062
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.061
Foxh1forkhead box H10.060
Tbx3T-box 30.057
Nkx3-2NK3 homeobox 20.054
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.052
Lhx5LIM homeobox protein 50.051
Gdf1growth differentiation factor 10.049
Pdx1pancreatic and duodenal homeobox 10.049
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.047
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.042
Gata1GATA binding protein 10.042
Ptf1apancreas specific transcription factor, 1a0.040
Rararetinoic acid receptor, alpha0.039
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fgfr1Fibroblast growth factor receptor 10.231
Ptpn14protein tyrosine phosphatase, non-receptor type 140.124
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.064
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.057
Unc5bunc-5 homolog B (C. elegans)0.051
Fstl1follistatin-like 10.049
Col12a1collagen, type XII, alpha 10.047
Fgfr2fibroblast growth factor receptor 20.047
Muskmuscle, skeletal, receptor tyrosine kinase0.045
Tln1talin 10.044
Sod3superoxide dismutase 3, extracellular0.041
Bgnbiglycan0.035
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.035
Bmp6bone morphogenetic protein 60.033
Aebp1AE binding protein 10.029
Foxd3forkhead box D30.029
Olfml2bolfactomedin-like 2B0.027
Bcl2l2Bcl2-like 20.027
Arhgap23Rho GTPase activating protein 230.025
Rcn3reticulocalbin 3, EF-hand calcium binding domain0.025
Fxyd5FXYD domain-containing ion transport regulator 50.024
Nppcnatriuretic peptide precursor C0.024
Clec11aC-type lectin domain family 11, member a0.023
Adam7ADAM metallopeptidase domain 70.022
Acanaggrecan0.020
Acta2smooth muscle alpha-actin0.020
RGD1565057similar to hypothetical protein FLJ328710.020
Smad7SMAD family member 70.019
C1qtnf3C1q and tumor necrosis factor related protein 30.019
Mmp23matrix metallopeptidase 230.018
Msnmoesin0.018
Edn1endothelin 10.017
Igfbp5insulin-like growth factor binding protein 50.016
Ng23Ng23 protein0.016
Hrhairless0.016
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.016
Myh9myosin, heavy chain 9, non-muscle0.014
RGD1564327similar to integrin alpha 80.014
Crygfcrystallin, gamma F0.014
Bglapbone gamma-carboxyglutamate (gla) protein0.014
Shroom1shroom family member 10.014
Nek9NIMA (never in mitosis gene a)- related kinase 90.014
Prkchprotein kinase C, eta0.014
Mcammelanoma cell adhesion molecule0.013
Tulp1tubby like protein 10.013
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.013
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.013
Hand2heart and neural crest derivatives expressed 20.013
Aqp4aquaporin 40.013
Timp2TIMP metallopeptidase inhibitor 20.013
Pftk1PFTAIRE protein kinase 10.013
Kcnk1potassium channel, subfamily K, member 10.012
Hapln1hyaluronan and proteoglycan link protein 10.012
Apcsamyloid P component, serum0.012
Sc65synaptonemal complex protein SC650.012
Ecel1endothelin converting enzyme-like 10.012
Lect1leukocyte cell derived chemotaxin 10.012
Tgfbr2transforming growth factor, beta receptor II0.012
S1pr2sphingosine-1-phosphate receptor 20.012
Col9a1collagen, type IX, alpha 10.011
Loxl1lysyl oxidase-like 10.011
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.011
Fzd2frizzled homolog 2 (Drosophila)0.011
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.011
Mstnmyostatin0.010
Myh13myosin, heavy chain 13, skeletal muscle0.010
Fapfibroblast activation protein, alpha0.010
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.010
Myl9myosin, light chain 9, regulatory0.010
Plxdc2plexin domain containing 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism